Patents Examined by Natasha Patel
  • Patent number: 11224718
    Abstract: Representative embodiments of the present invention provide for novel, minimally invasive implantable devices and methods for targeted tissue drug delivery of cardiovascular drugs.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: January 18, 2022
    Assignee: Native Cardio, Inc.
    Inventors: Young D. Kim, Joseph V. Pergolizzi, Scot Johnson
  • Patent number: 11219759
    Abstract: A medical device kit includes a tunneling tool configured to form a tunnel through patient tissue for receiving an electrical stimulation lead. The tunneling tool includes a tunneling-tool body having an elongated shape with a proximal portion and a distal portion. The tunneling-tool body is formed from a material configured to be manually bent prior to insertion into patient tissue to conform to an anatomical contour through which the tunnel is to extend. A blunt tip is disposed at the distal portion. The blunt tip is configured to tunnel through patient tissue. A tunneling-tool suture-receiving element is disposed along the proximal portion of the tunneling-tool body. The tunneling-tool suture-receiving element is configured to receive a suture extendable along the tunnel formed by the tunneling tool.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: January 11, 2022
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Jacob B. Leven, Kevin Peng Wang, Rhys Wheatley
  • Patent number: 11219754
    Abstract: Apparatus includes a flexible intraventricular receptacle that assumes a first volume upon passage of fluid that is not blood into the receptacle and a second, smaller volume upon passage of the fluid out of the receptacle. An expandable extracardiac receptacle expands upon transfer of the fluid into the extracardiac receptacle from the intraventricular receptacle and contracts upon passage of the fluid out of the extracardiac receptacle. A transmyocardial conduit allows passage of the fluid between the intraventricular receptacle and the extracardiac receptacle responsively to a cardiac cycle. During ventricular systole, a volume of fluid is expelled from the intraventricular receptacle, through the conduit, and into the extracardiac receptacle, producing a corresponding decrease in a total volume of the ventricle during isovolumetric contraction of the ventricle. Other embodiments are also described.
    Type: Grant
    Filed: May 20, 2020
    Date of Patent: January 11, 2022
    Assignee: RAINBOW MEDICAL LTD.
    Inventor: Yossi Gross
  • Patent number: 11219763
    Abstract: The techniques of the disclosure describe example medical devices, systems, and methods for delivering stimulation therapy comprising a first set of a plurality of pulses having a first amplitude, and a second set of a plurality of pulses having a second amplitude greater than the first amplitude. The second amplitude is adjusted to an adjusted second amplitude based on second amplitude being less than or greater than activation threshold. The first amplitude is adjusted based on adjusted second amplitude, and therapy is delivered based at least one the adjusted first amplitude.
    Type: Grant
    Filed: October 5, 2017
    Date of Patent: January 11, 2022
    Assignee: MEDTRONIC, INC.
    Inventor: Nathan A. Torgerson
  • Patent number: 11213675
    Abstract: Anchoring devices for affixing an implanted lead at a target location in a patient are provided herein. Such anchoring devices include a helical body having a plurality of tines extending laterally outward from the lead when deployed that engage tissue to inhibit axial movement of the implanted lead. The plurality of tines are biased towards the laterally extended deployed configuration and fold inward towards the lead to a delivery configuration to facilitate delivery of the lead through a sheath. The tines may be angled in a proximal direction or in both proximal and distal directions and may include various features to assist in visualization and delivery of the lead.
    Type: Grant
    Filed: October 9, 2019
    Date of Patent: January 4, 2022
    Assignee: AXONICS, INC.
    Inventors: Henry Lee, Alexander Hwu
  • Patent number: 11202903
    Abstract: Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In certain embodiments, the self-righting article a tissue-interfacing components. In some embodiments, each tissue-interfacing component may comprise an electrically-conductive portion configured for electrical communication with tissue and an insulative portion configured to not be in electrical communication with tissue.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: December 21, 2021
    Assignees: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.
    Inventors: Robert S. Langer, Carlo Giovanni Traverso, Alex G. Abramson, David Dellal
  • Patent number: 11202601
    Abstract: This document discusses, among other things, systems and methods for monitoring a patient at risk of epilepsy. A system comprises a sensor circuit that senses from the patient at least first and second physiological or functional signals. A wellness detector circuit can detect an epileptic event using the sensed physiological or functional signals, or additionally classify the epileptic event into one of epileptic seizure types. The system can generate a wellness indicator based on a trend of the physiological or functional signal during the detected epileptic event. The wellness indicator indicates an impact of the detected epileptic event on the health status of the patient. The system includes an output unit configured to output the detection of the epileptic event or the wellness indicator to a user or a process.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: December 21, 2021
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: David J. Ternes, Pramodsingh Hirasingh Thakur, Qi An, Amy Jean Brisben, Stephen B. Ruble, Keith R. Maile
  • Patent number: 11202899
    Abstract: Described are systems and methods for administration of nitric oxide (NO) with use of left ventricular assists devices (LVADs), as well as systems and methods for monitoring the NO delivery devices and/or the LVAD.
