Patents Examined by Robert V. Hines
  • 1-Aryl-4-amino-cyclohexan-1-ols
    Patent number: 4288623
    Abstract: Sprio[cyclohexane-1,1'(3'H)-isobenzofuran]s are useful as anti-depressants, tranquilizers, analgesics and anticonvulsants.
    Type: Grant
    Filed: November 28, 1980
    Date of Patent: September 8, 1981
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Lawrence L. Martin, Manfred Worm
  • Dinitriles, diamines, and polyamides
    Patent number: 4288625
    Abstract: Unsaturated dinitriles are reacted with an aromatic compound such as benzene in the presence of a Lewis acid such as aluminum chloride to yield novel aralkylenedinitriles, such as 5-methyl-5-phenylnonanedinitrile and isomers thereof. The aralkylenedinitriles can be reduced to novel aralkylenediamines or novel cycloalkylalkylenediamines. Polymerization of the aralkylenediamines or cycloalkylalkylenediamines with polycarboxylic acids provides novel polyamides of tough, clear, colorless character.
    Type: Grant
    Filed: August 23, 1976
    Date of Patent: September 8, 1981
    Assignee: Phillips Petroleum Co.
    Inventors: Charles A. Drake, Stanley D. Turk
  • Molybdenum catalyst for aniline-formaldehyde condensation
    Patent number: 4287364
    Abstract: Covers a method of preparing diaminodiphenylmethanes and higher homologues thereof which comprises the step of condensing aniline and formaldehyde in the presence of a molybdenum aluminide catalyst.
    Type: Grant
    Filed: September 24, 1980
    Date of Patent: September 1, 1981
    Assignee: Texaco Inc.
    Inventors: Edward T. Marquis, Robert M. Gipson, Lewis W. Watts, Jr.
  • 2-Aryl-1,2-dialkylcycloalkylamines
    Patent number: 4287212
    Abstract: Novel 2-aryl-1,2-dialkylcycloalkylamines, physiologically tolerable acid addition salts thereof, and a method of preparing the same are described. These compounds are useful as analgesic and diuretic agents.
    Type: Grant
    Filed: February 27, 1978
    Date of Patent: September 1, 1981
    Assignee: American Hoechst Corporation
    Inventors: Grover C. Helsley, Horst Dornauer, Larry Davis
  • Silver catalysts used to prepare polyaminopolyphenylmethanes
    Patent number: 4286107
    Abstract: Covers a method of preparing diaminodiphenylmethanes and higher homologues thereof which comprises the step of condensing aniline and formaldehyde in the presence of a silver tungstate catalyst.
    Type: Grant
    Filed: October 2, 1980
    Date of Patent: August 25, 1981
    Assignee: Texaco Inc.
    Inventors: Edward T. Marquis, Lewis W. Watts, Jr.
  • Tungsten catalyzed aniline-formaldehyde condensation
    Patent number: 4284815
    Abstract: Covers a method of preparing diaminodiphenylmethanes and higher homologues thereof which comprises the step of condensing aniline and formaldehyde in the presence of a tungsten boride or sulfide catalyst.
    Type: Grant
    Filed: September 22, 1980
    Date of Patent: August 18, 1981
    Assignee: Texaco Inc.
    Inventors: Edward T. Marquis, Lewis W. Watts, Jr., Robert M. Gipson
  • Method of preparing polyaminopolyphenylmethanes
    Patent number: 4284816
    Abstract: Covers a method of preparing diaminodiphenylmethanes and higher homologues thereof which comprises the step of condensing aniline and formaldehyde in the presence of a tungsten silicide catalyst.
    Type: Grant
    Filed: September 17, 1980
    Date of Patent: August 18, 1981
    Assignee: Texaco Inc.
    Inventors: Edward T. Marquis, Lewis W. Watts, Jr.
  • 2-Decarboxy-2-aminomethyl-19-hydroxy-PG compounds
    Patent number: 4283558
    Abstract: The present invention provides novel 2-decarboxy-2-hydroxymethyl-19,20-didehydro-13,14-dihydro-PG.sub.1 compounds methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.
    Type: Grant
    Filed: October 26, 1979
    Date of Patent: August 11, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • Trans-n-cinnamyl-n-methyl-(1-naphthylmethyl)amine
    Patent number: 4282251
    Abstract: Cinnamylalkyl-1-naphthylmethylamines, useful as antimycotic agents, and processes for their production.
    Type: Grant
    Filed: December 3, 1979
    Date of Patent: August 4, 1981
    Assignee: Sandoz Ltd.
    Inventor: Daniel Berney
  • Reductive alkylation and dehalogenation of m-nitrobenzyl halides
    Patent number: 4282380
    Abstract: Substituted N-alkylated aromatic amines are produced by reductively alkylating and dehalogenating the corresponding m-nitrobenzyl halides with pressurized hydrogen in the presence of a ketone and a platinum catalyst.
    Type: Grant
    Filed: July 5, 1979
    Date of Patent: August 4, 1981
    Assignee: American Cyanamid Company
    Inventor: Albert W. Lutz
  • Bis-(2-benzylaminoethyl)-disulfides
    Patent number: 4273940
    Abstract: It has been found that bis(2-benzylaminoethyl)-disulfides with the phenyl rings carrying various simple substituents, are highly effective anti-inflammatories and inhibit chemotaxis of human neutrophils.
