Patents Examined by Lewis Gotts
  • Polythiocarbamate monomers
    Patent number: 3996257
    Abstract: The invention disclosed is directed to new curable liquid polyene-polythiol compounds containing particular polar groups, at least one unsaturated carbon-to-carbon bond disposed at a terminal position on a main or pendant chain of the molecule and at least one terminally disposed thiol group, with the sum of the unsaturated bonds and thiol groups per polyene-polythiol molecule being at least 3. Upon curling in the presence of a free radical generator such as actinic radiation, the polar polyene-polythiol compounds form solid elastomeric and rigid products which are useful in a variety of applications including coatings, adhesives, sealants and molded articles.
    Type: Grant
    Filed: April 16, 1976
    Date of Patent: December 7, 1976
    Assignee: W. R. Grace & Co.
    Inventor: Donald W. Larsen
  • Alcohol-ether substituted tetrahalo benzonitriles
    Patent number: 3996258
    Abstract: Covers compounds of the formula ##STR1## where R is selected from the group consisting of cyano, nitro and lower alkyl sulfone, X is halo, and R.sub.1 is --CH.sub.2 CH.sub.2 O--.sub.y where y is 1-3 or R.sub.2 O where R.sub.2 is a straight or branched chain alkylene radical containing 2-6 carbon atoms. Also covers a method of preparing said above compounds by reacting ##STR2## with OHR.sub.1 H, where R, X, and R.sub.1 have a significance as above for sufficient time to produce the desired compound. These alcohol-ether substituted aromatics have biological activity and are also useful as chemical intermediates.
    Type: Grant
    Filed: September 2, 1975
    Date of Patent: December 7, 1976
    Assignee: Texaco Development Corporation
    Inventor: Lewis Watts
  • Preparation of dimethylsulfoxide by liquid phase reaction of dimethysulfide and hydrogen peroxide
    Patent number: 3996295
    Abstract: Dimethylsulfoxide is prepared by a method which comprises adding separately dimethylsulfide and an aqueous solution of about 30 to 60 percent by weight hydrogen peroxide to a stirred aqueous liquid reaction medium under an atmosphere of inert gas, said reaction medium containing sufficient dimethylsulfoxide to solubilize the dimethylsulfide.Dimethylsulfoxide has many known uses, particularly as a solvent in spinning polymers, extracting hydrocarbons and the like.
    Type: Grant
    Filed: July 7, 1975
    Date of Patent: December 7, 1976
    Assignee: Produits Chimiques Ugine Kuhlmann
    Inventor: Andre Goeb
  • 2-Hydroxymethyl indole compounds and blood sugar lowering compositions
    Patent number: 3996241
    Abstract: New indole derivatives of the formula ##STR1## wherein R.sub.1 and R.sub.2, which may be the same or different, are hydrogen or halogen or lower alkyl or, taken together, represent a --CH=CH-CH=CH- bridge, with the proviso that R.sub.1 and R.sub.2 are not both hydrogen, and wherein, when R.sub.2 is halogen or alkyl, R.sub.1 can also be alkoxy;Are outstandingly effective in blood sugar lowering action in mammals.
    Type: Grant
    Filed: October 22, 1974
    Date of Patent: December 7, 1976
    Assignee: Boehringer Mannheim G.m.b.H.
    Inventors: Ruth Heerdt, Manfred Hubner, Felix Helmut Schmidt, Kurt Stach
  • Cyanopolyhaloanilines
    Patent number: 3996261
    Abstract: Novel polyhalo, N-substituted aniline compounds are prepared which have the following structural formula: ##STR1## where R is selected from the group consisting of cyano, nitro, and alkyl sulfone, X is halo and Z represents a radical as follows: ##STR2## where R' and R" are hydrogen or lower alkyl, X is a number ranging from 1 to 5, and Y is 0-3. These compounds are prepared by reacting a polyhalo aromatic compound having the formula ##STR3## where X and R have a significance as just discussed with an appropriate polyamino reactant or aminohydroxy compound which additionally may contain either linkages. These new compounds have biological activity and are also useful as chemical intermediates.
    Type: Grant
    Filed: November 6, 1975
    Date of Patent: December 7, 1976
    Assignee: Texaco Development Corporation
    Inventors: Lewis W. Watts, Jr., Philip H. Moss
  • 2,3-Dihydro-1H-dibenz[e,g]isoindole compounds
    Patent number: 3996373
    Abstract: 2,3-Dihydro-1H-dibenz[e,g]isoindoles substituted in the 2-position by a lower alkyl or a lower alkenyl, or a lower haloalkyl, or a free or an esterified or etherified lower hydroxyalkyl, or a lower oxoalkyl, or a free or an esterified lower carboxyalkyl group, and therapeutically usable salts thereof, such compounds having an antagonistic action against reserpine as well as against tetrabenazine such pharmacological properties characterizing these new compounds as antidepressants.
