Abstract: A non-aromatic tert-amine is oxidized with hydrogen peroxide at about 20.degree.-100.degree. C. by a carbon dioxide-accelerated high solids process in which discoloration of the amine oxide product is minimized by diluting the carbon dioxide before allowing it to contact the reaction mixture so that the entire reaction is conducted in an atmosphere composed of carbon dioxide and an amount of inert gas, such as nitrogen or air, which is at least equal in volume to the amount of carbon dioxide.

Abstract: The present invention provides a process for the preparation of N-cyanoimidocarbonates of the general formula: ##STR1## in which R.sup.1 and R.sup.2 are the same and are alkyl radicals containing up to 4 carbon atoms or R.sup.1 and R.sup.2 are joined together to give an ethylene or propylene chain which is optionally substituted by an alkyl radical containing up to 3 carbon atoms, wherein an imidocarbonate obtained in aqueous alkaline solution from the appropriate alcohol and cyanogen chloride is added with an acid to an aqueous solution of cyanamide in such a manner that the reaction mixture has a pH value of from 3 to 8.

Abstract: A method for stimulating the intracellular synthesis of glutathione comprising the step of administering to a mammal a therapeutically effective amount of an ester of 2-oxothiazolidine-4-carboxylate is provided.

Abstract: Positive photoresists formulations for producing positive photoresist images having improved thermal stability yet which allow a wide variation in resin to photoactive sensitizer compound without significant changes in photospeed, thermal behavior, contrast or resolution and with virtually no less in unexposed areas of the photoresist and without significant outgassing or popping are provided by employing novel 1,2-diazonaphthoquinone-4- or -5- sulfonate esters of 2,3,4,3',4',5'-hexahydroxybenzophenone with a novel isomeric distribution of esters. The novel isomeric distribution of 1,2-diazonaphthoquinone-4- or -5- sulfonate esters of 2,3,4,3',4',5'-hexahydroxybenzophenone is characterized by two major isomers, together comprising at least about 70% by weight of the photoactive compound, and wherein the least polar isomer comprises only about 40%.

Abstract: New .alpha.-trifluoromethyl-substituted, saturated bicyclic amines of the formula ##STR1## in which R.sup.1 represents hydrogen, C.sub.1 - to C.sub.8 -alkyl or C.sub.1 - to C.sub.8 -alkoxy,R.sup.2 represents hydrogen or C.sub.1 - to C.sub.4 -alkyl,n represents zero or 1,A represents ##STR2## B represents NH or ##STR3## and C represents ##STR4## in which A, B and C are either each different from one another or C represents ##STR5## and one of A and B represents NH and the other represents ##STR6## and R.sup.3 denotes hydrogen or C.sub.1 - to C.sub.4 -alkyl and the ring D is saturated.

Abstract: An improved process for the preparation of 2,6-dichloro-5-fluoronicotinoyl chloride is described where a 2,6-dihydroxy-5-fluoronicotinic acid ester is converted in one step using phosphorus oxychloride and a lithium reagent to 2,6-dichloro-5-fluoronicotinoyl chloride and subsequent basic hydrolysis affords 2,6-dichloro-5-fluoronicotinic acid.

Abstract: The present invention relates to a process of converting partially purified taxane mixtures into Baccatin III. The process for the preparation of Baccatin III includes contacting a mixture containing at least one taxane compound having an ester linkage at the C-13 position with at least one borohydride reducing salt in a reaction solvent in the present of a Lewis acid.

Abstract: A process for separating and recovering an organic phase (e.g., fluorocarbons such as chlorofluorocarbons, hydrochlorofluorocarbons, hydrofluorocarbons and perfluorocarbons) from a feed stream of a mixture of fluorocarbons and hydrogen fluoride, wherein the mixture is characterized as forming at least one azeotrope or azeotrope-like composition involving at least one fluorocarbon and hydrogen fluoride, by passing the fluorocarbon/HF mixture feed stream through the feed side of a semipermeable membrane unit and then further separating a fluorocarbon-depleted hydrogen fluoride permeate stream and a fluorocarbon enriched residual stream exiting the membrane unit by conventional distillation. An essentially pure fluorocarbon phase and hydrogen fluoride phase are recovered from the distillation with the azeotrope or azeotrope-like distillate being recycled to the inlet of the semipermeable membrane unit.

Abstract: The present invention is directed toward a process of treating crude dinitroaniline with an aqueous sulfite solution as a method of stabilizing the herbicide against formation of nitrosamines and of reducing impurities therein.

Abstract: A continuous process for the preparation of a bisazo pigment mixture of at least two different bisazo pigments of the general formula ##STR1## wherein R.sub.1 and R.sub.2 each may be independent of themselves and are each independently of one another hydrogen, chloro, methyl or methoxy, which bisazo pigments differ from each other in at least one of the substituents R.sub.1 or R.sub.2, by simultaneously coupling a bisdiazotized diaminodiphenyl (A) of formula ##STR2## and a mixture (B) of two coupling components of formula ##STR3## wherein R.sub.1 and R.sub.2 are each independently of the other hydrogen, chloro, methyl or methoxy which coupling components differ from each other at least one of the substituents R.sub.1 or R.sub.

