Patents Examined by Matthew D Krcha
  • Patent number: 11759786
    Abstract: According to an example aspect of the present invention, there is provided an apparatus for mounting a device on a manipulator, wherein a second unit is adjustably attached to a first unit so that it is movable in at least one direction with respect to the base plate and wherein the first unit has at least a locked position and an open position, the mounting rail being movable with respect to the first unit when the first unit is in the open position and wherein the mounting rail is fixed with respect to the first unit when the first unit is in the closed position.
    Type: Grant
    Filed: January 29, 2021
    Date of Patent: September 19, 2023
    Assignee: Sartorius Biohit Liquid Handling Oy
    Inventor: Anssi Häärä
  • Patent number: 11759783
    Abstract: The present invention relates to an assay device for determining the presence and/or amount of an analyte of interest in a sample, the assay device comprising: a) a housing that includes a liquid receiving unit that is adapted to accommodate one or more types of liquid; b) a mixing chamber adapted for containing a solution that is a product of one more types of liquid, and for receiving a sample to interact with said solution; c) an actuating lid which is capable of being actuated to enable the transfer of the liquid into the mixing chamber; and d) an assay means that is in fluid communication with said mixing chamber for determining the presence and/or amount of an analyte of interest in the sample after the interaction of said sample with said solution in the mixing chamber.
    Type: Grant
    Filed: November 24, 2016
    Date of Patent: September 19, 2023
    Assignee: Novamed Ltd.
    Inventors: Emil Katz, Gadi Porath, Ural Rashitov
  • Patent number: 11754555
    Abstract: According to a pad which is used for an immunochromatographic device for extracting a substance to be detected contained in a detection target in an analyte with nitrous acid and which contains an acid anhydride having vapor pressure at 25° C. of 5×10?2 Pa or less and solubility in water at 25° C. of 0.1 mg/L or more, the storage stability is improved; a substance to be detected contained in an analyte is detected with high sensitivity; and the complexity of production is reduced.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: September 12, 2023
    Assignee: TANAKA KIKINZOKU KOGYO K.K.
    Inventor: Hiroshi Kishi
  • Patent number: 11752502
    Abstract: A reagent pack includes a first reservoir having a continuous rigid wall defining a constant inner space that opens to the ambient environment. An air-tight second reservoir has a flexible wall that defines a variable inner space with one or more second openings. The second reservoir is arranged within the first reservoir and stores fluid reagent. A closure element completely fills the first opening of the first reservoir and includes a first fluid passage fluidly connecting the inner space of the first reservoir, as the waste reservoir, to receive waste liquid. Second fluid passages fluidly connect the second openings of said second reservoirs with respective reagent inlets to supply fluid reagent to the sample analyzer. The inner space of the first reservoir further includes an air passage to allow gaseous communication with the ambient environment to maintain a controlled pressure within said inner space while receiving waste liquid.
    Type: Grant
    Filed: June 14, 2017
    Date of Patent: September 12, 2023
    Assignee: DIATRON MI ZRT.
    Inventors: Dániel Gergely Isztli, Barna Reskó, Bence Salló
  • Patent number: 11747266
    Abstract: A system for irradiating a microplate may include a modular light engine with one or more light emitting devices. The light emitting devices are configured to emit germicidal radiation to irradiate the microplate, which is configured to be positioned below the modular light engine inside a chamber of the microplate irradiation system. In this way, a uniform intensity of germicidal radiation may be output by light emitting devices, resulting in disruption of contaminating nucleic acids present in the microplate.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: September 5, 2023
    Assignee: Phoseon Technology, Inc.
