Abstract: A prosthesis (14) that is useful as an anti-reflux device or an anti-obesity device within a gastro-intestinal tract of a living organism, such as a human, comprises an elastic portion including a helical elastic spring (15) embedded in a biocompatible material.
Abstract: This drug delivery device delivers a drug between a syringe barrel and a drug container, and, by enveloping the entire the drug container used in drug delivery, prevents exposure to hazardous drugs adhering to the drug container. This drug delivery device includes: a first member connected to the drug container on the side of a stopper; a second member connected to the first member and to the syringe barrel; and a third member connected to the first member and covering the drug container in a sealed state. The first member has a first hollow needle member and a drug container holder, and the second member has a second hollow needle member. The third member has an opening portion, a bottom surface portion where the drug container is stably mounted, and a flexible member which is connected to the opening portion and the bottom surface portion.
Abstract: Medical dressings and medical dressing kits that can be used to proved positive pressure wound therapy. The medical dressings include one or more normally-closed valves. The medical dressing kits may further include fittings.
Type:
Grant
Filed:
August 31, 2012
Date of Patent:
February 7, 2017
Inventors:
Matthew T. Scholz, Patricia A. Eull, Kenneth A. Peterson, Tony J. Kaufman
Abstract: A plug for use in a passage or conduit of a human body is provided. The plug includes a plug body with a first end and a second end. The plug body has a protrusion on an exterior wall. The plug also includes an attaching member at the first end to attach the plug to the passage or conduit. The plug further includes an axial retention tube within the plug body. The plug further includes a reservoir. The reservoir connects to the retention tube at a third end thereof. The reservoir and the retention tube are configured to regulate the flow of fluid in the passage or conduit.
Type:
Grant
Filed:
June 3, 2013
Date of Patent:
February 7, 2017
Assignee:
HANGZHOU LIUCHA PHARMACEUTICAL LTD.
Inventors:
Chaoyang Hong, Chenglong Wu, Xufeng Lin
Abstract: A distal perfusion sheath (DPS) is provided for cases where blood perfusion is needed for downstream arteries (distal) to the insertion point of the DPS within the target artery. The ability to provide distal perfusion with the DPS allows the DPS to be positioned in the target artery for long periods without causing lack of blood flow (ischemia) to an extremity that the target artery supplies. In embodiments, the DPS can still be used for surgical arterial access while allowing blood flow downstream.
Abstract: According to some embodiments, a system may treat blood outside the body of a patient. The system may include one or more pumps configured to draw blood from a patient into a fluid flow path at a rate, for example, of 5-7 liters per minute. The system may include one or more heat exchangers coupled to the fluid flow path and configured to heat the blood, for example, to a temperature above 42 degrees Celsius and below 43.2 degrees Celsius.
Abstract: The present disclosure relates generally to prosthetic devices for use in restricting food and caloric intake into the stomach and of absorption of the food components in the stomach and small intestine. The system includes an elongated bariatric sleeve having a normally superior or upper proximal end and a normally inferior or lower distal end. An elongated lumen support member is positioned within the first lumen in contacting relation with the first membrane for maintaining the first lumen in an open position. A proximal anchor ring with a central aperture and a catheter channel is connected to the proximal end of the sleeve to the collar member. The anchor is inflatable or expandable memory material for anchoring the sleeve in superior relation to a pyloric valve of the patient's stomach. An anchor weight is connected to the distal end of the first flexible tube.
Type:
Grant
Filed:
March 17, 2014
Date of Patent:
January 31, 2017
Assignee:
EZ-Off Weight Loss, LLC
Inventors:
Mary Pattison, Charles Phillip Pattison, Stephen J. Lowry, Mark A. Molos
Abstract: A method of delivering a medicament to a limb of a patient body includes isolating a circulatory system of the limb from a circulatory system of the patient body, wherein the limb circulatory system is substantially all limb arteries and substantially all limb veins located between an isolation region and an end of the limb. A perfusion catheter is inserted into a limb artery in an antegrade position, while a collection catheter is inserted into a limb vein in a retrograde position. The blood flow of the limb circulatory system is then circulated by collecting the blood flow with the collection catheter and delivering the blood flow with the perfusion catheter. A medicament is perfused into the limb circulatory system with the perfusion catheter.
Abstract: Bubble traps for removing bubbles from a stream of liquid and flexible containers comprising such bubble traps are disclosed. The bubble trap includes a containment chamber fluidly coupled to an outlet conduit. At least one grate is disposed between the containment chamber and the outlet conduit. The at least one grate includes a plurality of grate inlets formed in a grate wall and fluidly coupled to the outlet conduit with a plurality of grate conduits such that the containment chamber is fluidly coupled to the outlet conduit. The grate traps bubbles entrained in the stream of liquid flowing from the containment chamber to the outlet conduit in the containment chamber when the bubbles are greater than or equal to a diameter of the grate inlets.
