Abstract: Compounds of the formula ##STR1## where R.sub.4 X is a polycyclocoupled group and R.sub.1 and R.sub.2 are H or simple hydrocarbon and R.sub.3 has the same value and additionally simple acyl, can be made by a variety of syntheses. They have hypolipedemic and antiatherosclerotic properties, and are useful in that field.

Abstract: Dialkylamino- and dialkylaminoalkoxy-substituted aryloxyalkyl diketones, useful as anti-viral agents, are prepared by reacting a dialkylamino-substituted phenoxyalkyl halide with an alkali metal enolate salt of a diketone; or by reacting the corresponding hydroxy-substituted phenoxyalkyl diketone with a dialkylaminoalkyl halide.

Abstract: The present invention relates to novel 2-decarboxy-2-aminomethyl-9-deoxy-9-methylene-16-phenyl-PGF compounds. These compounds are useful pharmacological agents, and are useful for the same purposes as the corresponding PGE-type compounds.

Abstract: A process is provided for making an aromatic polyamine by condensing an aromatic amine with formaldehyde wherein the reaction mixture is maintained at a boiling temperature under reflux and formaldehyde is mixed with the stream of condensed vapors returning to the reactor from the reflux condenser. The process produces a diphenylmethane polyamine particularly well suited for phosgenation to form the corresponding polyisocyanate.

Abstract: New copolymers have been made by reacting a divinyl aromatic compound, e.g., divinyl benzene, with primary or secondary amines, e.g., alkylene diamines or aromatic amines in the presence of a non-hydroxyl strong base, e.g., sodium amide. The reaction may be conducted neat or in an aprotic solvent such as tetrahydrofuran at ambient temperature.The copolymers may be quaternized with alkyl and aralkyl chlorides to give products which are useful algaecides and bactericides. The copolymers themselves can be used in detergents since they have surfactant properties.

Abstract: New dopamine derivatives are disclosed, which are tertiary amines and which exhibit especially dopaminergic properties, and which have the formula ##STR1## wherein R.sub.1 signifies an alkyl group containing at least 4 carbon atoms, a cycloalkyl alkyl group, a cycloalkyl group or a phenylalkyl group and R.sub.2 signifies an alkyl group, a cycloalkyl alkyl group, a cycloalkyl group, or a phenylalkyl group.

Abstract: Compounds having the formula ##STR1## wherein R.sub.1 is hydrogen, alkyl or aryl; R.sub.2 is alkylamino, dialkylamino, or a nitrogen containing heterocyclic group; R.sub.3 is hydrogen, halogen, alkyl, alkoxy or trifluoromethyl; A.sub.1 is an alkylene group; and n is 1, 2 or 3, have useful anti-inflammatory activity.

Abstract: An improved process is described for the preparation of bis(aminophenyl)alkanes which comprises heating the corresponding bis(di-alkoxyphenyl)alkane or corresponding cyclic ethers of bis(phenyl)alkanes with an at least stoichiometric proportion of an aniline acid addition salt, optionally in the presence of an inert organic solvent.

Abstract: A compound of the formula ##STR1## or a pharmaceutically acceptable acid addition salt thereof, in which formula the group R.sup.0 is selected from the group consisting of hydrogen, chlorine, bromine, methyl, trifluoromethyl and methoxy.Pharmaceutical compositions containing these compounds are useful for treatment of depressive disorders.

Abstract: N-phenethyl-N-propyl-3,4-dihydroxyphenethylamine and its non-toxic, pharmaceutically acceptable acid addition salts possessing dopaminergic properties.

