Abstract: A method of administering a reduced pressure tissue treatment to a tissue site includes percutaneously inserting a tube through a skin tissue of a patient to place a distal end of the tube adjacent the tissue site, the tube having at least one passageway. A balloon associated with the tube is positioned adjacent the tissue site, and the balloon is inflated to dissect and form a void adjacent the tissue site. A manifold having a plurality of flow channels is delivered through the passageway to the tissue site. The manifold is positioned such that at least one of the flow channels is in contact with the tissue site, and a reduced pressure is applied to the tissue site through the flow channels of the manifold.

Abstract: An air shot or priming mechanism for an injection pen. The injection pen comprises a cartridge-holder and a housing. The cartridge-holder interacts with a nut-member capable of driving the piston rod forward when relatively rotated. The cartridge-holder is rotational coupled to the housing such that rotation of the cartridge-holder relatively to the housing causes the nut-member and the piston rod to rotate relatively, thus the relative angular rotation between the cartridge-holder and the housing determines the size of the air shot so performed.

Abstract: An access port assembly having an attachable catheter allows for inserting a guidewire into the catheter to aid in the placement of the integral catheter while still attached to the access port assembly. A method is described for placing an access port fixedly attached to a catheter into a patient using a guidewire inserted into the catheter.

Abstract: This invention concerns treating apparently normal tissue surrounding sites of cancerous tumors so as to reduce both the probability of a recurrence of cancer at and near the site of a cancerous tissue, and to reduce the amount of apparently healthy tissue that is usually excised along with the tumor, thereby providing a substantial benefit to the cancer patient by eliminating or delaying tumor recurrence and sparing normal tissue for its functionality and for avoiding unnecessary disfigurement.

Abstract: RFID chip (214) having various types of data is mounted on liquid syringe (200). Chemical liquid injector (100) obtains the various types of data from RFID chip (214) to perform a predetermined operation in accordance with at least some of the various types of data. For, example, a variable pattern for liquid can be recorded on RFID chip (214) of liquid syringe (200) to allow chemical liquid injector (100) to inject the liquid in accordance with the predetermined variable pattern. Thus, a large amount of data can be easily input to the chemical liquid injector to perform the various operations.

Abstract: An infusion pump is provided with a slide clamp mechanism having a clamp member for closing or opening an infusion tube and a valve mechanism for pressing the infusion tube to stop flow of a solution in the infusion tube and has a structure where an interlocking mechanism for interlocking the slide clamp mechanism with the valve mechanism only by manipulation of a handle is disposed. During a series of manipulations of the handle, the infusion tube is always closed by one or both of the slide clamp and valves 14A and 14B, so that free flow of a solution in the infusion tube 40 can be entirely prevented.

Abstract: Provided is a microneedle unit comprising a case having a space accommodating a fluid and a fluid channel through which the fluid is discharged, a microneedle coupled to a lower portion of the case, a base cover disposed at the lower portion of the case, having a hole through which the microneedle passes, and being vertically movable, a guide pin coupled to the base cover and configured to open and close the fluid channel, and an elastic member configured to impart a restoring force such that the base cover is moved upward by an external pressure and then returns downward again. Therefore, the microneedle unit, which is provided to deliver a fluid into the skin with no pain and no scar, can control injection of the fluid using the guide pin, and repeatedly and conveniently control injection of the fluid using the elastic member.

Abstract: An injection device for injecting a substance from an ampoule inserted in the device, the device including one or more of the following components: an internal thread for engaging a threaded rod, the internal thread including several contact faces enabling the use of a different threaded rods, a real-time display for displaying a quantity of a substance, e.g., the quantity to be injected or dispensed, the quantity available for dispensing or the quantity dispensed, a mechanical lock for locking the device prior to inserting the ampoule, and a claw lock for preventing use of the injection device.

Abstract: Embodiments include an infusion-occlusion system having a delivery catheter, a guide catheter adapted to receive the delivery catheter, and a guidewire with an occlusion device adapted to be received within the guide catheter. The guide catheter of the catheter kit may be provided with an occlusion device at the distal end of the guide catheter. The delivery catheter may have an accessory lumen, coaxial or co-linear lumen, a supporting mandrel, or an occlusion device at its distal end. Moreover, according to some embodiments, occlusion devices may be a single material or a composite balloon having an inner liner and an outer layer of different materials, a high compliance low pressure balloon, or a filter device that restricts particles from passing through but does not restrict fluid, such as blood. An inflation device with a large volume and low volume syringe can be used to inflate the balloon.

Abstract: Devices and methods for transmucosal drug delivery are provided. A device includes a housing configured for intralumenal deployment into a human or animal subject; a drug-dispensing portion which contains at least one drug; and a plurality of microneedles extending, or being extendable from, the housing, the plurality of microneedles being configured to disrupt at least one region of a mucosal barrier adjacent the housing at a selected time after being intralumenally deployed in the human or animal subject. The device is operable to dispense the drug from the housing to a region of the mucosal barrier disrupted by the plurality of microneedles.

Abstract: A syringe adapter with a ball-typed valve has a base, a dosing tube mounted around the base and a resilient valve mounted in the base and the dosing tube. The base has a guiding groove and an inner liquid channel communicating with each other, as well as an exhaust channel. Liquid medicine injected into the syringe adapter flows through the guiding groove and causes the inner liquid channel to be injected into a patient's body. The liquid medicine remaining in the split is cleaned when cleaning fluid is injected to clean the syringe adapter. Air in the syringe adapter flows out through the exhaust channel and is not injected into the patient's body, so the patient is free from pain. Furthermore, elements and assembling processes of the syringe adapter are simplified and manufacturing cost of the syringe adapter is lowered.

