Patents Examined by Sharon Kennedy
  • Patent number: 7198803
    Abstract: Medicinal preparations containing a drug 2-amino-3-cyano-5-2(2-fluorophenyl) -4-methylpyrrole wherein the QOL and compliance of patients taking this drug can be improved and an unnecessary increase in the drug concentration in the plasma can be prevented by sustaining the release speed of the drug in vivo and lowering the administration frequency of the drug. That is, sustained release oral preparations containing 2-amino-3-cyano-5-(2-fluorophenyl)-4-methylpyrrole as the active ingredient.
    Type: Grant
    Filed: March 19, 2001
    Date of Patent: April 3, 2007
    Assignee: Nippon Shinyaku Co., Ltd.
    Inventors: Hiroyuki Yasuura, Kenya Akada, Shogo Izumi
  • Patent number: 7192436
    Abstract: A system and method for delivering a pledget of hemostasis promoting material to a blood vessel puncture to facilitate hemostasis, having an introducer sheath having an inner diameter and an outer diameter, a control tip coupled to the introducer sheath, and a self-expandable member disposed around a portion of the control tip to control blood flow at the blood vessel puncture.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: March 20, 2007
    Assignee: Sub-Q, Inc.
    Inventors: Eduardo Chi Sing, Luis Urquidi, Mark Ashby, Andrew Cragg, Tom Furey, Robert Bowes, Vincent Tangherlini
  • Patent number: 7182961
    Abstract: This invention concerns an improved particulate composition for delivering a drug to the pulmonary system. Applicants disclose a method of identifying an optimal form of aerodynamically light particles which are highly dispersible. The particles of the instant invention are made by creating hollow, spherical drug particles (i.e., progenitor particles) that collapse in the process of particle formation, leading to wrinkled, thin-walled drug particles of very low envelope density. Additionally, Applicants have found that such particles are especially optimal for inhaled aerosols when the surface area parameter (?) is greater than 2, optimally greater than 3.
    Type: Grant
    Filed: November 20, 2002
    Date of Patent: February 27, 2007
    Assignee: Advanced Inhalation Research, Inc.
    Inventors: Richard P. Batycky, David A. Edwards, Michael M. Lipp
  • Patent number: 7182955
    Abstract: The invention comprises a transdermal dosage form comprising a active agent component comprising a polymeric matrix and an abusable drug substance, an overlay backing, a porous material, and an antagonist reservoir comprising an antagonist to the abusable drug substance. The porous material adjoins the antagonist reservoir and is in fluid communication with the skin-contacting surface defined by the active agent component. In one embodiment, the device comprises a barrier layer interposed between the active agent component and the antagonist reservoir.
    Type: Grant
    Filed: December 23, 2003
    Date of Patent: February 27, 2007
    Assignee: 3M Innovative Properties Company
    Inventors: John R. Hart, Deanna L. Stebbings
  • Patent number: 7184826
    Abstract: A percutaneous agent delivery or sampling device comprising a sheet having a plurality of microblades for piercing and anchoring to the skin for increasing transdermal flux of an agent and for improving the attachment of the device to the skin.
    Type: Grant
    Filed: June 17, 1997
    Date of Patent: February 27, 2007
    Assignee: Alza Corporation
    Inventors: Michel J. N. Cormier, Armand P. Neukermans, Barry Block, Felix T. Theeuwes, Alfred A. Amkraut
  • Patent number: 7175609
    Abstract: Syringes and methods of using are described which protect the syringe barrel cavity from contaminants. A first syringe is formed with a corrugated sheath which encloses the plunger and space between the rearward end face surface of the syringe barrel handle member and the forward face of the plunger handle member. A second syringe is formed with a syringe barrel having a straight segment and a corrugated segment having the forward face of the plunger handle member molded to the rearward terminus of the corrugated segment of the syringe barrel. A third syringe is formed from mating syringe barrel and plunger member walls. The walls of the mating syringe barrel and plunger member are concentric and slide relative to each other while maintaining an enclosure around the plunger shaft. A fourth syringe is formed from inner and outer concentric syringe barrel walls mating with the walls of a plunger member.
    Type: Grant
    Filed: September 24, 2004
    Date of Patent: February 13, 2007
    Inventor: Robin Scott Gray
  • Patent number: 7175608
    Abstract: The invention provides devices and methods for identification of an epidural space. The invention also provides for visually determining when a needle enters the epidural space.
    Type: Grant
    Filed: March 20, 2003
    Date of Patent: February 13, 2007
    Inventors: Maan Hasan, Jim Roberts
  • Patent number: 7172579
    Abstract: The present invention provides a system and method for irrigating and collecting tissue from a body cavity in a patient. The system includes an irrigation and collection device for injecting an irrigation fluid into the body cavity. The irrigation device injects fluid into the body cavity by creating a positive pressure within the device to expel the irrigation fluid from the device into the body cavity. The irrigation fluid is evacuated from the body cavity by the resulting negative pressure within the device, drawing the irrigation fluid and any loose tissue or particulate material into the device. The irrigation fluid is filtered, collecting the evacuated tissue and particulate material in a collection receptacle thereby isolating the evacuated tissue and particulate material within the irrigation fluid.
    Type: Grant
    Filed: May 7, 2004
    Date of Patent: February 6, 2007
    Assignee: CIVCO Medical Instruments Co., Inc.
