Abstract: A device according to the present disclosure comprises an intraocular prosthetic. In some embodiments, the device comprises a lens portion and a plurality of arms that radiate outward from the lens portion. The lens portion can comprise a central ring used to hold an intraocular lens. Each arm can comprise a foot plate which allows the device to push out distally against a ciliary body. Among other things, an intraocular device according to the present disclosure can be useful in correction of aphakia, restoration of accommodation, and treatment of glaucoma.

Abstract: Described herein are implant loading and delivery systems for treating heart failure. An implant loading system may include a funnel having a flared first end and a second end, such that the flared first end is configured for receiving and collapsing the expandable implant, and a sleeve removably coupled to the second end of the funnel and configured to transfer the expandable implant to a guide catheter. The expandable device may have a foot for contacting a first interior wall portion of a heart, a support frame including a plurality of radially expandable struts, and a membrane coupled to the support frame. The expandable device may be coupled to a delivery catheter. An expansion member coupled to a distal end of the delivery catheter may apply pressure to the support frame of the expandable device to move the expandable device from a collapsed configuration to an expanded deployed configuration.

Abstract: A compressible and expandable stent assembly for implantation in a body lumen such as a mitral valve, the stent assembly including at least one stent barrel that is shaped and sized so that it allows for normal operation of adjacent heart structures. One or more stent barrels can be included in the stent assembly, where one or more of the stent barrels can include a cylinder with tapered edge.

Abstract: The present technology is a prosthetic heart valve device, and related systems and methods, for treating a native valve of a human heart having a native annulus and native leaflets. One embodiment comprises a valve support, a prosthetic valve assembly within the valve support, and an anchoring member having an upstream portion and a downstream portion. The device further includes an extension member coupled to the fixation frame and extending radially outward therefrom. The extension member includes a plurality of wires, at least a portion of which include an inner core surrounded by an outer material. The wires include a plurality of recesses extending through at least a portion of the thickness of the outer material, and a therapeutic agent in the recesses for delivery to the anatomy when the prosthetic heart valve device is positioned at a native annulus.

Abstract: A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the frame attached thereto. The frame may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes an integrated handle shaft and balloon catheter. A valve holder is stored with the heart valve and the handle shaft easily attaches thereto to improve valve preparation steps.

Abstract: The disclosure relates to heart valve prostheses with the reduced need of pacemaker implantation and improved means for positioning the replacement heart valve.

Abstract: A stent with an improved anti-slip function. The stent includes: a cylindrical stent including a plurality of openings formed by weaving wires, and a plurality of peaks, the cylindrical stent being subjected to heat treatment, wherein the cylindrical stent has a PTFE-first artificial blood vessel layer being in entire contact with an inner surface thereof, and a plurality of PTFE-second artificial blood vessel layers being in partial contact with an outer surface thereof, and the first and second artificial blood vessel layers are heat-fused together to encompass the cylindrical stent, thereby forming a plurality of first sections having a plurality of openings obstructed and a plurality of seconds sections having the plurality of openings remaining unobstructed, wherein the first sections are inserted into a lesion while pressing against the lesion, thereby being caught in the lesion, and the second sections are caught in the lesion meshed with the openings.

Abstract: A stent delivery system includes an inner elongate shaft including a proximal portion, a distal portion, at least one lumen extending at least partially therethrough, and a stent receiving portion on the distal portion of the elongate shaft. An outer elongate shaft including a proximal portion, a distal portion, and first, second, and third lumens. A stent is positioned on the stent receiving portion of the elongate shaft, the stent having a first configuration and a second configuration. A proximal constraining arrangement is engaged with a proximal end of the stent. A distal constraining arrangement is engaged with a distal end of the stent. The first proximal constraining member is positioned within the first lumen of the outer elongate shaft, the second proximal constraining member is positioned within the second lumen of the outer elongate shaft, and the distal constraining arrangement is positioned within the inner elongate shaft.

Abstract: This invention provides a stent-graft that has both shape-maintainability and flexibility, and when implanted in a living body, the stent-graft performs its intended functions for a considerably long period of time relative to conventional stent-grafts, without causing conflict. The stent-graft comprises a stent comprising multiple elastic rings and a graft. An auxiliary elastic wire whose rigidity is lower than that of the stent is arranged at the end-part of the graft, and the auxiliary elastic wire is connected to the multiple elastic rings at the opening part.

Abstract: The aim of the invention is to ensure a secure support and/or a secure transport of a graft (4) or an implant. This is achieved by a device for supporting and transporting a graft (4) or implant, comprising a container (2) which can be filled with a medium (1), preferably a nutrient medium, and a receiving device (3) which can be arranged in the container (2) for the graft (4) or implant. The receiving device (3) has a receiving chamber (5) for the graft (4) or implant and two passages (6, 7) which lead to the receiving chamber (5), at least one of said passages (6, 7) being dimensioned for introducing and/or removing the graft (4) or implant into or out of the receiving chamber (5). The device also comprises a respective closure device (8, 9) for each of the two passages (6, 7), at least one of the closure devices (8, 9) being permeable for the medium (1). The invention further relates to a corresponding receiving device (3) and to a set comprising a corresponding device.

