Patents Examined by Qing Xu
  • Patent number: 11457635
    Abstract: The present invention relates to Podoviridae bacteriophage Pse-AEP-3 (accession number: KCTC 13165BP) isolated from nature, the Podoviridae bacteriophage Pse-AEP-3 having the capability to specifically kill Pseudomonas aeruginosa and having a genome represented by SEQ ID NO: 1, and a method for preventing or treating diseases induced by Pseudomonas aeruginosa by using a composition containing the Podoviridae bacteriophage Pse-AEP-3 as an active ingredient.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: October 4, 2022
    Inventors: Seong Jun Yoon, Soo Youn Jun, Jee Soo Son, Hyoun Rok Paik, Hee Jeong Shin, Sang Hyeon Kang
  • Patent number: 11459554
    Abstract: The present invention relates to an enzyme complex which the following (i) to (iv) are combined: (i) chimeric beta-agarase formed by a fusion of beta-agarase and the dockerin module of endo-?-1,4-glucanase-B; (ii) chimeric kappa-carrageenase formed by a fusion of kappa-carrageenase and the dockerin module of endo-?-1,4-glucanase-B; (iii) chimeric anhydro-galactosidase formed by a fusion of anhydro-galactosidase and the dockerin module of endo?-1,4-glucanase-B; and (iv) mini cellulose-binding protein A, and to a method of degrading red algal biomass using the same. According to the present invention, an enzymatic degradation process is applied for the production of agar degradation products, deviating from conventional methods that relied on physical and chemical pretreatment processes.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: October 4, 2022
    Assignee: Korea University Research and Business Foundation
    Inventors: Sung Ok Han, Dae-Hee Kang, Jeong-Eun Hyeon
  • Patent number: 11458177
    Abstract: The present invention relates to Siphoviridae bacteriophage Ent-FAP-4 (accession number KCTC 12854BP), separated from nature, which is capable of specifically killing Enterococcus faecium and has a genome expressed by sequence number 1, a pharmaceutical composition, which comprises same as an active ingredient, and a method for preventing or treating diseases, induced by Enterococcus faecium, by administering the pharmaceutical composition.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: October 4, 2022
    Inventors: Seong Jun Yoon, Soo Youn Jun, Hyoun Rok Paik, Jee Soo Son, Sang Hyeon Kang
  • Patent number: 11452745
    Abstract: The present invention generally relates to the field of probiotic bacteria. In particular, it relates to methods for treating or preventing functional GI disorders comprising administering Bifidobacterium longum, such as Bifidobacterium longum ATCC BAA-999.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: September 27, 2022
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Peter McLean, Gabriela Bergonzelli Degonda, Stephen Michael Collins, Premysl Bercik, Elena Verdu de Bercik
  • Patent number: 11421256
    Abstract: The invention relates to a process for the preparation of a fermentation product from ligno-cellulosic material, comprising the following steps: a) optionally pre-treatment b) optionally washing; c) enzymatic hydrolysis; d) fermentation; and e) optionally recovery of a fermentation product; wherein in step c) an enzyme composition is used that has a temperature optimum of 55 degrees C. or more, the hydrolysis time is 40 hours or more and the temperature is 50 degrees C. or more.
    Type: Grant
    Filed: October 17, 2018
    Date of Patent: August 23, 2022
    Assignee: DSM IP ASSETS B.V.
    Inventors: Johannes Petrus Smits, Elisabeth Maria Gierveld, Fop Van Der Hor
  • Patent number: 11415513
    Abstract: A method for determining the degree of sensitivity of a strain of fungus to an antifungal agent by using the possible change in a chitin level in a population of cells of a strain of fungus to an antifungal agent. The change is determined compared to the chitin level of a population of cells of said strain of fungus in the absence of antifungal agent.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: August 16, 2022
    Inventors: Delphine Paule Renee Morin-Aldebert, Murielle Monique Jacqueline Cornet-Gigou
  • Patent number: 11412760
    Abstract: The present invention relates to a Myoviridae bacteriophage ESC-COP-7 (accession number KCTC 13130BP) isolated from nature, and a method for preventing and treating infections from pathogenic Escherichia coli by means of a composition containing the Myoviridae bacteriophage ESC-COP-7 as an active ingredient, the Myoviridae bacteriophage ESC-COP-7 being characterized by having the capability to specifically kill Escherichia coli, and genome expressed by the SEQ ID 1.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: August 16, 2022
    Inventors: Seong Jun Yoon, Soo Youn Jun, Hyoun Rok Paik, Jee Soo Son, SAng Hyeon Kang
  • Patent number: 11391732
    Abstract: A process for capturing or concentrating microorganisms for detection or assay comprises (a) providing a concentration agent that comprises an amorphous metal silicate and that has a surface composition having a metal atom to silicon atom ratio of less than or equal to about 0.5, as determined by X-ray photoelectron spectroscopy (XPS); (b) providing a sample comprising at least one microorganism strain; and (c) contacting the concentration agent with the sample such that at least a portion of the at least one microorganism strain is bound to or captured by the concentration agent.