    Inventors: John Christopher Freitag, Theresa Thompson, Garth Eliason, Jay Pasquantonio
  • Patent number: 11747329
    Abstract: Disclosed herein are devices for molecule detection and methods for using detection devices for molecule detection, such as nucleic acid sequencing. In some embodiments, a detection device comprises one or more pole pieces, one or more sensors, each of the one or more sensors coupled to at least one of the one or more pole pieces, and detection circuitry coupled to the one or more sensors. The detection circuitry is configured to detect a characteristic of each of the one or more sensors, the characteristic indicating presence or absence of one or more magnetic nanoparticles (MNPs) coupled to at least one of a plurality of molecules to be detected, and at least one of the one or more pole pieces is operable to draw the one or more MNPs toward at least one of the one or more sensors.
    Type: Grant
    Filed: March 19, 2020
    Date of Patent: September 5, 2023
    Assignee: Western Digital Technologies, Inc.
    Inventor: Daniel Bedau
  • Patent number: 11745177
    Abstract: A system and method for lysing of whole blood for CO-Ox measurement uses a lysing chamber for acoustic lysing of whole blood in a module in which the lysing chamber is separate from a CO-Ox measurement chamber. The disclosed acoustic lysing system and method avoids the expense and complexity of chemical lysing methods and allows the whole blood sample to be lysed while under continuous flow through the lysing chamber. The acoustic lysing chamber is provided upstream from a CO-Ox measurement chamber. The separation of the lysing chamber from the Co-Ox measurement chamber provides freedom to arrange and orient various optical components and/or other CO-Ox measuring components around the CO-Ox measurement chamber. The decoupling of the lysing chamber from the CO-Ox measurement chamber allows for more efficient design of the ultrasonic lysing transducer and CO-Ox measurement optics.
    Type: Grant
    Filed: January 9, 2020
    Date of Patent: September 5, 2023
    Assignee: INSTRUMENTATION LABORATORY COMPANY
    Inventors: Brian Joseph Bosy, Josef Kerimo
  • Patent number: 11740256
    Abstract: Systems for processing a fluid sample to facilitate analysis with a semiconductor detection chip are provided herein. Such systems can include a sample processing cartridge coupleable with a chip carrier device configured for transport of the processed fluid sample from the sample cartridge. The chip carrier device can include one or more fluid channels extending between fluid-tight couplings attachable to transfer ports of the sample processing cartridge. The chip carrier device can include multiple portions or adapters, including a fluid sample portion, a flowcell portion and a chip carrier. Also provided are methods of preparing and transporting a fluid sample from a sample cartridge into a chip carrier device for analysis with a semiconductor detection chip carried within the chip carrier device.
    Type: Grant
    Filed: September 20, 2019
    Date of Patent: August 29, 2023
    Assignee: Cepheid
    Inventors: Douglas B Dority, Jonathan Siegrist, Ronald Chang
  • Patent number: 11740198
    Abstract: [Object] To provide a formaldehyde detecting sensor capable of constantly monitoring formaldehyde selectively and with high accuracy. [Solving Means] A formaldehyde detecting sensor according to the present invention includes: a reaction portion that contains at least a hydroxylamine salt and reacts with formaldehyde to generate an acid; and a response unit that includes an electrode carrying a carbon material, an electrical resistance value of the carbon material varying depending on the acid generated in the reaction portion, in which the hydroxylamine salt and the carbon material are separated from each other.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: August 29, 2023
    Assignee: NATIONAL INSTITUTE FOR MATERIALS SCIENCE
    Inventors: Shinsuke Ishihara, Jan Labuta, Takashi Nakanishi
  • Patent number: 11739883
    Abstract: Embodiments of disclosure generally relate to corrosion sensors for storage tank applications, using corrosion responsive members and sensors to monitor corrosion in storage tanks, and methods for monitoring corrosion in a storage tank using the corrosion sensors. In one embodiment, a corrosion sensor for a storage tank comprises one or more sensors located on a non-process side of the storage tank and one or more corrosion responsive members located internal to the one or more sensors. The one or more sensors are configured to monitor a change in one or more physical properties of the one or more corrosion responsive members. Data from the corrosion sensor may be monitored locally or transmitted over a network and monitored remotely.
