Patents Examined by Paul D. Pyla
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Patent number: 10624377Abstract: The present invention relates to edible webs comprising microorganisms, such as probiotics. In particular, the present invention relates to an edible web having microorganisms, such as bacteria, probiotic bacteria, bacteriophages or viruses printed thereon, e.g. by the use of inkjet printing. In addition the invention relates to methods of producing such edible webs, to various products comprising the edible webs as well as to use of the edible webs comprising microorganisms.Type: GrantFiled: October 5, 2012Date of Patent: April 21, 2020Assignee: Societe des Produits Nestle S.A.Inventor: Martinas Kuslys
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Patent number: 10602752Abstract: An infant formula for preventing gastro-esophageal reflux is disclosed comprising whey protein and/or casein, a galactomannan thickener, and a fermented milk-derived product.Type: GrantFiled: April 15, 2010Date of Patent: March 31, 2020Assignee: N.V. NUTRICIAInventors: Marie Thomas, Francis Lecroix, Evan Abrahamse, Houkje Bouritius
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Patent number: 10596235Abstract: The pharmaceutical preparation for the treatment of pancreatic insufficiency comprises a liquid administering form of enzymes.Type: GrantFiled: June 15, 2016Date of Patent: March 24, 2020Assignee: Nordmark Arzneimittel GmbH & Co. KGInventors: Christian Rämsch, Manfred Kurfürst, Rainer Friedel, Olaf Friedrich, Silke Hüttler
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Patent number: 10571370Abstract: A method and a machine for drying blood smears and an automatic smearing device are provided. In the method, a dry gas is used as a drying medium to dry a blood film on a blood smear in drying the blood smear, thus reducing drying time and the number of blood smears which are dried together. The dry gas is obtained by: first, removing a liquid from a pressurized gas, second, filtering a vapor, and finally, decompressing the dried pressurized gas to be a non-pressurized gas having lower humidity. In addition, the dry gas is further heated for further reducing the humidity of the dry gas. In order to prevent cell distortion from occurring, the heated dry gas is caused to gently flow over the blood smear in a direction which the blood film is spread.Type: GrantFiled: September 20, 2016Date of Patent: February 25, 2020Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.Inventors: Liang Zhang, Xuerong Li, Yuan Xiang
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Patent number: 10513683Abstract: A structure used for animal cells is provided which includes an elastic body layer having a flat surface on which animal cells are left. The elastic body layer has a surface whose elasticity is changed by partially supporting the elastic body layer from the rear side or by changing a thickness of the elastic body layer.Type: GrantFiled: December 16, 2014Date of Patent: December 24, 2019Assignee: Japan Science and Technology AgencyInventors: Hiroshi Sunami, Ikuko Yokota
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Patent number: 10428306Abstract: Methods of decontaminating bone tissue and an apparatus or system for the same are provided. The methods can be multi-batch processes and include contacting the bone tissue having contaminants with carbon dioxide to decontaminate the bone tissue and to form carbon dioxide having contaminants. The contaminated carbon dioxide is collected and the contaminants are removed to obtain purified carbon dioxide which can be recycled to treat contaminated bone tissue. The contaminated carbon dioxide can be purified by bubbling it through water and/or an organic solvent followed by acid treatment, filtering and liquefying the carbon dioxide. Contaminants that can be removed from contaminated bone tissue, and in turn, from contaminated carbon dioxide include infectious organisms, bacteria, viruses, protozoa, parasites, fungi and mold or a mixture thereof.Type: GrantFiled: August 12, 2016Date of Patent: October 1, 2019Assignee: Warsaw Orthopedic, Inc.Inventors: Mark DeCaro, Guobao Wei
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Patent number: 10280389Abstract: Disclosed are processing systems and processes for carrying out enzymatic batchwise or continuous process for the production of fatty acid alkyl esters for use in the biofuels, food and detergent industries.Type: GrantFiled: December 30, 2013Date of Patent: May 7, 2019Assignee: TRANS BIODIESEL LTD.Inventors: Sobhi Basheer, Usama Mohsen
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Patent number: 10265358Abstract: The present invention relates to a method for the preparation of Medicated Leaven Massa by pure strain fermentation, characterized in that the Medicated Leaven Massa is prepared by fermentation under suitable conditions with Penicillium chrysogenum as a single fermentative strain and the culture medium is made of 6 ingredients, including flour (and/or wheat bran), Artemisia carvifolia, Polygonum flaccidum Meissn., Xanthium sibiricum Patr., Semen Armeniacae Amarum., and Vigna umbellata.Type: GrantFiled: June 17, 2016Date of Patent: April 23, 2019Assignees: Guangdong Pharmaceutical UniversityInventors: Qiuhong Wang, Haixue Kuang, Zunpeng Shu, Changfu Wang
