Patents Examined by Liban M Hassan
  • Patent number: 11442258
    Abstract: Optical systems and apparatuses configured for enabling substantially simultaneous observation of a plurality of points in an array from a common reference point. Without the optical systems and apparatuses disclosed herein, less than all of the plurality of points can be observed substantially simultaneously from the common reference point.
    Type: Grant
    Filed: June 23, 2020
    Date of Patent: September 13, 2022
    Assignee: BioFire Defense, LLC
    Inventors: Richard David Abbott, Patrick L. Riley, Zackery Kent Evans, Lyle M. Nay
  • Patent number: 11421195
    Abstract: Provided is a culture device, including: a culture tank (110) configured to store an object liquid that is a culture solution having suspended therein an object; a screen (210) made of a metal, the screen including a main body (212) and a plurality of through holes (214) passing through the main body from a front surface (212a) thereof to a back surface (212b) thereof; a spray portion (220) configured to spray the object liquid stored in the culture tank onto the front surface of the body; an accommodation portion (240) surrounding the back surface of the main body and configured to accommodate the culture solution having passed through the through holes; a UV light irradiation portion (250) arranged in the accommodation portion and configured to radiate UV light; and a return portion (290) configured to return the culture solution in the accommodation portion to the culture tank.
    Type: Grant
    Filed: March 5, 2020
    Date of Patent: August 23, 2022
    Assignee: IHI CORPORATION
    Inventors: Hiroshi Tanaka, Yoshiaki Matsuzawa, Yuko Yoshida, Norimitsu Kaneko, Jun Muto
  • Patent number: 11414697
    Abstract: A reaction container including a transparent base having a first surface having at least one region where recessed portions are formed and recessed from the first surface, and a cover member positioned such that the cover member forms a gap from the first surface inside the region and is welded to the transparent base outside the region. The cover member absorbs infrared light and transmits light having a wavelength within a range of visible light.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: August 16, 2022
    Assignee: TOPPAN PRINTING CO., LTD.
    Inventors: Masahiro Matsukawa, Yoichi Makino, Akihiro Hoshino
  • Patent number: 11414637
    Abstract: A cell culture container includes a container main body comprising a gas-permeable plastic film, and an injection/discharge port. A peripheral portion of the container main body is sealed, and the container main body has a bulging shape on a top surface side of the container main body. A plurality of concave portions serving as cell culture parts are provided on a bottom surface of the container main body.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: August 16, 2022
    Assignee: TOYO SEIKAN GROUP HOLDINGS, LTD.
    Inventors: Satoshi Tanaka, Ryo Suenaga, Takahiko Totani
  • Patent number: 11407969
    Abstract: The present invention relates in part to devices, systems, and methods for the production and characterization of engineered tissue constructs. The devices and methods generate decellularized tissue constructs that can be recellularized using donor cells for high-throughput studies of organ physiology, and/or organ pathology. The devices and methods can be used with the systems to mechanically and electrically stimulate the engineered tissue constructs under culture or physiological conditions to detect and assess the presence and degree of any organ pathologies.
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: August 9, 2022
    Assignee: Yale University
    Inventors: Stuart Campbell, Jonas Schwan, Andrea Kwaczala, Thomas Ryan, Daniel Jacoby, Yibing Qyang, Lorenzo Sewanan, Ronald Ng, Jeffery Alexander Clark
  • Patent number: 11400454
    Abstract: A mobile field-deployable laboratory to more conveniently enable the detecting, sequencing and analyzing of biological agents at the point-of-need. This device enables field operators to go from sample to actionable information in the field without the need for an internet connection or grid-based power. The present mobile laboratory is configured in a footlocker configuration including a plurality of different compartments specifically configured for holding all of the necessary equipment for use in a wide variety of different applications including successfully extracting, amplifying, sequencing and characterizing specific viruses, pathogens and other bacteria directly in the field including an integrated power supply for providing power to the relevant components for up to 72 hours of continuous use without the need for any external power source. The present mobile laboratory includes a deployable workbench area which provides a stable workstation when the footlocker configuration is deployed.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: August 2, 2022
    Assignee: MRIGlobal
    Inventors: Jonathan L. Jacobs, Joseph A. Russell, Jacob R. Aspinwall
  • Patent number: 11400412
    Abstract: A biofilter irrigation system comprises a cylindrical vessel having a central axis, a media bed positioned within the vessel, a spray head system positioned above the media bed, the spray head system comprising a central hub positioned at the central axis of the vessel, at least one arm extending distally from the central hub toward a wall of the vessel and configured to rotate about the central axis, and a plurality of nozzles connected to the at least one arm. The biofilter irrigation system further comprises a fluid outlet positioned below the media bed.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: August 2, 2022