Abstract: A bis(organothio) alkane, such as 1,2-bis(methylthio) hexane, is synthesized by reacting an alkene, such as 1-hexene, with an excess amount of a disulfide thiolating agent, such as dimethyl disulfide, in the presence of a catalytic amount of a catalyst, such as a boron trifluoride dialkyl etherate. The reaction can be carried out at from about 20.degree. to about 150.degree. C. and under a pressure of from about 0 to 20 atms. The bis(organothio) alkane is useful in ore flotation process as a flotation agent for ores containing metal sulfide minerals.

Abstract: The present invention is directed toward the preparation of novel polysubstituted fullerenes. The method of forming polysubstituted fullerenes comprises contacting a fullerene with an electrophilic reagent selected from the group consisting of nitronium ion and organic peracid, provided that when the electrophilic reagent is nitronium ion, the fullerene is subsequently contacted with a nucleophilic reagent.

Abstract: Fertilizer/pesticide compositions are disclosed which include a fertilizer component and an active component. The fertilizer component includes plant nutrients, and the active component includes an active material, such as a pesticide, which has a desired effect on plant growth or health when released to the plant over an extended period of time. In a preferred form, the fertilizer component is admixed with the active component and a binder and compressed to form a briquette in which the fertilizer component occludes the active component. The briquette is essentially free of significant quantities of materials which have a high solubility in water. Thus, when a briquette is placed in the soil, it releases nutrients and the active material into the soil over an extended period of time for delivery to the plant. A method of treating plants with such fertilizer/pesticide compositions is also disclosed.

Abstract: Hepatobiliary magnetic resonance imaging of a human or animal subject is enhanced by enterally administering to the subject an effective amount of a lipophilic contrast enhancing agent. Representative contrast enhancing agents include manganese mesoporphyrin, manganese deuteroporphyrin, manganese pheophorbide and manganese pyrophenophoribide, and, when administered orally, an enteric delivery agent.

Abstract: An improved process for preparing a polyether polyol of reduced scorching properties comprising buffering of the alkaline polyether polyol before heating to remove water, and the use of said polyether polyol to prepare flexible foam slabstocks.

Abstract: Polyarylene sulfide having a much reduced content of impurities is prepared by reacting an aromatic polyhalide with an alkali metal sulfide in the presence of a polar organic solvent and subjecting the resulting polyarylene sulfide subsequently to an acid treatment, filtration through a screen having a mesh size of 50-100 .mu., and washing with, successively, the same solvent as used in the preparation of the polymer, water, an organic or inorganic acid, and water. The resulting polyarylene sulfide has a sodium content of less than 20 ppm.

Abstract: An improved process for the preparation of fluoxetine. The invention is concerned with an improved process for the preparation of the antidepressant, fluoxetine hydrochloride, or N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine hydrochloride, by simultaneous debenzylation and catalytic hydrogenation of 2-benzoyl-1-(N-benzyl-N-methyl)ethylamine base with the aid of Pd/C, Pt/C or Pd-Pt/C at a hydrogen pressure of 5 bar at 50.degree. C. with ethyl acetate as a solvent to obtain 1-phenyl-3-(N-methylamino)-propan-1-ol. This compound is then selectively etherified with 1-chloro-4-trifluoromethylbenzene in N-methylpyrrolidone at 80.degree. C. in the presence of potassium t-butoxide to form N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine, or fluoxetine base, which is transformed in a known manner to fluoxetine hydrochloride, or N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine hydrochloride. The yield of fluoxetine hydrochloride is 85-87% of the theoretical.

Abstract: A compound of the formula: ##STR1## wherein: X, Y and Z, independently, are hydrogen, halogen, hydroxy, nitro, cyano, carboxyl, trifluoromethyl, phenyl, amino, mono and di-alkylamino, C.sub.1 -C.sub.12 alkyl or C.sub.1 -C.sub.12 alkoxy; R.sub.1 is hydrogen, C.sub.1 -C.sub.18 saturated or unsaturated alkyl, cycloalkyl, phenyl, benzyl or substituted benzyl where the substituents are C.sub.1 -C.sub.12 alkyl, or C.sub.1 -C.sub.12 alkoxy; and R.sub.2 is represented by 2. ##STR2## in which X, Y, and Z are defined above; or a pharmaceutically acceptable salt thereof.

Abstract: Synthesis gas, hydrogen and carbon monixide, as produced in a fluid-bed or spouted-bed process by reacting methane or a lower alkane with steam and oxygen in the presence of essentially non-catalytic, heat carrying solids with periodic addition of a steam-reforming catalyst for maintaining a level of activity sufficient within 250.degree. F. of the approach to equilibrium.

Abstract: Aminomethanephosphonic acid aryl esters of the formula ##STR1## in which R.sup.1 is an aromatic radical and R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 independently of one another represent hydrogen atoms, ##STR2## groups, an optionally substituted C.sub.1-10 alkyl radical or an optionally substituted aromatic ring, or salts thereof.These aminomethanephosphonic acid aryl esters are useful as flameproofing agents in foams, thermoplastics and thermosets and as a crosslinking component in oligo-and polycondensates based on monomers containing hydroxy groups.