Patents Examined by Maris R Kessel
  • Patent number: 10436740
    Abstract: A method for manufacturing a sensor element for detecting (i) a gas component in a measuring gas or (ii) a temperature of the measuring gas includes: introducing at least one functional element into at least one slip at least once in such a way that a slip layer is applied to the functional element, the functional element including at least one solid electrolyte and at least one functional layer; sintering the slip layer on the functional element; grinding the slip layer at least in the area of the at least one functional layer; impregnating the slip layer; and thermally treating the impregnated slip layer.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: October 8, 2019
    Assignee: Robert Bosch GmbH
    Inventors: Siegfried Nees, Petra Kuschel, Harry Braun, Jens Schneider
  • Patent number: 10429347
    Abstract: A method of determining a charge of at least one test particle (as herein defined), comprising: applying one of an electric current or a voltage across an aperture connecting two chambers, whereby the chambers are at least partially filled with electrolyte and whereby the at least one test particle is suspended in the electrolyte of at least one of the chambers; measuring a value indicative of the other of the electric current or voltage across the aperture; determining a time interval between a first and a second point in time, the second point in time corresponding to a point in time when the measured current or voltage has reached a specific proportion of the measured current or voltage at the first point in time; and determining the charge of the at least one test particle by: determining a value indicative of an electrical velocity component of a total velocity of at least one calibration particle having a known charge, taking into account that the total velocity of the at least one calibration particle
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: October 1, 2019
    Inventors: Benjamin Mark Glossop, Robert Vogel, Eva Weatherall, Martin David Jones
  • Patent number: 10415143
    Abstract: The present invention provides a method for the production in an electrochemical cell of one or more of graphene, graphite nanoplatelet structures having a thickness of less than 100 nm, and graphane, wherein the cell comprises: (a) a negative electrode which is graphitic; (b) a positive electrode which may be graphitic or another material; and (c) an electrolyte selected from (i) an ionic liquid; (ii) a deep eutectic solvent; and (iii) a solid ionic conductor, optionally further comprising (iv) one or more ionic species, wherein the amount of (i), (ii) or (iii) and (iv) is greater than 50 wt % based on the total weight of the electrolyte; and wherein the electrolyte includes a mixture of different cations; and wherein the method comprises the step of passing a current through the cell to intercalate ions into the graphitic negative electrode so as to exfoliate the graphitic negative electrode.
    Type: Grant
    Filed: August 6, 2014
    Date of Patent: September 17, 2019
    Assignee: The University of Manchester
    Inventors: Robert Angus William Dryfe, Ian Anthony Kinloch, Amr M. Abdelkader
  • Patent number: 10400344
    Abstract: Provided is an electrode assembly for electrolytic processing in an electrolysis cell comprising an electrode blade comprising a metallic hanger bar portion, a first lug for supporting the metallic hanger bar portion on a first power supply bar, an insulating piece connecting the metallic hanger bar portion to the first lug. The electrode assembly also comprises an electrical switch unit controlling electrical current supply between the first lug and the metallic hanger bar based on a control signal transmitted to a terminal of the electrical switch unit, a control unit configured to transmit the control signal to the terminal of the electrical switch unit, and a power storage unit configured to supply power to the control unit, the power storage unit being charged from the first lug and the hanger bar when the electrical switch unit switches off electrical current supply between the first lug and the metallic hanger bar.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: September 3, 2019
    Assignee: OUTOTEC (FINLAND) OY
    Inventors: Duncan Grant, Michael H. Barker, Henri K. Virtanen, Sönke Schmachtel, Ari Rantala, Lauri Nordlund
  • Patent number: 10393701
    Abstract: Microfluidic methods of assaying molecule switching are provided. Aspects of the methods include microfluidically separating a sample containing the molecule of interest and then employing the resultant separation pattern to determine a switching characteristic of the molecule. Also provided are microfluidic devices, as well as systems and kits that include the devices, which find use in practicing embodiments of the methods. The methods, devices, systems and kits find use in a variety of different applications, such as analytical and diagnostic assays.
    Type: Grant
    Filed: September 24, 2013
    Date of Patent: August 27, 2019
    Assignee: The Regents of the University of California
    Inventors: Amy E. Herr, Augusto M. Tentori, Alex J. Hughes
  • Patent number: 10386320
    Abstract: The present invention, in one set of embodiments, provides methods and systems for integrating conducting diamond electrodes into a high power acoustic resonator. More specifically, but not by way of limitation, in certain embodiments of the present invention, diamond electrodes may be integrated into a high power acoustic resonator to provide a robust sensing device that may provide for acoustic cleaning of the electrodes and increasing the rate of mass transport to the diamond electrodes. The diamond electrodes may be used as working, reference or counter electrodes or a combination of two or more of such electrodes. In certain aspects, the high power acoustic resonator may include an acoustic horn for focusing acoustic energy and the diamond electrodes may be coupled with the acoustic horn.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: August 20, 2019
    Inventors: Clive E. Hall, Li Jiang, Timothy G. J. Jones, Andrew Meredith, Nathan S. Lawrence, Markus Pagels
  • Patent number: 10379079
    Abstract: A semiconductor device, comprising a first field effect transistor (FET) connected in series to a second FET, and a third FET connected in series to the first FET and the second FET. The semiconductor device further includes bias circuitry coupled to the first FET and the second FET, and an output conductor coupled to a terminal of the second FET, wherein the output conductor obtains an output signal from the second FET that is independent of the first FET.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: August 13, 2019
    Inventor: Keith G. Fife
  • Patent number: 10379080
    Abstract: Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.