    Type: Grant
    Filed: March 27, 1975
    Date of Patent: December 7, 1976
    Assignee: Ciba-Geigy Corporation
    Inventor: Hans Blattner
  • .alpha.-Bromo-pivaloyl toluenes
    Patent number: 3996286
    Abstract: Acyl substituted phenyl alkanoic acids, e.g. p-pivaloyl phenyl acetic acid, are prepared by hydrolyzing p-pivaloyl phenyl acetonitriles and are useful as hypolipidemic agents.
    Type: Grant
    Filed: September 18, 1975
    Date of Patent: December 7, 1976
    Assignee: Sandoz, Inc.
    Inventors: William J. Houlihan, Jeffrey Nadelson
  • Process for the production of polyisocyanates of isocyanurate structure
    Patent number: 3996223
    Abstract: Soluble polyisocyanates of isocyanurate structure are produced by heating polyisocyanates in the presence of Mannich bases and carbamic acid esters of isocyanates and secondary alcohols. When such a process is used, the polymerization reactions begin without incubation times and the catalysts need not be inactivated by introducing additives because they deactivate themselves at high temperatures.
    Type: Grant
    Filed: October 28, 1975
    Date of Patent: December 7, 1976
    Assignee: Bayer Aktiengesellschaft
    Inventors: Pramod Gupta, Roland Nast, Erwin Windemuth
  • Isoindole derivatives as appetite suppressants
    Patent number: 3996374
    Abstract: Isoindole derivatives of the formula ##STR1## wherein R.sub.1 -R.sub.6, A and Z are as hereinafter described. The isoindole derivatives are useful as appetite suppressants.
    Type: Grant
    Filed: November 20, 1975
    Date of Patent: December 7, 1976
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Roland Jaunin
  • Increasing sucrose content of sugar cane employing N-phenylsulfonamido-N-phosphonomethyl glycine and certain derivatives thereof
    Patent number: 3996040
    Abstract: N-phenylsulfonamido-N-phosphonomethyl glycine and certain derivatives thereof have been found to be useful in the treatment of sugarcane plants to increase their sucrose content.
    Type: Grant
    Filed: June 27, 1975
    Date of Patent: December 7, 1976
    Assignee: Monsanto Company
    Inventor: John E. Franz
  • Synergistic herbicidal compositions
    Patent number: 3996042
    Abstract: Synergistic herbicidal compositions are provided, containing as active ingredients: (1) 3-(benzthiazol-2-yl)-1,3-dimethyl-urea of the formula ##STR1## and (2) 3-(5-n-butylsulphonyl-1,3,4-thiadiazol-2-yl)-1,3-dimethyl-urea of the formula ##STR2## alone or in admixture with a solid or liquid or liquefied gaseous diluent or carrier.
    Type: Grant
    Filed: January 31, 1975
    Date of Patent: December 7, 1976
    Assignee: Bayer Aktiengesellschaft
    Inventors: Herbert Goeldner, Robert Rudolf Schmidt, Carl Metzger
  • Triazine--antidote compositions and methods of use for cotton
    Patent number: 3996043
    Abstract: Herbicidal compositions comprising an active herbicidal compound of the triazine class selected from the group consisting of 2-chloro-4-ethylamino-6-isopropylamino-s-triazine and 2-(4-chloro-6-ethylamino-s-triazin-2-yl-amino)-2-methylpropionitrile, and antidote therefor, and methods of use; the antidote compound corresponds to N-phenylphthalamic acids having the formula ##STR1## in which R is tetrahydromonophthaloyl, halomonophthaloyl in which halo is chlorine or bromine from 1 to 4, inclusive, or monophthaloyl; R' is hydrogen or fluorine.
    Type: Grant
    Filed: January 23, 1976
    Date of Patent: December 7, 1976
    Assignee: Stauffer Chemical Company
    Inventor: Ferenc M. Pallos
  • Dentifrice
    Patent number: 3995024
    Abstract: Dentifrice compositions containing a water-soluble anionic cellulose derivative and stable against syneresis due to its content of a water-soluble salt of a hydroxybenzoate ester and a water-swellable clay of natural or synthetic origin. The salt is preferably a sodium lower alkyl p-hydroxybenzoate.
    Type: Grant
    Filed: March 20, 1975
    Date of Patent: November 30, 1976
    Assignee: Beecham Group Limited
    Inventors: Brian Rae Hawking, Kenneth William Hetherington
  • Derivatives of certain geranyl phenyl ethers
    Patent number: 3994981
    Abstract: Compounds having the formula ##SPC1##In which R is hydrogen, lower alkyl, lower alkenyl, lower alkoxy, halogen, nitro; or lower alkylthio; X is chlorine or bromine; A and B are each hydrogen, together form an epoxide link or together form a bond; the use of these compounds in controlling insects; and a method of preparing these compounds.