    Type: Grant
    Filed: September 16, 2020
    Date of Patent: August 29, 2023
    Inventor: Paul A. Cohen
  • Patent number: 11730458
    Abstract: A fluid sample testing apparatus has a fluid collector tube and a fluid collector in fluid communication with a sample holding container. The fluid collector is inserted into and penetrates the fluid collector tube and pressure is generated to release fluid from the fluid collector into the sample holding container, and air passes outside of the apparatus from the fluid collector tube via a vent path. The vent path is sealed with the fluid collector is fully inserted into the fluid collector tube. Indicator or test strips are optionally included in a stem of the fluid collector.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: August 22, 2023
    Assignee: MARSHALL VENTURE PARTNERS LLC
    Inventors: Alan R Loudermilk, Herbert Hunt Allred, Kevin Fuller, Wayde J Altendorf
  • Patent number: 11731134
    Abstract: Example apparatus including septums and related methods are disclosed. An example apparatus includes a septum that includes a first surface and a membrane coupled to at least a portion of the first surface. In addition, the example septum includes a second surface and ribs extending between the membrane and the second surface.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: August 22, 2023
    Assignee: ABBOTT LABORATORIES
    Inventor: Robert P. Luoma, II
  • Patent number: 11724255
    Abstract: A fluid sample testing apparatus has a housing with a test chamber and first and second fluid collector tubes and first and second fluid collectors in fluid communication with the test chamber. A sample holding container is in fluid communication with the second fluid collector tube. The first fluid collector is inserted into the first fluid collector tube and pressure is generated to release fluid from the first fluid collector into the test chamber, and air passes outside of the apparatus from the test chamber via an opening from the test chamber into the first fluid collector tube. The second fluid collector is inserted into the second fluid collector tube concurrently and pressure is generated to release fluid from the second fluid collector into the sample holding container, and air passes outside of the apparatus from the second fluid collector tube.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: August 15, 2023
    Assignee: MARSHALL VENTURE PARTNERS LLC
    Inventors: Alan R Loudermilk, Herbert Hunt Allred, Kevin Fuller, Wayde J Altendorf
  • Patent number: 11724258
    Abstract: A method includes engaging a well of a cartridge with a flow sensor of an instrument. The cartridge includes: a rotary valve including a rotatable port and a center port; the well in fluid communication with a channel, the channel including a channel port that the rotatable port is to align to in order to receive fluid from the well; and a flowcell including an inlet gasket in fluid communication with the center port. A source of pressurized air is connected to the flow sensor in order to establish a mass flow of air through a flow path. The flow path extends through one of the flow sensor, the channel, the rotary valve, and the flowcell. The mass flow of air through the flow path is measured with the flow sensor. It is determined if there is one of an air leak and an air blockage within the flow path.
    Type: Grant
    Filed: May 23, 2022
    Date of Patent: August 15, 2023
    Assignee: ILLUMINA, INC.
    Inventors: Sz-Chin Steven Lin, Richard Lemoine, Rajagopal Panchapakesan, Wesley A. Cox-Muranami, Darren Segale
  • Patent number: 11724254
    Abstract: Aspects of the invention relate to liquid transfer systems including a pipette tip having a body defining an inner volume and having first and second ends, the first end arranged to transfer a volume of liquid into and out of the pipette tip and the second end arranged for attachment to a pipette, and a bladder sealingly attached to the body. In some embodiments, the bladder is disposable in the inner volume. The bladder may be defined by a membranous sac and/or a planar membrane. The bladder may be moveable in response to an applied pressure to transfer liquid. The bladder also may be stretchable to accommodate a volume of fluid. In some embodiments, the pipette tip is used in a cell culture incubator, with a manipulator including a pipette that is in fluid communication with the pipette tip.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: August 15, 2023
    Assignee: Thrive Bioscience, Inc.
