Patents Examined by Michael D'Angelo
  • Systems and methods for processing sensor data
    Patent number: 8417312
    Abstract: Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided.
    Type: Grant
    Filed: October 24, 2008
    Date of Patent: April 9, 2013
    Assignee: DexCom, Inc.
    Inventors: Apurv Ullas Kamath, J. Michael Dobbles, Aarthi Mahalingam
  • Fluid component analysis system and method for glucose monitoring and control
    Patent number: 8417311
    Abstract: Disclosed are methods and apparatuses for determining analyte concentration in a sample such as bodily fluid. Systems and methods disclosed herein can also include a treatment dosing system to infuse or inject a treatment dose (e.g. insulin, dextrose, etc.) and provide glycemic control. The dose of the treatment drug may be based on the patient's calculated sensitivity to treatment dosing, for example. The dose of the treatment drug may be based on the concentration of the analyte or the average value for the concentration of the analyte and/or the rate of change of the value of the concentration of the analyte. Delivery of the treatment drug can be cut off if the determined analyte concentration indicates that continued delivery would be harmful to the patient.
    Type: Grant
    Filed: September 14, 2009
    Date of Patent: April 9, 2013
    Assignee: Optiscan Biomedical Corporation
    Inventor: Peter Rule
  • Detection of hypovolemia using implantable medical device
    Patent number: 8414497
    Abstract: An implantable medical device receives a physiological signal indicative of circulatory blood volume and detects hypovolemia from that physiological signal. In one embodiment, an implantable pulmonary artery pressure (PAP) senses a PAP signal, and the implantable medical device detects hypovolemia from the PAP signal.
    Type: Grant
    Filed: July 11, 2012
    Date of Patent: April 9, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventor: Jeffrey E. Stahmann
  • Method and system for monitoring physiological conditions
    Patent number: 8401631
    Abstract: A method for providing an indication of a state of awareness for a patient, includes the steps of arranging data of an EEG and EMG power spectrogram to provide power versus frequency in a log-log arrangement; calculating a first best-fit line for a lower frequency region of the EEG power spectrogram; calculating at least a second best-fit line for a higher frequency region of the EEG power spectrogram. The display of these lines is augmented by displaying a template that identifies different regions on the display that help confirm the state of the patient. Secondly, the time domain EEG signals can be filtered and displayed such that different frequency bands can be simultaneously displayed or a single frequency band can be displayed according to different time scales.
    Type: Grant
    Filed: October 18, 2010
    Date of Patent: March 19, 2013
    Inventor: Christopher Scheib
  • Analyte sensor
    Patent number: 8396528
    Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.
    Type: Grant
    Filed: March 25, 2008
    Date of Patent: March 12, 2013
    Assignee: DEXCOM, Inc.
    Inventors: Apurv Ullas Kamath, Peter C. Simpson, Mark Brister
  • System and methods for processing analyte sensor data
    Patent number: 8394021
    Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
    Type: Grant
    Filed: October 1, 2007
    Date of Patent: March 12, 2013
    Assignee: DexCom, Inc.
    Inventors: Paul V. Goode, James H. Brauker, Apurv U. Kamath
  • Display of target cardiac flow based on cardiac index calculation
    Patent number: 8382678
    Abstract: User interfaces for medical perfusion systems that provide oxygenation, filtering, and recirculation of blood in connection with various medical procedures are provided. In particular, methods of displaying and communicating a desired target flow rate and cardiac index during cardiopulmonary bypass surgeries are provided.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: February 26, 2013
    Assignee: Medtronic, Inc.
    Inventors: Brian J. Steffens, Mark Salzwedel, Mark G. Bearss, Keith D. Rohde
  • Calibration techniques for a continuous analyte sensor
    Patent number: 8386004
    Abstract: Disclosed herein are systems and methods for calibrating a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes one or more electrodes to measure an additional analyte. Such measurements may provide a baseline or sensitivity measurement for use in calibrating the sensor. Furthermore, baseline and/or sensitivity measurements may be used to trigger events such as digital filtering of data or suspending display of data.
    Type: Grant
    Filed: September 7, 2011
    Date of Patent: February 26, 2013
    Assignee: DexCom, Inc.
    Inventors: Apurv Ullas Kamath, Peter C. Simpson, James H. Brauker, Paul V. Goode, Jr.
  • Anchored implantable pressure monitor
    Patent number: 8382677
    Abstract: An anchored implantable pressure monitor.
    Type: Grant
    Filed: April 25, 2011
    Date of Patent: February 26, 2013
    Assignee: Vital Sensors Holding Company, Inc.
    Inventors: Volker Bodecker, Max Georg Ostermeier, Stefan Meyer, Axel Niemeyer
  • Implantable pressure monitor
    Patent number: 8376953
    Abstract: An implantable pressure monitor.
    Type: Grant
    Filed: April 25, 2011
    Date of Patent: February 19, 2013
    Assignee: Vital Sensors Holding Company, Inc.
    Inventors: Volker Bodecker, Max Georg Ostermeier, Stefan Meyer, Axel Niemeyer
  • Signal processing for continuous analyte sensor
    Patent number: 8374667
    Abstract: Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.
    Type: Grant
    Filed: October 16, 2008
    Date of Patent: February 12, 2013
    Assignee: DexCom, Inc.
    Inventors: James H. Brauker, Victoria E. Carr-Brendel, Paul V. Goode, Apurv Ullas Kamath, James Patrick Thrower, Ben Xavier
  • System and method for generating a trend parameter based on respiration rate distribution
    Patent number: 8372012
    Abstract: Systems and methods provide for assessing the heart failure status of a patient and, more particularly, to generating a trend parameter based on a distribution of the patient's respiration rate. Systems and methods provide for detecting, using an implantable device or a patient-external device, patient respiration and computing a respiration rate based on the detected patient respiration. A distribution of the respiration rate is calculated, and a trend parameter based on the respiration rate distribution is generated. The trend parameter is indicative of a patient's heart failure status. An output signal indicative of the patient's heart failure status may be generated based on the trend parameter.
