Patents Examined by Mary Lee
  • Patent number: 4138408
    Abstract: Compounds of the formula ##STR1## in which R.sup.4 represents an alkyl radical having from 1 to 4 carbon atoms,R.sup.5 represents a linear or branched alkylene radical having from 1 to 10 carbon atoms in the chain which may be substituted by groups which are not reactive under the applied conditions, and R.sup.6 represents hydrogen or a branched alkyl radical having from 3 to 10 carbon atoms with a secondary or tertiary N-.alpha.-C atom, are prepared by anodic alkoxylation of lactams of the formula ##STR2## with an alcohol of the formula R.sup.4 OH, in which formulae R.sup.4, R.sup.5 and R.sup.6 have the aforesaid meaning, in the presence of at least one alkali metal or tetraalkylammonium tetrafluoroborate, hexafluoroborate or nitrate as conducting salt, at a temperature of up to about 100.degree. C. in an electrolytic cell with stationary or flowing electrolyte. Some of the products are novel.
    Type: Grant
    Filed: August 17, 1977
    Date of Patent: February 6, 1979
    Assignee: Hoechst Aktiengesellschaft
    Inventor: Michael Mitzlaff
  • Patent number: 4138565
    Abstract: Solutions of certain hydrogenated ergopeptide alkaloids in mixtures of pharmacologically acceptable alcohols and water have improved stability. Preferred solvents are mixtures of ethanol, propylene glycol and glycerol containing from 15-40% wt. of water and having dielectric constants between 34 and 46. With these solutions it is not essential to carry out the filing operation under an inert atmosphere.
    Type: Grant
    Filed: September 15, 1977
    Date of Patent: February 6, 1979
    Assignee: Sandoz Ltd.
    Inventors: Lothar Ehrhardt, Ludwig Patt, Volker Hartmann
  • Patent number: 4136097
    Abstract: A process for the preparation of loweralkyl 2-(N-R'-pyrryl)-.alpha.- loweralkanoic acid esters in increased yield and/or isomeric purity, and copper (II) 1,3-diketonate, copper (II) salicylaldehyde, copper (II) monoamino-1,3-diketonate, and copper (II) salicylaldimine complexes useful as promoting agents for said process.
    Type: Grant
    Filed: April 6, 1977
    Date of Patent: January 23, 1979
    Assignee: McNeil Laboratories, Inc.
    Inventor: Bruce E. Maryanoff
  • Patent number: 4134894
    Abstract: Pyrrolo[1,2-a]indole compounds having in free base form the formulas ##STR1## where R.sub.1, R.sub.2 and R.sub.3 are lower alkyl; R.sub.4 is lower alkyl, phenyl, lower alkoxy or ##STR2## in which R.sub.8 and R.sub.9 are hydrogen, lower alkyl, phenyl or benzyl; R.sub.5 is hydrogen or lower alkyl; A is O or NH; and R.sub.6 and R.sub.7 are lower alkyl, phenyl, or carbo(lower)alkoxy.
    Type: Grant
    Filed: May 4, 1978
    Date of Patent: January 16, 1979
    Assignee: Warner-Lambert Company
    Inventors: Harold Zinnes, Martin L. Schwartz