Patents Examined by Robert V. Hines
  • Patent number: 4216231
    Abstract: 9,10-Dihydro-9,10-methanoanthracene N-oxide derivatives represented by the formula: ##STR1## wherein A represents a straight or branched C.sub.1 -C.sub.6 alkylene; R.sup.1 and R.sup.2 each represents C.sub.1 -C.sub.4 alkyl or phenyl-C.sub.1 -C.sub.4 alkyl, or ##STR2## represents the group ##STR3## and X represents methylene, hydroxymethylene, C.sub.1 -C.sub.4 alkyl ##STR4## or hydroxy-C.sub.1 -C.sub.4 alkyl ##STR5## and their pharmaceutically acceptable acid addition salts which are useful as anti-depressants, tranquilizers, or anti-epileptics.
    Type: Grant
    Filed: January 30, 1979
    Date of Patent: August 5, 1980
    Assignee: Shionogi & Co., Ltd.
    Inventors: Hiroshi Tanida, Tadashi Irie
  • Patent number: 4215146
    Abstract: Novel amine and amidine derivatives of di-0-(n-higher alkyl and alkenyl)-glycerols and -propanediols, and their pharmaceutically acceptable acid addition salts, are useful for combating viral infections in mammals. Of particular interest is 1,3-di-0-(n-hexadecyl)-2-0-(3-aminopropyl)-glycerol, and its pharmaceutically acceptable acid addition salts.
    Type: Grant
    Filed: February 15, 1979
    Date of Patent: July 29, 1980
    Assignee: Pfizer Inc.
    Inventor: Allen R. Kraska
  • Patent number: 4214082
    Abstract: Dyestuffs of the formula ##STR1## wherein S, m, X, R.sub.1, R.sub.2, R.sub.3, R.sub.4 and n have the meaning indicated in the description, and their use for dyeing and printing textile materials containing hydroxyl groups and textile materials containing nitrogen, in particular textile materials of natural and regenerated cellulose, and furthermore of wool, silk and synthetic polyamide and polyurethane fibres. The resulting dyeings are distinguished by good fastness to light and wet processing.
    Type: Grant
    Filed: April 20, 1979
    Date of Patent: July 22, 1980
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Harms, Klaus Wunderlich, Klaus von Oertzen
  • Patent number: 4212822
    Abstract: In the preparation of an o-dialkylaminomethylphenol of the formula ##STR1## in which R.sup.1 and R.sup.2 each independently is alkyl with 1 to 6 carbon atoms, or R.sup.1 and R.sup.2 conjointly with the adjacent nitrogen atom, form a five-membered or six-membered ring, by reacting phenol, formaldehyde or paraformaldehyde and an amine of the formula ##STR2## the improvement which comprises carrying out the reaction in the presence of an organic liquid which is immiscible with water but which is a solvent for the phenol and amine employed as starting materials and the o-dialkylaminomethylphenol which is formed.
    Type: Grant
    Filed: December 30, 1976
    Date of Patent: July 15, 1980
    Assignee: Bayer Aktiengesellschaft
    Inventor: Hermann Arold
  • Patent number: 4212821
    Abstract: Covers a method of preparing diaminodiphenylmethanes and higher homologues thereof which comprises the step of condensing aniline and formaldehyde in the presence of hydroxy ethane sulfonic acid catalyst.
    Type: Grant
    Filed: February 16, 1979
    Date of Patent: July 15, 1980
    Assignee: Texaco Development Corporation
    Inventors: Edward T. Marquis, Walter H. Brader, Jr.
  • Patent number: 4210601
    Abstract: Aryl[4,4'-bis(di-loweralkylamino)benzhydryl]-sulfones are prepared by reacting a 4-di(loweralkylamino)benzaldehyde with a di(loweralkyl)aniline and an aryl sulfinate.
    Type: Grant
    Filed: January 22, 1979
    Date of Patent: July 1, 1980
    Assignee: American Cyanamid Company
    Inventors: John P. Dundon, Erwin Klingsberg, John H. Bright
  • Patent number: 4210424
    Abstract: Oil-soluble combinations of (A) ethylene polymer or copolymer, (B) normal paraffinic wax composed of normal hydrocarbons whose average molecular weight is within the range of from 300 to 650, and (C) nitrogen compounds, such as amides, amine salts and ammonium salts, of carboxylic acids or anhydrides, are useful in improving the cold flow properties of distillate hydrocarbon fuel oils. Preferably, the wax contains n-paraffins ranging from C.sub.23 to C.sub.37 inclusive. If desired, the combination can be usefully stabilized by the addition of one or more compatibility additives, i.e. a polymer having alkyl side chains of 6 to 30 carbon atoms and derived from carboxylic acid esters and/or olefins or C.sub.8 -C.sub.18 alkanol, e.g. tridecyl alcohol or mixtures of said polymer and alkanol.