Abstract: A process for treating methylene-bridged polyphenylpolyamine mixtures prepared by the silica-alumina catalyzed condensation reaction of aniline and formaldehyde to obtain substantially pure low functionality Diaminodiphenylmethanes having increased 4,4'-positional isomer content and a higher functionality methylene-bridge polyphenylpolyamine mixture having a narrow molecular weight range is disclosed. A methylene-bridge polyphenylpolyamine mixture, prepared by the condensation reaction of aniline and formaldehyde carried out in the presence of a silica-alumina cracking catalyst, containing at least about 75 weight percent diaminodiphenylmethanes based upon the weight of the mixture and having a 4,4'-positional isomer content in the diamine portion of above about 65%, based upon the weight of the diamine portion, is admixed at a temperature of from about room temperature to about 150.degree. C. with a material capable of forming a solution with the mixture at the temperature employed.

Abstract: Novel diphenyl and loweralkyl substituted diphenyl polyamines are useful antimicrobial agents, as well as algae inhibitors. They are especially useful because of their low toxicity, and as such are advantageously included as the active agent in surgical scrubs, antibacterial soaps, as preservatives in cosmetic preparations, and the like. They also can be used for topical treatment of dermatological conditions having a bacterial origin or implication such as Acne vulgaris.

Abstract: The present invention relates to new pharmacodynamically active compounds of the general structure ##STR1## as well as the corresponding amine oxides, quarternary ammonium compounds and salts with physiologically acceptable acids. In formula I R.sup.1 signifies hydrogen, halogen or alkoxy radicals having 1-3 carbon atoms, R.sup.2 and R.sup.3 signify alkyl radicals having 1-3 carbon atoms, which togetner with the carbon atom, to which they are connected, may form a ring, A either signifies a possibly lower alkyl substituted ethylene, trimethylene or tetramethylene group, in which case D is a group ##STR2## wherein R.sup.4 and R.sup.

Abstract: Process for the chlorination of ethylene in which the excess heat of reaction from the chlorination is utilized for fractionation of the reaction product and another dichloroethane containing stream, and in which an impure, neutralized, and dried ethylene dichloride-containing oxychlorination effluent is supplied to the liquid reaction medium in which the chlorination of the ethylene is conducted.

Abstract: Novel bis-basic ethers of 9-substituted phenanthrene and related 10-oxa and 10-aza derivatives, their method of preparation and their use as pharmaceutical agents for the prevention and inhibition of viral infections are disclosed.

Abstract: N-(ortho-substituted benzyl)-dinitro-trifluoromethyl-anilines of the formula ##STR1## in which R is hydrogen, lower alkyl or allyl,One of X and Y is nitro and the other is trifluoromethyl,Q.sub.1 is halogen, lower alkyl or methoxy, andQ.sub.2 is hydrogen, halogen, lower alkyl or methoxy,Are useful as herbicides and plant growth regulating agents, in particular as agents for controlling the growth of tobacco suckers. Particularly useful are those compounds in which R is ethyl, X is nitro, Y is trifluoromethyl, Q.sub.1 is fluorine or chlorine, and Q.sub.2 is hydrogen, methyl, fluorine or chlorine in the 6-position.

Abstract: Aminoalkylnaphthols and esters thereof, useful as cardiotonic agents, prepared from the corresponding RO-naphthalenealkylamines, certain of which are also useful as cardiotonic agents, are disclosed.

Abstract: N,N,N',N'-tetraphenyldiaminomethane, antioxidant for rubber, is prepared by reaction of 2 molar proportions of diphenylamine and 0.8-1.3 molar proportions of formaldehyde at room temperature. The reaction may be carried out in a storage container, for example a thermoplastic container which, holding the tetraphenyldiamonomethane, can be added to and will blend into a rubber mix.

Abstract: Novel amine and amidine derivatives of di-0-(n-higher alkyl and alkenyl)-glycerols and -propanediols, and their pharmaceutically acceptable acid addition salts, are useful for combating viral infections in mammals. Of particular interest is 1,3-di-0-(n-hexadecyl)-2-0-(3-aminopropyl)-glycerol, and its pharmaceutically acceptable acid addition salts.

Abstract: Novel 2-aminomethyleneindanones having analgesic activity are disclosed.