Patents Examined by Phillip Johnston
  • Patent number: 10684256
    Abstract: In order to make an analyzer with an ion mobility separation part have high durability and robustness, the analyzer includes an ion source, an ion mobility separation part which includes a pair of facing electrodes to which a high frequency voltage and a DC voltage are applied, and a shielding electrode which is provided between the ion source and the ion mobility separation part and to which a DC voltage is applied, wherein the shielding electrode includes an ion flow path connecting an inlet from which ions from the ion source are introduced and an outlet from which the ions are discharged thereinside, and the ion flow path is bent so that the outlet is unable to be seen from the inlet.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: June 16, 2020
    Assignee: Hitachi High-Tech Corporation
    Inventors: Hiroyuki Satake, Kazushige Nishimura, Hideki Hasegawa, Masuyuki Sugiyama
  • Patent number: 10684380
    Abstract: Generally, a method or apparatus for tomographically imaging a sample, such as a tumor of a patient, using positively charged particles positions n two-dimensional detector arrays on n surfaces of a scintillation material or scintillator, respectively. Resultant from energy transfer from the positively charged particles, secondary photons are emitted from the scintillation material and detected by the plurality of two-dimensional detector arrays, where each detector array images the scintillation material. Combining signals from the plurality of two-dimensional detector arrays, the path, position, energy, and/or state of the positively charged particle beam as a function of time and/or rotation of the patient relative to the positively charged particle beam is determined and used in tomographic reconstruction of an image of the sample or the tumor.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: June 16, 2020
    Inventors: W. Davis Lee, Mark R. Amato
  • Patent number: 10687410
    Abstract: An extreme ultraviolet radiation source is provided, including a vessel, an optical collector, and a gas scrubber. The vessel has a gas inlet and a gas outlet. The optical collector is disposed within the vessel and configured to collect and reflect extreme ultraviolet light produced in the vessel. A cleaning gas is introduced into the vessel through the gas inlet to clean the surface of the optical collector. The gas scrubber is disposed within the vessel, arranged such that the cleaning gas leaves the vessel through the gas outlet after flowing through the gas scrubber. The gas scrubber has a number of gas passages to allow the cleaning gas to flow through, and the size of the gas passage close to the gas outlet is smaller than the size of the gas passage away from the gas outlet.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: June 16, 2020
    Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD.
    Inventors: Chi Yang, Sheng-Ta Lin, Shang-Chieh Chien, Li-Jui Chen, Po-Chung Cheng
  • Patent number: 10678138
    Abstract: The EUV radiation source includes a rotatable EUV source vessel configured to collect fuel debris generated from the collision of fuel droplets and a laser beam. The source vessel includes an inner surface for receiving the fuel debris, an first aperture at one end of the inner surface, and a heater adjacent to the inner surface and configured to generate a heating area on the inner surface in coordination with a rotation speed of the source vessel. The fuel debris is reflowed to the heating area. A method for generating EUV radiation includes collecting fuel debris on an inner surface of a source vessel, rotating the source vessel at a rotation speed, and heating a portion of the source vessel to an elevated temperature to generate a heating area on the inner surface in coordination with the rotation speed. The fuel debris is reflowed to the heating area.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: June 9, 2020
    Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY LTD.
    Inventors: Wei-Chun Yen, Chi Yang, Shang-Chieh Chien, Li-Jui Chen, Po-Chung Cheng
  • Patent number: 10675486
    Abstract: Systems, devices, and methods for quality assurance for verification of radiation dose delivery in arc-based radiation therapy devices using a 3D gamma evaluation method.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: June 9, 2020
    Assignee: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG
    Inventors: Lasse Heikki Toimela, Janne Nord
  • Patent number: 10665442
    Abstract: A mass spectrometer is provided that includes a precursor ion candidate selector, a product ion scan measurement condition setter, a product ion spectral data obtainer, a compound database file generator, and an MRM measurement condition candidate generator. The precursor ion candidate selector selects precursor ion candidates from mass spectrometric data. The product ion scan measurement condition setter combines the precursor ion candidates with a plurality of candidate values of cleavage energy to set a product ion scan measurement condition. The product ion spectral data obtainer carries out MS/MS measurement to obtain product ion spectral data. The compound database file generator generates a compound database file in which the product ion scan measurement condition and the product ion spectral data are associated with each other.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: May 26, 2020
    Assignee: SHIMADZU CORPORATION
    Inventor: Takeshi Ashida
  • Patent number: 10663380
    Abstract: A multiple degree of freedom sample stage or testing assembly including a multiple degree of freedom sample stage. The multiple degree of freedom sample stage includes a plurality of stages including linear, and one or more of rotation or tilt stages configured to position a sample in a plurality of orientations for access or observation by multiple instruments in a clustered volume that confines movement of the multiple degree of freedom sample stage. The multiple degree of freedom sample stage includes one or more clamping assemblies to statically hold the sample in place throughout observation and with the application of force to the sample, for instance by a mechanical testing instrument. Further, the multiple degree of freedom sample stage includes one or more cross roller bearing assemblies that substantially eliminate mechanical tolerance between elements of one or more stages in directions orthogonal to a moving axis of the respective stages.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: May 26, 2020
    Assignee: Bruker Nano, Inc.