    Type: Grant
    Filed: November 3, 1978
    Date of Patent: July 1, 1980
    Assignee: Exxon Research & Engineering Co.
    Inventors: Nicholas Feldman, Jack Ryer, Martin F. Dooley
  • Patent number: 4209468
    Abstract: Oligomeric or polymeric triaryl- and substituted triarylphosphine compounds which are non-digestible and non-absorbable by animals are disclosed. These compounds act as antioxidants by inhibiting the buildup of hydroperoxides of unsaturated fatty acids, e.g., in foods.
    Type: Grant
    Filed: February 21, 1978
    Date of Patent: June 24, 1980
    Assignee: The Procter & Gamble Company
    Inventor: Joel I. Shulman
  • Patent number: 4208349
    Abstract: Process for the production of 2-[N-(2-hydroxyethyl)-N-lower alkylaminomethyl]benzhydrols by reducing N-(2-haloethyl)-N-lower alkyl-o-benzoylbenzamides in an inert solvent with sodium borohydride in the presence of an alkanoic acid.
    Type: Grant
    Filed: March 5, 1979
    Date of Patent: June 17, 1980
    Assignee: Riker Laboratories, Inc.
    Inventor: Peter G. Watson
  • Patent number: 4207077
    Abstract: Pure methyl-t-butyl ether is used as a cosolvent for hydrous ethanol in gasoline fuel mixtures. The ether solubilizes grain alcohol in all proportions in low aromatics content gasolines.
    Type: Grant
    Filed: February 23, 1979
    Date of Patent: June 10, 1980
    Assignee: Texaco Inc.
    Inventors: Francis S. Bove, William M. Sweeney, Sheldon Herbstman
  • Patent number: 4207076
    Abstract: Crude ethyl-t-butyl ether is used as a cosolvent for hydrous ethanol in gasoline fuel mixtures. The ether solubilizes grain alcohol in all proportions in low aromatic content gasolines.
    Type: Grant
    Filed: February 23, 1979
    Date of Patent: June 10, 1980
    Assignee: Texaco Inc.
    Inventors: Francis S. Bove, Sheldon Herbstman
  • Patent number: 4207343
    Abstract: 1-Phenyl-3-(optionally substituted phenoxy)-propylamines, inhibitors of norepinephrine uptake.
    Type: Grant
    Filed: June 22, 1978
    Date of Patent: June 10, 1980
    Assignee: Eli Lilly and Company
    Inventors: Edward R. Lavagnino, Lawrence J. McShane, Bryan B. Molloy
  • Patent number: 4206145
    Abstract: Certain substituted aralkylanilines in which the aromatic aniline ring carries, at the para position to the amino function, a substituent which comprises a carboxylic acid, salt or ester, an alkyl, hydroxyalkyl, cyano or acyl group, have hypolipidaemic activity.
    Type: Grant
    Filed: December 12, 1977
    Date of Patent: June 3, 1980
    Assignee: Beecham Group Limited
    Inventors: Richard M. Hindley, Keith H. Baggaley
  • Patent number: 4206146
    Abstract: The present specification relates to novel 9-deoxy-9-methylene-trans-2,3-didehydro-PGF compounds with improved pharmacological properties. While these compounds are useful in inducing a wide variety of prostaglandin-like pharmacological effects, they are specifically useful as regulators of procreation and fertility.
    Type: Grant
    Filed: August 11, 1978
    Date of Patent: June 3, 1980
    Assignee: The Upjohn Company
    Inventor: Gordon L. Bundy
  • Patent number: 4203922
    Abstract: This invention relates to a novel aromatic diamine and more particularly to the use of said diamine for the preparation of thermally stable high-molecular weight polymers including, for example, polyamides, polyamideimides, polyimides, and the like. This diamine is obtained by reacting a stoichometric amount of a disodium salt of 2,2-bis(4-hydroxyphenyl) hexafluoropropane with 4-chloronitrobenzene to obtain an intermediate, 2,2-bis[4-(4-nitrophenoxy)phenyl] hexafluoropropane, which is reduced to the corresponding 2,2-bis[4-(4-aminophenoxy)phenyl] hexafluoropropane.
