Abstract: Injection device comprising a tubular elongated main body, a needle shield slidably arranged in said main body, a needle shield link slidably connected to said needle shield, a enclosure containing medicament arranged in said main body, a needle connected to said enclosure, a plunger operatively arranged to said enclosure for ejecting said medicament through said needle and arranged on its upper part with a number of outwardly extending stop members, spring means arranged to said plunger for operating said plunger, a dose activating means, a needle shield spring surrounding the needle shield link.

Abstract: Embodiments are directed to portable infusion devices, systems, and methods of using the same for dispensing materials. In some cases, the devices, systems and methods may be used for infusing a material such as medicament, e.g., insulin, into a body in need thereof.

Abstract: A barrier system is provided for use in reducing infections associated with post-operative surgical incision and/or a percutaneous medical device, such as a catheter, that is disposed within the surgical incision. Such a barrier system may include: a barrier device having a skin-contacting surface and a catheter-receiving surface; and an adhesive composition configured for adhering to skin, the barrier device, and/or the catheter so as to form a barrier at or adjacent to an incision in the skin where the catheter is percutaneously inserted through the skin. A tensioning anchor and associated system of two or more tensioning anchors is provided for post-operative wound closure. A method for applying and removing the barrier device and tensioning anchors is also provided.

Abstract: An absorbent pant is provided with a containment system defined by a wearing-facing surface of the absorbent pant. The containment system comprises at least one of the following: a pleated section comprising a plurality of pleats; a channeled section comprising a plurality of alternating ridges and channels; and/or a bubbled section comprising a plurality of hemispherical-shaped bubbles aligned in a plurality of rows.

Abstract: A method and apparatus for inserting a conventional flexible catheter with a pre-attached connector on the proximal end into a vessel, such as a vein or artery in a cardiovascular system, while monitoring blood pressure. The catheter drive assembly has an external drive input for advancement and retraction of the flexible catheter. The catheter drive assembly has cylindrical catheter drives that can be engaged to or disengaged from the flexible catheter without causing damage to the flexible catheter. The flexible catheter distal end provides fluid communication to a disposable blood pressure transducer. The flexible catheter is completely encapsulated within a protective sleeve and within the catheter drive assembly, creating an aseptic insertion environment, eliminating the need for sterile barrier protection. Once the flexible catheter is inserted to the desired position, the protective sleeve and catheter drive assembly are removed from the flexible catheter leaving the flexible catheter.

Abstract: A sheath introducer for a catheter includes a sheath having a lumen, a hub positioned on a proximal end of the sheath, and a housing positioned on the hub. The hub can include a splittable penetration member having a port in fluid communication with the sheath lumen. The housing can include a valve having a closed upper surface and a channel surrounding the splittable penetration member. Movement of the housing with respect to the hub can expose the port of the splittable penetration member for insertion of the catheter.

Abstract: The present invention is an electro-mechanical external skin pulling device for users to pull/stretch and hold in place their skin in an easy, reliable, safe and predictable manner to enable facial, eye, cheek, neck and/or throat appearance modifications, integrated with an optional wireless remote control adjustment/monitoring system using either a mobile communication device running an application for the present invention or a dedicated remote control device to adjust and maintain the desired skin alteration.

Abstract: A device for sustained delivery of a poorly water soluble drug is described. A drug reservoir within the device, when in operation, contains an aqueous suspension of the drug mixed with a suspension of an excipient that, in one embodiment, generates acidic groups for a sustained period of time to maintain a desired pH in the aqueous suspension that in turn provides a constant concentration of a soluble form of the drug.

Abstract: According to aspects of the present disclosure, a system may include a loading device including an exterior surface. The system may also include an expandable member mounted on the exterior surface of the loading device. The expandable member may be configured to selectively transition between a collapsed state and an expanded state. The system may also include a covering mounted on the expandable member. The covering may extend around the expandable member and the loading device. The loading device may be configured to position the expandable member and the covering for mounting on an exterior surface of an elongate introduction sheath.

Abstract: An apparatus for improving the quality of the existing ultrasound diagnostic examination by non-invasively determining a type of tissue matter within a living entity consisting of application of two different ultrasound diagnostic methods simultaneously, in a sequence or alternate through the same transducer is disclosed. The apparatus uses a B-scan tissue image visualization as a guiding image to apply a tissue characterization method to determine an attenuation data for tissue matter and includes the steps of applying arbitrary waveform generator to produce a B-scan image of the tissue matter to be analyzed, selecting a region of interest on said image, detecting reflected signals from said region of interest, analyzing the reflected signals to determine attenuation data for the tissue matter.

Abstract: The invention relates to an insertion device comprising —a penetrating member (50) connected to transformation means (52), —a moving part (38) comprising guiding means (39) which guiding means (39) restrict the movement of the transformation means (52) and guide the penetrating member (50) from a first to a second position in a first direction, i.e. the direction of insertion, towards the injection site, and —a stationary housing (30) comprising guiding means (32) which guiding means (32) restrict the movement of the moving part (38). The guiding means (32) guide the moving part (38) in a second direction which is linear and different from the first direction i.e. the direction of insertion.

