Patents Examined by Rebecca E Eisenberg
  • Patent number: 11224697
    Abstract: The invention relates to an injection unit, preferably a pen-shaped injection unit, for administering or delivering a fluid product. The injection unit comprises a housing, an axially movable piston rod mounted in the housing in a non-rotatable manner, a delivery apparatus having a threaded nut that is able to move the piston rod in order to deliver product, a dosing device having a dosing sleeve, a rotary knob, a discharge button arranged coaxially on the dosing sleeve, and a receptacle for the product. The dosing device is connected to the delivery apparatus via a coupling mechanism, wherein the coupling mechanism includes of at least two coupling surfaces that each carry a toothing comprising teeth, wherein the coupling surfaces are used to generate an acoustic and/or tactile signal corresponding to the set or corrected dose of the product to be administered during the dosing operation or during correction of the dose.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: January 18, 2022
    Assignee: Ypsomed AG
    Inventors: Juerg Hirschel, Ulrich Moser, Stefan Burren
  • Patent number: 11219746
    Abstract: Disclosed herein are steerable catheter assemblies that utilize various mechanisms to accomplish independent control of catheter flex magnitude and catheter flex direction to provide improved steerability of an attached catheter. Some embodiments include a catheter with two or more pull wires that flex the catheter and a control handle coupled to the catheter. The control handle can include a direction control coupled to the two or more pull wires such that adjustment of the direction control adjusts a direction of catheter flex by the two or more pull wires, and the control handle can include a magnitude control coupled to the two or more pull wires such that adjustment of the magnitude control adjusts the magnitude of catheter flex.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: January 11, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Bao Khuu, Matthew T. Winston, Asher L. Metchik, Eric Robert Dixon
  • Patent number: 11213621
    Abstract: A fluid therapy method for an ADHF patient includes setting a urine output rate desired threshold, setting one or more desired negative net gain rates, and optionally setting a total fluid loss goal. The urine output of the patient is monitored and fluid is automatically administered to the patient at increasing rates to equal to or approximately match the patient's increasing urine output rates until the patient's urine output rate reaches the set urine output rate desired threshold. Thereafter, fluid is administered to the patient at rates to achieve the set desired negative net gain rate until the fluid loss goal is reached. Thereafter, until the end of therapy, fluid is administered to the patient at rates equal to or approximately equal to the monitored urine output rates.
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: January 4, 2022
    Assignee: Reprieve Cardiovascular, Inc.
    Inventors: Andrew V. Halpert, Mark Tauscher, Mark Gelfand, Howard Levin
  • Patent number: 11207467
    Abstract: The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: December 28, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
  • Patent number: 11202892
    Abstract: An intravascular balloon catheter device for treating various size stenosed regions within a blood vessel is provided. A clamp located within a body of a handle assembly is movable between a clamped and unclamped position by way of a button. When clamped, an outer member is secured relative to a sheath to as to expose a portion of a balloon located on a distal end of the outer member. The portion of the balloon remaining within the sheath is restricted from inflation beyond the sheath.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: December 21, 2021
    Inventor: John P. Pigott
  • Patent number: 11197961
    Abstract: Flush syringe assemblies capable of creating pulsatile movement of the plunger rod as it moves in the distal direction within a syringe barrel, while preventing overpressurization of the catheter are provided. An exemplary flush syringe assembly includes a syringe barrel with a first pulsing element and a chamber with flush solution, a plunger rod with a stopper and a second pulsing element that interacts with the first pulsing element to provide an engagement force that causes pulsatile movement of the plunger rod and a thumb press slidably attached to the plunger rod with a pulse control element. The pulse control element is compressible to create a compression force that is greater than the engagement force of the first pulsing element and the second pulsing element.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: December 14, 2021
    Assignee: Becton, Dickinson and Company
    Inventors: Anthony J. Kosinski, Girum Yemane Tekeste, Nichola Charles
  • Patent number: 11191927
    Abstract: An example dilator is disclosed. The example dilator includes a hub and an elongate shaft having a distal end region, a proximal end region and a cross-sectional profile. Additionally, the proximal end region of the elongate shaft is coupled to the hub and the elongate shaft is configured to extend through at least a portion of a lumen of an expandable introducer sheath. Additionally, the cross-sectional profile of the elongate shaft includes at least one engagement portion and at least a portion of the expandable introducer sheath extends into the at least one engagement portion of the dilator.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: December 7, 2021
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Cathal Joseph McLaughlin, James M. Anderson, Roger W. McGowan, Gregory Dyer, Erik Joseph Haun, Shawn M. Wignall
  • Patent number: 11191937
    Abstract: A method for delivering drugs into cystic fluid, the method comprising injecting a drug delivery system (DDS) into a cystic fluid space at an injection site, the DDS comprising at least one therapeutic agent encapsulated in biodegradable polymers, applying ultrasonic energy proximal to the injection site, and controlling the at least one of buoyancy, delivery location, mixing, and dispersion of the DDS to a targeted area using the ultrasonic energy.