    Assignee: Evoqua Water Technologies LLC
    Inventors: Michael Sumner Murphy, James Paul Harshman, Eric Carl Hansen
  • Patent number: 11359172
    Abstract: A single-use chamber comprising a primary subchamber containing at least one primary component configured to perform an operation comprising at least one of generation and handling of a biological material; and a secondary subchamber containing at least one of a connection to equipment external to the single-use chamber and a secondary component, wherein the external equipment and the secondary component are configured to support the operation of the at least one primary component; wherein the primary subchamber and the secondary subchamber are configured to be connected to each other so that the at least one primary component is operatively coupled to at least one of the connection and the secondary component.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: June 14, 2022
    Assignee: Sartorius Stedim Biotech GmbH
    Inventor: Frank Maggiore
  • Patent number: 11319522
    Abstract: The present application belongs to the technical field of biology. Provided is a photobioreactor used for algae cultivation, said photobioreactor comprising: a reactor main body, a separation unit, and a first aeration device. The reactor main body is a sealed irregular tubular shape, the separation unit is located within the reactor main body, and divides the reactor main body into two spaces, a left space and a right space, and the first aeration device is connected to a bottom portion of the reactor main body. Also provided is an algae cultivation system, comprising the photobioreactor, the second aeration device, and a temperature control system, and being capable of regulating the temperature of an algae solution.
    Type: Grant
    Filed: May 18, 2016
    Date of Patent: May 3, 2022
    Assignee: Zhongzhi He
    Inventors: Bosheng Li, Hang Li
  • Patent number: 11306280
    Abstract: The present application focuses on systems and methods that utilize one or more carbon dioxide (CO2) sorbent substrates and a swing cycle, e.g., a moisture swing cycle, to increase the partial pressure of the CO2 in a gaseous feedstock, which is delivered through a membrane to a bioreactor, such as a membrane carbonation photobioreactor. Such systems and processes offer an effective means for concentrating and capturing CO2 obtained from air and delivering the concentrated CO2 to a photobioreactor through a membrane.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: April 19, 2022
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventors: Bruce Rittmann, Klaus Lackner, Justin Flory, Megha Patel, Allen Wright
  • Patent number: 11306282
    Abstract: A system may include a base assembly having a top and a bottom restable on a surface, with the base assembly comprising at least one trough having an upper opening into a cavity and a trough holder configured to hold the at least one trough. The system may also include a cover assembly mounted on the base assembly and configured to cover the at least one trough in the holder. The cover assembly may comprise a main cover portion including a cover wall extending over the at least one trough, with at least one aperture extending through the main cover portion and being substantially vertically aligned with the cavity of the at least one trough mounted on the base assembly. The cover assembly may also include a disc pressure portion configured to removably insert into the at least one aperture press against a disc positioned at the aperture of the main cover portion to move the disc toward the cavity of the at least one trough.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: April 19, 2022
    Inventor: John L. Sternick
  • Patent number: 11292004
    Abstract: A method for metering and storing liquids by means of a permanently open container (1), wherein: the container (1) comprises a liquid reservoir (11) in which at least one liquid (2) is contained for storage; the container (1) has at least one opening (15) for the metered discharging of the liquid from the liquid reservoir (11); the opening (15) is permanently open; influencing factors affect at least one change in pressure (4) in the container (1); influencing factors render the system formed of the container (1) and liquid (2) unstable; the pressure (4) is detected in at least one location in the container (1); and, subject to at least one detected change in pressure (4), at least one reaction (9) is initiated that is suitable for maintaining the system of the container (1) and liquid (2) in a stable state or for re-establishing this stable state.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: April 5, 2022
    Assignee: Aquila Biolabs GmbH
    Inventors: Konrad Herzog, David Frank, Carsten Presser
  • Patent number: 11286450
    Abstract: A culture system includes a dish and a lid. The dish comprises a base, a sidewall extending from the base, and a track extending outwardly from an outer surface of the sidewall. The lid comprises a central horizontal wall and a recess formed by two sidewalls and a top wall. At least one key extends downwardly from the recess. The sidewall of the dish extends into the recess of the lid, and the key engages the track. The track is shaped so that the lid rises or falls relative to the base of the dish when the lid is rotated relative to the dish.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: March 29, 2022
    Assignee: Oxyrase, Inc.