    Type: Grant
    Filed: May 13, 1980
    Date of Patent: June 16, 1981
    Assignee: Abbott Laboratories
    Inventors: Fortuna Haviv, George W. Carter
  • Phenyl-cyclohexadiene-alkylamine derivatives
    Patent number: 4269788
    Abstract: Cyclohexadiene derivatives of the formula ##STR1## wherein R.sup.1,R.sup.2,R.sup.3 and R.sup.4 are as hereinafter set forth, are described. The compounds of formula I are useful as analgesic agents.
    Type: Grant
    Filed: October 4, 1979
    Date of Patent: May 26, 1981
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Peter M. Muller, Rudolf Pfister, Rene Urban
  • Hydrocarbon dehydrogenation with a nonacidic multimetallic catalytic composite
    Patent number: 4268707
    Abstract: Dehydrogenatable hydrocarbons are dehydrogenated by contacting them, at dehydrogenation conditions, with a nonacidic catalytic composite comprising a combination of catalytically effective amounts of a platinum group component, a cobalt component, a lanthanide series component and an alkali or alkaline earth component with a porous carrier material in amounts sufficient to result in a composite containing about 0.01 to about 2 wt. % platinum group metal, about 0.05 to about 5 wt. % cobalt, about 0.01 to about 5 wt. % lanthanide series metal and about 0.1 to about 5 wt. % alkali metal or alkaline earth metal.
    Type: Grant
    Filed: May 9, 1980
    Date of Patent: May 19, 1981
    Assignee: UOP Inc.
    Inventor: George J. Antos
  • N-substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto
    Patent number: 4267193
    Abstract: N-substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto, useful as antihypertensive agents, are prepared by reaction of an N-substituted aniline with a polyfluoroacetone.
    Type: Grant
    Filed: May 4, 1979
    Date of Patent: May 12, 1981
    Assignee: Schering Corporation
    Inventors: Bernard R. Neustadt, Elijah H. Gold
  • 5,6,7,8-Tetrahydronaphthalene hypotensive agents
    Patent number: 4267373
    Abstract: 5,6,7,8-Tetrahydronaphthalenes having the structure ##STR1## and the pharmaceutically acceptable salts thereof, are useful as blood pressure lowering agents. In the above formula R.sub.1 can be hydrogen or alkyl; R.sub.2 is alkyl; R.sub.3 and R.sub.4 can each be hydrogen, hydroxyl, alkoxy, or arylalkoxy, but both cannot be hydroxyl. Those compounds wherein at least one of R.sub.3 and R.sub.4 is other than hydrogen are novel, and constitute a part of this invention.
    Type: Grant
    Filed: November 14, 1977
    Date of Patent: May 12, 1981
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Frederic P. Hauck, Christopher M. Cimarusti, Joseph E. Sundeen
  • Insecticidal hydroxylamine ethers
    Patent number: 4265907
    Abstract: Insecticidal compounds having the formula: ##STR1## wherein R is halogen (Cl, F, Br), C.sub.1 -C.sub.4 alkyl, NO.sub.2, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, cyano, CF.sub.3, CF.sub.3 O, CF.sub.3 S, ClF.sub.2, CHF.sub.2 O, or CHF.sub.2 S; n is 0, 1, or 2; R.sub.1 is C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.6 cycloalkyl, or C.sub.2 -C.sub.4 alkenyl; and R.sup.2 is hydrogen, cyano, formyl, C.sub.1 -C.sub.4 acyl, C.sub.1 -C.sub.4 carboalkoxy, carbamoyl, N-C.sub.1 -C.sub.4 alkylcarbamoyl, or N,N-di C.sub.1 -C.sub.4 alkylcarbamoyl.
    Type: Grant
    Filed: December 31, 1979
    Date of Patent: May 5, 1981
    Assignee: Mobil Oil Corporation
    Inventor: Jill H. Paul
  • Production of secondary amines
    Patent number: 4264776
    Abstract: Tertiary amines such as alkyl or benzyl amines are catalytically oxidized by oxygen over an activated carbon catalyst to selectively produce secondary amines.
    Type: Grant
    Filed: January 2, 1976
    Date of Patent: April 28, 1981
    Assignee: Monsanto Company
    Inventors: Arnold Hershman, Donald J. Bauer
  • Synthesis of .beta.-aminostyrenes
    Patent number: 4264775
    Abstract: A simple process for the preparation of .beta.-aminostyrenes proceeds from anilines by successively diazotizing, reacting with a vinyl ester, and reacting with a secondary amine without purification of the intermediate products. The compounds are reactive enamines useful in organic synthesis.
    Type: Grant
    Filed: October 27, 1976
    Date of Patent: April 28, 1981
    Assignee: Eli Lilly and Company
    Inventor: William A. White
  • Process of preparing styrenated diphenylamine
    Patent number: 4263456
    Abstract: Styrenated diphenylamine is prepared by reacting styrene with diphenylamine in the presence of undried acidic clay catalyst.
    Type: Grant
    Filed: December 2, 1976
    Date of Patent: April 21, 1981
    Assignee: The Goodyear Tire & Rubber Company
    Inventor: Edward A. Rogers, Jr.
  • Lubricant composition containing alkali metal borate and stabilizing oil-soluble acid
    Patent number: 4263155
    Abstract: Disclosed is a lubricant composition containing an oil of lubricating viscosity having dispersed therein a particulate hydrated alkali metal borate and an effective amount oil soluble acid which stabilizes the composition against the adverse effects of water contamination.
    Type: Grant
    Filed: January 7, 1980
    Date of Patent: April 21, 1981
    Assignee: Chevron Research Company
    Inventor: Kenneth Frost