Abstract: The present invention provides a technique for continuous measurement of blood pressure based on pulse transit time and which does not require any external calibration. This technique, referred to herein as the ‘Composite Method’, is carried out with a body-worn monitor that measures blood pressure and other vital signs, and wirelessly transmits them to a remote monitor. A network of body-worn sensors, typically placed on the patient's right arm and chest, connect to the body-worn monitor and measure time-dependent ECG, PPG, accelerometer, and pressure waveforms. The disposable sensors can include a cuff that features an inflatable bladder coupled to a pressure sensor, three or more electrical sensors (e.g. electrodes), three or more accelerometers, a temperature sensor, and an optical sensor (e.g., a light source and photodiode) attached to the patient's thumb.

Abstract: Techniques are described for real-time phase detection. For the phase detection, a signal is correlated with a frequency component of a frequency band whose phase is being detected, and the correlation includes predominantly decreasing weighting of past portions of the signals.

Abstract: A working electrode measuring the presence of an analyte is described as one embodiment. The working electrode includes a working conductor with a reactive surface that is operated at a first potential. The working electrode further includes a first transport material with properties that enable analyte flux to the reactive surface. Additionally, the working electrode has a second transport material with properties that enable reactant flux to the reactive surface, wherein the analyte flux and the reactant flux are in dissimilar directions.

Abstract: According to an aspect, there is provided a method of operating a non-invasive blood pressure, NIBP, monitor to measure the blood pressure of a subject, the NIBP monitor comprising a cuff, a pressure sensor for measuring the pressure in the cuff and for outputting a pressure signal representing the pressure in the cuff and a physiological parameter sensor, the method comprising obtaining a first measurement of a physiological parameter for the subject during inflation of the cuff, the first measurement being obtained from the pressure signal; obtaining a second measurement of the physiological parameter for the subject during inflation of the cuff, the second measurement being obtained from the physiological parameter sensor; comparing the first measurement and the second measurement; and estimating the reliability of a blood pressure measurement obtained by the NIBP monitor during inflation of the cuff based on the result of the step of comparing.

Abstract: A system includes a millimeter-wave radar sensor disposed on a circuit board, a plurality of antennas coupled to the millimeter-wave radar sensor and disposed on the circuit board, and a processing circuit coupled to the millimeter-wave radar sensor and disposed on the circuit board. The processing circuit is configured to determine vital signal information based on output from the millimeter-wave radar sensor.

Abstract: A monitoring and alerting system can be used in any condition with a respiration component. Respiratory symptoms as well as supporting physiological functions are tracked against the user's baseline and alerts the user when there is a worsening trend. The system is self-contained in a wearable that detects and logs the signals, analyzes them and generates alerts. The wearable is untethered during use and may be attached to the body in various manners, such as with adhesives, clothing, clips, belts, chains, necklaces, ear pieces, clothing circuits or the like. Information can further be transmitted both wirelessly and via wire to devices, cloud storage, or the like.

Abstract: An electrode for a user wearable apparatus; the electrode comprising: a conductive part comprising conductive material, wherein the conductive part is configured to provide electrical connection to electronic components of the user wearable device, and an opening configured to provide an optical connection to electronic components of the user wearable apparatus through the electrode.

Abstract: A catheter for measuring a fractional flow reserve includes a proximal shaft, a distal shaft coupled to a distal portion of the proximal shaft, and a pressure sensor coupled to the distal shaft. The distal shaft includes a middle wall portion configured to extend through a stenosis in a vessel. The middle wall portion of the distal shaft includes at least one skive reducing the cross-sectional profile of the middle wall portion. The middle wall portion may further include at least one stiffening wire for increasing columnar stiffness of the middle wall portion.

Abstract: A bio-signal feature scaling apparatus may include: a processor configured to execute instructions to: extract a feature from a bio-signal of an object; estimate a cause of change in a bio-state of the object; calibrate a scale factor based on the estimated cause of change in the bio-state; and scale the extracted feature by applying the calibrated scale factor to the extracted feature.

Abstract: The invention provides a multi-sensor system that uses an algorithm based on adaptive filtering to monitor a patient's respiratory rate. The system features a first sensor which is selected from the group consisting of an impedance pneumography sensor, an ECG sensor, a PPG sensor, and a motion sensor (e.g., an accelerometer) configured to attach to the patient's torso and measure therefrom a motion signal. The system further comprises (iii) a processing system, configured to operably connect to the first and motion sensors, and to determine a respiration rate value by applying filter parameters obtained from the first sensor signals to the motion sensor signals.

Abstract: The present invention provides an apparatus for the measurement and monitoring of the breathing volume of a subject. In certain embodiments, the invention further provides a method of using the apparatus to diagnose a subject as suffering from a respiratory disorder. In other embodiments, the apparatus and method can be used to monitor the breathing volume of a subject, while compensating for random body movement of the subject during the monitoring period.