    Type: Grant
    Filed: July 6, 2015
    Date of Patent: August 13, 2019
    Assignee: Robert Bosch GmbH
    Inventors: Christopher Johnson, Sam Kavusi, Nadezda Fomina, Habib Ahmad, Autumn Maruniak, Christoph Lang, Ashwin Raghunathan
  • Patent number: 10365287
    Abstract: Although analysis can be very quickly conducted at a low cost by a method for measuring a biopolymer using a nanopore, the accuracy of distinguishing the individual monopolymers constituting the biopolymer is low. To both ends of a biopolymer through a nanopore, molecules which are larger than the nanopore are attached and then the biopolymer is reciprocated by an external force to thereby perform repeated measurements.
    Type: Grant
    Filed: March 1, 2010
    Date of Patent: July 30, 2019
    Inventors: Tomoyuki Sakai, Takeshi Fujita
  • Patent number: 10359390
    Abstract: A method is disclosed for determining analyte concentration that includes applying a first electrical potential excitation pulse to a body fluid sample in an analyte sensor, and a first current response of the body fluid sample to the first pulse is measured. A second excitation pulse is applied to the body fluid sample in the analyte sensor, and a second current response of the body fluid sample to the second pulse is measured. An analyte level in the body fluid sample is determined by compensating for sources of error based on the first current response to the first pulse.
    Type: Grant
    Filed: June 18, 2013
    Date of Patent: July 23, 2019
    Inventors: David W. Burke, Michael Marquant, Nigel A. Surridge
  • Patent number: 10344324
    Abstract: A technique is provided for controlling biomolecules in a nanodevice. A membrane has two reservoirs at opposing ends of the membrane. A nanochannel is formed in the membrane connecting the two reservoirs. A gate electrode is formed on the membrane such that the gate electrode extends laterally in a region of the nanochannel. A biomolecule is trapped in the nanochannel by applying a first voltage to the gate electrode. In response to trapping the biomolecule, the biomolecule is stretched in the nanochannel by applying a second voltage to the gate electrode. The biomolecule is stretched based on changing from the first voltage to the second voltage applied to the gate electrode.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: July 9, 2019
    Inventors: Binquan Luan, Sung-wook Nam
  • Patent number: 10345256
    Abstract: In a gas sensor where an exhaust gas is introduced into a chamber provided in a gas sensor element so that an oxygen concentration is reduced in a pump cell on the upstream side to detect NOx in the exhaust gas in a sensor cell on the downstream side, the surface of at least one of a solid electrolyte sheet and a shielding sheet that constitute wall surfaces of the chamber has a warped shape which is convex inwardly of the chamber at a position where the pump cell is formed. The warp amount is in the range from 0.10% or higher to 1.38% or lower, and the height in the stacking direction of the diffusion layer is lower than the average height Have in the stacking direction of the chamber at the position where the pump cell is formed.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: July 9, 2019
    Inventors: Kei Sugiura, Yoshiyasu Ando
  • Patent number: 10345255
    Abstract: A sensor system, device, and methods for determining the concentration of an analyte in a sample is described. Input signals including multiple duty cycles of sequential excitation pulses and relaxations are input to the sample. One or more signals output from the sample within 300 ms of the input of an excitation pulse may be correlated with the analyte concentration of the sample to improve the accuracy and/or precision of the analysis. Determining the analyte concentration of the sample from these rapidly measured output values may reduce analysis errors arising from the hematocrit effect, mediator background, and other error sources.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: July 9, 2019
    Inventor: Huan-Ping Wu
  • Patent number: 10338025
    Abstract: A meter is adapted for measuring concentrations of a chemical in a flowing solution. The meter has a barrier that shields a sensor from the high turbulence of the solution flow. One or more membranes can be employed to selectively filter out various ions or other chemicals.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: July 2, 2019
    Inventor: Frederick Quincy Johnson
  • Patent number: 10330636
    Abstract: A gas sensor element including a composite ceramic layer including a plate-shaped insulating portion containing an insulating ceramic and having a through hole formed therein and a plate-shaped electrolyte portion containing a solid electrolyte ceramic and disposed in the through hole; and a first conductor layer extending continuously from a first insulating surface on one side of the insulating portion to a first electrolyte surface of the electrolyte portion facing the same direction as the one side of the insulating portion. The first insulating surface is flush with the first electrolyte surface. The electrolyte portion has, on its first electrolyte surface side, an extension portion extending outward from the through hole so as to overlap the first insulating surface. Further, the thickness of the extension portion decreases toward the outer circumference of the extension portion. Also disclosed is a method of manufacturing the gas sensor element.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: June 25, 2019
    Assignee: NGK SPARK PLUG CO., LTD.
