Patents Examined by Peter F. Kulkosky
  • Fluidized polymer suspensions of cationic polysaccharides in polyols and use thereof in personal care compositions
    Patent number: 6093769
    Abstract: There are disclosed stable fluidized polymer suspensions containing cationic polysaccharide, stabilizing agent and water-soluble polyol. The preferred cationic polysaccharides are cationic guar and cationic hydroxypropyl guar. Processes for preparing personal care compositions utilizing the fluidized polymer suspensions are also disclosed. Using the fluidized polymer suspensions in the processes provides advantages of more rapid dissolution and avoidance of lumps and gels when compared to using dry, powdered cationic polysaccharides.
    Type: Grant
    Filed: November 19, 1997
    Date of Patent: July 25, 2000
    Assignee: Hercules Incorporated
    Inventors: Charles Lee Burdick, Mohand Melbouci, Hans Hofman, Jacobus Johannes deBruin
  • Process for the production of polyether polyols
    Patent number: 6093793
    Abstract: Polyether polyols are produced by acid-catalyzed polyaddition of alkylene oxides to starter compounds having active hydrogen atoms. Perfluoroalkylsulfonic acid salts of metals from Group IIIA of the Periodic Table of Elements (corresponding to the IUPAC Convention of 1970) are used as the catalyst. The polyaddition reaction is carried out at a temperature of from 40 to 200.degree. C. at normal pressure or pressures from 0 to 20 mbar (absolute). An inert organic solvent may optionally be included in the reaction mixture. Substantially all of the catalyst is removed from the polyether polyol-containing reaction mixture by lowering the temperature and/or by addition of a precipitating agent and/or by extraction with water. If desired, the recovered catalyst may be used in subsequent polyaddition reactions.
    Type: Grant
    Filed: January 20, 1998
    Date of Patent: July 25, 2000
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jorg Hofmann, Pramod Gupta, Harald Pielartzik
  • Kits containing cyanoacrylate compositions comprising an antimicrobial agent
    Patent number: 6090397
    Abstract: Disclosed are kits of parts comprising a first container comprising a cyanoacrylate composition and a second container comprising a compatible antimicrobial agent and, in particular, a compatible iodine containing antimicrobial agent. Mixture of these compositions provide for in situ formation of an antimicrobial polymeric cyanoacrylate film on mammalian skin.
    Type: Grant
    Filed: November 3, 1997
    Date of Patent: July 18, 2000
    Assignee: MedLogic Global Corporation
    Inventors: Connie C. Lee, Richard J. Greff, Ian N. Askill
  • Cyanoacrylate compositions comprising an antimicrobial agent
    Patent number: 6086906
    Abstract: Disclosed are cyanoacrylate compositions comprising a compatible antimicrobial agent and, in particular, a compatible iodine containing antimicrobial agent. These compositions provide for in situ formation of an antimicrobial polymeric cyanoacrylate film on mammalian skin.
    Type: Grant
    Filed: August 18, 1997
    Date of Patent: July 11, 2000
    Assignee: MedLogic Global Corporation
    Inventors: Richard J. Greff, Michael M. Byram
  • Solid glyphosate formulations
    Patent number: 6083875
    Abstract: The present invention relates to a solid herbicidal composition comprising:a) oxyfluorfen herbicide dissolved in at leasti) a surfactant selected from alkoxylated acetylenic diol surfactants;ii) a surfactant selected from polyoxyalkylene alkyl ether surfactants, andiii) an alkoxylated organosilicone based surfactant,iv) a phosphate solvent of low water solubility, the ratio by weight of phosphate solvent to oxyfluorfen being lower than 3 to 1; andb) a water-soluble salt of N-phosphonomethylglycine, and optionallyc) an inorganic carrier,and to a process for the production thereof.
    Type: Grant
    Filed: December 21, 1995
    Date of Patent: July 4, 2000
    Assignee: Monsanto Company
    Inventors: Tatsuo Sato, Masuo Kuchikata, Marc Emile Toussaint
  • Topical compositions for NSAI drug delivery
    Patent number: 6083996
    Abstract: An aqueous pharmaceutical composition of a semi-solid consistency is provided for topical application of non-steroidal anti-inflammatory (NSAI) drugs. The composition comprises one or more NSAI drugs, a non-basic polymeric skin penetration enhancer and a lipophilic solvent. The polymeric skin penetration enhancer is present in an amount sufficient to enhance skin penetration of the NSAI drug. The lipophilic solvent is a mixture of an aliphatic C.sub.2 to C.sub.8 alcohol and an aliphatic C.sub.8 to C.sub.30 ester.
    Type: Grant
    Filed: November 5, 1997
    Date of Patent: July 4, 2000
    Assignee: NexMed Holdings, Inc.
