Abstract: Methods and system for producing combined photoacoustic/ultrasonic image frames use a low-power narrow beam laser to direct sequential pulses along a path overlying an internal region of interest. Photoacoustic responses are received and used to generate sub-frames. Between each of the laser pulses a plurality of ultrasound pulse-echo beams are sequentially emitted towards the region of interest, and the reflections are received and used to generate ultrasound sub-frames. The photoacoustic sub-frames are combined to produce a photoacoustic frame, and the ultrasound sub-frames are combined to produce an ultrasound frame. The photoacoustic and ultrasound frames are combined to produce an image frame. The method and system are suitable for producing real-time, high-contrast video.

Abstract: The present invention provides an ultrasound diagnostic device including an ultrasound probe including a plurality of ultrasound transducers transmitting ultrasound waves to an object and receiving ultrasound waves reflected from the specimen to output an ultrasound detection signal, a region-of-interest setting unit setting a region of interest within the specimen, and a variation measuring unit measuring a sonic variation or an attenuation variation of ultrasound waves in the region of interest.

Abstract: An examination system including a magnetic resonance scanner having a solenoid for generating a magnetic field, the solenoid surrounding an examination chamber is provided. In addition, a first X-ray source and a first X-ray detector are provided in the examination chamber.

Abstract: A system and method for tracking completeness of co-registered medical image data is disclosed herein. The system and method tracks the position of an anatomical reference marker positionable on a patient and an ultrasound probe during an imaging session and co-registers medical images based on positional data received from the anatomical reference marker and the ultrasound probe. Using the co-registered image data, the system and method generates a surface contour of a region of interest (ROI) of the patient, such as a breast. The surface contour is defined to represent an interface between a chest wall structure and tissue of the ROI in a plurality of co-registered medical images. A completeness map of the image data within the defined surface contour during the imaging session is generated and overlaid on a graphic representation of the ROI.

Abstract: A method for three-dimensional (3D) mapping includes acquiring a plurality of two-dimensional (2D) ultrasonic images of a cavity in a body of a living subject, the 2D images having different, respective positions in a 3D reference frame. In each of the 2D ultrasonic images, pixels corresponding to locations within an interior of the cavity are identified. The identified pixels from the plurality of the 2D images are registered in the 3D reference frame so as to define a volume corresponding to the interior of the cavity. An outer surface of the volume is reconstructed, representing an interior surface of the cavity.

Abstract: Contrast-enhanced image data of breast tissue to be examined is generated. First two-dimensional contrast-agent-influenced x-ray projection data of the breast tissue are acquired at a first x-ray beam energy and a two-dimensional image data record is generated on the basis of the first two-dimensional x-ray projection data. Second two-dimensional contrast-agent-influenced x-ray projection data are acquired from different projection angles at a second x-ray beam energy that differs from the first x-ray beam energy and a three-dimensional tomosynthesis image data record of the breast tissue is reconstructed from the detected second two-dimensional x-ray projection data. Subsequently, a two-dimensional synthetic mammogram is calculated on the basis of the three-dimensional tomosynthesis image data record and a two-dimensional dual-energy mammogram is established by subtracting the image data of the synthetic mammogram from the image data of the two-dimensional image data record.

Abstract: Disclosed are an ultrasound diagnosis apparatus and a method of operating the same, which more accurately measure a cervix length. The ultrasound diagnosis apparatus includes a pressure measurer that measures a pressure value applied from a probe to a cervix, an image generator that scans an object to acquire an ultrasound image, a controller that determines whether a cervix line is included in the ultrasound image, acquires the measured pressure value, corresponding to the ultrasound image, as a first pressure value when the cervix line is included in the ultrasound image, and acquires a second pressure value for measuring a length of the cervix line, and an output unit that outputs pressure information based on at least one selected from the first pressure value and the second pressure value.

Abstract: System and methods are disclosed to facilitate intra-operative procedures and planning. A method can include storing tracking data in memory, the tracking data being generated by a tracking system to represent a location of an object in a tracking coordinate system of the tracking system. The method can also include storing a patient-specific implicit model in memory, the patient-specific implicit model being generated based on image data acquired for the patient to define geometry of an anatomical structure of the patient. The method can also include registering the tracking data and the patient-specific implicit model in a common three-dimensional coordinate system. The method can also include generating an output visualization representing a location of the object relative to the geometry of the anatomical structure of the patient in the common coordinate system.

Abstract: The invention relates to a method and a device for imaging a visco-elastic medium (2). The method comprises an excitation step during which an internal mechanical stress is generated in an excitation zone [A] and an imaging step of acquiring signals during the movements generated by the mechanical stress in the visco-elastic medium (2) in response to the internal mechanical stress in an imaging zone [B] that includes the excitation zone [A]. According to the invention, the method further comprises a step of calculating a quantitative index [Cij] associated with the rheological properties of the visco-elastic medium (2) at at least one point [Bij] of the imaging zone situated at a given depth outside the excitation zone [A].

Abstract: An examination system including a magnetic resonance scanner having a solenoid for generating a magnetic field, the solenoid surrounding an examination chamber is provided. In addition, a first X-ray source and a first X-ray detector are provided in the examination chamber.