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: July 19, 2022
    Assignee: 3MInnovative Properties Company
    Inventors: Manjiri T. Kshirsagar, Tushar A. Kshirsagar, Thomas E. Wood
  • Patent number: 11352596
    Abstract: The invention relates to a method for producing biogas from lignocellulose-containing biomass, preferably from straw, and to a plant for carrying out said method.
    Type: Grant
    Filed: December 16, 2013
    Date of Patent: June 7, 2022
    Inventors: Oliver Ludtke, Michael Schlimbach, Enrico Fichter, Jens Horn, Georg Pollert, Jan Kuhling
  • Patent number: 11293926
    Abstract: Provided is a method for preparing a sugar chain, including: a labeling step of adding a labeling reagent to a sugar chain-containing sample which contains a sugar chain to obtain a labeled product containing a labeled substance of the sugar chain, in which a reaction environment of the labeling reagent and the sugar chain contains water in the labeling step.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: April 5, 2022
    Inventor: Masaaki Toyoda
  • Patent number: 11291711
    Abstract: Subjects of the invention are a method of plasminogen supplementation in a plasminogen-deficient subject, and method for the treatment of plasminogen-deficiency in a plasminogen-deficient subject. These methods comprise administering to the plasminogen-deficient subject a dose of plasminogen, and more particularly Glu-plasminogen, for increasing the subject plasminogen activity level by at least about 1%, and more particularly by at least 10%, of the normal plasminogen activity and for maintaining the plasminogen activity level over a supplementation period or a treatment period. The plasminogen-deficient subject of the present invention may suffer from Type-I, Type-II plasminogen-deficiency or an acquired deficiency.
    Type: Grant
    Filed: November 3, 2016
    Date of Patent: April 5, 2022
    Inventors: Martin Robitaille, Karen Thibaudeau, Pierre Laurin, Stacy Plum
  • Patent number: 11274321
    Abstract: Compositions and methods for a hybrid biological and chemical process that captures and converts carbon dioxide and/or other forms of inorganic carbon and/or CI carbon sources including but not limited to carbon monoxide, methane, methanol, formate, or formic acid, and/or mixtures containing CI chemicals including but not limited to various syngas compositions, into organic chemicals including biofuels or other valuable biomass, chemical, industrial, or pharmaceutical products are provided. The present invention, in certain embodiments, fixes inorganic carbon or CI carbon sources into longer carbon chain organic chemicals by utilizing microorganisms capable of performing the oxyhydrogen reaction and the autotrophic fixation of CO2 in one or more steps of the process.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: March 15, 2022
    Assignee: Kiverdi, Inc.
    Inventors: John S. Reed, Lisa Dyson
  • Patent number: 11248249
    Abstract: The present invention provides a method for determining whether or not a sample contains at least one of Cercospora fungus and Pseudocercospora fungus. In the method, first, the sample is added an aqueous solution containing N,N,N?,N?-Tetramethyl-1,4-phenylenediamine and 5-(2,4-disulfophenyl)-3-(2-methoxy-4-nitrophenyl)-2-(4-nitrophenyl)-2H-tetrazolium to provide a mixture. The aqueous solution has a pH of not less than 5.1 and not more than 6.5. Then, the mixture is irradiated with light having a wavelength of 400 to 500 nanometers to measure a first absorbance Ay of the mixture, and the mixture is irradiated with light having a wavelength of 500 to 800 nanometers to measure a second absorbance Ax of the mixture. If the value of Ay/Ax is not less than 1.5 or the mixture is orangey, it is determined that the sample contains at least one of Cercospora fungus and Pseudocercospora fungus.
    Type: Grant
    Filed: September 5, 2019
    Date of Patent: February 15, 2022
    Inventors: Yuki Kushida, Yosifumi Kariatumari
  • Patent number: 11247964
    Abstract: The present invention provides methods of processing lipid materials such as soapstock, wet gums and dry gums. Enzymes are utilized to catalyze hydrolysis of the lipids materials to recover fatty acids. Addition of organic acids and/or polyols improved yield of fatty acids and reduced formation of emulsion. Lipid materials can be formulated with other agricultural products as new value-added animal feed products. Further, a process for concentrating nitrogenous compounds such as choline, inositol, ethanolamine and serine from phospholipid materials obtained as byproducts from vegetable oil refining is provided. The process involves performing hydrolysis of the gum based products in the presence of an alcoholic solvent and acid catalyst. Post hydrolysis, gums breakdown to oil and water phases which are further separated and concentrated. These concentrated products may be further fractionated to concentrate individual nitrogenous compounds.
