Abstract: Provided is a composition for preventing, alleviating or treating dry eye syndrome, containing an Aucuba japonica extract as an active ingredient. The composition containing an Aucuba japonica extract can be effectively used in the prevention, alleviation or treatment of dry eye syndrome.
Type:
Grant
Filed:
October 30, 2018
Date of Patent:
March 26, 2024
Assignee:
INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY
Abstract: A preparation method of non-ester tea polyphenols rich in EGC. Includes leaching wall-broken crushed tea leaves using endogenous hydrolytic enzymes contained in the tea leaves; refining the leached solution after filtration and concentration and purifying it by mobile leaching-water washing; concentrating and drying the purified product to obtain a non-ester tea polyphenols product rich in EGC, wherein the content of tea polyphenols is 90-99.5%, the content of EGC is greater than 80%, and the content of ester catechins EGCG+ECG is less than 10%.
Abstract: A composition includes Commiphora mukul extract, Camellia sinensis extract, and Trigonella foenum-graecum extract. The composition may further include Allium sativum extract, Zingiber officinale extract, and Cinnamomum verum extract. The composition may include Commiphora mukul extract at about 24%-36% by weight of the total composition, the Allium sativum extract at about 20%-30% by weight of the total composition, the Camellia sinensis extract at about 12%-18% by weight of the total composition, the Trigonella foenum-graecum extract at about 12%-18% by weight of the total composition, the Zingiber officinale extract at about 8%-12% by weight of the total composition, and the Cinnamomum verum extract at about 4%-6% by weight of the total composition. The disclosure further provides methods of treating hyperlipidemia using the disclosed compositions.
Abstract: A composition for decreasing proliferation of cancer cells undergoing hyperthermia therapy is described. Such compositions can include a combination of selenium and fish oil. The respective quantities of selenium and fish oil are provided in amounts effective to synergistically increase the sensitivity of the cancer cells to temperatures in excess of 37° C.
Abstract: The present invention is directed to a therapeutic composition including an active therapeutic ingredient combined with a liquid or solution based carbonated beverage. The invention as described details the use or administration of the therapeutic composition so as to treat a variety of ailments. The present invention is also directed to a method of administering the therapeutic composition to an individual for the purposes of alleviating an ailment. In a further arrangement, the therapeutic composition is provided to a user as a pre-packaged volume containing a single effective dose of the therapeutic agent.
Abstract: The present invention is directed to a therapeutic composition including an active therapeutic ingredient combined with a liquid or solution based carbonated beverage. The invention as described details the use or administration of the therapeutic composition so as to treat a variety of ailments. The present invention is also directed to a method of administering the therapeutic composition to an individual for the purposes of alleviating an ailment. In a further arrangement, the therapeutic composition is provided to a user as a pre-packaged volume containing a single effective dose of the therapeutic agent.
Abstract: A method for reducing the appearance of a skin pore in skin of a subject in need thereof is disclosed. The method can include topically applying to the skin pore a composition comprising effective amount of Albizia julibrissin bark extract, and hydrolyzed soy flour, wherein topical application of the composition reduces the appearance of the size of the skin pore.
Type:
Grant
Filed:
May 13, 2021
Date of Patent:
December 5, 2023
Assignee:
MARY KAY INC.
Inventors:
David Gan, Geetha Kalahasti, Lisha Van Pelt
Abstract: Provided herein is a method of obtaining an extract from a plant biomass as well as an extract obtained from the method. Also provided is a pharmaceutical product, ODF, nutraceutical product, and/or edible product, that includes the extract and one or more excipients. Also provided is a method that includes orally administering the extract (or pharmaceutical product, ODF, nutraceutical product, and/or edible product, that includes the extract).
Type:
Grant
Filed:
March 5, 2021
Date of Patent:
October 31, 2023
Inventors:
Robert Davidson, Vered Gigi, Jose Bernardo
Abstract: The present invention relates to processes for forming eutectic extracts, processes for purifying eutectic extracts and uses of the eutectic extracts such as in food-stuffs, pharmaceuticals, nutraceuticals and supplements, such as food supplements and sports supplements.
Type:
Grant
Filed:
May 15, 2019
Date of Patent:
October 17, 2023
Inventors:
Michaël Laguerre, Robert Harris, Alexis Lavaud, Mathieu Tenon, Simona Birtic, Antoine Charles Bily, Andrew Peter Abbott
Abstract: A pharmaceutical composition comprises a Quisqualis indica extract as an active ingredient, for preventing or treating prostatic hyperplasia, and may also be used in a food composition. The Quisqualis indica extract may be used to treat and prevent prostatic hyperplasia by exhibiting effects of a reduction in prostate weight, a reduction in DHT as a prostatic hyperplasia inducing factor, and a reduction in prostate epithelial cell hyperplasia.
Type:
Grant
Filed:
December 23, 2019
Date of Patent:
October 3, 2023
Assignee:
The Industry & Academic Cooperation in Chungnam National University
Abstract: The present invention relates to the use of cannabidivarin (CBDV) in the treatment of autism spectrum disorder (ASD) and ASD-associated disorders such as Fragile X syndrome (FXS); Rett syndrome (RS); or Angelman syndrome (AS). In a further embodiment the invention relates to the use of CBDV in the treatment of schizophrenia. CBDV has been shown to be particularly effective in improving cognitive dysfunction in rodent models of ASD, FXS, RS, AS and schizophrenia. The CBDV is preferably substantially pure. It may take the form of a highly purified extract of cannabis such that the CBDV is present at greater than 95% of the total extract (w/w) and the other components of the extract are characterised. Alternatively, the CBDV is synthetically produced.
