Abstract: The present invention relates to a composition comprising a semi-crystalline, absorbable copolymer formulation wherein the first component is hydroxy-capped polycondensation product of diglycolic acid and a mixture of two idols, diethylene glycol (DEG) and ethylene glycol (EG), with DEG added in larger molar amount, and wherein the second component, glycolide is incorporated during the subsequent ring-opening polymerization. The resulting hydrophilic resin has low crystallinity level, glass transition temperature, Tg, slightly below room temperature, and may be particularly useful for making monofilaments, multifilaments, microspheres, or melt blown nonwoven constructs or other medical devices where fast hydrolysis rates and superior mechanical properties are desirable.
Abstract: A substantially surface active agent-free foamable composition which includes short-chain alcohol, water, polymer, fatty alcohol or fatty acid or a combination of fatty alcohol and fatty acid and propellant. A substantially surface active agent-free foamable composition which includes, water, polymer, fatty alcohol or fatty acid and propellant. A method of treatment using a substantially surface active agent-free foamable compositions.
Type:
Grant
Filed:
January 27, 2012
Date of Patent:
October 27, 2015
Assignee:
Foamix Pharmaceuticals Ltd.
Inventors:
Dov Tamarkin, Enbal Ziv, Yohan Hazot, David Schuz
Abstract: An eye cream comprises the following components: 2-16 parts of pearl, 0.2-2 parts of borax, 10-28 parts of VE, 0.005-0.05 parts of muscone, 0.2-3 parts of borneol, 30-90 parts of eye circles 338Y324 and 0.05-2 parts of zinc carbonate hydroxide in weight. The eye cream has good effects of increasing moisture, continuously locking water, inhibiting melanin, increasing the skin brightness and the skin texture.
Type:
Grant
Filed:
May 3, 2011
Date of Patent:
October 27, 2015
Assignee:
MAYINGLONG PHARMACEUTICAL GROUP CO., LTD
Abstract: A deodorizing composition and method of application thereof for removing and controlling odor-causing organisms that grow on the laundry product residues which deposit on the plumbing of some laundry washing machines. The composition comprises pH adjusting acids and other materials commonly used to retard food spoilage or act as a medical antiseptic, mixed with borax and/or other boron compounds. Sources of peroxides can also be included.
Abstract: Disclosed are compositions comprising nanoparticles and uses thereof. Such nanoparticles include gold nanoparticles conjugated to glucose or a glucose derivative, which are useful as contrast agents in imaging methods such as computed tomography (CT). Nanoparticles disclosed herein are useful in imaging various cells, tissues, and organs, and are particularly useful in imaging tumors and tumor cells in vitro and in vivo.
Type:
Grant
Filed:
July 26, 2010
Date of Patent:
August 18, 2015
Assignees:
The University of Chicago, UChicago Argonne, LLC
Abstract: The invention provides compositions and methods for the treatment of presbyopia. The compositions preferably use aceclidine separate or together with a cycloplegic agent and/or with a nonionic surfactant and viscosity enhancer, and or with low concentrations of a selective ?-2 adrenergic receptor agonist.
Abstract: Novel radiation curable gel-based mammalian nail coating compositions, kits containing these compositions, and methods of their use are disclosed. The novel compositions and/or kits are useful, inter alia, for providing durable, “soak-off” type nail coatings.
Abstract: Novel radiation curable gel-based mammalian nail coating compositions, kits containing these compositions, and methods of their use are disclosed. The novel compositions and/or kits are useful, inter alia, for providing durable, “soak-off” type nail coatings.
Abstract: The present invention is directed to methods for extracting and isolating extracts having angiogenesis inhibiting activity from a latex-containing portion of a Ficus variant, pharmaceutical and nutraceutical compositions comprising the extracts, methods of administering the extracts to treat angiogenesis-dependent diseases and to reduce or inhibit neovessel growth in a subject in need thereof, and the use of the extracts in the manufacture of a composition for reducing or inhibiting neovessel growth.
Type:
Grant
Filed:
August 14, 2009
Date of Patent:
June 30, 2015
Assignee:
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
Abstract: A composition that rejuvenates hair by providing numerous functions for healthy, beautiful hair. The conditioner composition works best after shampooing the hair, whereby oil, grime, and debris are removed and the conditioner can maximize contact with the hair. The composition includes moisturizers that help retain moisture in the hair. The composition also serves as a reconstructor, penetrating the outer cuticle layer of the hair to the cortex and medulla layers of the hair, strengthening its structure through polymer crosslinking. The composition works as an acidity regulator. The composition includes heat absorbing polymers for shielding the hair against excessive heat caused by blow-dryers, curling irons, and hot rollers. The composition includes a surfactant to provide an additional layer to the hair for glossiness. The composition includes vitamins and nutrients efficacious for nourishing the hair follicle and hair strand itself.