    Type: Grant
    Filed: January 30, 2017
    Date of Patent: December 21, 2021
    Assignee: Mallinckrodt Pharmaceuticals Ireland Limited
    Inventors: Jim Potenziano, Douglas Alan Greene, Craig Flanagan
  • Patent number: 11198012
    Abstract: Programming a stimulator device to deliver a stimulation therapy at high-density parameter settings using a cathode-minimized electrode configuration determined to induce paresthesia over a patient pain pattern at low-density parameter settings.
    Type: Grant
    Filed: August 22, 2017
    Date of Patent: December 14, 2021
    Assignee: Medtronic, Inc.
    Inventor: Hector Cantua
  • Patent number: 11197998
    Abstract: Devices, systems and methods are disclosed that allow a patient to self-treat a medical condition, such as migraine headache, by electrical noninvasive stimulation of a vagus nerve. The system comprises a stimulator that is applied to the surface of the patient's neck. The device housing transmits data to a patient interface device such as a mobile phone or computer relating to the status of a stimulation session. The interface device in turn may communicate with a database contained within other computers, via a network or the internet. The system is designed to address problems that arise particularly during self-treatment, when a medical professional is not present.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: December 14, 2021
    Assignee: ELECTROCORE, INC.
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Patent number: 11185692
    Abstract: The present invention discloses a wireless and self-contained headset that delivers an electronic signal to a precise and self-locating position within bilateral conchae in both ears of a human user. The headset comprises an electronics housing that carries a specific waveform source. The waveform source generates the electronic signal, which is delivered simultaneously to both left and right ears of the human user. An array of silver electrodes housed within the bilateral earpieces cover with precision the location at the exact center of the relatively smooth plane of the conchae directly behind the external auditory meatus (ear opening/canal).
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: November 30, 2021
    Inventor: Emily Ireland
  • Patent number: 11185285
    Abstract: Mouth guard that includes a flexible printed circuit board encapsulated within a base member is provided. The flexible printed circuit board includes multiple separate stiff sections spaced apart from each other within the base member. One or more electronic devices are disposed within the base member. In particular, the one or more electronics are disposed on the base member.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: November 30, 2021
    Assignee: INTEL CORPORATION
    Inventors: Braxton Lathrop, Cody Gabriel, James Hall, Michael Rosen, Nathan Stebor, Philip Muse, Rita Brugarolas Brufau, Shea Dillon, Stephanie Moyerman, Steven Xing, Tyler Fetters
  • Patent number: 11185269
    Abstract: Optimizing psychiatric and physiologic monitoring of a patient having PTSD or anxiety-related mental health condition. According to an embodiment, one or more physiological variables are longitudinally measured; resting heart rate is measured from which a timeseries is constructed; outlier anomalous values are removed from the timeseries, it is de-trended and/or de-meaned; and a serial normal sinus rhythm beats (SDNN) and/or other parameters are determined. Fractal properties of the serial SDNN values are calculated, such as the Hurst exponent alpha via detrended fluctuation analysis (DFA) or spectral regression; and other measures of chaos and nonlinearity are calculated, such as the Shannon entropy of the SDNN or related timeseries. Where such measures indicate a statistically-significant transgression of a context-indexed reference range, a notification is provided to a case management clinician or caregiver so that appropriate additional evaluation and diagnosis and treatment may be undertaken.
    Type: Grant
    Filed: February 25, 2019
    Date of Patent: November 30, 2021
    Assignee: CERNER INNOVATION, INC.
    Inventor: Douglas S. McNair
  • Patent number: 11185239
    Abstract: A system for determining reference signatures for use in assisting identification of a body state in a biological subject, the system including at least one processing device that obtains reference data for each of a plurality of reference individuals, the reference data including at least one reference impedance indicator obtained by performing at least one impedance measurement on the reference individual, a body state indication indicative of any body states associated with the reference individual and characteristic data indicative of one or more physical characteristics of the reference individual and analyses the reference data to establish one or more reference signatures, each reference signature being indicative of at least one reference impedance indicator associated with a respective body state for respective physical characteristics.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: November 30, 2021
    Assignee: IMPEDIMED LIMITED
    Inventors: Richard Roland Carreon, Jack Gerald Cosentino
  • Patent number: 11179557
    Abstract: Modular mammalian body implantable fluid flow influencing device, comprising: docking unit having receiving surface, distal and proximal ends, proximal guide hole. Functional unit having docking surface shaped to mate with receiving surface, distal and proximal ends. Control wire extends from proximal end of functional unit then goes through guide hold then extends proximally away from docking unit. Functional and docking units are dimensioned and shaped to be deliverable to an implantation site via catheter. Functional unit has docked configuration in which docking surface mates with receiving surface of docking unit and undocked configuration in which docking surface is unmated with and spaced apart from receiving surface of docking unit. Functional unit moveable at implantation site between undocked and docked configurations via movement of control wire. Functional unit moveable into docked configuration by pulling control wire, and moveable from into undocked configuration by pushing control wire.
