Patents Examined by Qing Xu
  • Patent number: 11806462
    Abstract: A triple syringe system that allows for a larger combined output of PRP (platelet rich plasma) and PPP (platelet poor plasma). The multi-syringe system allows for the connection of two or more additional syringes. The fractions may be extracted with the multi-syringe system of the present invention at different sequential times, or at the same time.
    Type: Grant
    Filed: April 6, 2021
    Date of Patent: November 7, 2023
    Assignee: Arthrex, Inc.
    Inventor: Christopher Bare
  • Patent number: 11759505
    Abstract: The present invention relates to a method for isolating Glu-plasminogen, said method comprising the anion exchange chromatography of blood plasma or a plasma fraction comprising Glu-plasminogen. Furthermore, the present invention relates to Glu-plasminogen obtainable from the method of the present invention and its use in a method for treating a patient suffering from or being at risk of developing a disorder selected from the group consisting of organ failure, a thrombotic event, arterial obstructive disease, microcirculation, disseminated intravascular coagulation (DIC), and a combination of two or more thereof.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: September 19, 2023
    Assignee: PREVIPHARMA CONSULTING GMBH
    Inventors: Ricarda Welz, Hanne Rieke Gerding, Marc Mazur, Stephan T. Kiessig, Hermann E. Karges
  • Patent number: 11718892
    Abstract: The invention provides an assay for identifying a bacterium capable of binding elemental heavy metal, comprising the following steps: cultivating a test bacterium in a suitable first culture medium; immersing at least a surface portion of a test tool into the first culture medium for a second predetermined period of time, said surface portion being coated by elemental heavy metal, respectively; removing said test tool from said first culture medium and optionally rinsing the test tool; contacting a second culture medium with the surface portion coated by elemental heavy metal of said test tool removed in the previous step; and identifying the test bacterium as being capable of binding elemental heavy metal from growth of the test bacterium in said second culture medium.
    Type: Grant
    Filed: October 18, 2019
    Date of Patent: August 8, 2023
    Assignee: CvPlus GmbH
    Inventors: Stephen Gos, Andrea Christiansen, Xin Lu, Guido Meurer, Yvonne Tiffert, Esther Gabor, Benedikt Hoffmann, Martin Langer
  • Patent number: 11680250
    Abstract: The present disclosure relates to a light-driven system which is able to chemically modify an organic substrate with high efficiency and in a cost-effective manner. Also provided are methods for chemically modifying an organic substrate using the present systems and methods for manufacturing such systems.
    Type: Grant
    Filed: July 14, 2016
    Date of Patent: June 20, 2023
    Assignee: University of Copenhagen
    Inventors: Claus Felby, David Cannella, Klaus Benedikt Möllers
  • Patent number: 11659839
    Abstract: Provided is a component having plant defense activity. A PR1 gene expression activator containing a culture of a unicellular alga containing a green photosynthetic pigment as an active ingredient; A plant defense activator containing a culture of a unicellular alga containing a green photosynthetic pigment as an active ingredient; A plant disease preventive or ameliorating agent containing a culture of a unicellular alga containing a green photosynthetic pigment as an active ingredient; and a method of producing a plant defense activating component containing: cultivating a unicellular alga containing a green photosynthetic pigment under an aerobic condition to produce a culture containing an extracellular polysaccharide.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: May 30, 2023
    Assignees: PANAC CO., LTD., NATIONAL INSTITUTE OF TECHNOLOGY AND EVALUATION
    Inventors: Gouki Satou, Toshichika Ooki, Masahiro Koide, Hiroshi Sekiguchi
  • Patent number: 11583566
    Abstract: The invention discloses the use of the Schizochytrium limacinum and its preparation in improving the quality and yield of animal product. The deposit number of Schizochytrium limacinum in the present invention is CGMCC No. 13746 in the China General Microbiological Culture Collection Center. The Schizochytrium limacinum powder produced by the Schizochytrium limacinum may increase the DHA content in an animal product, reduce the cholesterol content in an animal product, and also improve the egg production performance of poultry. This animal product with high DHA content from natural sources is organic, safe, stable, and easy to be absorbed. It may be used as a safer and effective way for people to ingest natural DHA, and it may also cater to and meet consumer needs. Thus, Schizochytrium limacinum and Schizochytrium limacinum powder of the present application have a wide range of application in the field of general food and livestock breeding.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: February 21, 2023
