Patents Examined by Paul B. Prebilic
  • Prosthetic heart valve and endoprosthesis comprising a prosthetic heart valve and a stent
    Patent number: 10603164
    Abstract: The invention relates to a prosthetic heart valve (100) for an endoprosthesis (1) used in the treatment of a stenotic cardiac valve and/or a cardiac valve insufficiency. The prosthetic heart valve (100) comprises of a plurality of leaflets (102), which consist of a natural and/or synthetic material and have a first opened position for opening the heart chamber and a second closed position for closing the heart chamber, the leaflets (102) being able to switch between their first and second position in response to the blood flow through the heart.
    Type: Grant
    Filed: July 25, 2017
    Date of Patent: March 31, 2020
    Assignee: JenaValve Technology, Inc.
    Inventors: Michael J. Girard, Randy Lane, Arnulf Mayer
  • Biodegradable vascular grafts
    Patent number: 10603156
    Abstract: A vascular graft that includes a biodegradable polyester electrospun tubular core; a biodegradable polyester outer sheath surrounding the biodegradable polyester tubular core; and a biodegradable poly(lactide) copolymer adhesive composition (i) disposed between the polyester electrospun tubular core and the polyester outer sheath, (ii) disposed between the polyester electrospun tubular core and the polyester outer sheath and on an outer surface of the of the polyester outer sheath, (iii) or disposed on an outer surface of the polyester outer sheath.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: March 31, 2020
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Robert Andrew Allen, Chelsea Elizabeth Stowell, Yadong Wang
  • Stent anchoring system
    Patent number: 10603193
    Abstract: An illustrative stent may comprise an elongated tubular member having a first end and a second end and an intermediate region disposed therebetween. The elongated tubular member may include at least one barb attached thereto. The barb may be configured to be tucked under a filament of the stent during delivery of the stent and protrude radially from the stent, when the stent is deployed.
    Type: Grant
    Filed: November 8, 2017
    Date of Patent: March 31, 2020
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Martyn G. Folan, Martin Hynes, Damien V. Nolan, Enda Connaughton, Matthew Montague, Thomas M. Keating, Michael Walsh
  • Heart valve assemblies
    Patent number: 10595991
    Abstract: A heart valve assembly comprises a first prosthesis configured to expand from an unexpanded state to an expanded state at which the first annular prosthesis contacts native tissue of a body lumen. The heart valve assembly also comprises a second prosthesis comprising a valve, and a connection adapter that secures the second prosthesis to the first prosthesis, the connection adapter having a multi-lobed circumference.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: March 24, 2020
    Assignee: MEDTRONIC, INC.
    Inventors: Thomas J. Fogarty, Michael J. Drews, Neil Holmgren, D. Bruce Modesitt
  • Ophthalmic devices, system and methods that improve peripheral vision
    Patent number: 10588739
    Abstract: The present disclosure relates to devices, systems, and methods for improving or optimizing peripheral vision. In particular, methods are disclosed which include utilizing particular characteristics of the retina in improving or optimizing peripheral vision. Additionally, various IOL designs, as well as IOL implantation locations, are disclosed which improve or optimize peripheral vision.
    Type: Grant
    Filed: July 2, 2018
    Date of Patent: March 17, 2020
    Assignee: AMO GRONINGEN B.V.
    Inventors: Robert Rosen, Hendrik A. Weeber, Carmen Canovas Vidal, Marrie H. Van Der Mooren, Mihai State, Patricia Ann Piers, Aixa Alarcon Heredia
  • Methods of correcting vision
    Patent number: 10583041
    Abstract: Methods of correcting vision for presbyopia, including remodeling a stroma with a laser to create an intracorneal shape, where the corneal shape includes a central region with a thickness that is about 50 microns or less measured from an extension of a shape of a peripheral region of the corneal shape, wherein remodeling a portion of the stroma increases a curvature of a central portion of the anterior surface of the cornea with a central elevation change for near vision.
    Type: Grant
    Filed: January 10, 2017
    Date of Patent: March 10, 2020
    Assignee: RVO 2.0 Inc.
    Inventors: Keith Holliday, Alan Lang
  • Method of corneal transplantation or corneal inlay implantation with cross-linking
    Patent number: 10583221
    Abstract: A method of corneal implantation with cross-linking is disclosed herein. In one or more embodiments, the method includes the steps of: (i) cutting a circular implant from a donor cornea; (ii) cutting the circular implant into a plurality of constituent pieces; (iii) forming a small incision in a recipient cornea of an eye of a patient; (iv) forming a pocket in the recipient cornea of the eye of the patient, the pocket being accessible through the small incision in the recipient cornea, and the pocket being bounded entirely by stromal tissue of the cornea; and (v) inserting each of the plurality of constituent pieces of the implant into the pocket of the recipient cornea via the small incision, wherein the implant is cross-linked so as to prevent an immune response to the implant and/or rejection of the implant by the patient.