Abstract: Intralumenal devices and methods are provided for transmucosal drug delivery. The device may comprise a housing configured for intralumenal deployment into a human or animal subject; a drug-dispensing portion which contains at least one drug; and an electrically-actuatable portion configured to disrupt at least one region of a mucosal barrier adjacent to the housing at a selected time while intralumenally deployed in the human or animal subject. The device may be operable to dispense the drug from the housing to a region of the mucosal barrier disrupted by the electrically-actuatable portion.

Abstract: The invention is a non-surgical method for the eradication of pigmentation and scar tissue from an area of skin. The method comprises repeatedly puncturing the area of skin with an array of needles. As the needles are inserted into the skin, the needles and surface of the skin are washed with a clean solution. As the needles are withdrawn from the skin, the flow of clean solution ceases and the dirty solution, which contains cellular fluids and pigments released by the action of the needles, is removed from the surface. The invention is also a solution, which is used to clean the needles and to aid in destroying the pigment containing cells, and an apparatus, which is especially designed to move the needles into and out of the surface of the skin and to provide synchronization of the motion of the needles and flow of the solution such as to maximize the effectiveness of the method.

Abstract: Systems and methods for providing multiple pass continuous flow dialysis therapy are provided. The present invention includes a fluid circuit connected to a patient via a catheter thereby defining a fluid loop along which a therapy fluid including a dialysate can be continuously circulated into, through and out of a peritoneal cavity of a patient to remove a therapeutically effective amount of excess water and solutes including uremic toxins. The feed rate and discharge rate of therapy fluid into the fluid loop can be controllably regulated in proportion to the circulation rate of fluid in the fluid loop such that the therapy fluid can pass a multiple number of times along the fluid loop prior to discharge.

Abstract: An insertion device for infusion sets, comprising a housing for enclosing an infusion set, a drive device for displacing the infusion set for insertion, wherein a portion of the drive device moves in an insertion direction, the movement being substantially friction-free relative to the housing.

Abstract: Some embodiments an infusion pump system can provide a suggested bolus dosage based on particular parameters (e.g., the user's recent blood glucose characteristics, food intake data, an amount of insulin already delivered to the user which has not yet acted on the user, or other factors). In some circumstances, the infusion pump system can receive information indicative of the user's blood glucose level and suggest an insulin bolus dosage that is at least partially dependent upon the recent rate of change in the user's blood glucose level. Such a feature can be helpful to a user when the infusion pump is operated in conjunction with a glucose monitoring device because the suggested bolus dosage can be at least partially based on recent data indicative of the user's blood glucose level.

Abstract: The present invention provides a method whereby a drug can be conveniently injected into the living body, without sticking a needle, from a device that is not in contact with the living body, and a device therefor. Specifically provided is a method for injecting a peptide drug such as insulin, and a device therefor. No special consumables are needed except the drug solution or suspension. The method and device comprise injecting a drug into the living body by electrospraying a solution or suspension of the drug from a nozzle to which high voltage is applied and which is not in contact with the living body.

Abstract: An electrosurgical apparatus includes a housing having a shaft extending therefrom. The shaft includes an end effector assembly at a distal end thereof. The end effector assembly includes first and second fixed jaw members in spaced relation relative to one another. An electrically conductive tissue sealing plate is operatively coupled to each of the jaw members. The electrically conductive seal plates are adapted to connect to an electrosurgical energy source and communicate with a control system. The control system is configured to regulate the delivery of electrosurgical energy from the source of electrosurgical energy to the tissue sealing plate on each of the jaw members. A guide channel is disposed between the pair of fixed jaw members and extends proximally along the shaft from the distal end thereof. A knife is disposed at a proximal end of the guide channel and is configured to selectively cut tissue in a distal direction.

Abstract: An access port for providing subcutaneous access to a patient is disclosed. The access port includes a septum including palpable identification indicia thereon. In particular, the access port in one embodiment includes a body that defines a fluid cavity and a needle-penetrable septum covering the fluid cavity for providing access thereto. The septum defines an outer periphery. One or more palpation features are included on the septum. The palpation features each include a portion that extends in a radial direction beyond the outer periphery of the septum. The palpation features are therefore disposed relatively farther away from each other, simplifying palpation and identification thereof after the port has been subcutaneously implanted into a patient. The palpation features can be indicative of an attribute of the port, such as its ability to withstand fluid pressures and flow rates associated with power injection, for instance.

Abstract: Various sealing structures are used in a front-loading injector, for preventing leakage of spilled fluid from an external surface of a syringe into the vicinity of the drive ram. For example, a sealing gasket may be incorporated into the front face of the injector housing, for mating to the rearward circular edge of the cylindrical body of a syringe. Alternatively, sealing and locking functions may be performed by a single structure on the rearward end of the syringe. Further, leakage may be prevented by including a non-planar sealing flange on the syringe, positioned on the syringe forward of the locking structure, or by a two-piece structure, including a syringe and a separate leakage stopping washer for surrounding the syringe to halt the flow of fluid along the exterior of the syringe. (As part of this aspect, or as an independent feature, the syringe may include an annularly discontinuous flange forward of the locking structure, for providing mechanical support for the syringe against the injector.