Abstract: A fluid distribution system for delivering fluid internally of a body comprises a hollow needle and an implantable access port. The needle has a tip with a predetermined shape. The access port includes (a) a housing that includes at least two fluid outlets, (b) a septum received in the housing, and (c) a valve member rotatable in the housing. The valve member includes valve fluid inlet and outlet openings and a valve inlet passage extending from the inlet opening to the outlet opening. The valve inlet passage has a shape complementary to the shape of the needle tip. The valve member is rotatable into (i) a first position in which the valve fluid outlet opening communicates with a first housing fluid outlet and (ii) a second position in which the valve fluid outlet opening communicates with a second housing fluid outlet.

Abstract: A tube stabilising device (10, 20, 30) for a tube attached to a patient, comprising a base member (110, 210, 310) fixable to a surface, the base member having a support surface (112, 212, 312) for supporting the base member on a surface of the patient. The tube stabilising device further comprising a tube retaining member (120, 220, 320). The base member includes a cavity (114, 214, 314) configured to receive a flange (122, 222, 322) of the tube retaining member such that, when received, the cavity at least partially overlaps the flange so that the flange is retained by the base member, the tube retaining member is moveably attached to the base member and the flange is moveable within the cavity in any direction parallel to the support surface. The tube retaining member is configured to retain a tube extending from the patient such that, when retained, the tube is moveable relative to the base member.

Abstract: The present disclosure describes a syringe assembly including a syringe including a Luer connection and a tip, a plunger, a tip cap, a tamper evident cap disposed over the tip cap, and a film including a frangible connection. The film secures the tamper evident cap to the Luer connection, where the frangible connection can break under a force applied to the tamper evident cap such that the tamper evident cap disengages from the Luer connection when the frangible connection breaks.

Abstract: A fluid distribution system can include a water inlet configured to receive water from a supply spout. A supply line can be connected to the inlet, and an applicator tip can be connected to the supply line distal from the inlet. The applicator tip can be configured to spray water received through the supply line at the same time as the receiving of the water from the supply spout through the inlet. The system can further include a water pressurizing device that is operable to pressurize water received from the supply spout via the water inlet and supplied through the supply line to the applicator tip. The water pressurizing device can include one or more of a powered fluid pump and a source adapter. The system may include a fluid-actuated pressure clamp.

Abstract: A device for delivery of a medicament from a container (10) having an outlet (16) at a distal end of the container (10) and a stopper (22) for containing the medicament in the container (10).

Abstract: Needle assemblies for retractable needle syringes include a needle, a needle seal, and a needle retainer, wherein the needle includes one or more barbs substantially at its proximal end. The needle retainer engages an optional needle-over-mold component that is fixedly attached to the needle. The needle-over-mold may be connected to the distal surface of the needle seal and may travel, such as by being a couple component, with the needle during the operation of the syringe. A safety syringe includes a barrel having a needle assembly mounted at a distal end and a plunger assembly mounted at a proximal end. A drug may be contained in a drug chamber of barrel, between the plunger assembly and needle assembly, proximally of the needle seal for drug delivery to a user. The plunger assembly includes a plunger seal having a needle-engaging portion to capture the needle at the barb for retraction.

Abstract: A method of treating an anatomical cavity of a patient comprises introducing an infusion/aspiration catheter into the patient, such that a plurality of arms of the catheter reside within the anatomical cavity, delivering a fluid into the at least one of a connector, such that fluid exits the at least one fluid port of at least one of the arms, thereby infusing the anatomical cavity with the fluid, and aspirating the fluid into the at least one fluid port of at least one of the arms, such that the fluid exits the connector(s).

Abstract: An automatic injection device is provided, where the device includes a syringe carrier and a retraction assembly. The syringe carrier includes two identical parts that are discrete from one another and interlock with one another. The retraction assembly includes a shuttle and a follower, the follower having a moveable latch. The follower has a coupled configuration in which the latch is biasedly coupled to the shuttle, and a decoupled configuration in which the latch is in sliding engagement with a curvilinear surface of the shuttle.

Abstract: A cap assembly for a drug delivery device is described comprising a cap, and a clip element which is configured to be attached to the cap, the clip element comprising a first component, and a second component, wherein the first component is at least partly received by the second component, wherein the first component and the second component are firmly connected to one another, and wherein the connection between the first component and the second component is the means by which the second component is attached to the cap. Moreover, a method for assembling a cap assembly is described.

Abstract: A non-invasive interventional sheath securement device is used by clinicians for removably securing a sidearm of a vascular access sheath for the purpose of preventing the sheath's movement through or out of a puncture site during its deployment in an interventional medical procedure.

