Patents Examined by Robert J Eom
  • Patent number: 11795490
    Abstract: Disclosed are apparatus, method and system for monitoring mold based on weak electrical signals. The apparatus comprises a mold collector, a power supply, a trans-impedance amplifier, and an analog-to-digital converter, wherein the mold collector is smeared with a trophoplasm, and a substrate of the mold collector has electrical conductivity, the power supply is used for applying a voltage to the substrate of the mold collector, the trans-impedance amplifier is used for amplifying a weak current generated from the substrate of the mold collector to a voltage signal, and the analog-to-digital converter is used for converting the voltage signal amplified by the trans-impedance amplifier into a digital signal for determining the quantity of molds.
    Type: Grant
    Filed: June 10, 2021
    Date of Patent: October 24, 2023
    Assignee: GUANGZHOU UNIVERSITY
    Inventors: Zhaosong Fang, Zhangyi Xie, Zhimin Zheng, Tao Wen
  • Patent number: 11788998
    Abstract: The ethylene sensor is formed from a substrate with a gold thin film layer formed thereon. The substrate may be formed from soda-lime glass with a thickness of approximately 1.0 mm. Correspondingly, the gold layer may have a thickness of approximately 200 nm. The gold layer is divided into first and second regions or electrodes by a variable impedance channel containing K0.003Au0.008Mg0.009Ca0.015Si0.11Na0.175O0.68 as an ethylene selective material. The channel may be configured such that first and second sets of interdigitated gold fingers are defined in the first and second regions or electrodes, respectively. An ohmmeter is connected to the first and second regions to measure a resistance therebetween. A reference resistance is initially measured that is indicative of an absence of ethylene. Subsequent measurements of the resistance are compared against this reference resistance, with variations in the measured resistance indicating the presence of ethylene.
    Type: Grant
    Filed: January 20, 2023
    Date of Patent: October 17, 2023
    Assignee: KING FAISAL UNIVERSITY
    Inventor: Nagih Mohammed Shaalan
  • Patent number: 11782019
    Abstract: A sensor component includes a sensor including a sensor surface and a reaction site in cooperation with the sensor and exposing the sensor surface. The reaction site including a reaction site surface. A surface agent is bound to the reaction site surface or the sensor surface. The surface agent includes a surface active functional group reactive with Bronsted base or Lewis acid functionality on the reaction site surface or the sensor surface and including distal functionality that does not have a donor electron pair.
    Type: Grant
    Filed: October 1, 2020
    Date of Patent: October 10, 2023
    Assignee: Life Technologies Corporation
    Inventors: Ronald L. Cicero, Marc Glazer, Yufang Wang, Christina E Inman, Jeremy Gray, Joseph Koscinski, James A. Ball, Phil Waggoner, Alexander Mastroianni
  • Patent number: 11761921
    Abstract: Disclosed herein are compositions for permeable outer diffusion control membranes for creatinine and creatine sensors and methods of making such membranes.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: September 19, 2023
    Assignee: INSTRUMENTATION LABORATORY COMPANY
    Inventor: Xiaoxian Xu
  • Patent number: 11761916
    Abstract: A method for manufacturing a gas sensor may be provided, the method comprising the steps of: preparing a metal nanowire; manufacturing a thermoelectric composite by adding a polymer bead to the metal nanowire, and then mechanically mixing same; manufacturing a thermoelectric layer by hot-pressing the thermoelectric composite; forming a first electrode on the upper surface of the thermoelectric layer, and forming a second electrode on the lower surface of the thermoelectric layer; and disposing a heating catalyst layer on the first electrode.