    Assignee: XIAMEN HUISON BIOTECH CO., LTD
    Inventors: Liyi Chen, Huichang Zhong, Shuirong Chen
  • Patent number: 11560580
    Abstract: A process for producing a solid material comprising isomaltulose crystals and trehalulose, including: A) contacting an enzyme complex with a sucrose-containing solution; B) isomerizing at least a part of the sucrose to isomaltulose and trehalulose; C) separating off the enzyme complex to obatin a solution including isomaltulose, trehalulose and water; D) partially removing the water by evaporation to obtain a concentrated solution; E) bringing the concentrated solution to a temperature range of 30° C. to 63° C. and subsequently inducing isomaltulose crystallization in this temperature range followed by cooling, thereby obtaining a solid material including isomaltulose crystals and trehalulose.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: January 24, 2023
    Assignee: Evonik Operations GmbH
    Inventors: Frank Hellmers, Sibylle Schlegel-Kachel, Johannes Oehrlein, Jan Wolter
  • Patent number: 11549081
    Abstract: Provided are methods to destabilize emulsion feedstocks. In the methods, a moderate temperature is applied to the feedstock to create a first mixture. The moderate temperature may be between 120 and 220 degrees Celsius. The first mixture is mixed at the moderate temperature, such as by staged mixing in some embodiments. Moreover, the first mixture is retained at the moderate temperature for up to six hours. The first mixture is separated into an oil phase, convoluted phase, and a water phase. In some embodiments, the moderate temperature may be 125 to 150 degrees Celsius, such as between 125 and 130 degrees Celsius. Moreover, the first mixture may be retained at the moderate temperature for between forty-five minutes and four hours, such as from two to four hours. The separation may occur at the moderate temperature.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: January 10, 2023
    Assignee: RRIP, LLC
    Inventors: Mohan Prasad A. Dasari, Hugh Tallant Warren
  • Patent number: 11513109
    Abstract: A biological toxicity test method for evaluating an ecological safety of an advanced oxidation process comprising the following steps: (1) collecting (preparing) a waste water to be determined; (2) collecting the waste water and a tap water after the advanced oxidation process treatment; (3) subjecting Koi (Cyprinus carpio haematopterus) to the water after treatment for exposure to poison; (4) Determining an anti-oxidation enzyme activity of a liver of the Koi after exposure; (5) Data analyzing. By comparing the changes of liver enzyme activities in different water, the present method evaluates the toxicity changes of micro-pollutant containing water before and after treatment, which fills in the gap of the ecological risk assessment for advanced oxidation technology.
    Type: Grant
    Filed: June 24, 2018
    Date of Patent: November 29, 2022
    Assignee: NANJING UNIVERSITY
    Inventors: Jinju Geng, Yingying Fu, Xingsheng Gao, Hongqiang Ren
  • Patent number: 11497216
    Abstract: The present invention relates to Podoviridae bacteriophage Pse-AEP-4 (accession number: KCTC 13166BP) isolated from nature, the Podoviridae bacteriophage Pse-AEP-4 having the capability to specifically kill Pseudomonas aeruginosa and having a genome represented by SEQ ID NO: 1, and a method for preventing or treating diseases induced by Pseudomonas aeruginosa by using a composition containing the Podoviridae bacteriophage Pse-AEP-4 as an active ingredient.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: November 15, 2022
    Assignee: INTRON BIOTECHNOLOGY, INC.
    Inventors: Seong Jun Yoon, Soo Youn Jun, Jee Soo Son, Hyoun Rok Paik, Hee Jeong Shin, Sang Hyeon Kang
  • Patent number: 11457635
    Abstract: The present invention relates to Podoviridae bacteriophage Pse-AEP-3 (accession number: KCTC 13165BP) isolated from nature, the Podoviridae bacteriophage Pse-AEP-3 having the capability to specifically kill Pseudomonas aeruginosa and having a genome represented by SEQ ID NO: 1, and a method for preventing or treating diseases induced by Pseudomonas aeruginosa by using a composition containing the Podoviridae bacteriophage Pse-AEP-3 as an active ingredient.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: October 4, 2022
    Assignee: INTRON BIOTECHNOLOGY, INC.
    Inventors: Seong Jun Yoon, Soo Youn Jun, Jee Soo Son, Hyoun Rok Paik, Hee Jeong Shin, Sang Hyeon Kang
  • Patent number: 11458177
    Abstract: The present invention relates to Siphoviridae bacteriophage Ent-FAP-4 (accession number KCTC 12854BP), separated from nature, which is capable of specifically killing Enterococcus faecium and has a genome expressed by sequence number 1, a pharmaceutical composition, which comprises same as an active ingredient, and a method for preventing or treating diseases, induced by Enterococcus faecium, by administering the pharmaceutical composition.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: October 4, 2022
    Assignee: INTRON BIOTECHNOLOGY, INC.
