Patents Examined by Paul D. Pyla
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Patent number: 11490631Abstract: An infant formula for preventing gastro-esophageal reflux is disclosed comprising whey protein and/or casein, a galactomannan thickener, and a fermented milk-derived product.Type: GrantFiled: March 18, 2020Date of Patent: November 8, 2022Assignee: N.V. NUTRICIAInventors: Marie Thomas, Francis Lecroix, Evan Abrahamse, Houkje Bouritius
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Patent number: 11434508Abstract: The invention relates to a process for the preparation of a fermentation product from ligno-cellulosic material, comprising the following steps: a) optionally pre-treatment of the ligno-cellulosic material; b) optionally washing of the optionally pre-treated ligno-cellulosic material; c) enzymatic hydrolysis of the optionally washed and/or optionally pre-treated ligno-cellulosic material using an enzyme composition comprising at least two cellulase and whereby the enzyme composition at least comprises GH61; d) whereby less than 7.5 mg enzyme composition/g glucan (on dry matter and enzyme as protein) or less than 3.0 mg enzyme composition/g feedstock (on dry matter and enzyme as protein) is used; and e) fermentation of the hydrolysed ligno-cellulosic material to produce a fermentation product; and f) optionally recovery of a fermentation product; wherein before and/or during the enzymatic hydrolysis oxygen is added to the ligno-cellulosic material.Type: GrantFiled: April 23, 2020Date of Patent: September 6, 2022Assignee: DSM IP ASSETS B.V.Inventors: Bertus Noordam, Michael Petrus Jozef Berkhout
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Patent number: 11434507Abstract: The invention relates to a process for the preparation of a sugar product from lignocellulosic material, comprising the following steps: a) optionally pre-treatment of the ligno-cellulosic material; b) optionally washing of the optionally pre-treated ligno-cellulosic material; c) enzymatic hydrolysis of the optionally washed and/or optionally pre-treated ligno-cellulosic material using an enzyme composition comprising at least two cellulase and whereby the enzyme composition at least comprises GH61; and d) optionally recovery of a sugar product; wherein during part of the time of the enzymatic hydrolysis, oxygen is added to the ligno-cellulosic material and during part of the time of the enzymatic hydrolysis less oxygen is added to the ligno-cellulosic material compared to the other part of the time of the enzymatic hydrolysis, preferably no oxygen is added to the ligno-cellulosic material.Type: GrantFiled: April 1, 2020Date of Patent: September 6, 2022Assignee: DSM IP ASSETS B.V.Inventors: Bertus Noordam, Michael Petrus Jozef Berkhout, Aida Hiseni
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Patent number: 11427844Abstract: The invention relates to a process for the preparation of a fermentation product from ligno-cellulosic material, comprising the following steps: a) optionally pre-treatment of the ligno-cellulosic material; b) optionally washing of the optionally pre-treated ligno-cellulosic material; c) enzymatic hydrolysis of the optionally washed and/or optionally pre-treated ligno-cellulosic material using an enzyme composition comprising at least two cellulase and whereby the enzyme composition at least comprises GH61; d) fermentation of the hydrolysed ligno-cellulosic material to produce a fermentation product; and e) optionally recovery of a fermentation product; wherein before and/or during the enzymatic hydrolysis oxygen is added to the ligno-cellulosic material.Type: GrantFiled: April 27, 2020Date of Patent: August 30, 2022Assignee: DSM IP ASSETS B.V.Inventor: Bertus Noordam
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Patent number: 11401535Abstract: The present invention refers to a cyclic process for the production of vanillin, including (a) adding a solution of ferulic acid or a salt thereof, to a solid structure containing immobilized microorganisms of the Actinomycetales group, (b) incubating the solid structure to carry out the biotransformation process, (c) recovering the solution obtained in step (b), and (d) repeating steps (a) to (c) by feeding a fresh solution of ferulic acid or a salt thereof.Type: GrantFiled: October 18, 2008Date of Patent: August 2, 2022Assignee: LABORATORIOS MINKAB, S.A. DE C.V.Inventors: Ali Asaff Torres, Mayra De La Torre Martinez, Antonino Berrondo Mir, Roberto Miguel Macias Ochoa
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Patent number: 11390924Abstract: The present invention relates to an assay for use in a method of determining the oral health status of a canine animal by identifying certain bacteria present or absent in a sample taken from the animal, and applying the information set out herein for each identified bacteria to statistical models in order to determine the oral health status of the animal.Type: GrantFiled: June 13, 2014Date of Patent: July 19, 2022Assignee: Mars, IncorporatedInventors: Stephen James Harris, Matthew Coates, Matthew Ronald Gibbs
