Abstract: This invention relates to a dentifrice comprising (i) at least one source of ionic tin; and (ii) an antibacterial system comprising caprylyl glycol together with 3-phenyl-1-propanol, phenethyl salicylate, or both 3-phenyl-1-propanol and phenethyl salicylate, as well as to methods of using and of making these compositions.

Abstract: Disclosed herein is mucin-coated silica, compositions comprising the same, and methods of promoting the aggregation and/or clearance of oral bacteria using such compositions.

Abstract: Oral compositions containing a carrier, a cationic antimicrobial compound, and a silica and/or silicate material are disclosed. These compositions can provide a controlled release of the antimicrobial compound.

Abstract: Provided is a pumping type toothpaste product including a toothpaste composition. The toothpaste composition includes a polishing agent, and thus prevents the piston of a pumping type container from being worn by the polishing agent contained in the toothpaste composition so that the contents of the container may be ejected out smoothly. Also provided is a gel-like toothpaste composition having excellent viscosity retentivity. Further, provided is an oral composition showing high elasticity even at low viscosity, undergoing little change in viscosity with time and having significantly improved shape retentivity, flowability and dispersion stability through the synergic effect of xanthan gum and a thickening polymer.

Abstract: Anhydrous oral care compositions and methods for making and using the same are described herein. The anhydrous oral care compositions may include an orally acceptable vehicle, a peroxide whitening agent, and an abrasive system. The abrasive system may include at least one abrasive having a pellicle cleaning ratio (PCR) greater than or equal to 100.

Abstract: The present invention discloses topical compositions comprising at least one statin as the main active compound for primary prevention or treatment of periodontal disease, for complementing standard treatment of periodontal disease, and for bone regeneration. The topical compositions are formulated for example, but not limited to, as toothpaste, mouthwash, tablets to dissolve in the mouth, elements or devices for intraoral slow-release of statins, dental floss, gel for being applied in dental trays, concentrated gel for irrigation of periodontal pockets, fluid (for example in blisters), powder, powder or liquid for preparing a solution, and gel. The present invention also discloses method for primary prevention or treatment of periodontal disease, for complementing standard treatment of periodontal disease, and for bone regeneration, comprising administering the topical compositions in the different formulations to a subject in need thereof.

Abstract: The present invention relates to improved complexes of amorphous calcium phosphate and/or amorphous calcium fluoride phosphate stabilised by phosphopeptides/phosphoproteins by addition of stannous ions. These complexes have anticariogenic properties useful to protect tooth structures as they remineralize (repair) early stages of dental caries and have other dental/medical applications (including anti-calculus, anti-erosion/corrosion and anti-dentinal hypersensitivity). Methods of making the complexes of the invention and of treatment or prevention of various dental conditions including dental caries, dental calculus, dental erosion/corrosion and dental hypersensitivity are also provided.

Abstract: A dentifrice composition comprises a toothpaste carrier having a pH of about 7 to about 10 and a calcium ion source and a fluoride ion source wherein the calcium ion source is unencapsulated and the fluoride ion source is encapsulated or coated in a coating impermeable to the toothpaste carrier. The coating degrades to release fluoride ions when mechanically agitated by a toothbrush in an oral cavity surface. In a second embodiment, the dentifrice composition comprises an aqueous toothpaste carrier having a pH of about 7 to about 10 with an unencapsulated calcium ion source and a fluoride ion source having a pH of between 3 to less than 7 wherein the fluoride ion source is encapsulated in a first (or inner) impermeable coating adapted to degrade to release the fluoride ions in the presence of a toothpaste carrier.

Abstract: A dental product in the form of a solid includes a mineral source. The mineral source includes a source or sources of calcium ions, phosphate ions or both calcium ions and phosphate ions. The dental product also includes a salt of carbonic acid, an acidifying agent and xylitol. The acidifying agent includes at least citric acid and malic acid, wherein the citric acid and malic acid are present in a weight ratio of from 4:1 to 1:1.

Abstract: Oral care compositions having polyethylene glycol are more phase stable, particularly with certain flavorants that have a specified range of Dielectric Constant and/or water number and/or C log P value.

Abstract: A self-foaming composition for a topical application is described. The composition can include a medium which is cosmetically- or pharmaceutically-compatible with a topical application, and clobetasol propionate. The composition can include a small quantity of foaming surfactants. The composition includes: at least one intermediate composition B including a gas-generating agent; at least one intermediate composition A including an agent for activating the gas-generating agent; and clobetasol propionate being present in at least one of the intermediate compositions A and B. Also described, is a kit or a single container including a plurality of compartments including such a composition.

Abstract: The present invention relates to oral care compositions and to method of maintaining oral health. The oral care composition of the present invention comprises at least one carbon dioxide source, at least one acid source, at least one abrasive and one or more pharmaceutically acceptable excipients.

Abstract: Provided are methods of detecting tooth stain prevention and/or removal comprising the steps of providing pellicle-coated hydroxyapatite particles, contacting the particles with a first solution and then a second solution, wherein the first solution is either a test solution or a stain solution and the second solution is the other of said test solution or stain solution, separating from the resulting particles a liquid comprising stain introduced in the contacting step b), and measuring the UV-Vis absorbance of the separated liquid to determine the amount of stain in the liquid.

Abstract: A dentifrice composition having a low water phase comprising effective amounts of polyphosphate and ionic active ingredients.

Abstract: Described herein are oral care compositions comprising a surfactant system; a structuring agent, and a lipophilic agent; and methods of making and using the same.

Abstract: A dentifrice composition having a low water phase comprising effective amounts of polyphosphate and ionic active ingredients.

Abstract: Acidic oral compositions having calcium contents and effective pH-values in the area indicated by grey-tone in FIG. 2 are non-erosive in saliva and capable of stimulating saliva production, even in “dry mouth” patients. A new multi-step test method for determining erosive potential in saliva has been used for identifying the compositions.

Abstract: A dentifrice, such as toothpaste, containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions, for use against erosive tooth demineralization, and kits containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions, wherein one of the two active agents is comprised in a dentifrice, are described. The dentifrice in the form of toothpaste may furthermore comprise dissolved tin, in particular stannous ions. Toothpastes containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions are tested in the treatment or prevention of erosive tooth demineralisation caused by citric acid.

Abstract: Provided is a pumping type toothpaste product including a toothpaste composition. The toothpaste composition includes a polishing agent, and thus prevents the piston of a pumping type container from being worn by the polishing agent contained in the toothpaste composition so that the contents of the container may be ejected out smoothly. Also provided is a gel-like toothpaste composition having excellent viscosity retentivity. Further, provided is an oral composition showing high elasticity even at low viscosity, undergoing little change in viscosity with time and having significantly improved shape retentivity, flowability and dispersion stability through the synergic effect of xanthan gum and a thickening polymer.

Abstract: A dental bleaching device may include a backing material made of a polymeric wax mixture, and a dental composition in contact with the backing material. The dental composition may include a thickening agent and a peroxide bleaching agent. The dental composition may be a gelatinous compound having physical deformation properties that allow the dental composition to bend and conform to a shape of a container into which the dental composition is placed, but the dental composition will not merge into a second piece of the dental composition when placed in contact with the second piece.