Abstract: Systems and methods are provided for determining the frequency of a cardiovascular pulse based on a first physiological signal that is continuously available and a second physiological signal that is less available and that is more accurate or otherwise improved relative to the first signal with respect to pulse rate estimation. When the second signal is available it controls the determination of the pulse rate. When the second signal is unavailable, the first signal is used to determine the pulse rate. This can include using the first signal to estimate the pulse rate until the second signal is available, at which point the pulse rate is estimated based on the second physiological signal. Alternatively, the first signal could be used to determine a number of candidate pulse rates, and the second signal could be used to select a pulse rate from the set of candidate pulse rates.

Abstract: A yarn has a first conductive yarn having conductivity, a first insulating section covering the first conductive yarn and formed of an insulating material having absorbency, and a second conductive yarn having conductivity and disposed on an outer circumferential side of the first insulating section.

Abstract: A lightweight inflatable vest is provided with embedded listening devices. Once inflated, the vest enables a physician to hear amplified lung sounds and heart beats and rhythms of a patient wearing the vest, via connection to a smart phone application, through a patient portal, or the like. By using the device on a patient, a physician is provided with an accurate way to perform a respiratory and heart health assessment of the patient during a telehealth visit.

Abstract: The present invention relates to a system (1) for estimating cardiovascular fitness of a person, comprising a heart rate monitor (10) for acquiring a heart rate signal including information about the heart rate of the person, an activity monitor (20) for acquiring an activity signal indicative of physical activity of the person, a classifier (30) for classifying the activity of the person based on the acquired activity signal, a selector (40) for selecting one or more heart rate features obtained from the acquired heart rate signal based on the acquired heart rate signal and the classification of the activity for use in an estimation of the cardiovascular fitness of the person, and an estimator (50) for estimating the cardiovascular fitness of the person based on the one or more selected heart rate features.

Abstract: Disclosed are devices and methods for estimating blood pressure, which implement a pulse-transit-time-based blood pressure model that can be calibrated. Some implementations provide reliable and user friendly means for calibrating the blood pressure model using blood pressure perturbation methods and multiple sensors.

Abstract: Method, device and system for providing consistent and reliable glucose response information to physiological changes and/or activities is provided to improve glycemic control and health management.

Abstract: A pressure sensitive device including a body having a proximal portion and a distal portion opposite the proximal portion, the distal portion being made of a shape memory alloy, a flexible diaphragm at least partially surrounding the body and defining a fluid chamber between the flexible diaphragm and the distal portion of the body, and a non-compressible fluid disposed within the flexible diaphragm and exhibiting a hydraulic pressure in communication with the flexible diaphragm.

Abstract: Disclosed herein are systems and methods for producing an illumination pattern in a gas tube of a facially-fitting device, which is used in conjunction with a capnograph. The illumination pattern is determined by at least one illumination parameter, derived at least from measured CO2 data, such that the illumination pattern is indicative of at least one breath-related/physiological parameter and/or one or more of the respiratory/physiological conditions determined/assessed based at least on the CO2 data.

Abstract: Devices, systems, and methods for the localization of body lumen junctions and other intraluminal structure are disclosed. Various embodiments permit clinicians to identify and locate lesions and/or anatomical structures within a lumen and accurately place leads and/or devices within a lumen, through determining the intralumen conductance and/or cross-sectional area at a plurality of locations within the body lumen.

Abstract: A continuous glucose monitoring system may employ complex redundancy to take operational advantage of disparate characteristics of two or more dissimilar, or non-identical, sensors, including, e.g., characteristics relating to hydration, stabilization, and durability of such sensors. Fusion algorithms, Electrochemical Impedance Spectroscopy (EIS), and advanced Application Specific Integrated Circuits (ASICs) may be used to implement use of such redundant glucose sensors, devices, and sensor systems in such a way as to bridge the gaps between fast start-up, sensor longevity, and accuracy of calibration-free algorithms. Systems, devices, and algorithms are described for achieving a long-wear and reliable sensor which also minimizes, or eliminates, the need for BG calibration, thereby providing a calibration-free, or near calibration-free, sensor.

Abstract: A cloud platform comprises a receiving unit and a processing unit. The receiving unit is configured to receive at least one user respiration data set sent by at least one respirator device in at least one uploading cycle. The processing unit is configured to acquire a first user respiration data set sent by a user of one respirator device among at least one respirator device in one uploading cycle, statistically analyze the first user respiration data set on the basis of a stable state value set of the user, and send an alarm signal when the statistical analysis result is determined to be that the first user respiration data set meets a data exception standard. The disclosure provides an on-line user respiration data analysis solution in combination with disease diagnosis of an off-line respiration system, so that the worsening of a patient's conditions can be possibly found in time.