    Inventors: Servet Buyuktimkin, Nadir Buyuktimkin, James Yeager
  • Compositions comprising PVP having an average molecular weight in the range of 3.000 to 14.000 daltons
    Patent number: 6080397
    Abstract: The present invention relates to compositions for use in medicine, e.g. as infusion or surgical rinse solutions, and to processes for their preparation. The compositions of the invention comprise an aqueous solution of physiologically inert PVP having a weight average molecular weight in the range of from 3,000 to 14,000 daltons.
    Type: Grant
    Filed: September 4, 1998
    Date of Patent: June 27, 2000
    Assignee: Ed. Geistlich Sohne AG fur Chemische Industrie
    Inventor: Rolf Wilhelm Pfirrmann
  • Gastric acid binding chewing pastilles
    Patent number: 6077524
    Abstract: The subject matter of the invention is chewing pastilles based on at least partially or complete water soluble natural and/or synthetic polymers, selected from gums, alginates, carrageen, starch, pectin, and gelatin, which will form gels or viscous solutions in aqueous system, and additional adjuvants and additives, said pastilles containing antacids as active ingredients.
    Type: Grant
    Filed: May 16, 1997
    Date of Patent: June 20, 2000
    Assignee: Bolder Arzneimittel GmbH
    Inventors: Hermann-Josef Bolder, Faruk Imer
  • Liposome compositions of porphyrin photosensitizers
    Patent number: 6074666
    Abstract: Liposomal pharmaceutical formulations incorporating porphyrin photosensitizers useful for photodynamic therapy or diagnosis of malignant cells. The liposomal formulations comprise a porphyrin photosensitizer, particularly the hydro-mono benzoporphyrins (BPD) having light absorption maxima in the range of 670-780 nanometers, a disaccharide or polysaccharide and one or more phospholipids.
    Type: Grant
    Filed: June 13, 1995
    Date of Patent: June 13, 2000
    Assignee: QLT Phototherapeutics, Inc.
    Inventors: Narendra Raghunathji Desai, Bushra J. Agha, Kalidas Madhavrao Kale
  • Controlled drug delivery system for diltiazem
    Patent number: 6074669
    Abstract: A pharmaceutical composition in the form of a tablet or a capsule for the controlled release of diltiazem, comprises about 30 to about 97% by weight of a hydrophilic polymer, about 0.5 to about 30% by weight of an enteric (pH-dependent) polymer, and about 2.5 to about 60% by weight of diltiazem or a pharmaceutically acceptable salt or ester thereof. The ratio of hydrophilic polymer to enteric polymer is in the range of about 1:1 to about 15:1. Such a pharmaceutical composition releases diltiazem at a rate that allows effective plasma levels of diltiazem to be maintained over a period of twenty-four hours after administration to human adult subjects.
    Type: Grant
    Filed: December 4, 1997
    Date of Patent: June 13, 2000
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Vishnubhotla Nagaprasad, Himadri Sen
  • Gel freshener and method of making the same
    Patent number: 6071506
    Abstract: A transparent gel air freshener and method of preparing the same. The gel composition comprises an aqueous gel, a fragrance, a surfactant and a co-solvent. The gel is transparent and free from visible particles and inhomogeneities, has a uniform texture and a continuous structure, and includes volatile scented components. The gel is capable of suspending solids such as botanicals therein for decorative effect. The method provides for preparation of a such a gel air freshener, including the suspension of botanicals therein, while maintaining the clarity, texture, and structure of the gel. The method includes the steps of preparing a gel composition and cooling the gel composition. Botanicals may be added to the gel composition when it has gelled enough to support the botanicals on the gel surface.
    Type: Grant
    Filed: June 26, 1997
    Date of Patent: June 6, 2000
    Assignee: Bath & Body Works, Inc.
    Inventors: Steven Semoff, Rueven Sarraf
  • Mimocapsin
    Patent number: 6071507
    Abstract: A composition, and methods for its preparation and use, for the topical treatment of areas of a human body afflicted with arthritis and muscular pain, the composition comprising extracts obtained from branches and leaves collected from mimosa and capsicum plants. The present invention is heated and used in the form of hot compresses and hot baths to treat small afflicted areas and large afflicted areas, respectively. Applications may include, but are not limited to, use in eliminating the pain, swelling, and numbness experienced by people afflicted with arthritis and similar medical conditions.
    Type: Grant
    Filed: July 10, 1996
    Date of Patent: June 6, 2000
    Inventors: Walter Zuluaga, Blanca E. Zuluaga
  • Microparticles containing active ingredients, agents containing these microparticles, their use for ultrasound-controlled release of active ingredients, as well as a process for their production
    Patent number: 6068857
    Abstract: The invention relates to new microparticles containing active ingredients, which contain at least one gas or a gaseous phase in addition to the active ingredient(s), agents containing these particles (microparticulate systems), their use for ultrasound-controlled in vivo release of active ingredients, as well as a process for the production of particles and agents.
