Abstract: The present invention relates to a device and a method for qualitative and quantitative analysis of heavy metals and more particularly provides a device and a method for qualitative and quantitative analysis of heavy metals utilizing a rotary disc system.

Abstract: A fluid dispenser having a reservoir (R) containing fluid (P) and air (A), the reservoir (R) forming an assembly opening (11); a fluid dispenser cannula (12) in communication with the reservoir (R); and an actuator member (2) engaged in the assembly opening (11), for supplying the dispenser cannula (13) with fluid (P). The actuator member (2) has a deformable membrane (23) that defines an outside face (231) forming a pusher (24), and an inside face (232) that is in contact with the air (A) of the reservoir (R), when the dispenser cannula (12) is in contact with the fluid (P) of the reservoir (R).

Abstract: The present disclosure related to an apparatus that may be used for taking blood glucose measurements and providing individualized insulin dose recommendations wherein the apparatus is easy to use and facilitates improved diabetes control in patients. Also disclosed are related methods.

Abstract: The present invention relates to a device and a method for qualitative and quantitative analysis of heavy metals and more particularly provides a device and a method for qualitative and quantitative analysis of heavy metals utilizing a rotary disc system.

Abstract: Described herein are systems and methods of providing a nanosensor chip for detecting and/or quantifying target molecules in a solution. Said nanosensor chip comprises a pore comprising a plurality of nanopores. Said plurality of nanopores is functionalized with immobilized probe molecules for detecting the target molecules. The solution is directed to the nanochip to permit binding of said target molecules. Changes an aggregate current in response to target molecules in the liquid sample binding to the probe molecules are measured to detect and/or quantify said target molecules in said solution.

Abstract: The invention relates to an apparatus for receiving a body fluid, wherein the apparatus comprises a first chamber with a displaceable wall and a second chamber of a constant effective size, said second chamber being movable with respect to the displaceable wall, wherein the apparatus is designed to connect the first chamber and the second chamber during a longitudinally axial movement of the second chamber with respect to the displaceable wall and to transfer body fluid from the first chamber to the second chamber during a movement of the second chamber together with the displaceable wall.

Abstract: A method of acquiring a sample for evaluation of a SiC single crystal, comprising: a step of cutting a SiC ingot in a radial direction at a thickness position, which is located in a range from a curved surface which forms a distal end surface in a crystal growth direction to a seed crystal, to obtain a head member which includes the curved surface, wherein the SiC ingot used in the step is a SiC ingot in which SiC thereof is crystal-grown from a seed crystal along a c axis direction; and a step of polishing a silicon surface of the head member to obtain a sample for evaluation.

Abstract: The invention relates to a method for preparing a substrate (105a) comprising a sample reception area (110) and a sensing area (111). The method comprises the steps of: 1) applying a sample on the sample reception area; 2) rotating the substrate around a predetermined axis; 3) during rotation, at least part of the liquid travels from the sample reception area to the sensing area due to capillary forces acting between the liquid and the substrate; and 4) removing the wave of particles and liquid formed at one end of the substrate. The sensing area is closer to the predetermined axis than the sample reception area. The sample comprises a liquid part and particles suspended therein.

Abstract: Sensor clip assemblies, sensor clips, analyte testing systems, and methods for making and using the same are disclosed. A sensor clip assembly is disclosed for storing and dispensing analyte testing sensors. The sensor clip assembly includes numerous test sensors arranged in a stack. Each test sensor is configured to assist in testing an analyte in a fluid sample. The sensor clip assembly also includes a skeletal frame with a top, a bottom, and numerous sides. The top, bottom and sides are interconnected to define an internal chamber within which is stored the stack of test sensors. At least one of the sides includes one or more elongated rails with structural gaps on opposing sides thereof. For some configurations, multiple sides of the skeletal frame comprise at least one or multiple elongated rails, each of which has structural gaps on opposing sides thereof and may be columnar in nature.

Abstract: One aspect of the present invention is to provide the device and methods for performing an assay that uses the multiplexing of sample thicknesses on the same plate. The sample thickness multiplexing can offer many information that are unavailable in using a single sample thickness.

