Abstract: A self-injection device (101) for delivering a medicament includes a housing (111), and a needle (103) connected to the housing (111). A compressible reservoir (121) is connected to the housing (111) and is in fluid communication with a needle (103) such that compressing the reservoir (121) delivers medicament from the reservoir (121) to the needle (103) and moves the needle (103) from the first position to the second position. A platform (171) is disposed within the housing (111) about which the housing (111) is rotatable between a plurality of positions. Each of the positions corresponds to a different distance the needle (103) is moved to the second position during an injection to provide a variable injection depth. The needle (103) is withdrawn into the housing (111) after an injection without requiring manual manipulation by the user, thereby preventing needle sticks and other accidents.

Abstract: A method for controlling delivery of energy to seal and divide tissue includes applying energy to tissue in a first phase through an electrosurgical forceps having at least one electrically energizable electrode. The method also includes detecting a predetermined condition based on the application of energy to tissue during the first phase. The method also includes applying energy to tissue during a second phase upon detection of the predetermined condition and providing tension to the tissue during the second phase to separate the tissue.

Abstract: An introducer sheath, which is formed from a tubular member provided with a hollow portion through which an elongated body is freely insertable, and which includes a distal portion and a main body portion, wherein the inner diameter of the distal portion is formed to become gradually smaller toward the distal side, and on the inner surface of the distal portion, there is provided a hydrophobic coating having a friction coefficient lower than the friction coefficient of the tubular member.

Abstract: The device comprises a syringe (10, 11, 12) and safety means comprising a protective sheath (16) capable of adopting, relative to the syringe body, both an injection configuration in which the syringe needle (11) projects beyond said sheath, and a protection configuration in which the needle extends inside the sheath. The device includes a trigger member (30) enabling it to pass from the injection configuration to the protection configuration at the end of the injection stroke. It comprises means (34) for defining a first end-of-injection-stroke situation in which the trigger member (30) is unsuitable for causing the device to pass from the injection configuration to the protection configuration, and a second end-of-injection-stroke situation in which such passage is possible.

Abstract: Various structures are used in a front-loading injector, for mounting the syringe to the injector and/or preventing leakage of spilled fluid from an external surface of a syringe into the vicinity of the drive ram. A conically-shaped structure on the rearward end of the syringe is specifically disclosed.

Abstract: A gravity fed infant feeding device is disclosed. The gravity feeding device may have a cover with a through hole that allows liquid nutrients within the infant feeding device to be fed to an infant by way of gravity. If the infant feeding device clogs up, then either an integrated pump or a separate pump may be applied to the infant feeding device to increase pressure and push out the clog from the system. the through hole may be covered with a hydrophobic filter to allow air to pass there through and allow the feeding of the infant by way of gravity yet liquid nutrients within the infant feeding device cannot escape or be contaminated during use.

Abstract: A pen needle or pen needle cap assembly is designed to be manually attached e.g. by screwing onto an injection device, and is provided with a gripping region designed to allow the torque that can be applied in the tightening sense to be less than that which can be applied in the loosening sense.

Abstract: A method for injection of an imaging contrast into a patient, includes: a. in a first phase, injecting a fluid having a first concentration of contrast agent for a first period of time; and b. in a second phase, injecting a fluid having a second concentration of contrast agent for a second period of time. The osmolarity of the second phase is higher than the osmolarity of the first phase. The method can further include: c. in a third phase, subsequent to the second phase, injecting a fluid having a third concentration of contrast agent for a third period of time. The osmolarity of the third phase is lower than the osmolarity of the second phase. In embodiments in which the composition of the contrast agent of the third phase is the same as the composition of the contrast agent of the second phase, the third concentration can be lower than the second concentration.

Abstract: The invention relates to a device comprising a syringe body (10) having an axial direction (A) and a bearing sleeve (18) inside which the body is arranged. The sleeve has at least one holding lug (22) co-operating with the syringe body, at a proximal end (10A) of the latter, in order to hold the body in relation to the sleeve. Said proximal end is fixed to a wedging surface (42) having radial crenulations forming dips (42B) and bumps (42A) and the holding lug is inserted into a dip in order to prevent a relative rotation of the syringe body (10) and the sleeve perpendicularly to the axial direction.

Abstract: Multilayer electrodes, electrode systems, and stimulation systems are disclosed. An electrode may include a conductive layer with a unitary tail, a connector disposed on a distal end of the tail, and a nonconductive top layer disposed along a top portion of the conductive layer. An electrode may include a magnetic lead connector socket, or a receptacle formed by a depression in the conductive layer configured to receive a male connector. An electrode system may include a plurality of conductive zones and a plurality of connectors. A stimulation system may include an electronics layer in electrical contact with a conductive layer via a puncture connection, and may provide an iontophoretic treatment followed by a TENS treatment. Other electrodes, systems and methods are also disclosed.

Abstract: The invention relates to a device for oral application of a composition. The device comprises recess having an outer rim encompassing the recess. Within the recess, a composition is arranged. The composition comprises a gelling agent and an active agent. A cover member is attached to the rim and completely covers the recess. Thus, the cover member, together with the recess, retains the composition within the recess. The cover member has an outer surface opposed to an inner surface adjoining the recess. In order to allow preparation of the composition by adding water without the risk of losing some of the composition during preparation, the cover member comprises one or more openings for providing fluidic connection between the inner surface and the outer surface. Through this opening, water can enter for preparing the composition meanwhile the cover retains all composition within the recess. The invention further relates to a method for manufacturing the device.