    Type: Grant
    Filed: April 18, 2016
    Date of Patent: February 15, 2022
    Assignee: RRIP, LLC
    Inventors: Mohan Prasad A. Dasari, Abdullah A. Mahfuz, Shashank Ravi, Hugh Tallant Warren
  • Patent number: 11230691
    Abstract: A method and apparatus for enzymatic hydrolysis where a plant based feed is hydrolysed using an enzyme to form a hydrolysed product. An additive for preventing enzyme adsorption is fed to an enzymatic hydrolysis stage, the plant based feed, the hydrolysed product, a starting material, and/or a plant based material formed from the starting material. The hydrolysed product is supplied from the enzymatic hydrolysis stage to a first solid-liquid separation stage where a lignin fraction comprising the additive and a liquid composition comprising the enzyme are separated. The liquid composition is mixed with the plant based material in a mixing stage, forming a mixture. A solid and liquid fraction are separated from the mixture in a second solid-liquid separation stage. At least part of the solid fraction comprising the enzyme is fed as the plant based feed to the enzymatic hydrolysis stage.
    Type: Grant
    Filed: October 12, 2017
    Date of Patent: January 25, 2022
    Inventors: Sami Turunen, Mauno Miettinen, Meri Ventola, Juha Tamper
  • Patent number: 11219218
    Abstract: Method of inhibiting live grazing organisms in an algae composition are disclosed, which do not inhibit the algae. In certain embodiments the concentration of algae increases. In other embodiments the mortality of live grazing organisms is complete. The method contacts an algae composition with wastewater comprising free ammonia and maintaining pH of at least 8 for more than two hours.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: January 11, 2022
    Assignee: Boise State University
    Inventors: Patrick Thomas, Kevin Feris, Maxine Passero, Gary Dunn
  • Patent number: 11198848
    Abstract: The present invention relates to a certain microorganism for altering the composition of oral biofilms, in particular for use in the treatment and/or prevention of dental caries and/or periodontal disease. In particular, the present invention relates to a microorganism for use as a probiotic agent for altering the bacterial composition of oral biofilms derived from saliva, preferably for reducing the proportions of Gram-negative anaerobic genera and/or increasing the proportions of aerobic or facultatively anaerobic genera. Furthermore, the present invention provides oral pharmaceutical compositions, oral care products or products for nutrition or pleasure comprising the microorganism as probiotic agents as well as a method of production thereof.
    Type: Grant
    Filed: January 18, 2017
    Date of Patent: December 14, 2021
    Assignees: SYMRISE AG, PROBI AB
    Inventors: William Wade, Marcus Rudolf Götz, Manuel Pesaro
  • Patent number: 11181534
    Abstract: Compositions and methods useful for point of care testing for hemophilia by measuring coagulation factor levels are provided.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: November 23, 2021
    Assignee: Bloodworks
    Inventors: Jill Marie Johnsen, Barbara A. Konkle
  • Patent number: 11174460
    Abstract: Efficient stem cell delivery into biomaterials using capillary driven encapsulation are disclosed herein where stem/progenitor and/or tissue specific cells are rapidly and efficiently seeded via capillary driven encapsulation into a porous scaffold for cell delivery in the skin or any other organ. The rapid capillary force approach maximizes both seeding time and efficiency by combining hydrophobic, entropic and capillary forces to promote active, ‘bottom-up’ cell engraftment. This methodology uses micro domain patterned biopolymers in a porous dry gel to generate capillary pressure to move a viscous stem cell mix from a hydrophobic reservoir into the polymer matrix to promote active cell seeding within the entire gel volume.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: November 16, 2021
    Inventors: Geoffrey C. Gurtner, Jayakumar Rajadas, Robert C. Rennert
  • Patent number: 11168341
    Abstract: The invention relates to a method for producing aminobenzoic acid or a aminobenzoic acid derivative via the fermentation of a suitable raw material under the influence of suitable microorganisms and obtaining a fermentation broth containing aminobenzoate and/or aminobenzoic acid. In particular, the invention relates to the step of obtaining the aminobenzoic acid from the fermentation broth, wherein the crystallisation of aminobenzoic acid is carried out via a simple one-stage acid treatment in the presence of seed crystals. The aminobenzoic acid crystallised in this simple manner can be easily separated from the mother liquor, further cleaned if necessary, and then supplied to the different applications.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: November 9, 2021
    Assignee: Covestro Deutschland AG
    Inventors: Gernot Jäger, Wolfgang Beckmann, Amgad Salah Moussa, Guenter Olf, Guido Becker, Hasan Akyildiz, Andreas Damm, Thomas Hamedinger, Wolf Kloeckner, Swantje Behnken