    Type: Grant
    Filed: August 12, 2019
    Date of Patent: September 19, 2023
    Assignee: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS
    Inventors: Yong Ho Choa, Seil Kim, Yoseb Song
  • Patent number: 11761076
    Abstract: A microfluidic device for use with a microfluidic delivery system, such as an organic vapor jet printing device, includes a glass layer that is directly bonded to a microfabricated die and a metal plate via a double anodic bond. The double anodic bond is formed by forming a first anodic bond at an interface of the microfabricated die and the glass layer, and forming a second anodic bond at an interface of the metal plate and the glass layer, where the second anodic bond is formed using a voltage that is lower than the voltage used to form the first anodic bond. The second anodic bond is formed with the polarity of the voltage reversed with respect to the glass layer and the formation of the first anodic bond. The metal plate includes attachment features that allow removal of the microfluidic device from a fixture.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: September 19, 2023
    Assignee: The Regents of the University of Michigan
    Inventors: Stephen Forrest, Gregory McGraw, Siddharth Harikrishna Mohan, Diane L. Peters
  • Patent number: 11739164
    Abstract: Provided are compositions that include at least one two-dimensional layer of an inorganic compound and at least one layer of an organic compound in the form of one or more polypeptides. Methods of making and using the materials are provided. The organic layer contains one or more polypeptides, each of which have alternating repeats of crystallite-forming subsequences and amorphous subsequences. The crystallite-forming subsequences form crystallites comprising stacks of one or more beta-sheets. The amorphous subsequences form a network of hydrogen bonds. A method includes i) combining one or more polypeptides with an inorganic material and an organic solvent, and ii) depositing one or more polypeptides, the inorganic material and the organic solvent onto a substrate. These steps can be repeated to provide a composite material that is a multilayer composite material. The composite materials can be used in a wide array of textile, electronic, semi-conducting, and other applications.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: August 29, 2023
    Assignee: The Penn State Research Foundation
    Inventors: Melik Demirel, Mert Vural, Mauricio Terrones, Yu Lei, Ibrahim Tarik Ozbolat
  • Patent number: 11738346
    Abstract: Methods and apparatus to mitigate bubble formation in a liquid are disclosed. An example apparatus disclosed herein includes a bottom wall, a first baffle cantilevered from the bottom wall, and a second baffle cantilevered from the bottom wall. The first baffle is spaced apart from the second baffle, and the first baffle and the second baffle are positioned radially relative to an axis of rotation of the apparatus.
    Type: Grant
    Filed: February 19, 2021
    Date of Patent: August 29, 2023
    Assignee: ABBOTT LABORATORIES
    Inventors: Robert Paul Luoma, II, Brian L. Ochranek, Cheryl L. Davidson, Bradley C. Weston
  • Patent number: 11740229
    Abstract: A method for deriving a calibration curve for determining a concentration of an analyte in an electrochemical reactor comprises determining a current level between a functionalized electrode and a reference electrode in the electrochemical reactor in absence of an analyte, the current level forming a zero-concentration current; injecting a fluid comprising an analyte in a first given concentration in the electrochemical reactor, determining after the predetermined amount of time a first calibration current level corresponding to the first given concentration and calculating a first current ratio of the first current level to the zero-concentration current; repeating the previous step for at least a second given concentration of the analyte, yielding at least a second current ratio of a second current level to the zero-concentration current; obtaining a calibration curve indicative of current ratio as a function of concentration from the first current ratio and at least the second current ratio.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: August 29, 2023
    Assignees: UNIVERSITEIT GENT, IMEC VZW
    Inventors: Jan Vanfleteren, Patricia Khashayar
  • Patent number: 11733240
    Abstract: A sensor apparatus capable of measuring an analyte with excellent sensitivity is provided. A sensor apparatus includes an element substrate; a detecting section disposed on an upper surface of the element substrate, the detecting element including a reaction section having an immobilization film to detect an analyte, a first IDT electrode configured to generate an acoustic wave which propagates toward the reaction section, and a second IDT electrode configured to receive the acoustic wave which has passed through the reaction section; and a protective film which covers the first IDT electrode and the second IDT electrode. The element substrate is configured so that a region where the reaction section is located is at a lower level than a region where the first IDT electrode is located and a region where the second IDT electrode is located.