    Inventor: Ai Igarashi
  • Patent number: 10309926
    Abstract: The present invention relates to a device for controlling movement of a fluid sample along a flow path and a corresponding method. The device comprises a working electrode (2) arranged to contact the fluid sample when the fluid sample moves along the flow path, and a reference electrode (3) arranged to contact the fluid sample when the fluid sample moves along the flow path. At least a portion of the reference electrode is arranged abreast of or downstream at least a portion of the working electrode. The present invention is advantageous in that it provides a device wherein a fluid sample may be transported and accurately controlled, with respect to e.g. timing, volumes and flow rates, over greater distances compared to prior art.
    Type: Grant
    Filed: September 3, 2013
    Date of Patent: June 4, 2019
    Assignee: GINOLIS OY
    Inventors: Fredrik Jansson, Magnus Molin
  • Patent number: 10295497
    Abstract: A disposable screen-printed microchip based on an organic membrane sensitive layer is presented. The microchip is highly responsive for the determination of Lead(II). The microchip is composed of a composite sensitive material which comprises carbon nano-tubes “CNTs” and titanium (IV) oxide nano-particles embedded in a PVC membrane which was deposited on the surface of a plastic screen printed micro-electrode using a new methodology. The prepared disposable microchip provides a linear response for Pb2+ ions covering the concentration range of 1×10?6 to 1×10?1 mole L?1 with high sensitivity (49 mV), a long life span (>4 months) and short response time (10 s). The merits offered by the micro-sensor or microchip include small size, simple fabrication, mass production, integration feasibility and cost effectiveness and automation.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: May 21, 2019
    Assignee: King Abdulaziz City for Science and Technology (KACST)
    Inventors: Hassan Abdou Arida, Mohammad Ateeq AlDosari
  • Patent number: 10294507
    Abstract: Disclosed herein is a device that functions as a glucose sensor. The device has a reference electrode; a counter electrode, a working electrode; an electrically conducting membrane; an enzyme layer; a semi-permeable membrane; a first layer of a first hydrogel in operative communication with the working electrode; the first layer of the first hydrogel being operative to store oxygen; wherein the amount of stored oxygen is proportional to the number of freeze-thaw cycles that the hydrogel is subjected to; and a second layer of the second hydrogel. Disclosed too is a method that comprises using periodically biased amperometry towards interrogation of implantable glucose sensors to improve both sensor's sensitivity and linearity while at the same time enable internal calibration against sensor drifts that originate from changes in either electrode activity or membrane permeability as a result of fouling, calcification and/or fibrosis.
    Type: Grant
    Filed: May 27, 2014
    Date of Patent: May 21, 2019
    Inventors: Fotios Papadimitrakopoulos, Santhisagar Vaddiraju
  • Patent number: 10287699
    Abstract: The invention generally relates to sensors, methods of manufacture thereof, methods of use thereof for sensing analytes, such as small molecules and biomolecules, and methods of immobilization. In certain embodiments, the invention provides a multi-analyte sensor. The multi-analyte sensor includes a plurality of sensing electrodes. Each sensing electrode is functionalized with a different molecule (e.g., biomolecule), at least two of the sensing electrodes are spaced apart prior to and after functionalization by 100 ?m or less, and there is no cross-talk between the plurality of sensing electrodes.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: May 14, 2019
    Assignee: Purdue Research Foundation
    Inventors: Rajtarun Madangopal, Jenna L. Rickus
  • Patent number: 10288576
    Abstract: A device for sensing a property of a fluid comprising a first substrate having formed thereon a sensor configured in use to come into contact with a fluid in order to sense a property of the fluid, and a wireless transmitter for transmitting data over a wireless data link and a second substrate having formed thereon a wireless receiver for receiving data transmitted over said wireless link by said wireless transmitter. The first substrate is fixed to or within said second substrate. Additionally or alternatively, the device comprises a first substrate defining one or more microfluidic structures for receiving a fluid to be sensed and a second substrate comprising or having attached thereto a multiplicity of fluid sensors, the number of sensors being greater than the number of microfluidic structures.
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: May 14, 2019
    Assignee: DNAE Group Holdings Limited
    Inventors: Sam Reed, Pantelakis Georgiou, Timothy G. Constandinou