Abstract: Embodiments herein relate to systems and methods for rapidly calibrating optical medical sensors. In an embodiment, a method can include placing a reflective optical medical sensor device on or in a patient. The reflective optical medical sensor device can include one or more optical emitters; one or more optical detectors; and a measurement circuit having one or more transimpedance amplifiers (TIA). The method can include setting the TIA to a fixed gain value and then turning on the optical emitter associated with each spatially unique measurement vector and receiving reflected light with the associated optical detector for each spatially unique measurement vector at the same fixed gain value. The method can include assessing the signal-to-noise (SNR) for each spatially unique measurement vector and selecting the spatially unique measurement vector having the highest SNR. Other embodiments are also included herein.

Abstract: A measuring arrangement for in-vivo determination of the lactate concentration in blood by means of electrochemical impedance spectroscopy, comprising a substantially flat shaped probe having a longitudinal extension, a transverse extension and a thickness, wherein the longitudinal extension and the transverse extension of the probe are each a multiple of the thickness of the probe, an analyzer circuitry connected to the probe, and communication means connected to the analyzer circuitry for transferring data via a WPAN, wherein the substantially flat shaped probe is arranged at an edge of the measuring arrangement, so that the probe, during operation of the measuring arrangement, faces the animal or human body to be examined, in such a manner that the probe is arranged with its longitudinal and transverse extensions approximately parallel to the surface of the body to be examined, a wristband therefor, and a method for the operation thereof.

Abstract: A regional oximetry system comprises a pod having a pod housing defining a sensor end and an opposite monitor end. A dual sensor connector is in electrical communication with the sensor end of the pod housing. A monitor connector is in electrical communication with the monitor end of the pod housing. An analog board is disposed within the pod housing and is in electrical communications with the dual sensor connector. The analog board receives and digitizes sensor signals from at least one optical sensor plugged into the dual sensor connector. A digital board is disposed within the pod housing and in electrical communications with the analog board and the monitor connector.

Abstract: A multipart, non-uniform patient contact interface and method of use are disclosed.

Abstract: An attraction system includes at least one detector, the attraction apparatus, and a controller. The at least one detector detects blood flow information of a user, the attraction apparatus provides at least one stimulus to the user, and the controller is connected to the at least one detector and the attraction apparatus to control the attraction apparatus based on the blood flow information. A control method for the attraction apparatus is executed by the controller and includes: obtaining, from the at least one detector, an amount of change in the blood information before and after the at least one stimulus is provided to the user; and controlling an operation of the attraction apparatus, based on a result of comparison of the amount of change with a threshold.

Abstract: A sensor device which is adapted for detecting target molecules in-vitro and in-vivo, comprises a MIR source for exciting the target species and a probe beam with split frequency to measure the effect of excitation. The latter uses a heterodyne interferometer operating at a beat frequency ˜ KHz. to MHz. The photo-thermal excitation of target species leads to refractive index change. The RI change produces probe beam displacement and is measured using a 1) grating heterodyne interferometer, 2) grating deflection amplifier and 3) evanescent field heterodyne interferometer. The measured RI change can be related to specie concentration change in target volume. Furthermore, a sensing method for detecting HbA1c concentration and its change with thermal excitation is described in terms of phase shift of the OCT spectrum obtained with spectral domain optical coherence tomography (SD-OCT).

Abstract: The present invention provides a device for measuring biological information including a sensor array, wherein the sensor array includes a plurality of sensors that are either sensors for amplifying photoreactivity or sensors forming an island network connected by a plurality of multi-channels and, in the device, the average value of biological information about the skin tissues is measured based on values output from the sensor array, and a method of measuring biological information using the device.

Abstract: System and method for non-invasive monitoring of physiological measurements of a subject, including at least one monitoring device, to detect changes in measured physiological signals, the monitoring device including at least one measuring unit, wherein each measuring unit includes: at least two light emitting sources, and at least one sensor, to detect light beams emitted from the at least two light emitting source, and a computerized device, in communication with the at least one monitoring device, the computerized device to receive data from monitoring device, wherein the monitoring device is configured to be removably attachable to the subject's body.

Abstract: A transceiver for interfacing with an analyte sensor. The transceiver may include an interface device and a notification device. The interface device may be configured to convey a power signal to the analyte sensor and to receive data signals from the analyte sensor. The notification device may be configured to generate one or more of a vibrational, aural, and visual signal based on one or more data signals received from the analyte sensor. The interface device of the transceiver may receive analyte data from the analyte sensor, and the transceiver may comprise a processor configured to calculate an analyte concentration value based on the received analyte data. The notification device may be configured to generate one or more of aural, visual, or vibrational alarm when the calculated analyte concentration value exceeds or falls below a threshold value.

Abstract: An improved analyte monitoring system having a sensor and a transceiver with improved communication and/or user interface capabilities. The transceiver may communicate with and power the sensor. The transceiver may receive one or more analyte measurements from the sensor and may calculate one or more analyte concentrations based on the received analyte measurements. The transceiver may generate analyte concentration trends, alerts, and/or alarms based on the calculated analyte concentrations. The system may also include a display device, which may be, for example, a smartphone and may be used to display analyte measurements received from the transceiver. The display device may execute a mobile medical application. The system may include a data management system, which may be web-based.

Abstract: A transceiver for interfacing with an analyte sensor. The transceiver may include an interface device and a notification device. The interface device may be configured to convey a power signal to the analyte sensor and to receive data signals from the analyte sensor. The notification device may be configured to generate one or more of a vibrational, aural, and visual signal based on one or more data signals received from the analyte sensor. The interface device of the transceiver may receive analyte data from the analyte sensor, and the transceiver may comprise a processor configured to calculate an analyte concentration value based on the received analyte data. The notification device may be configured to generate one or more of aural, visual, or vibrational alarm when the calculated analyte concentration value exceeds or falls below a threshold value.