    Type: Grant
    Filed: June 18, 2020
    Date of Patent: August 22, 2023
    Assignee: KYOCERA CORPORATION
    Inventor: Kyohei Kobayashi
  • Patent number: 11717195
    Abstract: The present invention relates to systems and methods for assessing brain health and detecting neurological conditions. The invention more particularly relates to systems and methods for diagnosing neurological conditions and analyzing rain health from analysis of a biological fluid sample, such as a saliva sample, that looks for and determines the significance of peripheral markers of blood-brain barrier disruption. The present invention further provides a diagnostic system and method with a higher negative predictive value of brain injury than currently known tests are able to provide, so as to reduce the need for computerized tomography or magnetic resonance imaging scans to affirmatively determine that brain or cerebrovascular injury has not occurred, and thus to improve suspected brain injury patient health care while reducing the expense of such care.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: August 8, 2023
    Assignee: FloTBI Inc.
    Inventors: Damir Janigro, Aaron Dadas, Edward J. Rapp
  • Patent number: 11714075
    Abstract: A chemical sensor and a system and method for sensing a chemical species. The chemical sensor includes a plurality of nanofibers whose electrical impedance varies upon exposure to the chemical species, a substrate supporting and electrically isolating the fibers, a set of electrodes connected to the plurality of fibers at spatially separated points to permit the electrical impedance of the plurality of fibers to be measured, and a membrane encasing the fibers and having a thickness ranging from 50 ?m to 5.0 mm. The system includes the chemical sensor, an impedance measuring device coupled to the electrodes and configured to determine an electrical impedance of the plurality of fibers, and an analyzer configured to identify the chemical species based on a change in the electrical impedance.
    Type: Grant
    Filed: September 25, 2020
    Date of Patent: August 1, 2023
    Assignee: Research Triangle Institute
    Inventors: David S. Ensor, Li Han
  • Patent number: 11701653
    Abstract: A microfluidic apparatus is provided that includes a thermoelectrically-activated pixel array, a microfluidic chip, and control circuitry. The pixel array may include a plurality of thermal pixels, with each thermal pixel including a thermoelectric device. The microfluidic chip may include a microfluidic channel disposed adjacent to the thermal pixels such that thermal energy generated by the thermal pixels is received by the microfluidic channel to form a localized spot within the microfluidic channel corresponding to each thermal pixel. The control circuitry may be electrically coupled to each of the thermal pixels and configured to control the thermal energy being generated by each thermal pixel to control a temperature at each localized spot within the microfluidic channel.
    Type: Grant
    Filed: October 17, 2018
    Date of Patent: July 18, 2023
    Assignee: The Johns Hopkins University
    Inventors: Konstantinos Gerasopoulos, Rama Venkatasubramanian, Mekbib Astatke
  • Patent number: 11674916
    Abstract: A gas sensing device comprising a substrate comprising an etched cavity portion and a substrate portion, a dielectric layer disposed on the substrate, wherein the dielectric layer comprises a dielectric membrane, wherein the dielectric membrane is adjacent to the etched cavity portion of the substrate, a heater located within the dielectric layer; a material for sensing a gas; and one or more polysilicon electrodes coupled with the material for sensing a gas.
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: June 13, 2023
    Assignee: Sciosense B.V.
    Inventors: Florin Udrea, Syed Zeeshan Ali
  • Patent number: 11662329
    Abstract: Disclosed herein are compositions for permeable outer diffusion control membranes for creatinine and creatine sensors and methods of making such membranes.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: May 30, 2023
    Assignee: INSTRUMENTATION LABORATORY COMPANY
    Inventor: Xiaoxian Xu
  • Patent number: 11662337
    Abstract: This productivity evaluation method is for evaluating productivity of a chemical substance in a process comprising a first step of obtaining gas from a waste material and a second step of synthesizing a chemical substance from the gas obtained in the first step in the presence of a catalyst, said method including: a first carbon mass calculation stage of calculating mass of carbon contained in the waste material, a second carbon mass calculation stage of calculating mass of carbon contained in the chemical substance produced in said process, and a productivity evaluation stage of evaluating the productivity of the chemical substance based on values of the mass of carbon which are calculated in the first carbon mass calculation stage and the second carbon mass calculation stage.