    Type: Grant
    Filed: March 21, 2019
    Date of Patent: December 7, 2021
    Assignee: Advanced CSF Therapies, LLC
    Inventors: Jae H. Choi, Keith Baker, Alexander Klose, John Pile-Spellman
  • Patent number: 11191700
    Abstract: An aseptic connector assembly includes a body portion having a receptacle configured to receive a corresponding fill connector. A pivot portion is movably coupled to the body portion, the pivot portion having a channel formed therein. A conduit portion is slidably disposed within the channel formed in the pivot portion. The pivot portion has a ready position and an operative position, the pivot portion being adjustable from the ready position to the operative position via relative movement with respect to the body portion.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: December 7, 2021
    Assignee: Advanced Scientifics, Inc.
    Inventor: Rudolf Pavlik
  • Patent number: 11185673
    Abstract: A micro-needle array unit includes a micro-needle array; a container which accommodates the micro-needle array and includes an accommodating portion having an opening and a protrusion that supports the outer peripheral surface of the micro-needle array, a deformation portion disposed on a side opposite to the opening and integrated with the accommodating portion, and a flange portion integrated with the accommodating portion and brought into contact with the skin; and a lid which seals the opening of the container, in which the deformation portion is deformed and the other surface of the micro-needle array is pressed due to an external force being applied in a direction of the opening, the micro-needle array deforms the protrusions and is pushed to the outside from the accommodating portion by the pressing of the other surface of the micro-needle array, and the deformation portion maintains the deformed state and presses the micro-needle array.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: November 30, 2021
    Assignee: FUJIFILM Corporation
    Inventor: Yuka Kobayashi
  • Patent number: 11173288
    Abstract: A non-compliant medical balloon comprises a base balloon including a pair of spaced-apart, generally conical end sections and a generally cylindrical center section connected therebetween. A braided fabric sleeve surrounds at least a portion of the base balloon, wherein the sleeve is formed of at least three substantially inelastic fibers intertwined in such a way that no two of the three fibers are twisted exclusively around one another. The sleeve is permanently affixed to the outer surface of the base balloon so as to prevent excessive expansion of the base balloon when the base balloon is internally pressurized.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: November 16, 2021
    Inventors: William F. Davies, Jr., Lanny R. Pepper, Kelli Hayes
  • Patent number: 11166730
    Abstract: Various systems and methods are provided for reducing pressure at an outflow of a duct such as the thoracic duct or the lymphatic duct. In one embodiment, an indwelling catheter can be configured to be at least partially implanted within a vein of a patient in the vicinity of an outflow port of a duct of the lymphatic system. The catheter can include first and second restrictors each configured to at least partially occlude the vein within which the catheter is implanted and thus to restrict fluid flow within the vein when the restrictors are activated. The restrictors can each be configured to move between an activated configuration, in which the restrictor occludes the vein, and a relaxed configuration, in which the restrictor does not occlude the vein. The catheter can include a pump, such as an axial motor pump, configured to pump fluid through the catheter.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: November 9, 2021
    Assignee: White Swell Medical Ltd
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Patent number: 11167085
    Abstract: Embodiments include a syringe-based apparatus for delivering fluid, the apparatus comprising a housing having an open proximal end and a distal end defining an inner volume, a needle, an actuator mechanism coupled with the housing, the actuator mechanism comprising a syringe body and a plunger, a medicament reservoir, and a reconstitution fluid reservoir.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: November 9, 2021
    Inventor: Michael Hopkins
  • Patent number: 11167086
    Abstract: An autoinjector including a syringe, a driver for driving the plunger of the syringe and a stabilizing adaptor for holding the injector on the skin of a patient is provided. The stabilizing adaptor has an adhesive base with a long axis to short axis ratio of at least 1.5 to 1. The syringe is orientated with its axis at an angle of between 60 and 120 degrees to the base during operation of the autoinjector.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: November 9, 2021
    Assignee: West Pharma. Services IL, Ltd.