Abstract: A system for detecting COVID-19 infection, including a colorimetric sensor, an image-capturing device, and a processing unit connected to the image-capturing device. The colorimetric sensor includes an injection zone and a detection zone patterned on a paper, where the injection zone covers the detection zone by folding the paper. The injection zone is configured to inject a saliva sample acquired from a person thereon. The detection zone includes an array of chemical receptors configured to interact with the injected saliva penetrating into the detection zone. The processing unit is configured to perform a method of capturing a first image from the detection zone before injection of the saliva sample, capturing a second image from the detection zone after injection of the saliva sample, and detecting COVID-19 infection status of the person by analyzing color changes of the array of chemical receptors in the second image respective to the first image.

Abstract: A specimen collection, storage, transport, and testing device (1) can include an outer vessel (2) containing an internal cup (5) having an openable drain (23) having a brim (22) raised above the bottom floor (27) of the cup. Once opened the drain allows a portion of liquid specimen to flow from the cup into a lower chamber (55) of the vessel and onto a cartridge (3) containing a number of chromatographic assay strips. A lid (4) sealing the vessel can include a downwardly projecting guide tube (35) having first barrier (39) sealing a bottom aperture (38). An oblong initiator (6) can axially engage the guide tube, break the first barrier and open the drain to initiate the test while retaining a pool of liquid specimen in the cup for subsequent confirmatory testing.

Abstract: In one aspect of the present disclosure is a method of contactlessly urging, directly, or moving a substance on the surface of a substrate, the method employing a gas knife (300) configured to produce a gas curtain having parallelogram flow.

Abstract: Devices and methods are provided for electrically lysing cells and releasing macromolecules from the cells. A microfluidic device is provided that includes a planar channel having a thickness on a submillimeter scale, and including electrodes on its upper and lower inner surfaces. After filling the channel with a liquid, such that the channel contains cells within the liquid, a series of voltage pulses of alternating polarity are applied between the channel electrodes, where the amplitude of the voltage pulses and a pulse width of the voltage pulses are effective for causing irreversible electroporation of the cells. The channel is configured to possess thermal properties such that the application of the voltage produces a rapid temperature rise as a result of Joule heating for releasing the macromolecules from the electroplated cells. The channel may also include an internal filter for capturing and concentrating the cells prior to electrical processing.

Abstract: An apparatus for performing nucleic acid amplification reactions includes a thermally-conductive receptacle holder with front and back surfaces. The front surface includes a row of receptacle wells, and an outer surface of each well has a frustoconical shape, an inner surface of each well receives a receptacle, and each well has a through-hole extending between the inner and outer surfaces thereof. One or more thermal elements in contact with the back surface of the holder alter a temperature(s) of the holder. The apparatus includes multiple optical fibers, and each optical fiber provides optical communication between one of the wells and an excitation signal source and/or an emission signal detector. A first end of each optical fiber is disposed outside, within, or extends through the through-hole of a corresponding well, and a second end of each optical fiber is in optical communication with the excitation signal source and/or the emission signal detector.

Abstract: Embodiments of the invention include instruments and methods useful in preparing and delivering graft material to a surgical site. Some embodiments may particularly be directed to forming a graft from a blood clot and accurately and effectively handling and delivering the graft to a surgical site. Graft material may include blood components such as clotted fibrin derived from a patient's or a donor's blood.

Abstract: The invention relates to kits and components thereof used in the conduct of solid-phase binding assays.

Abstract: Embodiments are described for treating a fluid, e.g., a biological fluid. The embodiments may include systems, apparatuses, and methods. Embodiments may provide for a flow cell, with a plurality of manipulation elements, through which a fluid is flowed. The fluid may be treated (e.g., exposed to energy) as it moves through the flow cell. In embodiments, the flow cell may be used to inactivate pathogens in the fluid.

Abstract: A mobile device reads a test strip to determine a chemical condition of a liquid or a user inputs a treatment plan into the mobile device. The mobile device transmits the determined chemical condition or the input treatment plan to a liquid treatment system which treats the fluid in response to the determined chemical condition or the input treatment plan.

Abstract: An apparatus for manipulating magnetic particles includes a latch mechanism. The latch mechanism has a pivoting part provided on a door and an engaging part provided on a main body. In the apparatus for manipulating magnetic particles, a first contact portion of a latch engages with the engaging part at a contact point in a state that the door is closed. The contact point is located more outside of the main body than the pivot axis. Accordingly, in a case where an external force is applied to the door in a direction to open the door in a state that the door is closed, a force is applied from the engaging part to the first contact portion, thereby generating a rotational force in a C direction to the pivoting part. As a result, in the state that the door is closed, it is possible to suppress the door from being opened without a manipulation by the user.