    Inventors: Edward Cyrankowski, Syed Amanulla Syed Asif, Ryan Major, Derek Rasugu, Yuxin Feng
  • Patent number: 10656059
    Abstract: A method for qualitative and quantitative multiplexing of drug analytes from dried blood samples includes the steps of mixing an Internal Standard solution with a first diluent in a vessel, adding the dried blood sample to the vessel, sonicating the vessel containing the Internal Standard solution, the first diluent and the dried blood sample, removing the dried blood sample from the vessel so that a final sample can be attained, and analyzing at least a portion of the final sample using one of LC-MS and LC-MS/MS to simultaneously determine the presence or absence of a plurality of different analytes in the dried blood sample. The Internal Standard solution can include at least 8, 15, 25 or 50 Internal Standards. The dried blood sample is generated using less than 50 ?L, 20 ?L or 10 ?L of blood. The step of analyzing includes simultaneously determining the presence or absence of at least 15, 60, 90 or 130 different analytes.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: May 19, 2020
    Assignee: ALCALA PHARMACEUTICAL, INC.
    Inventors: David J. Smith, Matthew D. Rifat, Christian Tagwerker, Irfan Baig, Ranulu Samanthi de Zoysa, Eric J. Brunson
  • Patent number: 10658151
    Abstract: To provide a lightweight and highly rigid stage device that can move in X and Y directions and a Z direction, and a charged particle beam device including the stage device. A stage device includes a chuck that is loaded with a sample, an XY stage that moves in X and Y directions, and a Z stage that moves in a Z direction. The Z stage includes: an inclined part that is fixed to the XY stage and includes an inclined surface inclined with respect to an XY plane; a movement part that moves on the inclined surface; and a table that is fixed to the movement part and is provided with the a plane parallel to the XY plane.
    Type: Grant
    Filed: January 7, 2019
    Date of Patent: May 19, 2020
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Motohiro Takahashi, Masaki Mizuochi, Shuichi Nakagawa, Tomotaka Shibazaki, Naruo Watanabe, Akira Nishioka, Takanori Kato, Hironori Ogawa
  • Patent number: 10641461
    Abstract: A light illuminating apparatus for irradiating light of a line shape extending in a first direction and having a predetermined line width in a second direction perpendicular to the first direction, includes a light emitting unit including a substrate, and a plurality of light sources arranged at a predetermined interval along the first direction on the substrate such that an optical axis is matched to a third direction perpendicular to the first and second directions, and a mirror unit having a mirror surface to reflect and focus the light. In a cross section of the mirror unit taken along a plane defined by the second direction and the third direction, a cross-sectional shape of the mirror surface is a curved shape resulting from rotation of each of a horizontal axis direction positive side part and a horizontal axis direction negative side part of a parabola y=ax2.
    Type: Grant
    Filed: July 3, 2018
    Date of Patent: May 5, 2020
    Assignee: HOYA CANDEO OPTRONICS CORPORATION
    Inventor: Kazutaka Shito
  • Patent number: 10643834
    Abstract: In various embodiments of the invention, a cargo container can be monitored at appropriate time intervals to determine that no controlled substances have been shipped with the cargo in the container. The monitoring utilizes reactive species produced from an atmospheric analyzer to ionize analyte molecules present in the container which are then analyzed by an appropriate spectroscopy system. In an embodiment of the invention, a sorbent surface can be used to absorb, adsorb or condense analyte molecules within the container whereafter the sorbent surface can be interrogated with the reactive species to generate analyte species characteristic of the contents of the container.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: May 5, 2020
    Assignee: IONSENSE, INC.
    Inventor: Brian D Musselman
  • Patent number: 10636640
    Abstract: In various embodiments of the invention, a sorbent coated mesh or grid introduced into contact with a sample can be monitored at appropriate temperatures, positions and time intervals to determine species present in the sample. The monitoring utilizes reactive species produced from an atmospheric analyzer to ionize analyte molecules present on the sorbent coated mesh or grid which are then analyzed by an appropriate spectroscopy system. In an embodiment of the invention, a sorbent surface can be used to absorb, adsorb or condense analyte molecules from the sample whereafter the sorbent surface can be interrogated with the reactive species to generate analyte species characteristic of the sample.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: April 28, 2020
    Assignee: IONSENSE, INC.