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: March 10, 2020
    Inventor: Gholam A. Peyman
  • Apparatus for supporting personalized coronary stents
    Patent number: 10568696
    Abstract: A method including generating a 3-D model of an unstenosed geometry of a blood vessel responsive to a 3-D model of an actual geometry of the blood vessel, establishing a parametric description of a stent that is expanded from a collapsed configuration to a final configuration that apposes the unstenosed geometry, developing a design for the stent by varying parameters of the parametric description responsive to a design heuristic that includes risk of stent strut breakage during a plastic deformation between the collapsed configuration and the final configuration, embodying the stent according to the design for the stent, inserting the stent into a blood vessel in its collapsed configuration, maneuvering the stent through the blood vessel to a stenosis, and expanding the stent to its final configuration.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: February 25, 2020
    Assignee: International Business Machines Corporation
    Inventors: Julia S. Baldauf, Darcy J. Beurle, Matthew Downton, Kerry J. Halupka, Stephen M. Moore, Christine Schieber
  • Personalized coronary stent methods
    Patent number: 10568697
    Abstract: A method including generating a 3-D model of an unstenosed geometry of a blood vessel responsive to a 3-D model of an actual geometry of the blood vessel, establishing a parametric description of a stent that is expanded from a collapsed configuration to a final configuration that apposes the unstenosed geometry, developing a design for the stent by varying parameters of the parametric description responsive to a design heuristic that includes risk of stent strut breakage during a plastic deformation between the collapsed configuration and the final configuration, embodying the stent according to the design for the stent, inserting the stent into a blood vessel in its collapsed configuration, maneuvering the stent through the blood vessel to a stenosis, and expanding the stent to its final configuration.
    Type: Grant
    Filed: December 31, 2017
    Date of Patent: February 25, 2020
    Assignee: International Business Machines Corporation
    Inventors: Julia S. Baldauf, Darcy J. Beurle, Matthew Downton, Kerry J. Halupka, Stephen M. Moore, Christine Schieber
  • Adjusting the apodization pattern for diffractive IOLs
    Patent number: 10568734
    Abstract: An ophthalmic device including an ophthalmic lens having anterior and posterior surfaces and at least one diffraction grating is described. The diffraction grating(s) are on the anterior and/or posterior surface(s). The diffraction grating(s) include zones. A first zone is at a first distance range from a center of the lens. A second zone is at a second distance range further from the center than the first distance range. A repeat zone is at a third distance range further from the center than the second distance range. The first zone includes echelette(s) having a first step height and a first radius of curvature. The second zone includes echelette(s) having a second step height and a second radius of curvature. The repeat zone includes echelette(s) having at least one of the first step height and the first radius of curvature.
    Type: Grant
    Filed: March 3, 2016
    Date of Patent: February 25, 2020
    Assignee: Novartis AG
    Inventor: Richard J. Mackool
  • Aortic implant method
    Patent number: 10568731
    Abstract: Apparatus and methods are described for regulating blood flow in an ascending aorta of a subject including inserting a device (20) into the ascending aorta. When in a deployed state, the device defines an inner surface (24) that defines a conduit (26) through the device, at least a portion (25) of the inner surface diverging, such that a cross-sectional area of the conduit at the downstream end (34) of the diverging portion is greater than a cross-sectional area of the conduit at the upstream end (30) of the diverging portion. The device is deployed within a longitudinal portion of the ascending aorta, such that blood flow through the portion of the ascending aorta, via any flow path other than through the conduit, is less than 20 percent of total blood flow through the portion of the ascending aorta. Other applications are also described.
    Type: Grant
    Filed: February 11, 2016
    Date of Patent: February 25, 2020
    Assignee: HEMODYNAMX-TECHNOLOGIES LTD.
    Inventors: Sagy Karavany, Tanhum Feld, Boaz Nishri
  • Systems, methods and devices for two-step delivery and implantation of prosthetic heart valve
    Patent number: 10561495
    Abstract: A two-step delivery method, system and device is disclosed comprising, in various embodiments, a self-expanding frame. A self-expanding frame is delivered and expanded within a heart chamber followed by delivery of a prosthetic valve comprising prosthetic valves thereon into the expanded self-expanding frame, which is in turn connected to a valve connection region defined on and by the delivered and expanded frame.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: February 18, 2020
    Assignee: 4C Medical Technologies, Inc.
