Abstract: A multi-layered beauty care product is provided. The beauty care product has a layer of a water-soluble film zone with a water-soluble film forming polymer and a cosmetic composition with a skin active agent. The product also has a vapor-deposited coating. The vapor-deposited coating is a poly(p-xylylene) polymer and/or a metal oxide inorganic coating.

Abstract: A hydrogen-containing composition for ingestion or topical use and method of producing the hydrogen-containing composition are provided. The composition includes a carrier liquid and molecular hydrogen. The concentration of molecular hydrogen in the carrier liquid is greater than 3 ppm.

Abstract: The present invention concerns methods of administering a therapeutically effective dose of a sorbent for an inflammatory mediator to a patient where the inflammatory mediator is one or more of enzymes, cytokines, prostaglandins, eicosanoids, leukotrienes, kinins, complement, coagulation factors, endotoxins, enterotoxins, lipopolysaccharide, cell fragments, bile salts, fatty acids, phospholipids, interferon and immunomodulatory antibodies, biologics or drugs.

Abstract: Improved oral dosage forms of methyl hydrogen fumarate and prodrugs thereof are disclosed. Methods of treating diseases such as multiple sclerosis and psoriasis using such dosage forms are also disclose.

Abstract: Disclosed is a long wearing cosmetic product with elegant glide and feel with cooling sensation and impactful color intensity with high coverage. The disclosed combination of a silicone resin, an ethylenic polymer including a monomer having a bicyclic group, and a taurate copolymer provides a flexible/soft film on eye lids which is not brittle and wears longer for hours.

Abstract: [Object] The present invention aims to provide an external dermal agent that tightens the skin, lifts up sagging skin, has no stickiness to the skin, and has a satisfactory compatibility with the skin, without giving any unfavorable feeling to users. [Means to Attain the Object] The present invention solves the above object by providing an external dermal agent characterized in that it contains pullulan and an alkaline-swelling polymer in a mass ratio of the pullulan to the alkaline-swelling polymer being 10 or more.

Abstract: The invention relates to a composition comprising: (a) one or more alkoxysilanes comprising solubilizing function(s) of formula R1Si(OR2)z(R3)x(OH)y, and/or hydrolysis products thereof and/or oligomers thereof, (b) one or more of formula (R4)mSi(OR5)n and/or hydrolysis products thereof and/or oligomers thereof, et (c) one or more surfactants. It also relates to the use thereof for cleansing and/or conditioning keratin fibres.

Abstract: A Direct Sodium Removal method, apparatus and solution for treating patients in heart failure, and having a glomerular filtration rate greater than 15 mL/min/1.73 m2, or residual kidney function corresponding to normal to CKD Stage 4, is provided in which a no or low sodium DSR infusate is administered to the peritoneal cavity for a predetermined dwell period and then removed, thereby removing sodium from the body. The resulting elimination of fluid from the patient by i) functioning of the kidneys through urination and ii) direct removal of osmotic ultrafiltrate from the peritoneal cavity, restores serum sodium concentrations to healthy levels and thereby reduces fluid overload in the patient.

Abstract: Food processing equipment, food contact surfaces, and non-food contact surfaces are sanitized or disinfected using an acid-anionic surfactant solution that has efficacy in hard water, is non-corrosive, and is stable at elevated temperatures. The sanitizing/disinfecting solution is prepared as a highly concentrated liquid and diluted to end use concentrations prior to application to food processing equipment or food or non-food contact surfaces. Efficacy in hard water is important for sanitizers and disinfectants that are diluted by the end user using potentially hard water. Stability at elevated temperatures is important for long-term storage and transportation. The diluted sanitizing/disinfecting solution exhibits strong antimicrobial activity against gram positive and gram negative bacteria even when diluted in hard water. The sanitizing/disinfecting solution exhibits low toxicity to humans and the environment since it is prepared from low toxicity ingredients that are readily biodegradable.