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Patent number: 10213379Abstract: Pharmaceutical formulations in suppository form, containing thrombolytic agents, which are able to penetrate rectal mucous, for the treatment of acute hemorrhoid diseases and/or diseases of thrombotic origin.Type: GrantFiled: December 22, 2003Date of Patent: February 26, 2019Assignee: CENTRO DE INGENIERIA GENETICA Y BIOTECHNOLOGIAInventors: Maria Acelia Marrero Miragaya, Ana Aguilera Barreto, Lisette Gonzalez Chavez, Eduardo Martinez Diaz, Beatriz Torrez Cabrera, Karelia Cosme Diaz, Luciano Francisco Hernandez Marrero, Beatriz Tamargo Santos
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Patent number: 10174351Abstract: The invention relates to a process for the hydrolysis of cellulose containing biomass which comprises a liquefaction step in which a first enzyme or first enzyme composition is added to liquefy at least part of the solids present in the biomass and to keep the viscosity of the cellulose containing biomass below 1000 cP, preferably below 800 cP, more preferably below 600 cP in the liquefaction step; followed by a saccharification step in which a second enzyme composition is added to form oligomeric and/or monomeric sugars; and whereby the first enzyme or first enzyme composition is different from the second enzyme composition; whereby the first enzyme or first enzyme composition comprises an endoglucanase; whereby the second enzyme composition comprises a cellulase; and whereby the first enzyme or first enzyme composition comprises more endogluconase than the second enzyme composition (expressed in protein wt %).Type: GrantFiled: January 9, 2014Date of Patent: January 8, 2019Assignee: DSM IP ASSETS B.V.Inventors: Johannes Petrus Smits, Michael Petrus Jozef Berkhout, Bertus Noordam
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Patent number: 10131923Abstract: The invention relates to a process for the preparation of a fermentation product from ligno-cellulosic material, comprising the following steps: a) optionally pre-treatment of the ligno-cellulosic material; b) optionally washing of the optionally pre-treated ligno-cellulosic material; c) enzymatic hydrolysis of the optionally washed and/or optionally pre-treated ligno-cellulosic material using an enzyme composition comprising at least two cellulase and whereby the enzyme composition at least comprises GH61; d) whereby less than 7.5 mg enzyme composition/g glucan (on dry matter and enzyme as protein) or less than 3.0 mg enzyme composition/g feedstock (on dry matter and enzyme as protein) is used; and e) fermentation of the hydrolyzed ligno-cellulosic material to produce a fermentation product; and f) optionally recovery of a fermentation product; wherein before and/or during the enzymatic hydrolysis oxygen is added to the ligno-cellulosic material.Type: GrantFiled: April 19, 2018Date of Patent: November 20, 2018Assignee: DSM IP ASSETS B.V.Inventors: Bertus Noordam, Michael Petrus Jozef Berkhout
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Patent number: 10130666Abstract: The present invention provides Lactobacillus plantarum CJLP133 KCTC 11403BP, a composition for treating intestinal diseases comprising the lactic acid bacteria, and a composition for enhancing immunity comprising the lactic acid bacteria.Type: GrantFiled: August 21, 2015Date of Patent: November 20, 2018Assignee: CJ CHEILJEDANG CORPInventors: Bong Joon Kim, Heon Woong Jung, Se Hee Hwang, Jin Hee Lee, Kang-Pyo Lee, Kwang Woo Hwang, Tae Joon Won
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Patent number: 10125454Abstract: Described are methods for pretreating lignocellulosic biomass that comprise thermally conditioning the biomass by flow processing an aqueous slurry of the biomass through an outer passage(s) of one or more heat exchange devices while circulating a heat exchange fluid through an inner passage(s) of the heat exchange device(s). Also described are methods for producing fermentation products, especially ethanol, from the pretreated biomass.Type: GrantFiled: June 26, 2009Date of Patent: November 13, 2018Assignees: Purdue Research Foundation, Bowen Engineering CorporationInventors: Michael R. Ladisch, Brian Stater, Bradley Spindler
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Patent number: 10113194Abstract: Apparatuses and associated methods are described for the efficient evaluation of C1-containing substrates, and especially for such evaluation conducted locally, or on-site, at a prospective facility for implementation of a biological conversion process for desired end product using a C1 carbon source. The exact composition of a given, industrial C1-containing substrate, as well as the range in composition fluctuations, are generally difficult to reproduce at a remote facility (e.g., a laboratory or a pilot-scale or demonstration-scale process), as required for the accurate prediction/modeling of commercial performance to justify large capital expenditures for commercial scale-up.Type: GrantFiled: October 21, 2015Date of Patent: October 30, 2018Assignee: LANZATECH NEW ZEALAND LIMITEDInventors: Bjorn Daniel Heijstra, Sean Dennis Simpson, Nicholas Bourdakos, Jason Carl Bromley, Kai-Ming Yap
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Method for preparing yeast beta-D-glucan using solubilization technology based on molecular assembly