    Type: Grant
    Filed: October 11, 1977
    Date of Patent: May 20, 1980
    Assignee: TRW Inc.
    Inventors: Robert J. Jones, Michael K. O'Rell, Jim M. Hom
  • Patent number: 4202839
    Abstract: N-Amino substituted aniline and 1,3-phenylenediamine compounds having 1 or 2 nitro groups on the aromatic ring. The compounds are useful as herbicides and as intermediates for preparing herbicides.
    Type: Grant
    Filed: December 26, 1978
    Date of Patent: May 13, 1980
    Assignee: United States Borax & Chemical Corporation
    Inventors: Don L. Hunter, William G. Woods, James D. Stone, Cecil W. LeFevre
  • Patent number: 4202904
    Abstract: New chemicals containing two diphenylaminomethane groups, linked together by a moiety other than oxygen, e.g., 1,2-bis[4-(3-methyl-alpha-amino-benzyl)phenoxy]ethane, are effective antimicrobial agents useful as agricultural or industrial fungicides and bactericides.
    Type: Grant
    Filed: October 24, 1978
    Date of Patent: May 13, 1980
    Assignees: Uniroyal, Inc., Uniroyal Ltd.
    Inventors: Bogislav von Schmeling, Walter R. Boos
  • Patent number: 4201790
    Abstract: Benzophenone derivatives of the formula: ##STR1## wherein R.sup.1 is isopropyl, t-butyl or 2-phenylethyl, R.sup.2 is methyl or chlorine, n is 1 or 2 and m is 0, 1 or 2, are new compounds possessing pharmacological properties especially indicative of utility in the treatment of migraine.
    Type: Grant
    Filed: December 14, 1977
    Date of Patent: May 6, 1980
    Assignee: May & Baker Limited
    Inventors: Berkeley Basil, Kenneth R. H. Wooldridge
  • Patent number: 4201723
    Abstract: New compounds of the formula (I) ##STR1## wherein R.sub.1 and R.sub.2 each is a saturated or unsaturated, straight-chained or branched alkyl group, an aralkyl group, a saturated or unsaturated cycloalkyl group or an aryl group, orR.sub.1 and R.sub.2 together with the adjacent nitrogen atom forms a substituted or unsubstituted heterocyclic group with or without a further oxygen or nitrogen heteroatom, andR.sub.3 is hydrogen or an acyl group derived from a C.sub.1-18 carboxylic acid. The compounds are prepared by reducing the corresponding nitro compounds of the formula (II) ##STR2## and optionally acylating the obtained product. The compounds of the formula (I) and their acid addition salts and quaternary ammonium salts are active primarily in the induction of liver microsomal enzymes, but they also possess valuable antipyretic activity and a yohimbine lethality increasing effect characteristic of antidepressants.
    Type: Grant
    Filed: June 22, 1977
    Date of Patent: May 6, 1980
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt.
    Inventors: Edit Toth, Jozsef Torley, Eva Palosi, Szaboles Szeberenyi, Laszlo Szporny, Sandor Gorog, Csilla Meszaros
  • Patent number: 4201722
    Abstract: A process is described for the isolation of 4,4'-diaminodiphenylmethane in substantially pure form (of the order of 99% purity) from admixtures thereof with the corresponding 2,4'-isomer and 2,2'-isomer. The dihydrochloride of the isomeric mixture of diamines is heated in the presence of an inert organic solvent with a mixture of isomers of the free diamine, in which the amount of the 4,4'-isomer is at least equal to that of the 2,4'-isomer in the dihydrochloride isomeric mixture. The isomeric mixture of the diamines may be employed in the form of a mixture of polymethylene polyphenyl polyamines containing a major portion of said diamines. The reaction product consists of the insoluble dihydrochloride of substantially pure 4,4'-diaminodiphenylmethane and a solution which is enriched in 2,4'-isomer as compared with the starting mixture of diamines.
    Type: Grant
    Filed: June 4, 1976
    Date of Patent: May 6, 1980
    Assignee: The Upjohn Company
    Inventor: Kwok K. Sun