Abstract: A hair-dyeing composition that minimizes hair damage and scalp irritation caused by applying ammonia to the scalp and that reduces the ammonia odor peculiar to hair-dyeing compositions is provided. The hair-dyeing composition additionally supplements the hair with amino acids similar to hair proteins to decrease hair damage, especially hair roughness and hair shortening, for healthy dyeing. A method of producing the hair-dyeing composition is additionally provided and includes melting, mixing, and emulsifying steps.
Abstract: The instant disclosure relates to hair-treatment compositions that include a unique combination of components that function to impart desirable cosmetic properties to the hair, especially chemically treated hair. The hair-treatment compositions typically include: at least 0.5 wt. % of at least one non-polymeric mono, di, or tricarboxylic acid, and/or a salt thereof; one or more amines; one or more alkoxysilanes; one or more cationic polymers; and water. Hair treated with the hair-treatment compositions is strengthened and exhibits improved sensorial properties such as smoothness, softness, and suppleness.
Type:
Grant
Filed:
May 24, 2017
Date of Patent:
March 3, 2020
Assignee:
L'OREAL
Inventors:
Kwana Patterson, Barbara Mitchell, Anand Mahadeshwar
Abstract: A disinfecting composition comprising a quaternary ammonium acid compound and hydrogen peroxide is disclosed. An embodiment of the composition comprises a quaternary ammonium acid compound in a hydrogen peroxide/water solution. In addition, the composition can further comprise an acid. In addition, the composition does not comprise a cationic polymer. The disclosure also provides methods of using the same to kill or inhibit the growth of microorganisms, such as bacteria, viruses, fungi, mildew, and mold. The disclosure also provides for methods of disinfecting a substrate, preferably a hard surface, comprising applying a disinfecting composition of the invention to the substrate.
Type:
Grant
Filed:
January 10, 2019
Date of Patent:
February 25, 2020
Assignee:
LONZA INC.
Inventors:
Marcus Bentley, Andrew Colurciello, Danuel Brown
Abstract: Food processing equipment, food contact surfaces, and non-food contact surfaces are sanitized or disinfected using an acid-anionic surfactant solution that has efficacy in hard water, is non-corrosive, and is stable at elevated temperatures. The sanitizing/disinfecting solution is prepared as a highly concentrated liquid and diluted to end use concentrations prior to application to food processing equipment or food or non-food contact surfaces. Efficacy in hard water is important for sanitizers and disinfectants that are diluted by the end user using potentially hard water. Stability at elevated temperatures is important for long-term storage and transportation. The diluted sanitizing/disinfecting solution exhibits strong antimicrobial activity against gram positive and gram negative bacteria even when diluted in hard water. The sanitizing/disinfecting solution exhibits low toxicity to humans and the environment since it is prepared from low toxicity ingredients that are readily biodegradable.
Type:
Grant
Filed:
August 9, 2018
Date of Patent:
February 25, 2020
Assignee:
ProNatural Brands, LLC
Inventors:
William Salminen, Gary Russotti, Richard Aab, Robert Tuchrelo, Jeffrey Cahoon
Abstract: Described herein are compositions comprising shortened fibers of poly-N-acetylglucosamine and/or a derivative thereof (“sNAG nanofibers”) and anti-bacterial applications of such compositions. The sNAG nanofibers may be formulated into compositions for the prevention and/or treatment of bacterial infections and diseases associated with such infections. Regimens employing such compositions are also described.
Type:
Grant
Filed:
December 21, 2018
Date of Patent:
February 18, 2020
Assignee:
Marine Polymer Technologies, Inc.
Inventors:
John N. Vournakis, Sergio Finkielsztein
Abstract: Compositions and methods for repelling coleopterans. The compositions contain a substrate and an anti-aggregation pheremone intermixed within the substrate. The pheremone may be verbenone, methyl salycylate, wintergreen oil, or combinations thereof.
Type:
Grant
Filed:
May 12, 2017
Date of Patent:
January 28, 2020
Inventors:
Agenor Mafra-Neto, Josue Isaias Ponce, William H. Urrutia, Carmem R. Bernardi, Rodrigo Oliveira Da Silva
Abstract: The present invention relates to topical compositions comprising 10-hydroxystearic acid or a salt thereof in combination with 12-hydroxystearic acid or a salt thereof. The present invention also relates to a method to retard or inhibit the recrystallization of 10-hydroxystearic acid or a salt thereof in a topical composition, said method comprising formulating 10-hydroxystearic acid or a salt thereof in the presence of 12-hydroxystearic acid or a salt thereof.
Abstract: Nanoparticles comprising a metal oxide and a platinum cluster having a height to base ratio greater than 1 and compositions containing the same are disclosed. Methods of using the nanoparticles in producing hydroxyl radicals and in photodynamic therapy, for example, in the treatment of hyperproliferative disease such cancer, are also disclosed.
Type:
Grant
Filed:
April 24, 2015
Date of Patent:
November 5, 2019
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
Abstract: The invention relates to a polysaccharide polymer of formula (I): PS—(O—CO-L-X)a(OH)b??(I) in which PS denotes the basic backbone of the polysaccharide bearing the hydroxyl groups; L is a divalent hydrocarbon-based group comprising from 1 to 20 carbon atoms; X denotes a photoactive group of azide or diazirine type; a denotes the content of OH groups substituted with the photoactive group; b denotes the content of unsubstituted free OH groups; a being between 0.02 and 0.5; b being between 0.5 and 0.98; and a+b=1. The invention also relates to a composition comprising the polymer (I) in a physiologically acceptable medium, and also to a cosmetic process for caring for the skin, comprising the topical application to the skin of said composition and exposure of the treated skin to light radiation.
