Abstract: The present invention provides hydrochlorofluorocarbons having 3 to 5 carbons atoms, 1 to 2 chlorine atoms, and an OH rate constant from about 8 to about 25 cm.sup.3 /molecule/sec.times.10.sup.-14. The hydrochlorofluorocarbons are useful as solvents and blowing agents.

Abstract: Tetrahydrofurans, tetrahydrothiophenes, pyrrolidines and cyclopentanes are disclosed that reduce the chemotaxis and respiratory burst leading to the formation of damaging oxygen radicals of polymorphonuclear leukocytes during an inflammatory or immune response. It has been determined that 5-lipoxygenase activity, oral availability, and stability in vivo (for example, glucuronidation rate) can vary significantly among the optical isomers of the disclosed compounds.

Abstract: This invention relates to ethylene oxide catalyst for the vapor phase production of ethylene oxide from ethylene and oxygen prepared by impregnating a porous, refractory support having a surface area ranging from about 0.05 to about 10 m.sup.2 /g with a solubilized catalytically effective amount of silver, a solubilized promoting amount of alkali metal, a solubilized promoting amount of rhenium, and a solubilized promoting amount of hafnium metal, wherein the Group IVB metal is provided in the form of Group IVB oxycation-containing salts. The catalyst provide substantial initial activity improvement as well as long term selectivity and activity stability improvement over prior art rhenium promoted catalyst, without any loss of initial selectivity advantage.

Abstract: A benzylpiperidine compound of formula I ##STR1## in which R.sup.1 is H, Hal or nitro,R.sup.2 is a benzyl group, which is unsubstituted or substituted by Hal on the aromatic portion, in the 2-, 3- or 4-position of the piperidine ring, with the proviso that R.sup.2 is not in the 4-position if X is --CO--, Y and Z are --CH.sub.2 and R.sup.1 is H,R.sup.3 is H or A,X is --O--, --S--, --NH--, --CO-- or --SO.sub.2 --,Y is --CH.sub.2 --, --NH--, --O--, --S--, --NH-- or alternatively --CO-- if X is --CO-- and Z is --NH-- or --NA--,Z is --CH.sub.2 --, --C(A).sub.2-, --CH.sub.2 CH.sub.2 --, --CH.dbd.CH--, --CO--, --NH--, --NA--, --O--, --S-- or a bond,wherein X--Y or Y--Z is not --O--, --S--S--, --NH--O--, --O--NH--, --NH--NH--, --O--S-- or --S--O,A is alkyl having 1-6 C atoms,B is O or both H and OH, i.e.

Abstract: Hydrofluoroalkanes useful as solvents, especially for vapor degreasing and solvent cleaning, are one or many of the following formulae:CHF.sub.2 --X--(CHF).sub.n --X--Ywherein X is selected from the group consisting of CHF, CF.sub.2 and CH.sub.2, Y is CH.sub.3, and n is 0, 1 or 2.

Abstract: 4-Mercaptobenzoylguanidines of the formula I ##STR1## in which A, R.sub.1, R.sub.2 and R.sub.3 have the meanings given, and the physiologically unobjectionable salts thereof exhibit antiarrhythmic properties and are active as inhibitors of the cellular Na.sup.+ /H.sup.+ antiporter.

Abstract: The present invention relates to functionalized ketones and novel processes for synthesizing those ketones. The processes of this invention are especially well suited for synthesizing .alpha.-methyl leaving group functionalized ketones. This invention also relates to processes for using .alpha.-methyl leaving group functionalized ketones to produce other compounds and intermediates useful in those processes.

Abstract: A process for preparing 6, 7, 8, 9-tetrahydro-1H-imidazo?4,5-c!quinolin-4-amines is disclosed. The process involves the reduction of a 1H-imidazo?4,5-c!quinolin-4-amine or of a 6H-imidazo?4,5-c!tetrazolo?1,5-a!quinoline.

Abstract: An oxazolinone derivative compound, represented by the general formula I, shows superior herbicidal activity against, especially, dicotyledonous vegetables. It is effective upon applying both before and after the sprouting of vegetables. It is prepared by condensating an .alpha.-amino acid represented by the general formula II with an acid chloride represented by the general formula III, to give an acyl .alpha.-amino acid represented by the following formula IV: reacting the acyl .alpha.-amino acid with acetic anhydride; and dehydrating the resulting adduct: ##STR1## wherein, R represents a lower alkyl group or a phenyl group containing halogen, lower alkyl or trifluoromethyl group; X represents halogen atom, carbomethoxy group, nitro group, or halogen or trifluoromethyl-substituted phenoxy group, being the same or different from one another; A represents nitrogen or carbon atom; and n is an integer of 1 to 3.

Abstract: A 2-(unsubstituted or substituted) (benzyloxy or phenoxy)-4-substituted-6-(meta-substituted phenoxy)pyridine represented by the formula (I): ##STR1## wherein R represents C.sub.1 -C.sub.4 alkoxy or cyano; each X, which may be identical or different if n is greater than 1, represents a halogen, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 haloalkythio, C.sub.3 -C.sub.5 alkenyloxy, or C.sub.3 -C.sub.5 alkynyloxy;Y represents trifluoromethyl, difluoromethoxy, trifluoromethoxy, or trifluoromethylthio;m represents an integer of 0 or 1; andn represents an integer of 0 to 5, which is useful as a herbicide.