    Inventor: Alan Blanchard
  • Patent number: 11719701
    Abstract: A blood glucose level measuring chip exhibits excellent blood spreading ability and can maintain a reaction rate of blood with a reagent, even where the blood has a high hematocrit value (Ht). The blood glucose level measuring chip includes a blood glucose level measuring reagent including a supply port through which blood is supplied, a flow path having the supply port formed at one end of the flow path, and a blood glucose level measuring reagent containing an aromatic hydrocarbon having at least one sulfonic acid group disposed on an inner wall defining the flow path, wherein a ratio A/B is 3.7 mmol/L or more to 184.8 mmol/L when A (mmol) represents the total molar amount of aromatic hydrocarbons contained in the blood glucose level measuring reagent, and B (L) represents a volume of a region in which the blood glucose level measuring reagent and the blood are dissolved.
    Type: Grant
    Filed: December 17, 2019
    Date of Patent: August 8, 2023
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Fumihiko Chai, Takeyuki Moriuchi
  • Patent number: 11714069
    Abstract: A microfluidic diagnostic device comprises a base and at least one switch coupled to a portion of the base, the switch comprising a flap that is pivotable with respect to the base from a first position spaced away from the base a first distance to a second position where the flap is spaced away from the base a second distance. Both the base and the switch comprise one or more channels that permit passive transportation of an aqueous solution. The switch may be formed by bending or deforming a strip to cause the flap to be in the first position when there is less than a predetermined amount of fluid within the channel of switch. When a predetermined amount of fluid is in the channel of the switch, the flap pivots to the second position, which may be achieved through power from gravity, capillarity, and/or inherent elastic energy.
    Type: Grant
    Filed: May 28, 2019
    Date of Patent: August 1, 2023
    Assignee: NORTHERN ILLINOIS RESEARCH FOUNDATION
    Inventors: Korampally Venumadhav, Kevin Dotseth, Yashodeep Patil
  • Patent number: 11714057
    Abstract: A gas sensor device includes a first electrode, a second electrode, and a polythiophene film which is formed between the first and second electrodes to be electrically coupled to the first and second electrodes, and to which cuprous bromide is adsorbed.
    Type: Grant
    Filed: May 24, 2021
    Date of Patent: August 1, 2023
    Assignee: FUJITSU LIMITED
    Inventors: Satoru Momose, Michio Ushigome, Kazuaki Karasawa, Osamu Tsuboi
  • Patent number: 11713442
    Abstract: Manufacturing system and method for creating multiple tissue constructs from cells. System can include a thaw subsystem (if the cells are provided in a frozen state), an expansion subsystem, a concentration subsystem, and a tissue maturation subsystem. Each of these subsystems is modular and can be reconfigured, and the process can be repeated depending on the specific tissue process being implemented. Multiple tissue types can be combined in multiple bioreactors. The activities of multiple bioreactors can be coordinated and controlled in an automated manner by a supervisor controller. The supervisor controller can receive user input at the start of the process, and can manage the process henceforth, alerting the user if user actions are required.
    Type: Grant
    Filed: June 17, 2020
    Date of Patent: August 1, 2023
    Assignee: DEKA PRODUCTS LIMITED PARTNERSHIP
    Inventors: Richard E. Andrews, Stephanie M. Miskell, Zachary T. Kops, Justin M. Ferrentino, Michael C. Tilley, Andrew K. Capulli, Keira L McGrath, Stuart A. Jacobson
  • Patent number: 11712691
    Abstract: A biological fluid separation device and a separation process that allows for efficient separation of plasma from a blood sample is disclosed. A biological fluid separation device of the present disclosure is adapted to receive a blood sample having a cellular portion or cells and a plasma portion or plasma. A biological fluid separation device of the present disclosure separates plasma from cells using a track-etched membrane and cross-flow filtration.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: August 1, 2023
    Assignee: Becton, Dickinson and Company
    Inventors: Milan Ivosevic, Peng Li, Scott Wentzell