Abstract: An antibiotic-eluting article for implantation into a mammalian subject, produced by an additive manufacturing process wherein a polymeric material is concurrently deposited with a selected antibiotic. The additive manufacturing process may be a fused deposition modeling process, a selective laser sintering process, a selective heat sintering process, a digital light processing process, or a stereolithography process. The antibiotic-eluting article may be temporary or permanent orthopaedic skeletal component, an orthopaedic articulating joint replacement component, and/or an external hard-shell casing for an implantable device. One or more bone-growth-promoting compositions may be concurrently deposited with the polymeric material.

Abstract: The present invention relates to microcapsules formed by interfacial polymerization, which present high deposition properties and which can be advantageously used for example in the perfumery industry. Perfuming compositions and perfumed consumer products comprising these microcapsules are also objects of the invention.

Abstract: A Direct Sodium Removal method, apparatus and solution for treating patients in heart failure, and having a glomerular filtration rate greater than 15 mL/min/1.73 m2, or residual kidney function corresponding to normal to CKD Stage 4, is provided in which a no or low sodium DSR infusate is administered to the peritoneal cavity for a predetermined dwell period and then removed, thereby removing sodium from the body. The resulting elimination of fluid from the patient by i) functioning of the kidneys through urination and ii) direct removal of osmotic ultrafiltrate from the peritoneal cavity, restores serum sodium concentrations to healthy levels and thereby reduces fluid overload in the patient.

Abstract: The present invention relates to a composition in the form of an O/W emulsion, comprising: (a) at least one UV filter; (b) at least one inulin or inulin modified with hydrophobic chains; (c) at least one sugar ether surfactant; (d) at least one hydrophilic acrylic polymer; and (e) water. The composition according to the present invention can provide a homogeneous film when being applied, and good cosmetic effects such as superior UV filtering effects, while providing a watery fresh feeling during the application and a non-sticky feeling after the application.

Abstract: The present invention relates to a drug-eluting medical device, in particular a balloon for angioplasty catheters with drug elution to prevent the restenosis of the vessel subjected to angioplasty. More particularly, the present invention relates to a catheter balloon completely or partially coated with paclitaxel in hydrated crystalline form or in hydrated solvated crystalline form, having an immediate release and bioavailability of a therapeutically effective amount of paclitaxel at the site of intervention. The balloon can be made of a polyether-polyamide block copolymer, or a polyester amide, or polyamide-12.

Abstract: The invention relates to a preparation containing at least one compound of formula (I), providing that R1 is H or CH3 and R2 is II or COOII, or salts thereof, to be used as a drug for preventing and/or treating signs of degeneration and ageing of the skin which are not, or not exclusively, caused by the effect of light.

Abstract: A food composition for managing non-food allergies in companion animals is disclosed, along with a method of managing non-food allergies.

Abstract: Compositions containing a biologically active material and a non-ordered inorganic oxide material are disclosed. Methods of making and using compositions containing a biologically active material and a non-ordered inorganic oxide material are also disclosed.

Abstract: Disclosed are compositions, methods and processes for fabricating and using a device or other implement including a surface or surfaces having a nanoscale or microscale layer or coating of Si—O—N—P. These coatings and/or layers may be continuous, on the surface or discontinuous (e.g., patterned, grooved), and may be provided on silica surfaces, metal (e.g., titanium), ceramic, and combination/hybrid materials. Methods of producing an implantable device, such as a load-bearing or non-load-bearing device, such as a bone or other structural implant device (load-bearing), are also presented. Craniofacial, osteogenic and disordered bone regeneration (osteoporosis) uses and applications of devices that include at least one surface that is treated to include a nanoscale or microscale layer or coating of Si—O—N—P are also provided. Methods of using the treated and/or coated devices to enhance enhanced vascularization and healing at a treated surface of a device in vivo, is also presented.

Abstract: The disclosure provides cosmetic and therapeutic compositions of alpha-adrenergic agents. Compositions of the disclosure may be used for topical, transdermal or parenteral administration to the eye or eyelid. The compositions of the disclosure may be used cosmetically to improve the appearance of the eye or therapeutically to treat ptosis.

Abstract: Methods of treating patients suffering from non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), including those also suffering from type II diabetes mellitus (T2DM), with a delayed release pharmaceutical composition comprising 6-mercaptopurine are disclosed.