Abstract: A drug delivery device comprises a housing and a dose sleeve located within the housing, the dose sleeve being configured to move helically within the housing as a medicament dose is dialled into or delivered from the drug delivery device. A dose setting arrangement is coupled to the dose sleeve and is configured to cause helical movement of the dose sleeve as a medicament dose is dialled into the drug delivery device through rotation of a dose dial forming part of the dose setting component. A dose delivery arrangement comprising a dose button is coupled to the dose sleeve and is configured to cause delivery of medicament with helical movement of the dose sleeve and without rotation of the dose dial when the dose button is actuated. A first sensor arrangement is configured for detecting a rotation of the dose dial relative to the housing. A second sensor arrangement is configured for detecting movement of the dose sleeve relative to the housing.

Abstract: A sealed medication dispensing and administering device has a syringe, a plunger, a connecting holder, an elastic valve, and a liquid stopper. The syringe has an outer barrel having an air inlet tube and an inner barrel inserted inside the outer barrel and having a medication inlet tube. The plunger is inserted within the outer and inner barrels. The connecting holder is connected to the syringe and has a connecting cover with at least one outer connecting hole and two piercing needles respectively piercing inside the air inlet tube and the medication inlet tube. Inner spaces of the two piercing needles communicate with the at least one outer connecting hole. The elastic valve selectively covers the two piercing needles. The fluid stopper is disposed within the connecting cover and blocks one of the at least one outer connecting hole and the inner space of the air inlet tube.

Abstract: A medicament delivery device includes a case, a first plunger, a second plunger arranged telescopically with the first plunger, a first drive spring biasing the second plunger relative to the case, and a second drive spring biasing the first plunger relative to the second plunger.

Abstract: A control system for administration of a drug comprises a drug administration actuator for administering the drug to a patient at a controllable dosage; a monitor for measuring an effect of the drug on the patient; and a controller configured to determine a control signal to the drug administration actuator; wherein the controller is configured to implement a closed loop model-predictive control scheme comprising, for each of a series of time steps, minimizing a cost function subject to one or more constraints to determine the control signal, the cost function based at least in part on a reference level and the monitor measurement; wherein the control signal is used as an input to an auxiliary model to estimate at least one concentration level of the drug in the patient; and wherein the constraints comprise at least one constraint on the estimate of the concentration level of the drug.

Abstract: Disclosed herein is a fluid infusion device of the type that delivers medication fluid to the body of a patient. The device includes or cooperates with a fluid reservoir, and the device has a sealing assembly to receive and form a fluid seal with the fluid reservoir. A retractable sealing element surrounding a hollow fluid delivery needle may be used to seal a port of the fluid reservoir. The port may include a pressure vent that is sealed by the retractable sealing element. In one variation, the reservoir includes a moving valve sleeve that holds a septum. The septum moves to allow the reservoir to vent, and to form a seal with the port when the needle pierces the septum. In another variation, the device includes a needleless sealing assembly. In yet other variations, the device uses a needled fluid reservoir.

Abstract: Sensing systems, devices and methods are disclosed for determining the relative movement of first and second members of a medication delivery device which are proportional to the amount of a dose set and/or delivered by operation of the medication delivery device. A sensor is coupled with the first member. A pair of targets is coupled with the second member. Each target comprises an array of teeth which move through an area sensed by the sensor. The sensor thereby detects characteristic values of a sensed parameter corresponding to the combined relative positions of the first and second members. The sensing system outputs this information to a processor which determines the amount of the dose set and/or delivered. Related medication delivery devices and methods are also disclosed.

Abstract: A fat-harvesting syringe having a multi-functional plunger assembly. The plunger assembly comprises an outer plunger rod body, an inner central plunger rod and a piston seal assembly. The outer plunger rod body having a first and a second end. The first end having a central lumen all at its finger grip handle and at the second end having flanges that are expandable. Once the central plunger inner rod is inserted fully into central lumen of plunger rod body, the expandable flanges expands and engages with the piston seal assembly. Also when the inner plunger rod is retracted, the plunger body flanges retract back and disengages from piston seal assembly.

Abstract: An electrical information device and a medicament delivery device are presented. The electrical information device includes at least one start of delivery sensor configured to detect a distal axial movement of a release member of the medicament delivery device. The release member is configured to be distally moved when an activator member of the medicament delivery device 1 is forced distally. The electrical information device also includes at least one information communication unit, which is configured to communicate information related to the medicament delivery. The electrical information device further includes at least one activation unit, which is configured to activate the at least one information communication unit based on a detected distal axial movement of the release member.

Abstract: A transdermal drug delivery apparatus includes a receptacle having a housing and a microneedle assembly mounted to the housing. The apparatus includes a reservoir for being mounted to the receptacle. The reservoir has an interior for containing fluid for being supplied to the microneedle assembly. The apparatus is adapted so that, when the apparatus is assembled, the reservoir is configured to move relative to the microneedle assembly along a path from an outer position to an inner position. The reservoir is closer to the microneedle assembly in the inner position than in the outer position. In the outer position, the reservoir is out of fluid communication with the microneedle assembly, and in the inner position, the reservoir is in fluid communication with the microneedle assembly. The apparatus also includes a plurality of connector parts spaced apart from one another along the path.

Abstract: Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.