    Type: Grant
    Filed: July 5, 1973
    Date of Patent: November 30, 1976
    Assignee: Stauffer Chemical Company
    Inventors: Ferenc M. Pallos, Chien K. Tseng
  • Polyoxyalkylene fluoroalkyltrimellitates
    Patent number: 3994951
    Abstract: Novel polyoxyalkylene fluoroalkyltrimellitate compounds are disclosed that are useful for improving the soil release properties of textiles. These compounds may be conveniently prepared by reacting a fluorinated alkyl thiol or amine with trimellitic anhydride monoacid chloride to form a fluorinated trimellitic anhydride intermediate product which is then reacted with a polyoxyalkylene derivative.
    Type: Grant
    Filed: July 17, 1975
    Date of Patent: November 30, 1976
    Assignee: Pennwalt Corporation
    Inventor: Stanley Robert Sandler
  • Process for the manufacture of peptides containing cystine
    Patent number: 3994871
    Abstract: Process for the manufacture of peptides which contain more than one disulphide bond characterized in that in one or two aminoacid sequences containing cysteine, in which disulphide bonds are to be produced, two cysteine radicals which are to be linked are protected by a mercapto-protective group R.sub.1 of the aralkyl type, two further cysteine radicals are protected by an acylaminomethyl group R.sub.2, the protective groups R.sub.1 are removed by treatment with iodine in the presence of a polyhalogenated lower aliphatic hydroxy compound or oxo compound, or a corresponding lower alkanoic acid lower alkyl ester, at the same time forming the disulphide bond between these cysteine radicals, which are protected by R.sub.1, and at any desired point after removal of the polyhalogenated compound the second disulphide bridge is formed in the usual manner.
    Type: Grant
    Filed: May 20, 1974
    Date of Patent: November 30, 1976
    Assignee: Ciba-Geigy Corporation
    Inventors: Bruno Kamber, Peter Sieber, Bernhard Riniker, Albert Hartmann, Werner Rittel
  • Process for preparing substituted glycines
    Patent number: 3994954
    Abstract: A new process is disclosed for the preparation of N-acyl-.alpha.-aromatic and N-acyl-.alpha.-heteroaromatic glycines by reaction of an .alpha.-ester or ether of an N-acylglycine ester or acid with an aromatic or heteroaromatic compound. Also disclosed are new intermediates for preparing N-acyl-.alpha.-aromatic and N-acyl-.alpha.-heteroaromatic glycines.
    Type: Grant
    Filed: June 24, 1975
    Date of Patent: November 30, 1976
    Assignee: SmithKline Corporation
    Inventors: John G. Gleason, Kenneth G. Holden, Nelson C. F. Yim
  • Vanillin as ripener for sugarcane
    Patent number: 3994715
    Abstract: Sucrose yield of sugarcane is increased by treating the cane crop a few weeks prior to harvest with a ripening agent comprising a hydroxy alkoxy substituted benzaldehyde or acetophephenone, such as vanillin, ethyl vanillin or acetovanillone, or with mixtures comprising one or more such compounds.
    Type: Grant
    Filed: April 17, 1975
    Date of Patent: November 30, 1976
    Assignee: Hawaiian Sugar Planters' Association
    Inventor: Louis G. Nickell
  • Ripening of sugarcane by use of certain monosubstituted benzoic acids
    Patent number: 3994712
    Abstract: Sucrose yield of sugarcane is increased by treating sugarcane a few weeks prior to harvest with a monosubstituted benzoic acid sugarcane ripening agent selected from the group consisting of 2-chlorobenzoic acid, 3-hydroxybenzoic acid, 3-cyanobenzoic acid and 4-methoxybenzoic acid and mixtures thereof.
    Type: Grant
    Filed: June 6, 1975
    Date of Patent: November 30, 1976
    Assignee: Hawaiian Sugar Planters' Association
    Inventor: Louis G. Nickell
  • Xanthate-Lewis acid complexes
    Patent number: 3994950
    Abstract: Xanthate esters of the form: ##EQU1## where R is an alkyl function having at least one H in a position alpha to the R - O bond, (C).sub.n is a linear alkyl function either substituted or unsubstituted, with n = 1 - 3, X has a basicity greater than the >C = S function and comprises a C or S containing functional group having at least one double or triple bond to a hetero atom, the functional group being connected to (C).sub.n through C or S; are reacted with Lewis acids, either neat or in non-protonic non-aqueous solvents, to yield novel Lewis acid complexes of the esters. The Lewis acid -- xanthate ester complex is decomposed by admixture with water or a protonic non-aqueous solvent, e.g. methanol, ethanol, etc., glycol, cellosolve, liquid ammonia, lower alkyl primary or secondary amines, aniline, etc., to yield an unsaturated derivative of R.
    Type: Grant
    Filed: December 8, 1975
    Date of Patent: November 30, 1976
    Assignee: Tee-Pak, Inc.
    Inventors: Noel I. Burke, Douglas J. Bridgeford, Albin F. Turbak