    Type: Grant
    Filed: May 4, 2020
    Date of Patent: May 30, 2023
    Assignee: SEKISUI CHEMICAL CO., LTD.
    Inventors: Yoji Fujimori, Akio Shokaku
  • Patent number: 11650192
    Abstract: A device for measuring the total organic carbon content (TOC) of a sample fluid comprises a measuring cell (2) defining a volume (3) for containing a sample fluid and an excimer lamp (20) arranged to cause an oxidation reaction of the sample fluid by emitting radiation onto the sample fluid in the volume (3). A pair of electrodes is arranged to measure the conductivity of the sample fluid during the oxidation reaction and at least one temperature senor (31) is arranged on the measuring cell (2) to measure a temperature that is related to the sample fluid. The total organic carbon content (TOC) of the sample fluid is determined on the basis of the measured conductivity compensated by the temperature related to the sample fluid.
    Type: Grant
    Filed: February 20, 2018
    Date of Patent: May 16, 2023
    Inventors: Pascal Rajagopalan, Julien Gross, Pierre Caruso
  • Patent number: 11630094
    Abstract: Described is an oxygen permeable layer for detection of molecular oxygen, wherein the layer has a carrier material in which at least one particle is comprised, wherein the carrier material is polyvinylidene fluoride or a copolymer of polyvinylidene fluoride, and the particle comprises a polymer or a copolymer, wherein the polymer or copolymer of the particle has a chemically covalently bonded indicator compound for detection of molecular oxygen. In addition, a multilayer system for detection of molecular oxygen is described. Also described are a method for producing the layer, and the use of the layer or of the multilayer system for detection of molecular oxygen.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: April 18, 2023
    Assignee: Hamilton Bonaduz AG
    Inventors: Claudius-Michael Ortega Schulte, Dirk Schönfuss, {hacek over (S)}pela Willi, Sara Simonato
  • Patent number: 11609223
    Abstract: A device for analysis of cells comprises: an active sensor area (104) presenting a surface for cell growth; a microelectrode array (102) comprising a plurality of pixels (110) in the active sensor area (104), wherein each pixel (110) comprises at least one electrode (120) at the surface, wherein each pixel (110) is configured to control the configuration of the pixel circuitry and set a measurement modality of the pixel; recording circuitry having a plurality of recording channels (130), wherein each pixel (110) is connected to a recording channel (130), wherein each recording channel (130) comprises a reconfigurable component (131), which is selectively controlled between being set to a first mode, in which the reconfigurable component (131) is configured to amplify a received pixel signal, and being set to a second mode, in which the reconfigurable component (131) is configured to selectively pass a frequency band of the received pixel signal.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: March 21, 2023
    Assignee: IMEC VZW
    Inventor: Carolina Mora Lopez
  • Patent number: 11596704
    Abstract: The present disclosure relates to an article for detecting a disinfectant via visual feedback. The article have a first substrate with a first major surface and opposite ends. The article also comprises a process indicator disposed on at least a portion of the first major surface. The process indicator reacts with at least one liquid disinfectant selected from the group consisting of glutaraldehyde, ortho-phthalaldehyde, hydrogen peroxide, peroxyacetic acid, and combinations thereof. The process indicator can be formed from a synthetic amine-containing polymer derived from polyethylenimine (PEI). The article can have a flow channel that is formed by a portion of the process indicator and that extends between the opposite ends. The disclosure also relates to a kit containing the article as well as a method of using the article in a disinfection process. The article is used to diagnose issues in an automated endoscope reprocessors (AERs).
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: March 7, 2023
    Assignee: 3M Innovative Properties Company
    Inventors: Timothy J. Nies, G. Marco Bommarito, Christopher J. Claypool