    Inventor: Jeffrey W. Chambers
  • Anterior corneal shapes and methods of providing the shapes
    Patent number: 10555805
    Abstract: Methods of treating presbyopia of an eye. A corneal inlay is inserted within the cornea such that the central thickness of the corneal inlay is 3 to 7 times a central elevation change.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: February 11, 2020
    Assignee: RVO 2.0, Inc.
    Inventors: Alan Lang, Keith Holliday
  • Biocompatible biodegradable intraocular implant system
    Patent number: 10548766
    Abstract: Generally, an intraocular implant and methods for treating an ocular condition. As to certain embodiments, an intraocular biocompatible biodegradable implant (11) which can provide a biocompatible biodegradable material in the form of a flexible membrane (12) containing an active agent (24) which implanted between an intraocular lens (8) and the surface of the posterior capsule (5) of the eye (1)(4) inhibits migration of residual lens epithelial cells after cataract surgery by providing structural or pharmaceutical barriers to reduce posterior capsule (5) opacification of the eye (1)(4).
    Type: Grant
    Filed: September 19, 2016
    Date of Patent: February 4, 2020
    Assignee: INSIGHT INNOVATIONS, LLC
    Inventor: Kevin H. Cuevas
  • Intraocular lens with elastic mask
    Patent number: 10548717
    Abstract: Intraocular implants and methods of making intraocular implants are provided. The intraocular implant can include a lens body having a lens material and a mask having a mask material. The lens body can be secured to the mask. The mask material can include a modulus of elasticity that is greater than or equal to a modulus of elasticity of the lens material.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: February 4, 2020
    Assignee: AcuFocus, Inc.
    Inventors: R. Kyle Webb, Daniel David Siems, Adam C. Reboul, Patrick H. Benz, Bruce Arthur Christie
  • Flexible strain sensors
    Patent number: 10545015
    Abstract: In one embodiment, a flexible strain sensor includes a flexible polymeric substrate having a top surface and a layer of amorphous carbon formed on the top surface of the substrate.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: January 28, 2020
    Assignee: Board of Regents, The University of Texas System
    Inventors: Uday Tata, Smitha Rao, Jung-Chih Chiao
  • Ring used in a small pupil phacoemulsification procedure
    Patent number: 10537470
    Abstract: A ring that can maintain a pupil in an extended position during an ophthalmic procedure. The ring has a plurality of loops that capture iris tissue. The ring is configured to extend the pupil when iris tissue is inserted into each loop. An ophthalmic procedure such as phacoemulsification can then be performed on the patient. The ring has a center opening that provides a wide view of the ocular chamber during the procedure.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: January 21, 2020
    Inventor: Boris Malyugin
  • Implantation assembly for an iris-expanding device
    Patent number: 10537473
    Abstract: An iris-expanding device injector assembly is described. The iris-expanding device injector assembly has a handle, a slider and/or button coupled with the handle and configured to slide with respect to the handle, a cannula coupled with the handle, the cannula configured to slide in to and out from a holder containing an iris-expanding device, and a hook housed within the cannula.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: January 21, 2020
    Assignee: Microsurgical Technology, Inc.
    Inventors: Boris Malyugin, Vaclav Dusek, Lawrence Laks
  • Multifocal lens and method for producing same
    Patent number: 10524899
    Abstract: The invention relates to a multifocal lens (1), in particular an intraocular lens or contact lens, having a refractive focus (Fr) and a first and a second diffractive structure (6, 7) that at least partially overlap, said two diffractive structures (6, 7) being different. A first order focus (F1;1) of the first diffractive structure (6) coincides with a first order focus (F2,1) of the second diffractive structure (7). The invention further relates to a method for producing such a multifocal lens (1).
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: January 7, 2020
    Assignee: Rayner Intraocular Limited
    Inventors: Kirsten Lux, Nicole Plank, Wolfgang Brezna, Nikolaus Dragostinoff
  • System for mitral valve repair and replacement
    Patent number: 10517725
    Abstract: Systems for mitral valve repair are disclosed where one or more mitral valve interventional devices may be advanced intravascularly into the heart of a patient and deployed upon or along the mitral valve to stabilize the valve leaflets. The interventional device may also facilitate the placement or anchoring of a prosthetic mitral valve implant. The interventional device may generally comprise a distal set of arms pivotably and/or rotating coupled to a proximal set of arms which are also pivotably and/or rotating coupled. The distal set of arms may be advanced past the catheter opening to a subannular position (e.g., below the mitral valve) and reconfigured from a low-profile delivery configuration to a deployed securement configuration. The proximal arm members may then be deployed such that the distal and proximal arm members may grip the leaflets between the two sets of arms to stabilize the leaflets.
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: December 31, 2019
    Assignee: Twelve, Inc.
    Inventors: Hanson S. Gifford, III, James I. Fann, John Morriss, Mark Deem, Jeffry J. Grainger