Type:
Grant
Filed:
May 9, 2014
Date of Patent:
January 31, 2017
Assignee:
Roche Diagnostics International AG
Inventors:
Christoph Huwiler, Florian Kuhni, Andreas Geipel
Abstract: A system and method for increasing the speed of blood and the wall shear stress in a peripheral artery or peripheral vein to a sufficient level and for a sufficient period of time to result in a persistent increase in the overall diameter and lumen diameter of the artery or vein is provided. The method includes systems and methods to effect the movement of blood at the desired rate and in the desired direction. The movement of blood is monitored and adjusted, as necessary, to maintain the desired blood speed and wall shear stress in the peripheral artery or vein in order to optimize the rate and extent of persistent diameter increase of the peripheral artery or peripheral vein.
Abstract: Provided are a device and method for using bilirubin photoisomerization to reduce bilirubin interference with laboratory blood tests for other chemical analytes.
Abstract: An extracorporeal blood cooling or heating circuit includes an intravenous catheter for withdrawing a patients blood coupled to a combined pump/heat exchanger device. One or more sensors are provided upstream and/or downstream of the pump/heat exchanger device for measuring pressure, temperature, fluid flow, blood oxygenation, and other parameters. A controller is operatively coupled to the pump/heat exchanger device and the one or more sensors to control the speed of the pump inside the pump/heat exchanger device and regulate the blood temperature by controlling the operation of the heat exchanger. The combined pump/heat exchanger device includes a housing having at least one inlet and at least one outlet, a pump portion defining a blood circuit inside the housing, and a heat exchanger portion contained within the housing for selectively heating or cooling the blood.
Abstract: A flow reversing device for performing blood treatment can include a flow reversing actuator. The flow reversing actuator can receive and engage a disposable tubing set with multiple branches that form forward and reverse blood flow paths respectively when blood the flow reversing actuator is selectively changed between forward and reverse configurations. The shape of the tubing can be such that during forward operation, dead regions of non-flowing blood are defined. The flow reversing actuator can have a controller configured to operate generally in forward mode. At first times, the controller can cause the flow reversing actuator to clear the dead regions. At second times, the controller can cause the flow reversing actuator to test for leaks by reversing the flow of blood for a period of time sufficient to cause air to be drawn into the tubing set and conveyed to an air sensor.
Abstract: This invention provides an apparatus and methods to consistently separate and concentrate selected blood components. The system includes, e.g., a computerized fluid handling system to transfer blood components between a centrifugal blood separation disc, containers and a concentrator.
Type:
Grant
Filed:
February 4, 2015
Date of Patent:
December 27, 2016
Assignee:
Biomet Biologics, LLC
Inventors:
Douglas M. Arm, Michael Ponticiello, Surinder Mathur, Andrew G. Hood
Abstract: The application describes innovative designs for components of a drug transfer apparatus that overcome problems encountered in daily use of prior art apparatuses. Specifically described are components configured to prevent liquid from entering the air chamber of syringes coupled to the apparatus and to prevent tearing of the rubber stopper of drug vials when they are attached to the apparatus.
Abstract: The present invention relates to a device for draining lymph into vein, which comprises: a storage chamber including a chamber wall, wherein a storage space formed by the chamber wall, and at least one first opening and a second opening are formed on the chamber wall; at least one osmosis membrane disposed at the first opening so that lymph can penetrate into the storage space, wherein the osmosis membrane is made of negative charged polymer molecules; a first conduit, of which one end connects to the storage space, and the other end connects with a vein so that the space can connect with the vein; and a pump provided in the storage chamber, wherein a negative pressure in the storage space is generated by the pump to drain lymph into the vein.
Abstract: Methods for the subungual treatment of diseases or disorders of the nail unit including infections, especially fungal infections, and nail psoriasis involving the toenails and fingernails are described. The methods provide a technique for placement of a drug-containing composition subungually with reduced risk of hematoma formation and improved patient comfort.
Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
Type:
Grant
Filed:
June 25, 2012
Date of Patent:
November 22, 2016
Assignees:
CYTOPHERX, INC., THE REGENTS OF THE UNIVERSITY OF MICHIGAN
Abstract: A liquid transfer connector comprises an enclosure holding a transfer needle and an exhaust needle. A container of donor liquid may be attached to an inlet end of the transfer needle and a container holding a recipient liquid may be attached to an outlet end of the transfer needle and an inlet end of an exhaust needle. The exhaust needle has an outlet end within the connector which releases displaced fluid into an absorbent mass which sequesters the fluid to prevent leakage.
Type:
Grant
Filed:
November 14, 2011
Date of Patent:
November 15, 2016
Assignee:
ONPHARMA, INC.
Inventors:
Matthew J. Stepovich, Randy Kesten, Jeff Zalewski
Abstract: The present invention relates to a medical device connector for connecting a piercing device (3), with a vial (2) comprising a base member. A plurality of grip members (50), each grip member (50) comprising a distal end (D) and a proximal end (P) and each comprising a wedge portion (61) adapted to temporarily or permanently lock the medical device connector (1) to the vial (2). The base member (30) further comprises a plurality of flanges (40), wherein the proximal ends (P) of the grip members (50) are arranged to the flanges (41, 40). The flanges (40) extend substantially out from the periphery of the base member (30) in a direction substantially perpendicular to the direction of the grip members, wherein the space formed between the flanges (40) of the base member (30) forms at least one grip portion.