Patent number: 10093952Abstract: The present invention provides a method for preparing yeast beta-D-glucan using a solubilization technology based on molecular assembly, comprising the following steps: (1) micro-fluidizing an enzymatic hydrolysate of yeast cell walls at 70 to 200 MPa, and then centrifuging to obtain a precipitate; (2) resuspending the precipitate obtained in step (1) with a ionic liquid, then dispersing to obtain a solution; wherein the ionic liquid is 1-ethyl-3-methylimidazolium acetate or 1-allyl-3-methylimidazolium chloride; (3) centrifuging the solution obtained in step (2), and then adding ethanol, centrifuging and collecting a precipitate; (4) resuspending the precipitate obtained in step (3) with water, then centrifuging and collecting a supernatant. Preferably, the method further comprises (5): spray drying the supernatant obtained in step (4) to obtain a yeast beta-D-glucan powder.Type: GrantFiled: September 4, 2015Date of Patent: October 9, 2018Assignee: Institute of Agro-Products Processing Science and Technology, CAASInventors: Qiang Wang, Hongzhi Liu, Li Liu, Aimin Shi, Hui Hu, Yanan Li, Weijing Lin, Yuquan Duan, Jie Gao, Xiaoyong Liu -
Patent number: 10093995Abstract: Lactobacillus plantarum CJLP243 (KCTC 11045P), a composition for treating intestinal diseases comprising Lactobacillus plantarum CJLP243, and a composition for enhancing immune response comprising Lactobacillus plantarum CJLP243.Type: GrantFiled: October 27, 2010Date of Patent: October 9, 2018Assignee: CJ CHEILJEDANG CORP.Inventors: Bong Joon Kim, Heon Woong Jung, Kang Pyo Lee, Sae Hun Kim, Tae Hoon Chun, Kwang Woo Hwang, Tae Joon Won
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Patent number: 10065877Abstract: The present invention addresses the problem of providing a new microorganism that is useful for efficiently decomposing oils and fats, and a use for said microorganism. According to screening results, a new Yarrowia lipolytica having a high capacity to assimilate free fatty acids was successfully obtained. Efficient decomposition of oils and fats is achieved by causing the Yarrowia lipolytica to act under conditions in which fatty acids that are hydrolysis products of oils or fats are present, or under conditions in which oils or fats are decomposed into fatty acids and glycerol.Type: GrantFiled: January 16, 2013Date of Patent: September 4, 2018Assignee: Nissan Chemical Industries, Ltd.Inventors: Katsutoshi Hori, Masatake Fujioka
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Patent number: 9987337Abstract: Physiologically acceptable anti-biofilm compositions comprising Serratia peptidase and optionally one or more of bromelain, papain and a fibrinolytic enzyme. Additional components can include antimicrobials, antibiotics, antifungals, herbals, chelating agents, lactoferrin and related compounds, minerals, surfactants, binders, and fillers useful for the inhibition and treatment of gastrointestinal biofilms in humans. Physiologically acceptable anti-biofilm compositions containing these enzymes are useful in the inhibition, reduction and/or treatment of biofilms such as in the ear, vagina, joints, bones, gut, surgical sites and other locations, and are useful for the inhibition, reduction and/or treatment of associated systemic symptoms caused by biofilm associated microorganisms.Type: GrantFiled: March 25, 2011Date of Patent: June 5, 2018Assignee: PROTHERA, INC.Inventor: Stephen Francis Olmstead
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Patent number: 9982280Abstract: The invention relates to a process for the preparation of a fermentation product from ligno-cellulosic material, comprising the following steps: a) optionally pre-treatment of the ligno-cellulosic material; b) optionally washing of the optionally pre-treated ligno-cellulosic material; c) enzymatic hydrolysis of the optionally washed and/or optionally pre-treated ligno-cellulosic material using an enzyme composition comprising at least two cellulase and whereby the enzyme composition at least comprises GH61; d) whereby less than 7.5 mg enzyme composition/g glucan (on dry matter and enzyme as protein) or less than 3.0 mg enzyme composition/g feedstock (on dry matter and enzyme as protein) is used; and e) fermentation of the hydrolysed ligno-cellulosic material to produce a fermentation product; and f) optionally recovery of a fermentation product; wherein before and/or during the enzymatic hydrolysis oxygen is added to the ligno-cellulosic material.Type: GrantFiled: November 7, 2013Date of Patent: May 29, 2018Assignee: DSM IP ASSETS B.V.Inventors: Bertus Noordam, Michael Petrus Jozef Berkhout
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Patent number: 9957528Abstract: The invention relates to a process for the preparation of a sugar product from ligno-cellulosic material, comprising the following steps: a) optionally pre-treatment of the ligno-cellulosic material; b) optionally washing of the optionally pre-treated ligno-cellulosic material; c) enzymatic hydrolysis of the optionally washed and/or optionally pre-treated ligno-cellulosic material using an enzyme composition comprising at least two cellulase and whereby the enzyme composition at least comprises GH61; and d) optionally recovery of a sugar product; wherein during part of the time of the enzymatic hydrolysis, oxygen is added to the ligno-cellulosic material and during part of the time of the enzymatic hydrolysis less oxygen is added to the ligno-cellulosic material compared to the other part of the time of the enzymatic hydrolysis, preferably no oxygen is added to the ligno-cellulosic material.Type: GrantFiled: November 7, 2013Date of Patent: May 1, 2018Assignee: DSM IP ASSETS B.V.Inventors: Bertus Noordam, Michael Petrus Jozef Berkhout, Aida Hiseni