Abstract: The present disclosure relates to a taste-masking microcapsule composition. The composition comprises a core portion encapsulated by a shell portion. The core portion comprises an active pharmaceutical ingredient (API) and one or more excipients. The shell portion comprises a hydrophobic matrix and a pH-responsive material. The microcapsule compositions prevent API release at the more neutral pH levels in the oral cavity, but upon exposure to pH levels of the stomach, the pH-responsive material becomes soluble thereby permitting release of the API.
Abstract: A dry urine-based scent lure is provided for hunting. The lure includes an absorbent member impregnated with liquid urine, and then freeze dried to remove moisture from the host member. The urine maybe a blended mixture from different animals so as to have desired properties. The urine is concentrated and then infused into the absorbent material, which is then flash frozen, followed by freeze drying. The resulting dry scent lure is packaged so as to seal out humidity, and produce a lure with unlimited shelf life.
Abstract: Disclosed is an adhesive patch having a support and an adhesive agent layer laminated on the support, wherein the support consists of spunlace nonwoven fabric, the adhesive agent layer comprises an SIS block copolymer and liquid paraffin, the adhesive patch has a first direction, which is a predetermined reference axis direction, and a second direction, which is orthogonal to the first direction, and a bending resistance in the first direction of the adhesive patch is 18 to 30 mm.
Abstract: A dosage form comprising a capsule containing one or more tablets of 5-aminosalicylic acid or a salt thereof as an active ingredient where each of the one or more tablets is enterically coated is disclosed.
Type:
Grant
Filed:
September 2, 2014
Date of Patent:
April 23, 2019
Assignee:
ALLERGAN PHARMACEUTICAL INTERNATIONAL LIMITED
Inventors:
Emma Boyd, Deborah Leigh Caldwell, Catherine Coulter, Ryan Loughlin, Stephen McCullagh
Abstract: The present invention in general relates to a pharmaceutical suspension comprising nano-sized cocrystals of at least one active ingredient and at least one dicarboxylic acid. It in particular relates to a pharmaceutical suspension comprising nano-sized cocrystals of at least one anthelmintic drug and at least one dicarboxylic acid. The invention further relates to uses, methods for use and methods for manufacturing the pharmaceutical suspension according to this invention.
Abstract: Synthesis and characterization of starch based pH-responsive nanoparticles for controlled drug delivery are described. Polymethacrylic acid grafted starch (PMAA-g-St) nanoparticles with various molar ratio of starch to MAA were synthesized by a new one-pot method that enabled simultaneous grafting of PMAA and nanoparticle formation in an aqueous medium. NMR data showed that polysorbate 80 was polymerized into the graft polymer. Nanoparticles were relatively spherical with narrow size distribution and porous surface morphology and exhibited pH-dependent swelling in physiological pH range. The particle size and magnitude of volume phase transition were dependent on PMAA content and formulation parameters such as surfactant levels, cross-linker amount, and total monomer concentration. The results showed that the new pH-responsive nanoparticles possessed useful properties for controlled drug delivery.
Type:
Grant
Filed:
March 4, 2013
Date of Patent:
March 19, 2019
Assignee:
The Governing Council of the University of Toronto
Abstract: Disclosed are pulverulent compositions of a complex between an acid and a metal, having a high organosulfur compound content, and method for preparing same.
Type:
Grant
Filed:
March 21, 2016
Date of Patent:
March 12, 2019
Assignee:
INNOV'IA 3I
Inventors:
Pierre Buisson, Robert Huet, Sebastien Fournier, Jean-Eudes Vendeville
Abstract: Described herein are compositions comprising shortened fibers of poly-N-acetylglucosamine and/or a derivative thereof (“sNAG nanofibers”) and anti-bacterial applications of such compositions. The sNAG nanofibers may be formulated into compositions for the prevention and/or treatment of bacterial infections and diseases associated with such infections. Regimens employing such compositions are also described.
Type:
Grant
Filed:
March 31, 2017
Date of Patent:
February 19, 2019
Assignee:
Marine Polymer Technologies, Inc.
Inventors:
John N. Vournakis, Sergio Finkielsztein
Abstract: A stable dry powder composition for inhalation includes acetylsalicylic acid in particles having a mass median aerodynamic diameter (MMAD) in a range of about 1 ?m to about 5 ?m. The dry powder composition may contain a pharmaceutically acceptable excipient, such as a stearate, in an amount ranging from about 0.04% (w/w) to about 0.06% (w/w), or from about 0.4% (w/w) to about 0.6% (w/w), of the composition.
Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, malic acid, an oxidant, and water, is provided along with temperature conditions to directly form within the reaction mixture, a stable dispersion of nanoceria particles. Biocompatible nanoparticles comprised of ceria and malic acid are described. A reduction in cell death in a murine model of ischemic stroke utilizing intact brain slices is demonstrated by a prophylactic treatment of ceria nanoparticles prepared with malic acid.
Abstract: The present invention relates to a nanoemulsion for transdermal delivery. The presently claimed invention provides chemical formulations for preparing a nanoemulsion, and the methods for preparing the nanoemulsion. The nanoemulsion has desirable particle size for efficient transdermal delivery, and doesn't involve any organic solvent which is harmful to human skin. The corresponding fabrication method is simple.
Type:
Grant
Filed:
February 17, 2015
Date of Patent:
November 27, 2018
Assignee:
Nano and Advanced Materials Institute Limited
Inventors:
Ngar Yee Huen, Sau Kuen Connie Kwok, Jinjie Xu, Chun Him Wong, Min Xiao