Abstract: The invention relates to a method for preparing a cross-linked sterile and homogeneous hydrogel for injection, characterized in that it comprises the following steps: (a) preparing an aqueous solution containing a polymer derived from cellulose and at least one water-soluble polymer, the total polymer content ranging from 0.5 and 5 wt %, preferably from 1 to 4 wt % and more preferably from 1.5 to 3 wt %; (b) optionally adding sold particles; (c) pouring the resulting liquid mixture with the optional solid particles into a vessel and closing dais vessel using a water-tight and gas-tight system; and (d) exposing said vessel containing the liquid and the optional solid particles to a radiation dose of between 5 and 50 kGy, preferably between 20 and 30 kGy, and more preferably of about 25 kGy. The invention also relates to a hydrogel obtained according to the above method and to the use thereof in medical applications.
Abstract: Novel radiation curable gel-based mammalian nail coating compositions, kits containing these compositions, and methods of their use are disclosed. The novel compositions and/or kits are useful, inter alia, for providing durable, “soak-off” type nail coatings.
Abstract: Fill materials for hydrophobic drugs, such as progesterone, and methods of making and using thereof are described herein. The fill material contains the hydrophobic drug dissolved in one or more fatty acids. The concentration of the hydrophobic drug is typically from about 7% to about 50% by weight of the fill material. The concentration of the one or more fatty acids is from about 60% to about 95% by weight of the carrier. The formulation also contains an organic acid and one or both of one or more pharmaceutically acceptable alcohols and one or more pharmaceutically acceptable mono-, di-, or triesters of medium or long chain fatty acids. The fill material can be encapsulated in a hard or soft capsule. The formulations described herein have a higher dissolution rate and faster onset of dissolution compared to micronized progesterone suspended in an oil and thus should have increased bioavailability in vivo.
Type:
Grant
Filed:
April 1, 2010
Date of Patent:
April 21, 2015
Assignee:
Banner Life Sciences LLC
Inventors:
Zhi Liu, Saujanya L. Gosangari, Dana S. Toops, Aqeel Fatmi
Abstract: Dental dressing assemblies are formed from hydrophilic polymer sponge structures, such as a densified chitosan biomaterial. The invention also contemplates systems and methods that can be used in conjunction with stents and periodontal dressings to promote hemostasis and secondary healing in free gingival graft palatal donor sites and all other oral and maxillofacial surgical sites.
Type:
Grant
Filed:
July 12, 2010
Date of Patent:
April 14, 2015
Assignee:
HemCon Medical Technologies, Inc.
Inventors:
Staci Ann McAdams, William David Block, Simon John McCarthy, Kenton W. Gregory, Hal Oien
Abstract: A freshening composition having a malodor control component, about 1% to about 5% of low molecular weight monohydric alcohols, and an aqueous carrier are provided. The composition is essentially free of any material that would soil or stain fabric. The composition may be delivered to fabrics and/or air. The malodor control component may include an effective amount of volatile aldehydes and/or an acid catalyst.
Type:
Grant
Filed:
April 7, 2011
Date of Patent:
March 31, 2015
Assignee:
The Procter & Gamble Company
Inventors:
Ricky Ah-Man Woo, Steven Anthony Horenziak, Rhonda Jean Jackson, Zaiyou Liu, Michael-Vincent Nario Malanyaon, Jason John Olchovy, Christine Marie Readnour
Abstract: The subject invention relates to a variety of formulations of bipolar trans carotenoids including pharmaceutical compositions for oral delivery of a bipolar trans carotenoid comprising i) a bipolar trans carotenoid, ii) a cyclodextrin, and iii) a coating. The invention also relates to preparation of such formulations and their uses.
Abstract: The present invention relates to formulations having an irritation-reducing action, corresponding cosmetic and pharmaceutical products as well as associated methods and uses thereof.
Type:
Grant
Filed:
October 14, 2009
Date of Patent:
February 10, 2015
Assignee:
Symrise AG
Inventors:
Martina Herrmann, Oskar Koch, Imke Meyer
Abstract: The invention relates to a condensation product obtainable by reaction of a1) at least one bicyclic or polycyclic aromatic or heteroaromatic, where the bicyclic or polycyclic aromatic or heteroaromatic is substituted by at least one carboxyl group (—COOH), and where the carboxyl group can be present in salt form, a2) at least one carbonyl compound, a3) if appropriate at least one sulfonating agent, a4) at least one urea derivative, and a5) if appropriate at least one further aromatic or heteroaromatic, or a physiologically tolerable salt thereof.
Type:
Grant
Filed:
November 11, 2008
Date of Patent:
February 3, 2015
Assignee:
BASF SE
Inventors:
Sebastien Garnier, Stephan Hüffer, Günter Scherr, Joachim Roser, Ulrich Mrowietz, Hans Wilhelm Doerr, Jindrich Cinatl, Martin Michaelis
Abstract: The present invention provides methods of treating a human or other mammal infected with a parasitic microorganism by administering an effective amount in unit dosage form of a C8-C16-alpha, beta-unsaturated aliphatic aldehyde, such as trans-2-dodecenal, to the human or other mammal. The parasitic microorganisms may include trypanosomes, bacteria, fungi and nematodes.