    Inventor: Brian D Musselman
  • Patent number: 10633402
    Abstract: A novel method and system for using certain tin compounds as dopant sources for ion implantation are provided. A suitable tin-containing dopant source material is selected based on certain attributes. Some of these attributes include stability at room temperature; sufficient vapor pressure to be delivered from its source supply to an ion chamber and, the ability to produce a suitable beam current for ion implantation to achieve the required implant Sn dosage.
    Type: Grant
    Filed: January 16, 2019
    Date of Patent: April 28, 2020
    Assignee: Praxair Technology, Inc.
    Inventors: Aaron Reinicker, Ashwini K. Sinha, Qiong Guo
  • Patent number: 10629420
    Abstract: An ion intensity array is computed for each mass spectrum forming a mass spectrum array. For each ion intensity array, a plurality of indices a˜e showing a plurality of characteristics of the mass spectrum as a whole are computed. Based on the plurality of indices, a plurality of index distribution images are computed. A plurality of index distribution images may alternatively be computed based on a mass image array generated from the mass spectrum array.
    Type: Grant
    Filed: January 23, 2019
    Date of Patent: April 21, 2020
    Assignee: JEOL Ltd.
    Inventor: Takaya Satoh
  • Patent number: 10627471
    Abstract: Systems and methods for monitoring and improving the treatment of biomass are described.
    Type: Grant
    Filed: May 1, 2019
    Date of Patent: April 21, 2020
    Assignee: XYLECO, INC.
    Inventors: Marshall Medoff, Thomas Craig Masterman, Dennis Michaud, Gerard Palace
  • Patent number: 10627287
    Abstract: A Thomson scattering measurement system according to the present disclosure includes: a transfer optical system provided on an optical path of a slit light beam group generated by division through a slit array and configured to transfer the slit light beam group to a plurality of transfer image groups separated from each other; and a second slit provided on an optical path of light from the transfer image groups and configured to selectively allow light from a plurality of transfer images positioned on a straight line extending in a direction corresponding to a first direction to pass through the second slit, the transfer images corresponding to slit light beams at positions different from each other in a second direction in the slit light beam group among transfer images included in the transfer image groups.
    Type: Grant
    Filed: June 10, 2019
    Date of Patent: April 21, 2020
    Assignee: Gigaphoton Inc.
    Inventors: Kouichiro Kouge, Tatsuya Yanagida
  • Patent number: 10631444
    Abstract: A supply module for supplying a weapon system includes an electric storage device and a thermal storage device that stores coolant. The supply module also includes at least one electrical connection via which power can be transferred from the electric storage device to the effector system, and at least one thermal connection via which the coolant can be transferred from the thermal storage device to the effector system.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: April 21, 2020
    Assignee: MBDA Deutschland GmbH
    Inventor: Rudolf Protz
  • Patent number: 10627354
    Abstract: This substitution site measuring equipment using an electron beam analyzes, with high precision, the structure of a substitution site in a micrometer- to nanometer-order region, by reducing or vanishing the X-ray intensity of diffraction X-rays generated in a specimen. The substitution site measuring equipment measures a substitution site in a crystal by detecting, by means of an X-ray detector, X-rays generated from a specimen upon irradiation of the specimen with an electron beam.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: April 21, 2020
    Assignee: Hitachi, Ltd.
    Inventors: Yoshihiro Anan, Masanari Koguchi
  • Patent number: 10622203
    Abstract: A mass analyzing apparatus and system are disclosed for time-of-flight (“TOF”) mass spectrometry analysis. A representative system includes a first electrostatic mirror prism to reflect a first ion beam and provide an intermediate ion beam having an intermediate TOF focus and having a spatial dispersion of ions proportional to ion kinetic energies; and a second electrostatic mirror prism to reflect the second ion beam and converge the spatial dispersion of ions to provide a third, recombined ion beam having an output TOF focus; and an ion detector arranged at the output TOF focus to receive and detect the ions of the third ion beam. A bandpass filter may be arranged at the intermediate TOF focus to selectively allow propagation of ions of the second ion beam having a selected range of ion kinetic energies. Configurations having additional electrostatic mirror prisms are disclosed, including for tandem MS-MS and selectable time-of-flight.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: April 14, 2020
    Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Igor Vladimirovich Veryovkin, Luke Hanley
  • Patent number: 10624249
    Abstract: A method of producing a garment having at least one electromagnetic radiation shielded zone and a corresponding garment are disclosed.
    Type: Grant
    Filed: January 1, 2017
    Date of Patent: April 14, 2020
    Inventor: Andrea Zemberyová