Abstract: A diagnosis assistance device assists a diagnosis, by using a plurality of sets of biological information that are measured from a subject, and that are stored in a storage medium. The diagnosis assistance device includes an achievement status determining section and a notification processing section. The achievement status determining section determines an achievement status of a predetermined condition related to biological information that is measured from the subject, based on the plurality of sets of biological information stored in the storage medium. The notification processing section performs a process of notifying of the achievement status. The condition is that the pattern of a change of biological information which is stored in the storage medium contains, threshold or more times, a specific pattern. The specific pattern is extreme-dipper, non-dipper, or riser.

Abstract: Various embodiments of the invention provide systems and methods for low-cost, low-power Array Waveguide Grating (AWG)-based miniaturized Raman spectroscopy for use in non-invasive glucose monitoring systems, such as in wearable devices that require no replenishment of chemicals or enzymes. The AWG may be manufactured using VLSI processing technology, which significantly reduces manufacturing cost and replaces holographic grating as the dispersive component of light. In embodiments, the AWG is integrated with a number of PIN photodiode detectors on a substrate to further reduce cost and signal loss. In embodiments, a prism-coupling method eliminates alignment problems associated with traditional approaches that utilize fiber-coupling methods.

Abstract: A transceiver for interfacing with an analyte sensor. The transceiver may include an interface device and a notification device. The interface device may be configured to convey a power signal to the analyte sensor and to receive data signals from the analyte sensor. The notification device may be configured to generate one or more of a vibrational, aural, and visual signal based on one or more data signals received from the analyte sensor. The interface device of the transceiver may receive analyte data from the analyte sensor, and the transceiver may comprise a processor configured to calculate an analyte concentration value based on the received analyte data. The notification device may be configured to generate one or more of aural, visual, or vibrational alarm when the calculated analyte concentration value exceeds or falls below a threshold value.

Abstract: Methods and systems for sensor calibration and sensor glucose (SG) fusion are used advantageously to improve the accuracy and reliability of orthogonally redundant glucose sensor devices, which may include optical and electrochemical glucose sensors. Calibration for both sensors may be achieved via fixed-offset and/or dynamic regression methodologies, depending, e.g., on sensor stability and Isig-Ratio pair correlation. For SG fusion, respective integrity checks may be performed for SG values from the optical and electrochemical sensors, and the SG values calibrated if the integrity checks are passed. Integrity checks may include checking for sensitivity loss, noise, and drift. If the integrity checks are failed, in-line sensor mapping between the electrochemical and optical sensors may be performed prior to calibration.

Abstract: Presented are systems and methods that perform noninvasive glucose monitoring using mid-infrared self-emission of the human body that acts as a background radiation emitter. Various embodiments accomplish this by taking advantage of the guided-mode resonance (GMR) effect in a number of bandpass filters that are constructed as an array of coplanar filters. The filter array acts as a spectral separator that uses a grating layer and a thin film waveguide to form reflection and transmission filters for particular wavelengths. Unlike, common multi-layer optical filter designs that utilize numerous individual optical filters, a novel GMR filter design comprises an array of filters that may be fabricated from CMOS-compatible materials using only a few thin film and grating layers to filter light. Advantageously, this reduces manufacturing cost and allows for simultaneous monitoring of a number of wavelengths of the glucose spectrum.

Abstract: A monitoring system includes a surgical implant configured for implantation in vivo and having at least one sensing fiber configured to measure a preselected physiological parameter, and a receiving unit in wireless communication with the at least one sensing fiber and configured to receive measurements of the preselected physiological parameter. A surgical system includes an end effector having a plurality of fasteners, and a surgical implant securable to tissue via the plurality of fasteners. The surgical implant includes at least one sensing fiber configured to measure a preselected physiological parameter.

Abstract: Hydration measurement capabilities can be provided by a wearable electronic device, such as a watch, to allow a user to easily track hydration. A watch can be positioned to receive and measure one or more electrical properties of perspiration produced by the user wearing the watch. The watch provides electrodes for measuring the electrical properties of the perspiration. The electrical properties, such as electrical conductance, can represent a concentration of electrolytes in the perspiration, which in turn represents a hydration level of the user. The hydration tracking can be performed non-invasively, repeatedly, accurately, automatically, and with minimal user intervention. The measurements can be used to provide useful feedback and health tracking information to a user, thereby allowing the user to better manage hydration and overall health.

Abstract: A gait analyzing device includes: a data acquisition unit acquiring first image data of a walking user and second image data of the walking user from a different direction, using a depth sensor; a skeletal information creation unit creating skeletal information identifying a position of a joint using depth information; a measurement information creation unit creating measurement information identifying a total number of steps and a ground contact history of left and right feet; a common part extraction unit comparing both instances of measurement information and extracts a part from the skeletal information in the first and second image data where the ground contact history is common; a correction processing unit correcting the skeletal information in the image data having the higher number of frames with the skeletal information in the image data having the lower number of frames; and an analysis processing unit analyzing the user's gait.

Abstract: A biopsy device has a flexible sheath having a terminus with a distal chamber. The distal chamber is configured with a forward facing cutting edge. The forwarding facing cutting edge has multiple movable blades, in which the movable blades are two counter rotating blades configured perpendicular or angular to a long axis of the distal chamber. Each counter rotating blade is configured to pivot from a separate axis. The biopsy has a manipulation end controllable by the user to plunge the forward facing cutting edge at a set depth or a depth selected by the user, and to engage a cutting action by the multiple movable blades at the set depth or the selected depth. The movement of the forwarding facing cutting edge enables the biopsy device to acquire a plurality of specimens for storage in the distal chamber.