Abstract: A system for non-invasively determining an indication of an individual's blood pressure is described. In certain embodiments, the system calculates pulse wave transit time using two acoustic sensors. The system can include a first acoustic sensor configured to monitor heart sounds of the patient corresponding to ventricular systole and diastole and a second acoustic sensor configured to monitor arterial pulse sounds at an arterial location remote from the heart. The system can advantageously calculate a arterial pulse wave transit time (PWTT) that does not include the pre-ejection period time delay. In certain embodiments, the system further includes a processor that calculates the arterial PWTT obtained from the acoustic sensors. The system can use this arterial PWTT to determine whether to trigger an occlusive cuff measurement.

Abstract: Infusion devices and related medical devices, patient data management systems, and methods are provided for monitoring a physiological condition of a patient. An exemplary method of monitoring a physiological condition of a patient involves obtaining current measurement data for the physiological condition of the patient provided by a sensing arrangement, obtaining a user input indicative of one or more future events associated with the patient, and in response to the user input, determining a prediction of the physiological condition of the patient in the future based at least in part on the current measurement data and the one or more future events using one or more prediction models associated with the patient, and displaying a graphical representation of the prediction on a display device.

Abstract: A computer-implemented method for quantifying fluid includes estimating a first volume of a first fluid contained in an item based on a difference between a dry weight and a wet weight of the item, and displaying a graphical representation of a container containing a volume of a second fluid and a second volume of the first fluid, wherein the graphical representation includes a first display element for receiving a first user input indicating the volume of the second fluid in the container, and a second display element for receiving a second user input indicating a total fluid volume in the container, estimating the second volume of the first fluid based on at least one of the first and second user inputs, and estimating a quantity of the first fluid based on the first and second volumes of the first fluid.

Abstract: A catheter for measuring a fractional flow reserve includes a proximal shaft, a distal shaft coupled to the proximal shaft, a pressure sensor coupled to the distal shaft, and at least one pressure sensor wire operably connected to the pressure sensor. The proximal shaft includes a radially expanded configuration and a radially collapsed configuration, wherein the proximal shaft has a first outer diameter in the radially expanded configuration and a second outer diameter smaller than the first outer diameter in the radially collapsed configuration. The distal shaft defines a guidewire lumen configured to receive a guidewire therein.

Abstract: An eye-mountable device includes layer(s) of polymer material defining a body. The body includes a first side and a second side extending from a first end to a second end. The first side opposes the second side and curves inwardly toward the second side. The second side curves outwardly away from the first side. The body includes an anterior surface and a posterior surface extending from the first side to the second side and from the first end to the second end. The anterior side opposes the posterior side. The posterior surface has a concave shape. The device includes a substrate in the body including a mounting platform disposed proximally to a middle of the second side. The device includes, on the mounting platform, electronics that interact with a biological environment and monitor health-related information. The body may have a thickness profile that prevents the device from undesired movement.

Abstract: The present disclosure is directed to a method and device to determine the hemoglobin value of a mammal. The device includes a plurality of light emitting diodes, one or more sensors and a processor.

Abstract: A system or method for pressure related skin injury risk assessment and treatment including measuring extrinsic and intrinsic skin pressure of the patient through assigned ratings responsive to the skin pressure measurement, measuring oxygenation of the patient and assigning a rating responsive to the oxygenation measurement, measuring perfusion of the patient and assigning a rating responsive to the perfusion measurement, summing the skin pressure, oxygenation and perfusion ratings to obtain a POP Box score, determining a risk of pressure related skin injury for the patient in response to the POP Box score, and determining or selecting a recommended treatment from among a plurality of recommended treatments for the patient in response to the determined risk of pressure related skin injury.

Abstract: A ventilation monitoring system for assisting in proper placement of an endotracheal tube in a subject includes: a capnography sensor configured to be placed in fluid communication with the endotracheal tube and to provide information representative of the subject's breath; and a processor in communication with the capnography sensor. The processor is configured to provide an indication of proper endotracheal tube placement when (1) a first indication of the subject's breath and a positive result of a first auscultation are identified within a first predetermined time period, and (2) a second indication of the subject's breath and a positive result of a second auscultation are identified within a second predetermined time period. The first auscultation includes auscultation of a subject's left lung, right lung, left axillary region, right axillary region, or abdomen. The second auscultation includes auscultation of another region of the subject different from the first auscultation.

Abstract: A combined exhaled air and environmental gas sensor apparatus for mobile respiratory equipment includes a housing, wherein the housing includes a port aperture, a connector configured to attach the port aperture to a respiratory exhaust port, and at least an ambient aperture connecting to an exterior environment, a sensor positioned within the housing, the sensor configured to detect a carbon dioxide level and generate sensor outputs indicating detected carbon dioxide level, a processor communicatively connected to the sensor, the processor including a memory, a breath analysis mode and an environmental analysis mode, wherein the processor is configured to receive a plurality of sensor outputs from the sensor, match the plurality of sensor outputs to mode parameter profile, and switch between the breath analysis mode and the environmental analysis mode as a function of the mode parameter profile.