Abstract: A method and system for generating an enhanced image of a volume of tissue, the method comprising: emitting acoustic waveforms toward the volume of tissue; detecting a set of acoustic signals derived from acoustic waveforms interacting with the volume of tissue; generating, from the set of acoustic signals, an initial model representing a distribution of an acoustomechanical parameter across a region of the volume of tissue; extracting a set of frequency components, from the set of acoustic signals; generating a first simulated wavefield with a first frequency component of the set of frequency components; generating an updated model of the initial model with the first simulated wavefield; iteratively refining the updated model with a set of simulated wavefields associated with the set of frequency components until a threshold condition is satisfied, thereby producing a final model; and generating the enhanced image from the final model of the volume of tissue.

Abstract: System and method for treating hemorrhoidal piles, addressing both cause and symptoms, by endoluminal/interstitial application of energy are disclosed. The dilated blood arteries in anal/rectal region are irradiated from inside the pile using (laser) energy for minimal pain/discomfort. The center of the pile is irradiated over a certain diameter, absorbing energy; and is denatured causing volume reduction. Central vessels located in the same diameter are obliterated immediately, relieving bleeding. During treatment, new connective tissue replaces the coagulated tissue. Closing inflowing arteries further shrinks piles in weeks to three months. Complications are highly diminished. A hand-piece and a fiber with a sharp distal tip are beneficial. Including an imaging system, (ultrasound imaging, optical coherence tomography) and an intelligent system to calculate necessary laser energy parameters help address each pile individually.

Abstract: A medical probe, consisting of a flexible insertion tube, having a distal end for insertion into a body cavity of a patient, and a distal tip, which is disposed at the distal end of the flexible insertion tube is configured to be brought into contact with tissue in the body cavity. The probe also includes a coupling member, which couples the distal tip to the distal end of the insertion tube and which consists of a tubular piece of an elastic material having a plurality of intertwined helical cuts therethrough along a portion of a length of the piece.

Abstract: Systems and methods for remote photoplethysmography and in particular for determining vital sign information of a subject are provided. The system includes a marker that is applied to a skin of the subject. The marker further includes a first marker area configured to transmit light at a first wavelength and a second marker area configured to transmit light at a second wavelength. The system further includes a detection unit that detects radiation received from the first marker area and from the second marker area of the marker. The system further includes an analysis unit that determines the vital sign information of the subject from the detected radiation from the first marker area and from the second marker area.

Abstract: A method of mapping includes receiving inputs measured by a probe at respective locations inside a body cavity of a subject. At each of the respective locations, a respective contact quality between the probe and a tissue in the body cavity is measured. The inputs for which the respective contact quality is outside a defined range are rejected, and a map of the body cavity is created using the inputs that are not rejected.

Abstract: An electrical insulator is applied to a bone anchor, for instance of a bone implant, such as an external fixation frame, so as to prevent undesirable temperature increases in the bone anchor and surrounding anatomical tissue when subjected magnetic resonance imaging.

Abstract: An apparatus is suitable for measuring a photoplethysmogram (PPG). A photoplethysmographic sensor apparatus may include a casing defining a surface, a plurality of optical emitters configured to emit radiation extending from the surface, at least one photo sensor configured to capture radiation emitted by at least a subset of the plurality of optical emitters. At least a first measurement configuration and a second configuration is defined by the plurality of optical emitters and the at least one photo sensor such that the first and the second measurement configuration provide different measurement channels by including at least partially different sets of at least one optical emitter and at least one photo sensor. The first and second measurement configurations define different spatial configurations, each of which is line symmetric with respect to an imaginary line along the surface.

Abstract: A system and methodology for the automated localization, extraction, and analysis of MRI-based features with clinical information to improve the diagnosis of pelvic organ prolapse (POP). The system can automatically identify reference points for pelvic floor measurements on MRI rapidly and consistent. It provides a prediction model that analyzes the correlation between current and new MRI-based features with clinical information to differentiate patients with and without POP. This system will enable the high throughput analysis of MR images for their correlation with clinical information to better detect POP. The presented system can also be applied to the automated localization and extraction of MRI features for the diagnosis of other diseases where clinical examination is not adequate.

Abstract: Methods, devices and systems for quantifying fluorescence and optical properties in a turbid medium such as tissue are disclosed. One of the methods comprises: providing fluorescence emission and reflectance wavelengths detected from a target surface where each of the detected wavelengths is associated with a respective known distance between a respective excitation source giving rise to the respective detected wavelength and a detector detecting the respective detected wavelength; and calculating the optical properties based on the detected wavelengths and the respective known distances. The known distances may be predetermined to enable calculation of a desired range of values for the optical properties. The calculation of the optical properties may be based on a model of light interaction with the turbid medium where the model limits a range of calculated values for the optical properties.

Abstract: A device for automatically registering the penetration depth of an invasive instrument into an opening and the rotational orientation of an invasive instrument in an opening of a body with the aid of a length-selective and rotation-selective pattern applied to the surface of the instrument, wherein the device has a sensor embodied to surround the instrument in a ring-shaped manner. According to the invention, the sensor is embodied for registering the length-selective and rotation-selective pattern and embodied and provided for the temporary arrangement in the region of the opening for the insertion of the invasive instrument. The device according to the invention has an evaluation unit for evaluating the penetration depth and the rotational orientation of an invasive instrument on the basis of the registered selective pattern.