    Inventors: Oz Cabiri, Ran Hezkiahu
  • Patent number: 11160924
    Abstract: A fluid infusion system includes an air pump connected to an accumulator tank to produce pressurized air that is stored in the accumulator tank. The system can include one or more fluid bag chambers wherein each fluid bag chamber includes an inflatable bladder positioned inside the fluid bag chamber to apply pressure on the fluid bag supported inside the chamber. The fluid bag can be connected by a tube set to deliver fluid from the fluid bag to a surgical tool at a surgical site. The fluid can, for example, be irrigation fluid or distention fluid. The system can include a controller connected to the pump to control the pump to produce the pressurized air and an adjustable pressure regulator can be connected between the accumulator tank and the inflatable bladder to control the pressure of air delivered to the inflatable bladder and the pressure that the fluid is delivered to the surgical tool.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: November 2, 2021
    Assignee: Covidien LP
    Inventors: Peter Boyle, Keith Isaacson, Seth Traub, Craig Traub
  • Patent number: 11160952
    Abstract: Catheters and methods for supporting a guidewire or delivering a radiopaque, diagnostic or therapeutic agent through a vessel stenosis or other tortuous anatomy are disclosed. A catheter can comprise an elongate shaft body and a tip member disposed at a distal end of the shaft body. The shaft body can extend from a proximal end to the distal end and can define an inner lumen. The shaft body can include a liner, a braid member surrounding the liner, a multi-layer coil surrounding the braid member, and a polymer cover surrounding the multi-layer coil. An outer surface portion of the polymer cover can include one or more helical threads, which can be enveloped in an outer wrapper. The tip member can be made from a metal or a polymer. Polymer tip members can include a hard or semi-hard distal tip.
    Type: Grant
    Filed: February 4, 2019
    Date of Patent: November 2, 2021
    Assignee: Teleflex Life Sciences Limited
    Inventors: John Bridgeman, Daniel Jindra, Peter Bo
  • Patent number: 11154422
    Abstract: Eliminating leaks of molded fluid channels by providing a front housing, rear housing, and a gasket, wherein the front housing has one or more molded fluid channels and one or more seal channels, and wherein at least a portion of the gasket is located between the front and rear housing; molding the gasket onto the rear housing to create a single unit, wherein the gasket has one or more seal lips configured and dimensioned to couple with the one or more seal channels; and assembling the front housing to the rear housing having the gasket, wherein the one or more seal lips couple with the seal channels. A surgical cassette manifold having a front and rear housing, and a gasket therebetween. The front housing having molded fluid channels that mate with the gasket and the gasket having multiple valves and a sensor/diaphragm accessible through the rear housing.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: October 26, 2021
    Assignee: Johnson & Johnson Surgical Vision, Inc.
    Inventors: Mark W. Ross, James B. Gerg
  • Patent number: 11154694
    Abstract: An intravascular catheter device includes a handle assembly, an inner member which accommodates a guide wire, an outer member disposed about the inner member, and a balloon. A proximal end of the balloon is attached to a distal end of the outer member. The balloon surrounds a portion of the inner member and the distal end of the balloon is attached to a distal end of the inner member. A sheath is selectively disposed about, and adapted for movement relative to, the balloon. A clamp at the handle assembly selectively secures the outer member at a number of positions relative to the sheath to selectively expose a variable portion of the balloon for movement into an inflated state. A balloon recapture device is located at a distal end of the sheath and aids the balloon in reentering the sheath following deployment.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: October 26, 2021
    Inventor: John P. Pigott
  • Patent number: 11154693
    Abstract: An intravascular balloon catheter device is disclosed having an inner member, an outer member disposed about the inner member and further comprising a balloon. A sheath is disposed about the outer member that moves relative to the balloon so as to selectively expose a first portion of the balloon for inflation. A clamp may be used to selectively secure the sheath at a desired position relative to the balloon wherein the desired position is less than full retraction such that a second portion of the balloon remains within the sheath.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: October 26, 2021
    Inventor: John P. Pigott
  • Patent number: 11147905
    Abstract: A pump apparatus and method for extracting breastmilk is disclosed. A pump head comprises a funnel-shaped breast shield portion and a neck portion leading to a collection container. A deformable elastic component is sealed within an opening formed in the neck portion and manipulated to engage the user's nipple to simulate the suckling of an infant. The deformable elastic component is configured to move into the interior volume of the neck portion under an applied positive pressure to compress the nipple and control nipple edema. The deformable elastic component is also configured to move away from the axial center of the neck portion under an applied negative pressure to create suction and extract breastmilk in a manner that closely replicates the suckling of an infant. The pump may also include another deformable elastic component to stimulate a Milk Ejection Reflex (MER).
    Type: Grant
    Filed: October 1, 2020
    Date of Patent: October 19, 2021
    Assignee: MOMI BRANDS, INC.
    Inventor: Carr Lane Quackenbush