    Type: Grant
    Filed: April 28, 2010
    Date of Patent: February 12, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Viktoria Averina, Yi Zhang, Yousufali Dalal
  • Body fluid sampling device
    Patent number: 8369918
    Abstract: Body fluid sampling device comprising a sampling element having a fluid pathway (11) for receiving body fluid, at least a portion of the fluid pathway is open to the environment and further comprising a fluid receiving means (40) being spaced from the fluid pathway so that fluid in the pathway will not contact the fluid receiving means initially. The fluid receiving means has two or more test zones (45) for performing analytical reactions. Fluid from the channel is contacted with the fluid receiving means either by bringing the fluid receiving means and the fluid into mechanical contact or by electrically transporting fluid from the channel onto the fluid receiving means.
    Type: Grant
    Filed: June 23, 2011
    Date of Patent: February 5, 2013
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Irio G. Calasso, Patrick Griss, Emad Sarofim, Rainer Jaeggi, Uwe Kraemer, David Hasker, Volker Zimmer
  • Systems and methods for processing sensor data
    Patent number: 8369919
    Abstract: Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided.
    Type: Grant
    Filed: October 24, 2008
    Date of Patent: February 5, 2013
    Assignee: DexCom, Inc.
    Inventors: Apurv Ullas Kamath, Paul V. Goode, James H. Brauker, James P. Thrower
  • Apnea type determining apparatus and method
    Patent number: 8360983
    Abstract: An apnea classification system provides for apnea monitoring and differentiation based on several sleep apnea related parameters for diagnostic and therapeutic purposes. Monitoring of such sleep apnea related parameters allows the apnea classification system to differentiate among the different types of apnea and hypopnea and to identify an occurrence of periodic respiration. This information may then be used to determine the best method of therapy, or adjust current therapy parameters to more effectively treat a subject.
    Type: Grant
    Filed: June 29, 2011
    Date of Patent: January 29, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Abhilash Patangay, Yachuan Pu
  • Non-contact and passive measurement of arterial pulse through thermal IR imaging, and analysis of thermal IR imagery
    Patent number: 8360986
    Abstract: A non-contact, passive method for measurement of arterial pulse from areas such as the major superficial arteries of the body through analysis of thermal IR images acquired by passive thermal IR imaging sensors, and through the modeling of the pulsatile nature of the blood flow and arterial pulse propagation in the circulatory system. The method is automatic and does not need operator input. The output waveform readily contains the information on heart rate, cardiac interbeat intervals, heart-rate variability and other features inherent in arterial pulse.
    Type: Grant
    Filed: July 2, 2007
    Date of Patent: January 29, 2013
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Aly A. Farag, Sergey Y. Chekmenev
  • Microelectronic biosensor plug
    Patent number: 8364232
    Abstract: A plug capable of providing information relating to a physical or chemical property of a body fluid, or the presence or amount of a molecular component therein in a living organism is disclosed. Specifically, one embodiment plug is capable of being inserted into a portion of a human eyelid in order to provide information relating to tear fluid is disclosed. This embodiment plug includes a body having a passage which allows for the natural flow of tear fluid therethrough. In addition, a sensing mechanism is provided which is capable of measuring, for example, glucose levels in the body of a patient through the analysis of the tear fluid. Such plug may further be designed so as to double as a punctal plug useful in preventing dry eye. Methods of utilizing and implanting such plugs are also disclosed.
    Type: Grant
    Filed: July 28, 2011
    Date of Patent: January 29, 2013
    Inventor: Robin A. Felder
  • Apparatus and method for sensor deployment and fixation
    Patent number: 8355777
    Abstract: A delivery system for fixation of an implant assembly having an intracorporeal device at a deployment site using an anchoring structure. This invention provides an implant assembly having an anchor for fixation within a vessel. The anchoring structure adapted to be delivered via a catheter.
    Type: Grant
    Filed: September 19, 2011
    Date of Patent: January 15, 2013
    Assignee: CardioMEMS, Inc.
    Inventors: Jason White, Kelly Tumlin
  • Apparatus and method for sensor deployment and fixation
    Patent number: 8353841
    Abstract: An implant assembly is implanted in vivo within a vascular system in the implant assembly has a diameter greater than a vessel and compliance characteristics such that, upon release, the implant assembly forms an interference fit is between the anchor structure and the vessel wall, thereby preventing further distal movement.
    Type: Grant
    Filed: November 1, 2011
    Date of Patent: January 15, 2013
    Assignee: CardioMEMS, Inc.
    Inventors: Jason White, Kelly Tumlin
  • System, method and device for aiding in the diagnosis of respiratory dysfunction
    Patent number: 8348853
    Abstract: A system and method for aiding in the diagnosis of a respiratory dysfunction is described. More particularly, a system and method for aiding in the diagnosis of one or more pulmonary embolisms is described. The system and method described herein include a plurality of sensors, a thermal control system, and a controller means coupled to the plurality of sensors and the thermal control system for aiding in the diagnosis of a respiratory dysfunction.
    Type: Grant
    Filed: February 6, 2006
    Date of Patent: January 8, 2013
    Assignee: DEKA Products Limited Partnership
    Inventors: David E. Altobelli, Benjamin W. Jones, Jr., Derek G. Kane, Gregory R. Lanier, Jr., Paul R. Marquis, Eric M. Soederberg