Abstract: A prosthetic system that includes a prosthetic implant and a support structure secured to an inner surface of a cavity of a bone is disclosed. The support structure defines a channel that extends through the length of the support structure. The prosthetic implant is received in the channel, and a portion of the prosthetic implant is secured to an inner surface of the support structure by an adhesive. The support structure may comprise a pair of partially hemispherical components arranged in spaced apart relationship thereby defining the channel between the pair of components.

Abstract: A method of mixing and delivering a substance to a bone includes providing a compressible tube having a reservoir and using a mixing apparatus to mix a particulate solid and a mixing liquid to form the substance within the reservoir of the compressible tube. The method further includes using a compressing device to move the substance through an exit port in the compressible tube for delivery to the bone. The compressing device may be positioned on the compressible tube and the method may further include moving the compressing device along the compressible tube to empty the substance from the compressible tube. The substance may be a bone void filler, and the substance may be delivered from the exit port in the tube through a delivery apparatus, such as a cannula, to a target portion of the anatomy.

Abstract: An example medical device for treating a body lumen is disclosed. The medical device includes an expandable scaffold positionable within a body lumen wherein the body lumen has an inner surface. The medical device also includes a support member extending circumferentially around and attached to an outer surface of the expandable scaffold. The support member is configured to be positioned between the outer surface of the expandable scaffold and the inner surface of the body lumen and at least a portion of the support member is configured to shift relative to the inner surface of the body lumen. Further, shifting the support member shifts the scaffold longitudinally from a first position within the body lumen to a second position within the body lumen with the scaffold in an expanded state to accommodate peristalsis.

Abstract: A prosthetic system that includes a prosthetic implant and a support structure secured to an inner surface of a cavity of a bone is disclosed. The support structure defines a channel that extends through the length of the support structure. The prosthetic implant is received in the channel, and a portion of the prosthetic implant is secured to an inner surface of the support structure by an adhesive. The support structure may comprise a pair of partially hemispherical components arranged in spaced apart relationship thereby defining the channel between the pair of components.

Abstract: A prosthetic valve assembly for implantation in a patient's circulatory system includes a stent, a valve member coupled to the stent and defining a preferred landing zone relative to anatomical structures in the patient's circulatory system, and at least one marker positioned in a predetermined relationship relative to the landing zone of the valve member, the marker being visually distinguishable from the stent using an imaging technique. By observing the marker, the prosthetic valve assembly may be implanted in the patient so that certain ones of the anatomical structures lie within the landing zone.

Abstract: Described herein are intraocular lenses and methods of implantation. In one aspect, the lens includes a shape changing optical element; a force translation element having a first end region coupled to the optical element and a second end region extending towards a ciliary structure, and an attachment portion coupled to the second end region of the force translation element and configured to contact the ciliary structure. The force translation element is configured to functionally transmit movements of the ciliary structure into a force exerted upon the optical element to effect an accommodating and a disaccommodating change of the optical element.

Abstract: A degradable iron-based alloy stent comprises an iron-based alloy substrate and a degradable polymer in contact with the surface of the substrate. The weight-average molecular weight of the degradable polymer is in the range of [1, 100]*104, and the polydispersity index of the degradable polymer is in the range of (1.0, 50]. The degradable polymer is selected from a degradable polyamino acid that can generate an acidic amino acid after degradation; or a mixture of the degradable polyamino acid and a degradable polyester, or a copolymer of monomers of the two; or a mixture of the degradable polyamino acid and a degradable polymer that does not generate acidic products after degradation, or a copolymer of the monomers of the two; or a mixture of the degradable polyamino acid, the degradable polyester and the degradable polymer that does not generate acidic products after degradation, or a copolymer of monomers of the three, or a mixture of a copolymer of monomers of any two of the three with the remaining one.

Abstract: An intraocular implant device for restoring, augmenting, or improving vision of a user, the implant including an intraocular implant body shaped for positioning inside a lens chamber of an eye, the body having an anterior side facing the cornea of the eye, and a posterior side facing the retina of the eye; a photoelectric sensor disposed on the anterior side of the body; wherein the photoelectric sensor is operable to receive incident light through the cornea and to convert the received light into electrical energy for use with one or more circuit components disposed on the body, and wherein the photoelectric sensor is nearly simultaneously operable to convert the received light into image data. The ocular implant device may include a projector for projecting the image data onto the retina of a user. The ocular implant may include a wireless receiver for receiving image data transmissions from an external source.

Abstract: A hybrid stent includes multiple main cells aligned in a spiral shape and including multiple first link units which are aligned diagonally and spaced at a predetermined distance from each other and multiple second link units which connect adjacent first link units among the multiple first link units and are spaced at a predetermined distance from each other, and one or more open cells adjacent to the multiple main cells in a longitudinal direction and aligned in a spiral shape.

Abstract: An intraocular implant device is operable in augmented reality and virtual reality configurations. The intraocular implant device includes an intraocular implant body shaped for positioning inside a lens chamber in an eye. The intraocular implant body has an anterior side facing the cornea of the eye and a posterior side facing the retina of the eye. A photoelectric sensor is disposed on the anterior side of the intraocular implant body. The photoelectric sensor is operable to receive natural, optimized or enhanced incident light through the cornea and to convert the received light into electrical energy for use with one or more circuit components disposed on the intraocular implant body.