Type:
Grant
Filed:
April 11, 2017
Date of Patent:
September 12, 2023
Assignee:
GW RESEARCH LIMITED
Inventors:
Geoffrey Guy, Stephen Wright, James Brodie, Marie Woolley-Roberts, Rafael Maldonado, Daniela Parolaro, Livio Luongo, Joanna Neill
Abstract: Disclosed are an Inonotus Obliquus dextran, a preparation method and application thereof, and relates to the field of medicines. The dextran has a structural formula as follows: By optimizing the extraction and isolation process, the present disclosure obtains an Inonotus Obliquus dextran, which is structurally determined to be a new polysaccharide. The Inonotus Obliquus dextran prepared by the present disclosure is combined with gemcitabine hydrochloride to inhibit tumor cells with anti-tumor activity against pancreatic cancer, in addition to reduce the dosage of chemotherapeutic drugs as well as the adverse effects of chemotherapeutic drugs.
Abstract: A ginseng candy composition having effect of nourishing the body, strengthen the immune system, antibacterial, antiviral related to the respiratory tract, and SARS-CoV-2 virus-neutralizing efficacy of betel leaf extract/essential oil was increased by the combination with the one or two or more plant extracts/essential oils ingredients, 4-allylpyrocatechol (APC) ingredient, a ginseng extract ingredient, and ingredients other by predefined order and predetermined percentage by weight of each ingredient; wherein the plant extracts/essential oils ingredients including chinese liquorice (Glycyrrhiza uralensis Fisch.), liquorice (Glycyrrhiza Glabra L.), mint (Mentha haplocalyx Briq.), lemongrass (Cymbopogon citratus, Cymbopogon winterianus J., Cymbopogon flexuosus Stapf.).
Abstract: A betel leaf extracts composition having bactericidal, antiviral, and neutralization of virus SARS-CoV-2 properties by oral. The bactericidal, antiviral, and SARS-CoV-2 virus-neutralizing efficacy of betel leaf extract/essential oil was increased by the combination with the one or two or more active plant extracts/essential oils ingredients, 4-allylpyrocatechol (APC) ingredient, a mixture of ginger-honey, and a mixture of lemon-kumquat-cinnamon by predefined order and predetermined percentage by weight of each ingredient into an oral cavity delivery agent including a range of gum, confectionery/candy, lozenge, tablet, edible film, oral film, oral solution and oral spray solution.
Abstract: The subject invention provides compositions and methods for treating human dermatological conditions by employing a microbiome-centered treatment approach. Preferred embodiments of the invention provide pharmaceutical and cosmetic compositions, and the methods of using the same, comprising a strain of Lactobacillus fermentum bacterium, or bioactive extracts thereof, derived from human microbiota and capable of growing in biofilm phenotype.
Type:
Grant
Filed:
March 2, 2020
Date of Patent:
January 31, 2023
Assignee:
QUORUM INNOVATIONS, LLC
Inventors:
Eva A. Berkes, Nicholas T. Monsul, Frederick T. Boehm
Abstract: The present invention relates to a method for controlling fungal phytopathogens using Galla chinensis preparations, and to a fungicidal composition comprising Galla chinensis in combination with at least one phytologically acceptable adhesive.
Abstract: Provided herein is a substance for use in a therapeutic method for stimulating cells in the human immune system, a method for producing this substance, and a method of use of the substance for stimulating cells of the human immune system in treating various diseases involving immune system disorders.
Type:
Grant
Filed:
August 25, 2020
Date of Patent:
December 27, 2022
Assignee:
Vita Motus AG
Inventors:
Aleksandr Abramov, Alisa Petkevic, Vadim Pospelov
Abstract: The present invention relates to a method of treating acute or chronic systemic graft-versus-host disease (GVHD) with extracellular vesicles, e.g., exosomes obtained from human cardiospheres or cardiosphere-derived cells (CDCs), wherein systemic GVHD involves, e.g., at least two organs selected from the group consisting of the skin, mucosa, gastrointestinal tract, liver, lungs, joints and fascia, genitalia, and eyes. The present invention also provides a pharmaceutical formulation comprising extracellular vesicles, e.g., exosomes obtained from human cardiospheres or CDCs, for systemic administration, e.g., intravenous infusion, to a human subject in need of treatment of systemic GVHD.
Type:
Grant
Filed:
May 4, 2018
Date of Patent:
December 20, 2022
Inventors:
Luis Rodriguez-Borlado, Houman Hemmati, Kiel A. Peck, Linda Marban, Jennifer J. Moseley
Abstract: Present invention discloses an oil palm composition for use in prevention or treatment of Alzheimer's disease. The composition is useful in impeding formation of neurotoxic peptide. Present invention can be used in preparation of a medicament in a therapeutic effective amount for prevention or treatment of Alzheimer's disease and diseases related thereto.
Type:
Grant
Filed:
July 10, 2019
Date of Patent:
December 6, 2022
Assignee:
MALAYSIAN PALM OIL BOARD
Inventors:
Robert P. Weinberg, Chokyun Rha, Anthony J. Sinskey, Yew Ai Tan, Ravigadevi Sambanthamurthi
Abstract: A method to prepare a therapeutic balm is disclosed. A first phase solution is prepared in an oak barrel using a grain neutral spirit. The first phase is mixed for 10 minutes per day for a month to prepare a second phase solution. The second phase solution is filtered at least twice to prepare a filtrate. The filtrate and third phase components are mixed to prepare a third phase solution. The third phase solution is mixed with a distilled wine liquor to prepare a fourth phase solution. The fourth phase solution is mixed at least twice a day for a month to prepare a fifth phase solution. The fifth phase solution is mixed with cranberry juice, pomegranate juice, and raspberry juice to prepare a sixth phase solution. The sixth phase solution is stored in a ceramic bottle for a least six months at room temperature to prepare a therapeutic balm.