Abstract: Compounds of the formula ##STR1## where R.sub.1, R.sub.2, R.sub.3, and R.sub.4 independently are H or lower alkyl of 1 to 10 carbons; R.sub.5 is lower alkyl of 1 to 10 carbons, fluoro, chloro, bromo, iodo, nitro, or fluoroalkyl having 1 to 10 carbons; m is an integer having the value of 1-4; n is an integer having the value of 0-4; Y is phenyl or a heteroaryl group selected from a group consisting of pyridyl, thienyl, furyl, pyridazinyl, pyrimidinyl, pyrazinyl, thiazolyl and oxazolyl, said Y group being optionally substituted with one or more R.sub.5 group; A is (CH.sub.2).sub.p where p is 0-5, lower branched chain alkyl having 3-6 carbons, cycloalkyl having 3-6 carbons, alkenyl having 2-6 carbons and 1 or 2 double bonds, alkynyl having 2-6 carbons and 1 or 2 triple bonds, and B is hydrogen, COOH or a pharmaceutically acceptable salt thereof, COOR.sub.8, CONR.sub.9 R.sub.10, --CH.sub.2 OH, CH.sub.2 OR.sub.11, CH.sub.2 OCOR.sub.11, CHO, CH(OR.sub.12).sub.2, CHOR.sub.13 O, --COR.sub.7, CR.sub.7 (OR.sub.12).sub.

Abstract: A process is described for the preparation of a compound of formula (IX) from 4-hydroxybutyl 3-pyridyl ketone. The compound of formula (IX) is an intermediate useful in the preparation of (1R,2R)-2-(3-pyridyl)-N-alkyl-tetrahydro-2H-thiopyran-2-carbothioamide 1-oxides which possess useful pharmaceutical properties, for example anti-hypertensive properties.

Abstract: Propylene is converted to propylene oxide in a vapor phase oxidation process employing a silver catalyst supported on an alkaline earth metal carbonate and containing both a potassium salt such as potassium nitrate and a molybdenum promoter. The potassium salt and the molybdenum promoter may be simultaneously supplied by the use of a potassium salt of a molybdenum oxyanion. The efficiency of the process is greatly enhanced through the simultaneous inclusion of carbon dioxide and an organic halide in the feedstream. The feedstream need not contain a nitrogen oxide species such as NO to attain high propylene oxide selectivity.

Abstract: A crystalline molecular sieve having a framework structure isomorphous with zeolite beta and containing Si and Ti, but essentially no framework Al, usefully catalyzes olefin epoxidation wherein hydrogen peroxide is the oxidant.

Abstract: This invention relates to a novel catalyst composition comprising a heteropolyacid and a siliceous support which is in the form of extrudates or pellets and to a process for hydrating olefins to the corresponding alcohols in the vapour phase in the presence of such a catalyst composition. By using the specific catalyst composition described herein it is possible not only to increase the space-time-yield of a process but also to prolong the life thereof thereby reducing the frequency with which the catalyst is changed or replaced on a plant, especially in an olefin hydration process.

Abstract: The present inventions provide manufacturing methods of 1,1,1,2,3-pentafluoropropene characterized by the reaction of removing HF by means of the contact of 1,1,1,2,3,3-hexafluoropropane in the gas state with active carbon or active carbon added with metallic salt. 1,1,1,2,3-pentafluoropropene can be produced from easily available 1,1,1,2,3,3-hexafluoropropane by cost-effective industrial methods at high yields according to these inventions.The inventions also provide manufacturing methods of 1,1,1,2,3-pentafluoropropane characterized by reducing 1,1,1,2,3-pentafluoropropene with hydrogen under the presence of a hydrogenation catalyst consisting of palladium added with one or more of silver, copper, gold, tellurium, zinc, chromium, molybdenum, and thallium or under the presence of a rhodium catalyst. The desired product can be produced at high reactivities and high selectivities according to these inventions.

Abstract: The present invention relates to a compound of the formula: ##STR1## wherein R.sub.1 stands for an optionally esterified or amidated carboxyl group, X stands for an optionally substituted divalent hydrocarbon residue, R.sub.2 stands for hydrogen or an optionally substituted hydrocarbon residue, R.sub.3 stands for an alkyl group which is substituted with a group bonded through O or S(O).sub.n wherein n is 0, 1 or 2, with a proviso that when the partial structural formula: --NH--X--CO-- is leucine residue, R.sub.3 is not 3-hydroxy-3-methylbutyl group nor 4-hydroxy-3-methylbutyl group, or a salt thereof, which is useful as prophylactic and therapeutic agents of bone diseases and as inhibitory agents of thiol protease.

Abstract: A process for producing perfluorocarbons which comprises a step of contacting a hydrofluorocarbon with fluorine gas in a vapor phase at an elevated reaction temperature in a first reaction zone to obtain a gaseous reaction mixture; and a step of introducing the gaseous reaction mixture as a diluent gas into a second reaction zone and contacting the same therein at an elevated reaction temperature with a hydrofluorocarbon fed to the second reaction zone if necessary together with fluorine gas, the hydrofluorocarbon fed to the second reaction zone being different from the hydrofluorocarbon reacted in the first reaction zone.

Abstract: Process for the production of epoxides from olefins and hydrogen peroxide in the presence of a zeolite containing titanium atoms as catalyst, to which neutral- or acid-reactive salts are added before or during the reaction.

Abstract: Fatty alcohols of the formula IR.sup.1 OH (I)wherein R.sup.1 is a saturated or unsaturated, linear or branched aliphatic radical having from about 8 to about 22 carbon atoms are made by an improvement in the process which comprises hydrogenating a fatty acid, a fatty acid methyl ester or a combination thereof to form a fatty alcohol. The improvement comprises removing a head fraction from the fatty acid, the fatty acid methyl ester or the fatty alcohol in such a quantity that the fatty alcohol has an iodine value of from about 20 to about 110 and less than about 4.5% by weight of conjugated compounds.