    Inventors: James C. Copeland, John E. Richey
  • Patent number: 11252956
    Abstract: A container includes a vial, cap, and one or more wireless transponders secured to the cap, the vial or a jacket to store and identify samples of biological material at cryogenic temperatures (e.g., vitrified biological samples), for instance held by cryopreservation storage devices. A specimen holder may be extend from the cap. The vial and/or cap includes ports or vents. A carrier includes a box, thermal shunt, thermal insulation to store and identify arrays of containers that hold cryopreservation storage devices with samples of biological material at cryogenic temperatures. Various apparatus include wireless transponders positioned and oriented to enhance range, and allow interrogation while retained in a carrier. Various apparatus can maintain the biological material at or close to cryogenic temperatures for prolonged period of times after being removed from a cryogenic cooler, and can allow wireless inventorying while maintaining the biological samples at suitably cold temperatures.
    Type: Grant
    Filed: April 6, 2020
    Date of Patent: February 22, 2022
    Assignee: TMRW Life Sciences, Inc.
    Inventors: William Alan Blair, Timothy Alan Sharp
  • Patent number: 11248202
    Abstract: A cell observation device is cell observation device for observing a cell held by a microplate having a well holding a sample including the cell and includes a microplate holder for holding the microplate thereon, an electrical stimulation unit including an electrode pair including a first electrode and a second electrode, and a position controller for controlling a position of the electrical stimulation unit in a state in which the first electrode is disposed closer to the center of the well than the second electrode when the electrode pair is disposed in the well of the microplate. The tip of the first electrode extends more than the tip of the second electrode.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: February 15, 2022
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Natsumi Saito, Taira Ito, Takuji Kataoka
  • Patent number: 11248250
    Abstract: A self-contained biological indicator (“SCBI”) is disclosed. The SCBI may include a first ampule and a second ampule. The first ampule may contain a first volume of a first growth medium, and the second ampule may contain a second volume of a second growth medium. The SCBI is configured such that the first ampule may be broken before the second ampule. The SCBI may be analyzed for changes in fluorescence of the first growth medium. Then, the SCBI may be analyzed for changes in a color of the second growth medium.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: February 15, 2022
    Assignee: ASP GLOBAL MANUFACTURING GMB
    Inventors: Ben Fryer, Yan Fang
  • Patent number: 11231347
    Abstract: A system, methods, and apparatus are described to collect and prepare single cells, nuclei, subcellular components, and biomolecules from specimens including tissues. The system can perform enzymatic and/or physical disruption of the tissue to dissociate it into single-cells or nuclei in suspension or subcellular components including nucleic acids. In some embodiments, the titer of dissociated cells is monitored at intervals and the viability determined. In some embodiments, the processing is adjusted according to the measurements of the titer and viability. In some embodiments, the single-cells or nuclei in suspension are washed and resuspended in the buffer or media of choice. In some embodiments, the conditions are chosen to produce nuclei. In other embodiments, the single-cells or nuclei are purified by affinity paramagnetic bead processing. In some embodiments, matched bulk nucleic acid to the single-cells is produced.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: January 25, 2022
    Assignee: S2 GENOMICS, INC.
    Inventors: Stevan Jovanovich, Frank Zaugg, Kaiwan Chear, Roger McIntosh, Nathan Pereira
  • Patent number: 11208624
    Abstract: A device for centering of petri dishes, where the petri dishes include a bottom container with a lateral surface and a lid with a lid diameter, including an elevator with an elevator axis and an elevator drive, and the conveyor includes concentrically along the elevator axis a frustoconical through-hole tapering downwards, and the elevator drive is built to move a substantially flat plate from a neutral position downwards into a first position, which is reached as soon as the petri dish rests with its weight on the inner surface of the through-hole, and the elevator drive is built to rotate the plate during a movement of the plate from the neutral position into the first position.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: December 28, 2021
    Assignee: CLEVER CULTURE SYSTEMS, AG
    Inventors: Alexander Bohm, Nedim Bogilovic, Wolfgang Stiegmaier
  • Patent number: 11208623
    Abstract: A disposable polymer container for manipulation of small specimens adapted to optimize heat transfer between an external heating element and specimens herein contained. In particular, this invention relates to the field of containers for Assisted Reproductive Technology hereunder In-vitro fertilization (IVF).
    Type: Grant
    Filed: December 17, 2019
    Date of Patent: December 28, 2021
    Assignee: HertART ApS
    Inventors: Henrik Carlheim Dörge, Bjarne Bo Jensen
  • Patent number: 11203735
    Abstract: A system to process a waste food includes a housing; at least one drum enclosed in the housing where the waste food is mixed up and digested by microorganisms or dehydrated; and at least one cleaner incorporated in or on the machine to permit a jet of water to be turned on and off to clean the drum.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: December 21, 2021
    Assignee: Power Knot Inc.
    Inventors: Iain Milnes, Agile Johns