    Type: Grant
    Filed: August 5, 1996
    Date of Patent: May 30, 2000
    Assignee: Schering Aktiengesellchaft
    Inventors: Werner Weitschies, Dieter Heldmann, Peter Hauff, Thomas Fritzsch, Harald Stahl
  • Use of redispersible polymer powders or polymer granules as binders for producing solid pharmaceutical presentations
    Patent number: 6066334
    Abstract: Redispersible polymer powders or polymer granules consisting ofa) 10-95% by weight of polyvinyl acetate,b) 5-90% by weight of an N-vinylpyrrolidone-containing polymer,c) 0-20% by weight of another water-soluble or water-swellable substance andd) 0-20% by weight of a water-insoluble dusting agent with or withoute) other additives,are used as binders for producing solid pharmaceutical presentations, where the binder content in the presentation is from 0.5 to 20% by weight.
    Type: Grant
    Filed: March 10, 1998
    Date of Patent: May 23, 2000
    Assignee: BASF Aktiengesellschaft
    Inventors: Karl Kolter, Kristin Tiefensee, Katrin Zeitz
  • Fullerene-containing optical materials with novel light transmission characteristics
    Patent number: 6066272
    Abstract: Optical glasses and polymers are described that incorporate homogeneously dispersed fullerene molecules. The resultant materials may be used as optical filters, the cut-off frequency being easily adjustable by changing the fullerene content. To prepare glasses fullerene molecules are firstly functionalized by amination prior to being incorporated into a sol-gel process to prepare the glass. To prepare polymers a pre-existing polymer may be subject to fullerenation, or fullerene may be copolymerized with a selected monomer.
    Type: Grant
    Filed: October 7, 1996
    Date of Patent: May 23, 2000
    Assignee: The Hong Kong University of Science & Technology
    Inventors: Ben-zhong Tang, Nai-teng Yu, Han Peng, Shuk-mei Leung, Xuan-zheng Wu
  • Cosmetic or dermopharmaceutical patch containing, in an anhydrous polymeric matrix, at least one active compound which is, in particular, unstable in oxidizing mediums, and at least one water-absorbing agent
    Patent number: 6063398
    Abstract: A cosmetic or dermopharmaceutical patch containing, in an anhydrous polymeric matrix, at least one active compound, in particular a compound unstable in oxidizing medium, and at least one water-absorbing agent is disclosed.
    Type: Grant
    Filed: September 8, 1997
    Date of Patent: May 16, 2000
    Assignee: L'Oreal
    Inventor: Jean-Louis H. Gueret
  • Transparent rapid release compositions of non-steroidal analgesics
    Patent number: 6063821
    Abstract: Transparent rapid release active substance compositions obtainable by extrusion of melts, containing non-steroidal analgesics, homopolymers of N-vinylpyrrolidone, saccharides or sugar alcohols and sodium or potassium salts.
    Type: Grant
    Filed: September 16, 1997
    Date of Patent: May 16, 2000
    Assignee: BASF Aktiengesellschaft
    Inventors: Jorg Breitenbach, Axel Sanner, Joerg Rosenberg
  • Macromolecular complexes for drug delivery
    Patent number: 6063370
    Abstract: Novel macromolecular drug complexes containing a drug, like insulin, and a polymer having a plurality of acid moieties, like carboxyl moieties or phosphonic acid moieties, are disclosed. Compositions containing the macromolecular complexes are administered to individuals suffering from a disease, and the complexes release the drug, in vivo, to treat the disease, and to reduce, eliminate, or reverse complications associated with the disease.
    Type: Grant
    Filed: October 2, 1998
    Date of Patent: May 16, 2000
    Assignee: The Board of Trustees of the University of Illinois
    Inventor: Eric J. Dadey
  • Polymer compositions for chemotherapy and methods of treatment using the same
    Patent number: 6060518
    Abstract: Improved antineoplastic compositions comprising an antineoplastic agent combined with a pluronic and a water-soluble non-toxic homopolymer resulting in a decrease of toxicity and/or an increase in anti-cancer activity, and methods of treatment using such formulations.
    Type: Grant
    Filed: August 16, 1996
    Date of Patent: May 9, 2000
    Assignee: Supratek Pharma Inc.
    Inventors: Alexander V. Kabanov, Valery Yu. Alakhov
  • Copolymer-1 improvements in compositions of copolymers
    Patent number: 6054430
    Abstract: The present invention relates to an improved composition of copolymer-1 comprising copolymer-1 substantially free of species having a molecular weight of over 40 kilodaltons.
    Type: Grant
    Filed: February 27, 1998
    Date of Patent: April 25, 2000
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: Eliezer Konfino, Michael Sela, Dvora Teitelbaum, Ruth Arnon