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Patent number: 11298383Abstract: This disclosure relates generally to a microbial treatment for poultry. More particularly, the disclosure relates to a direct fed microbial composition including one or more lactic acid bacteria strains in combination with one or more Bacillus bacteria strains configured to inhibit gastrointestinal pathogens in a bird. A method of use is also disclosed herein.Type: GrantFiled: May 22, 2017Date of Patent: April 12, 2022Assignee: Church & Dwight Co., Inc.Inventors: Thomas Rehberger, Evan Hutchison, Alexandra Smith
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Patent number: 11274272Abstract: The invention relates to a method for a photochemical process, such as a photocatalytic and/or photosynthetic process, in particular for the culture and production or the hydroculture of microorganisms. A reaction medium (6) is conducted in a meandering manner in a reactor element (2) which is made of at least two upright and connected pipes (3) or chambers (13). Multiple reactor elements (2) are serially connected into a bio solar reactor (1), and a reaction medium (6) flow which is stress-free for the microorganisms is generated in the bio solar reactor (1) using hydrostatic pressure and level compensation. Inlet and outlet openings (4, 5) are arranged on the lower face (8) of each individual reactor element (2) on each of the outermost pipes (3) or chambers (13). The reaction medium (6) flows around all of the connections in the lower region, in particular the inlet opening (4), the outlet opening (5), and the introduction inlet (17).Type: GrantFiled: May 27, 2015Date of Patent: March 15, 2022Assignee: BECO INVEST B.V.Inventor: Franz Emminger
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Patent number: 11273188Abstract: Provided are gut microbes or cultures having anti-obesity efficacy and a pharmaceutical composition containing them. The gut microbes or cultures have anti-obesity efficacy by lowering fatty acid concentration of the gut fluid contents in a mammalian gastrointestinal tract for the prevention and treatment of obesity and obesity related diseases. This invention demonstrated that said gut microbes having anti-obesity efficacy by lowering fatty acid concentration of the gut fluid contents in the gastrointestinal tract of mammals have the anti-obesity efficacy as much as that of the representative anti-obesity drug, orlistat, without any side effects in animal experiments and clinical trials. Therefore, the gut microbes h can be used to develop universal anti-obesity drugs for obese patients, contributing greatly to the health of mankind.Type: GrantFiled: November 8, 2016Date of Patent: March 15, 2022Assignee: MICROBIOTICA GMBHInventors: Hyeon Jin Kim, Seong Tshool Hong, Jae Gak Yu
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Patent number: 11242502Abstract: The present invention discloses a low urea-producing and flavor-producing Wickerhamomyces anomalus strain and a use thereof in food production, falling within the fields of wine brewing and food safety. The Wickerhamomyces anomalus of the present invention is obtained by isolating from a liquor fermentation environment (Daqu), is named Wickerhamomyces anomalus CGMCC NO. 12416, and was deposited at China General Microbiological Culture Collection Center on May 6, 2016, with a deposit number of CGMCC NO. 12416. The strain of the present invention has the characteristics of low urea production, flavor production, and tolerance to ethanol and acids, is an excellent strain having a fermentation function, and can be used in brewed wine, distilled liquor and other food fields to ensure food safety.Type: GrantFiled: December 12, 2018Date of Patent: February 8, 2022Assignee: Jiangnan UniversityInventors: Yan Xu, Qun Wu
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Patent number: 11241030Abstract: The present invention relates to edible webs comprising microorganisms, such as probiotics. In particular, the present invention relates to an edible web having microorganisms, such as bacteria, probiotic bacteria, bacteriophages or viruses printed thereon, e.g. by the use of inkjet printing. In addition the invention relates to methods of producing such edible webs, to various products comprising the edible webs as well as to use of the edible webs comprising microorganisms.Type: GrantFiled: February 22, 2018Date of Patent: February 8, 2022Assignee: Societe des Produits Nestle S.A.Inventor: Martinas Kuslys
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Patent number: 11202759Abstract: The invention provides compositions and methods to form pores in situ within hydrogels following hydrogel injection. Pores formed in situ via degradation of sacrificial porogens within the surrounding hydrogel facilitate recruitment or release of cells. Disclosed herein is a material that is not initially porous, but which becomes macroporous over time.Type: GrantFiled: October 6, 2011Date of Patent: December 21, 2021Assignee: President and Fellows of Harvard CollegeInventors: Nathaniel D. Huebsch, Christopher M. Madl, Kangwon Lee, Maria M. Xu, David J. Mooney
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Patent number: 11193148Abstract: The present disclosure provides a method for extracting alpha-ketoglutarate and pyruvate simultaneously from microbial fermentation broth or enzyme transformation solution, which is related to the technical field of biological separation and extraction.Type: GrantFiled: July 19, 2017Date of Patent: December 7, 2021Assignee: Jiangnan UniversityInventors: Jingwen Zhou, Jian Chen, Weizhu Zeng, Guocheng Du, Fang Fang, Song Liu