Abstract: Embodiments are directed to portable infusion devices, systems, and methods of using the same for dispensing materials. In some cases, the devices, systems and methods may be used for infusing a material such as medicament, e.g., insulin, into a body in need thereof.

Abstract: A portable insulin pump can integrate and display data from a continuous glucose monitor (CGM) to allow a user to more readily determine whether any interaction with the pump is necessary. Data from the CGM can automatically be transmitted to the pump and can be displayed for user analysis or automatically analyzed to present recommendations to the user based on combined data from the CGM and the pump.

Abstract: An apparatus includes a housing, a medicament container and a movable member. The medicament container is configured to move within the housing between a first position and a second position in response to a force produced by an energy storage member. A proximal end portion of the medicament container includes a flange and has a plunger disposed therein. A first shoulder of the movable member is configured to exert the force on the flange to move the medicament container from the first position to the second position. A portion of the first shoulder deforms when the medicament container is in the second position such that at least a portion of the force is exerted upon the plunger. A second shoulder of the movable member is configured to exert a retraction force on the flange to move the medicament container from the second position towards the first position.

Abstract: Described herein are methods and devices for selectively applying fluids (particularly anesthetics) to a target tissue from within a blood vessel while minimizing the amount of fluid applied to non-target tissue. The injection catheters described herein may include an elongate body, a directional injector, and one or more holdfasts for securing the catheter before extending the injector. The methods of selectively applying anesthetic to a target structure generally include the steps of inserting an injection catheter into a body vessel, positioning the injection catheter within the body vessel near the target structure, anchoring the injection catheter before extending a directional injector from the injection catheter, and applying anesthetic from the injection catheter to the target structure.

Abstract: A surgical apparatus for removing deposits from an interior of a vessel including an outer member and a rotatable shaft having a lumen to receive a guidewire. The lumen has a cross-sectional dimension to enable fluid injection between an inner diameter of the shaft and an outer diameter of the guidewire. A tip is mounted to the shaft for rotation about its longitudinal axis and mounted such that the distal opening of the shaft is axially spaced from a distal internal surface of the tip such that fluid injected through the lumen of the shaft contacts the distal internal surface of the tip and is redirected proximally to direct in a proximal direction deposits removed by the rotational movement of the shaft. The tip includes including a guidewire lumen for receiving a guidewire to enable over the wire insertion of the apparatus.

Abstract: Disclosed is a system for interacting with a cell and further communicating over a communication network is provided. The system includes a controller, a frequency generator, a first electrode, and a cell-chip circuitry. The frequency generator provides modulated alternating electric field with variable frequency. The controller releases routing instructions and further communicates through the communication network. The first electrode receives alternating electric field charges from the controller. The cell-chip circuitry is capacitively coupled to the first electrode. The cell-chip circuitry includes a second electrode, a harvester, a processor, a pulser, an analog switch matrix, a bi-directional communication unit, a pit, an inherent artificial intelligence interpreter, a analyzer, a nano needle, a third electrode. The cell-chip circuitry measures the field strength of the received charges from the harvester and generates pulsed intervals depending upon the field strength.

Abstract: An apparatus includes a housing, a medicament container and a movable member. The medicament container is configured to move within the housing between a first position and a second position in response to a force produced by an energy storage member. A proximal end portion of the medicament container includes a flange and has a plunger disposed therein. A first shoulder of the movable member is configured to exert the force on the flange to move the medicament container from the first position to the second position. A portion of the first shoulder deforms when the medicament container is in the second position such that at least a portion of the force is exerted upon the plunger. A second shoulder of the movable member is configured to exert a retraction force on the flange to move the medicament container from the second position towards the first position.

Abstract: The present invention provides for a deformable, insertable device for relieving intraocular pressure comprising a body portion composed of a biocompatible porous material with pores throughout to permit drainage of fluid from the anterior chamber to the scleral tissue without collapse of the anterior chamber. The invention also includes a method for inserting the device into the eye and for using ultrasound intraoperatively to determine the position of surgical tools and devices within the sclera. The invention also includes a device excising sclera in an eye to create a chamber for insertion of the insertable device into the eye.

Abstract: A medical device for delivery of a fluid to a patient from a line terminating in a tubing needle. The medical device includes a cannula assembly for coupling the fluid into a cannula that is inserted into the patient. The cannula assembly has a first locking element disposed in a fixed position with respect to the cannula. Coupling the line to the cannula assembly is an infusion flap. The infusion flap includes a second locking element for engaging the first locking element of the cannula assembly and a lift tab for disconnecting the infusion flap from the cannula assembly. Coupling of the first and second locking elements requires initial mating of the infusion flap and cannula assembly followed by locking through rotation of the infusion flap with respect to the cannula assembly.