Abstract: The present invention relates to a syringe for treating facial wrinkles having a syringe cylinder, a needle body detachably mounted at the front end portion of the syringe cylinder and having a syringe needle disposed thereon, and a piston rod disposed inside the syringe cylinder for operating a piston, the syringe including: the syringe cylinder formed of a substantially thin tube having an inside diameter in a range of 2.0 mm to 7.0 mm; and an inflow check valve disposed at one side of the front end portion of the syringe cylinder so as to supply a predetermined quantity of gas to the interior of the syringe cylinder, wherein the predetermined quantity of gas supplied through the inflow check valve to the interior of the syringe cylinder and a predetermined quantity of liquid filled into the syringe cylinder are injected in turn into the dermis of the skin, which is repeatedly carried out.

Abstract: A medication delivery device (1) comprises an indicator element (3) having indications (300) and a magnifying device located over an indication position (32). The magnifying device (4) comprises an optical system (5) with a magnifying lens (43) wherein the optical system (5) is constructed such that the optical path length between the indication position (32) and the magnifying lens (43) is enlarged. As an example, the medication delivery device (1) is a pen-type device, wherein a dose dial element (30) having a dosage scale (31) is disposed. The magnifying device (4) generates a magnified image of the dosage scale (31) so that the size of the selected dose (33) of the medical product is visible through a window (41). A method for assembling the medication delivery device (1) includes providing a medication delivery device (1) having a receptacle and mounting an element of the magnifying device (4) at the receptacle.

Abstract: Various handheld medical dispensing configurations and methods including the following: Handheld medical dispensing system comprises a syringe, which has a plunger, releasably mounted to syringe actuation apparatus, the apparatus having an actuator configured such that it can move the plunger more than once to dispense a plurality of amounts of substance from the syringe. A method of dispensing fluid from a syringe comprises holding a medical substance delivery system including a syringe, which has a needle, and which is secured to syringe actuation apparatus configured to dispense predetermined amounts of the substance from the syringe, penetrating the needle at one patient site and using the apparatus to deliver a predetermined amount of the substance, and penetrating the needle at another patient site and using the apparatus to deliver a predetermined amount of the substance.

Abstract: Various diagnostic procedures and devices are used to perform imaging studies, mucus flow studies, air/gas flow studies, anatomic dimension studies, endoscopic studies and transillumination studies. Devices and methods for visually confirming the positioning of a distal end portion of an illuminating device placed within a patient include inserting a distal end portion of an illuminating device internally into a patient, emitting light from the distal end portion of the illuminating device, observing transillumination resulting from the light emitted from the distal end portion of the illuminating device that occurs on an external surface of the patient, and correlating the location of the observed transillumination on the external surface of the patient with an internal location of the patient that underlies the location of observed transillumination, to confirm positioning of the distal end portion of the illuminating device.

Abstract: A device for controlling fluid flow through an indwelling catheter assembly. The device includes a septum that is closed by default but that may be defeated temporarily by either exerting a force on a contact surface of the septum, or by biasing the septum with a probe.

Abstract: A piston rod for an injection device, including first and second legs, each leg being foldable on itself and including a proximal region. The piston rod is capable of transitioning from a folded position to an unfolded position, and includes a mechanism for coupling the proximal regions of the legs when the piston rod is in the unfolded position. The invention also relates to a kit which includes the piston rod.

Abstract: A cannula (1) for dispensing fluid products, particularly for vaginal and rectal applications, comprises: a tubular body (2) for containing a fluid product (P), having a first extremity (2a), at which a dispenser opening (3) is formed, and a second open extremity (2b), opposed to the first extremity (2a). A cover cap (4) is fitted onto the tubular body (2) to close the dispenser opening (3). A closing body (5) associated with the tubular body (2) closes the second extremity (2b). The closing body comprises a first element (6) and a second element (7) made in a single body piece and joined along tearable connection means (8, 9, 10). The second element (7) removable by tearing off the first element (6) to act as a anti-tampering seal. The first element (6) is a cylinder partially insertable through the second extremity (2b) to function as a sliding piston inside the tubular body (2) once the second element (7) has been torn off.

Abstract: A step-design cannula and delivery system for chronic delivery of therapeutic substances into the brain using convention-enhanced delivery of therapeutic substances and which effectively prevents reflux in vivo and maximizes distribution in the brain.

Abstract: An I.V. flush syringe assembly includes a barrel having an inside surface defining a chamber for retaining fluid, an open proximal end and a distal end with a passageway therethrough in fluid communication with the chamber. An elongate plunger having a proximal end, a distal end and a flexible stopper is slidably positioned in fluid-tight engagement with the inside surface of the barrel for drawing fluid into and out of the chamber by movement of the stopper relative to the barrel. The barrel includes anti-reflux structure for holding said stopper in a partially deflected position after has been delivered from the chamber and the stopper is being force against the distal end of the chamber.