Abstract: Sensor devices including dissolvable tissue-piercing tips are provided. Methods of using and fabricating sensor devices are also provided.

Abstract: An eavesdropping arrangement for acquiring a measured physiological variable of an individual includes a receiver and a communication interface in a housing separate from the receiver. The communication interface is positioned along a communication link between a first sensor, which is configured to measure aortic blood pressure and to provide a signal representing measured aortic blood pressure, and a central monitoring device configured to monitor the measured aortic blood pressure. The communication interface includes a connection to the communication link that permits the communication interface to eavesdrop on the signal representing measured aortic blood pressure such that information representing measured aortic blood pressure is sent to the receiver while allowing the central monitoring device to receive and use the signal representing measured aortic blood pressure.

Abstract: An analyte sensor including an antiglycolytic agent or a precursor thereof and a chelating agent that stabilizes the antiglycolytic agent positioned proximate to the working electrode of the sensor. Also provided are systems and methods of using the electrochemical analyte sensors in analyte monitoring.

Abstract: A method and apparatus for monitoring vital signs, such as cardiopulmonary activity, using a ballistograph are provided. The method and apparatus may be used to monitor an infant sleeping in a crib, a patient in a hospital, a person with a chronic disease at home or in professional care, or a person in an elder-care setting.

Abstract: The invention describes a measuring system for the continuous non-invasive determination of blood pressure at one or more fingers. The fingers chosen for measurement and the adjacent parts of the palm rest on a supporting surface of a housing, which has the shape of a computer mouse. Inside the housing of the “CNAP Mouse”, i.e. underneath the supporting surface for the hand, the pressure generating system is located. The finger sensors are mounted on the supporting surface for the hand. The forearm and the back of the hand are left free and may be used to place intra-venous or intra-arterial access elements. Since the hand will rest on the supporting surface motion artefacts are largely avoided. Tilting or turning of the sensors is hardly possible since the fit of the sensors and thus the coupling of light and pressure are optimized.

Abstract: An adaptive bio-signal feature combining apparatus includes: a feature extractor configured to extract first feature values and second feature values from a bio-signal of an object; a stable interval determiner configured to determine at least one stable interval in the bio-signal; a statistical variable calculator configured to calculate a statistical variable value of a first feature and a statistical variable value of a second feature for each of the at least one stable interval based on the first and second feature values extracted from the at least one stable interval; and a feature combiner configured to calculate an integrated combining coefficient that is used to combine the first feature and the second feature, based on the statistical variable value of the first feature and the statistical variable value of the second feature.

Abstract: A modular electroencephalograph (EEG) system comprises a carrier board comprising one or more electrode connectors, one or more power supplies, and one or more analog-to-digital converter (ADC) modules. Each of the ADC modules comprises multiple input channels, input signal routing, at least one instrumentation power supply, configuration switches for the at least one instrumentation power supply and the input signal routing, an ADC, a programmable gain amplifier, and an ADC communications bus. Each of the one or more ADC modules electrically connects to one of the one or more electrode connectors and one of the one or more power supplies of the carrier board. An embedded computer is configured to run a real time operating system (RTOS), wherein each ADC communications bus of the one or more ADC modules is electrically connected to the embedded computer via a serial interface.

Abstract: A system for monitoring blood pressure includes an implantable medical device (IMD) and an external device (ED). The IMD senses an electrogram (EGM) signal, identifies a feature thereof indicative of a ventricular depolarization, and transmits a conductive communication signal through patient tissue indicating when the ventricular depolarization occurred. The ED is worn against skin and configured to receive the conductive communication signal. The ED is also configured to sense a plethysmography (PG) signal and identify a feature thereof indicative of when a pulse wave responsive to the ventricular depolarization reaches a region of the patient adjacent the ED, and determine a delay time (TD) indicative of how long it takes the pulse wave to travel from the patient's heart to the region of the patient adjacent to the ED. The TD is a surrogate of the patient's blood pressure and useful for monitoring the patient's blood pressure and/or changes therein.

Abstract: A method of measuring vital signals using a millimeter-wave radar sensor system includes performing a first set of radar measurements using a millimeter-wave radar sensor to produce a first set of radar data; determining a first set of range gate measurements from the first set of radar data; determining high response range gates from the first set of range gate measurements; and extracting vital signal information from the high response range gates.