    Inventors: Seong Jun Yoon, Soo Youn Jun, Hyoun Rok Paik, Jee Soo Son, Sang Hyeon Kang
  • Patent number: 11459554
    Abstract: The present invention relates to an enzyme complex which the following (i) to (iv) are combined: (i) chimeric beta-agarase formed by a fusion of beta-agarase and the dockerin module of endo-?-1,4-glucanase-B; (ii) chimeric kappa-carrageenase formed by a fusion of kappa-carrageenase and the dockerin module of endo-?-1,4-glucanase-B; (iii) chimeric anhydro-galactosidase formed by a fusion of anhydro-galactosidase and the dockerin module of endo?-1,4-glucanase-B; and (iv) mini cellulose-binding protein A, and to a method of degrading red algal biomass using the same. According to the present invention, an enzymatic degradation process is applied for the production of agar degradation products, deviating from conventional methods that relied on physical and chemical pretreatment processes.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: October 4, 2022
    Assignee: Korea University Research and Business Foundation
    Inventors: Sung Ok Han, Dae-Hee Kang, Jeong-Eun Hyeon
  • Patent number: 11452745
    Abstract: The present invention generally relates to the field of probiotic bacteria. In particular, it relates to methods for treating or preventing functional GI disorders comprising administering Bifidobacterium longum, such as Bifidobacterium longum ATCC BAA-999.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: September 27, 2022
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Peter McLean, Gabriela Bergonzelli Degonda, Stephen Michael Collins, Premysl Bercik, Elena Verdu de Bercik
  • Patent number: 11421256
    Abstract: The invention relates to a process for the preparation of a fermentation product from ligno-cellulosic material, comprising the following steps: a) optionally pre-treatment b) optionally washing; c) enzymatic hydrolysis; d) fermentation; and e) optionally recovery of a fermentation product; wherein in step c) an enzyme composition is used that has a temperature optimum of 55 degrees C. or more, the hydrolysis time is 40 hours or more and the temperature is 50 degrees C. or more.
    Type: Grant
    Filed: October 17, 2018
    Date of Patent: August 23, 2022
    Assignee: DSM IP ASSETS B.V.
    Inventors: Johannes Petrus Smits, Elisabeth Maria Gierveld, Fop Van Der Hor
  • Patent number: 11412760
    Abstract: The present invention relates to a Myoviridae bacteriophage ESC-COP-7 (accession number KCTC 13130BP) isolated from nature, and a method for preventing and treating infections from pathogenic Escherichia coli by means of a composition containing the Myoviridae bacteriophage ESC-COP-7 as an active ingredient, the Myoviridae bacteriophage ESC-COP-7 being characterized by having the capability to specifically kill Escherichia coli, and genome expressed by the SEQ ID 1.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: August 16, 2022
    Inventors: Seong Jun Yoon, Soo Youn Jun, Hyoun Rok Paik, Jee Soo Son, SAng Hyeon Kang
  • Patent number: 11415513
    Abstract: A method for determining the degree of sensitivity of a strain of fungus to an antifungal agent by using the possible change in a chitin level in a population of cells of a strain of fungus to an antifungal agent. The change is determined compared to the chitin level of a population of cells of said strain of fungus in the absence of antifungal agent.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: August 16, 2022
    Assignees: UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER RÉGIONAL DE GRENOBLE
    Inventors: Delphine Paule Renee Morin-Aldebert, Murielle Monique Jacqueline Cornet-Gigou
  • Patent number: 11391732
    Abstract: A process for capturing or concentrating microorganisms for detection or assay comprises (a) providing a concentration agent that comprises an amorphous metal silicate and that has a surface composition having a metal atom to silicon atom ratio of less than or equal to about 0.5, as determined by X-ray photoelectron spectroscopy (XPS); (b) providing a sample comprising at least one microorganism strain; and (c) contacting the concentration agent with the sample such that at least a portion of the at least one microorganism strain is bound to or captured by the concentration agent.
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: July 19, 2022
    Assignee: 3MInnovative Properties Company
    Inventors: Manjiri T. Kshirsagar, Tushar A. Kshirsagar, Thomas E. Wood
  • Patent number: 11352596
    Abstract: The invention relates to a method for producing biogas from lignocellulose-containing biomass, preferably from straw, and to a plant for carrying out said method.
    Type: Grant
    Filed: December 16, 2013
    Date of Patent: June 7, 2022
    Assignee: VERBIO VEREINIGTE BIOENERGIE AG
    Inventors: Oliver Ludtke, Michael Schlimbach, Enrico Fichter, Jens Horn, Georg Pollert, Jan Kuhling
  • Patent number: 11291711
    Abstract: Subjects of the invention are a method of plasminogen supplementation in a plasminogen-deficient subject, and method for the treatment of plasminogen-deficiency in a plasminogen-deficient subject. These methods comprise administering to the plasminogen-deficient subject a dose of plasminogen, and more particularly Glu-plasminogen, for increasing the subject plasminogen activity level by at least about 1%, and more particularly by at least 10%, of the normal plasminogen activity and for maintaining the plasminogen activity level over a supplementation period or a treatment period. The plasminogen-deficient subject of the present invention may suffer from Type-I, Type-II plasminogen-deficiency or an acquired deficiency.
    Type: Grant
    Filed: November 3, 2016
    Date of Patent: April 5, 2022
    Assignee: PROMETIC BIOTHERAPEUTICS, INC.
    Inventors: Martin Robitaille, Karen Thibaudeau, Pierre Laurin, Stacy Plum