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Patent number: 11162123Abstract: A reagent for glutamine synthetase reaction comprising a chelating agent and glutamine synthetase, and a reagent for quantification of ammonia comprising a chelating agent, ATP, glutamic acid, glutamine synthetase, glucose, an oxidized NAD compound, ADP-dependent hexokinase, and glucose-6-phosphate dehydrogenase, are provided.Type: GrantFiled: August 8, 2018Date of Patent: November 2, 2021Assignee: ARKRAY, Inc.Inventors: Masaki Murakami, Takehiro Funamoto
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Patent number: 11162120Abstract: Described is a method for the enzymatic production of an acyl phosphate from a 2-hydroxyaldehyde using a phosphoketolase or a sulfoacetaldehyde acetyltransferase.Type: GrantFiled: September 8, 2016Date of Patent: November 2, 2021Assignees: Scientist of Fortune, S.A., Global BioenergiesInventor: Philippe Marlière
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Patent number: 11155838Abstract: It is disclosed a process to produce a fermentation product from a ligno-cellulosic feedstock hydrolyzate slurry which comprises water, water soluble glucose and xylose and water insoluble pretreated ligno-cellulosic feedstock. The process comprises at least two conversion step. A first conversion medium comprising a first portion of the ligno-cellulosic feedstock hydrolyzate slurry and a yeast capable to ferment glucose and xylose is first created, then the yeast is allowed to convert at least 50% of the glucose and less than 20% of the xylose of the first conversion medium to a first propagated yeast and a first portion of the fermentation product in a first conversion step having a first sugar-to-cells conversion ratio in a range of from 5% to 25%.Type: GrantFiled: February 20, 2017Date of Patent: October 26, 2021Assignee: Versalis S.p.AInventor: Fabio Sabbatini
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Patent number: 11155851Abstract: Methods are provided for detecting enzymatic activity of various lysosomal storage enzymes using substrates that include: a sugar moiety; a linker moiety allowing the conjugation of sugar moiety with the remaining structure of the substrate; and two or more fatty acid chains or derivatives thereof at least one of which is sufficiently structured to provide improved solubility in aqueous or organic solvent systems. Also provided are internal standards, and inhibitors for use in detecting or reducing enzymatic activity using the inventive substrates.Type: GrantFiled: June 21, 2016Date of Patent: October 26, 2021Assignees: University of Washington through its Center for Commercialization, PerkinElmer Health Sciences, Inc.Inventors: Alexander Cherkassky, Jason Coumoyer, Michael Gelb
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Patent number: 11136550Abstract: Methods of decontaminating bone tissue and an apparatus or system for the same are provided. The methods can be multi-batch processes and include contacting the bone tissue having contaminants with carbon dioxide to decontaminate the bone tissue and to form carbon dioxide having contaminants. The contaminated carbon dioxide is collected and the contaminants are removed to obtain purified carbon dioxide which can be recycled to treat contaminated bone tissue. The contaminated carbon dioxide can be purified by bubbling it through water and/or an organic solvent followed by acid treatment, filtering and liquefying the carbon dioxide. Contaminants that can be removed from contaminated bone tissue, and in turn, from contaminated carbon dioxide include infectious organisms, bacteria, viruses, protozoa, parasites, fungi and mold or a mixture thereof.Type: GrantFiled: August 13, 2019Date of Patent: October 5, 2021Assignee: Warsaw Orthopedic, Inc.Inventors: Mark DeCaro, Guobao Wei
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Patent number: 11111513Abstract: The present disclosure includes methods and systems for removing one or more fermentation inhibitors (e.g., furfural) from a hydrolysate composition (e.g., a whole broth hydrolysate) by gas stripping the one or more fermentation inhibitors from the hydrolysate composition.Type: GrantFiled: May 18, 2017Date of Patent: September 7, 2021Assignee: POET Research, Inc.Inventors: David Charles Carlson, Benjamin M. Gerdes, Casey C. Jenks, Ryan J. Bouza, Cory James Sarks
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Patent number: 11092600Abstract: A method for detecting at least one microorganism that may be present in a sample, comprising the steps of: a) bringing into contact, in a container: a culture medium that enables the growth and/or detection of microorganisms, said sample and a sensitized solid support; b) subjecting the whole to a temperature that promotes the growth and/or detection of microorganisms; and c) observing, in real time, the appearance of an agglutination indicating the presence of the microorganism(s) or confirming said presence when said microorganisms are detected in said culture medium, when step b) has been completed, and a method for detecting and identifying at least one target microorganism that may be present in a sample.Type: GrantFiled: March 12, 2009Date of Patent: August 17, 2021Assignee: BIOMERIEUXInventors: Bruno Colin, David Mosticone, Jean-Claude Raymond, Thierry Sofia, Antoine Vimont