    Type: Grant
    Filed: May 4, 2020
    Date of Patent: November 23, 2021
    Assignee: PUZZLE MEDICAL DEVICES INC.
    Inventors: Gabriel Georges, Fran├žois Trudeau, Jade Doucet-Martineau
  • Patent number: 11172820
    Abstract: A physiological information processing method includes: acquiring electrocardiogram data from a subject; acquiring pulse wave data from the subject; measuring a plurality of RR intervals based on the acquired electrocardiogram data; measuring a plurality of pulse wave transit times based on the acquired electrocardiogram data and the acquired pulse wave data; calculating, based on the measured RR intervals and the measured pulse wave transit times during a given time period, a parameter related to correlation between the measured RR intervals and the measured pulse wave transit times; and outputting the calculated parameter.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: November 16, 2021
    Assignee: NIHON KOHDEN CORPORATION
    Inventors: Yoshihiro Sugo, Yoshiharu Harada, Tomoyuki Sakai, Mami Sakai
  • Patent number: 11160500
    Abstract: Disclosed herein is a system for determining a subject's stress condition. The system includes a stress test unit configured for: receiving features defining the subject and physiological signals sensed from the subject when performing a relaxation and a stressful test task; extracting normalization parameters from the physiological signals; and identifying stress-responsive physiological features. The system also includes a storage unit configured for: storing a plurality of stress models; and storing the subject's features, normalization parameters, and the stress-responsive physiological features.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: November 2, 2021
    Assignees: IMEC vzw, Katholieke Universiteit Leuven, KU LEUVEN R&D
    Inventors: Elena Smets, Emmanuel Rios Velazquez, Giuseppina Schiavone, Walter De Raedt, Christiaan Van Hoof
  • Patent number: 11147499
    Abstract: A method of determining atrial fibrillation includes determining if a patient's pulse beats form an irregular pattern. If so, presence of an irregular pulse is indicated to a patient and, an electrocardiogram is obtained for determining atrial fibrillation. Initially, a pulse is detected at regular time intervals from a first appendage when motionless, using a pulse detector and pulse rhythms from a succession of time intervals, each corresponding to a respective interval of time between successive pulse beats of a sequence of the pulse beats. Then, a second appendage makes contact with an electrically conductive unit, and electrocardiogram signals are detected simultaneously with pulse rhythms while the first appendage is motionless and both appendages are relaxed. The signals are then analyzed to determine whether, in combination, they are indicative of atrial fibrillation.
    Type: Grant
    Filed: February 25, 2019
    Date of Patent: October 19, 2021
    Inventor: Joseph Wiesel
  • Patent number: 11141185
    Abstract: A device for intrabody surgery comprises a cutting arrangement rotatable by a hollow driveshaft, which is formed by a hollow front cutting region and a rear region. The front region includes multiple longitudinal drilling sections interconnected by transversely oriented cutting blade sections. The drilling sections are positioned at an angle to each other defining in combination with the cutting blades a conically shaped grid formation having a hollow internal cavity. The grid formation defines a plurality of ports between the drilling sections and the blades. A low-pressure zone is formed within the hollow internal cavity, wherein cut occlusion materials are aspired by the low-pressure zone through the plurality of ports into the hollow internal cavity for further evacuation from the cutting arrangement.
    Type: Grant
    Filed: May 8, 2019
    Date of Patent: October 12, 2021
    Inventor: Pavel V. Efremkin
  • Patent number: 11129549
    Abstract: The present invention relates to a device (20) for detection of a vital signs related risk score (111) for a bed fall risk of an individual (2), the device (20) comprising a first port (3) for obtaining vital signs data (140) related to a vital sign of the individual (2) and a vital signs processing unit (9) for obtaining and processing the vital signs data (140) to generate a vital signs related risk score (111) indicating the bed fall risk of the individual (2) by detecting at least one risk factor from the vital signs data (140) and computing the vital signs risk score (111) from the at least one risk factor.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: September 28, 2021
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Mirela Alina Weffers-Albu, Achim Gerhard Rolf Koerber