    Inventors: Winston E. Barzell, Willet F. Whitmore
  • Patent number: 7169404
    Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising a biologically degradable, biologically erodable, and/or biologically resorbable ABA or AB block copolymer. A biologically active agent can be conjugated to the block copolymer.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: January 30, 2007
    Assignee: Advanced Cardiovasular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Eugene T. Michal, Yiwen Tang
  • Patent number: 7163521
    Abstract: An integrated infusion and aspiration system includes a flow control system and a catheter assembly. The catheter assembly includes an infusion catheter and an aspiration catheter, each having ports located at the distal end of thereof. The distal ends of the catheters are separated so that the aspiration catheter ports can be positioned on an opposing side of a surgical wound site from the infusion catheter ports. Methods of operation of the integrated infusion and aspiration system provide for uninterrupted aspiration with concurrent controlled delivery of an infusion solution such that the infusion solution is substantially evenly dispersed of over the wound site.
    Type: Grant
    Filed: July 22, 2004
    Date of Patent: January 16, 2007
    Assignee: Breg, Inc.
    Inventors: E. Marlowe Goble, Mark E. Howard, Jeffrey T. Mason, T. Wade Fallin
  • Patent number: 7164942
    Abstract: A device is provided for treating skin on the body of a subject. The device includes a plurality of electrodes, which are adapted to be placed in contact with the skin and then moved across the skin while maintaining electrical contact with the skin. The device additionally includes a power source, which is adapted to apply a current between two or more of the plurality of electrodes at the same time as the electrodes are being moved across the skin.
    Type: Grant
    Filed: February 9, 2004
    Date of Patent: January 16, 2007
    Assignee: Transpharma Medical Ltd.
    Inventors: Zohar Avrahami, Ze'ev Sohn
  • Patent number: 7160265
    Abstract: The invention relates to a needle-less injection device, comprising a cannula (5) which can be inserted in a housing (3), can be filled with a predetermined active substance (11) for injection, and comprises a piston (9) movable in a cannula housing for ejecting the active substance (11) from an outlet opening (53) in the cannula housing, and a propellant charge cartridge (7) insertable into the housing (3) and comprising a housing containing a propellant charge (19) and a device (23) for igniting the propellant charge, and a propelling surface (15) movable in a part (3a) of the housing of the injection device (1) or in the housing of the cannula (5) or in the cartridge housing and movable by the gas pressure, after ignition of the propellant charge (19), out of a starting position into an end position, the outer periphery of the propelling surface being sealed from the inner periphery of each housing during the entire displacement travel also, wherein the propelling surface (15) acts upon the piston (9) mova
    Type: Grant
    Filed: June 20, 2001
    Date of Patent: January 9, 2007
    Inventor: Peter Lell
  • Patent number: 7160272
    Abstract: A medical valve includes a valve body having a central fluid passageway defined therein. A movable piston adapted in size and shape to be located within said central fluid passageway of said valve body. A sealing interface is defined between said movable piston and said central fluid passageway. An upper seal is located at an upper portion of said sealing interface. It is formed by a seal carried by said valve body. A lower seal is located at a lower portion of said sealing interface, and is formed by a seal carried by said movable piston. The lower seal remains intact until after said upper seal is broken.
    Type: Grant
    Filed: June 2, 2003
    Date of Patent: January 9, 2007
    Assignee: Elcam Plastic
    Inventors: Ronen Eyal, Claude A. Vidal, Russell A. Redmond, David A. Chandos
  • Patent number: 7153288
    Abstract: A dual port syringe has an upper port for connection to a fluid reservoir and a lower port for delivery of the medical fluid under pressure to a patient. A first valve is connected between the fluid reservoir and the upper port, and second valve is connected between the lower port and the patient. During a fill operation, a piston is moved within the syringe to drawn fluid from the reservoir into the syringe through the upper port. During injection operation, the piston moves in an opposite direction to force fluid out of the syringe through the lower port.
    Type: Grant
    Filed: August 9, 2005
    Date of Patent: December 26, 2006
    Assignee: Acist Medical Systems, Inc.
    Inventors: Doug Duchon, Thomas Paulson, Vince Copa, Robert F. Wilson, Jiyan Liu
  • Patent number: 7153291
    Abstract: A securement device includes a simply-structured retention mechanism that permits a portion of a catheter hub or a similar medical article to be easily anchored to a patient, without the use of tape or needles and suturing. A unitary retainer desirably includes a base defining a locator mechanism. The locator mechanism interacts with a fitting of the medical device so as to position the medical device relative to the retainer. The locator mechanism also desirably guides the medical device fitting into contact with an adhesive member mounted on an outer surface of the retainer. In one form, the locator mechanism includes one or more posts that engage mating holes defined in the medical device fitting. In other forms, the locator mechanism includes a cradle defining an arcuate channel to receive a convex surface of the medical device, or a recess shaped to matingly receive the fitting.
    Type: Grant
    Filed: December 23, 2003
    Date of Patent: December 26, 2006
    Assignee: Venetec International, Inc.
    Inventor: Steven F. Bierman
  • Patent number: 7150741
    Abstract: The invention is directed to a dose control module for manipulating the dosage of one or more pharmaceutical solutions emanating from an implantable drug infusion pump. The dose control module has a processor and other circuitry for manipulating flow valves and other dose manipulators. Effluent catheters from one or more implantable drug infusion pumps may be connected to the dose control module. The dose control module may direct the effluent pharmaceutical solution to one or more catheters. These catheters direct the pharmaceutical solutions to treatment locations. The invention is also directed to induction coil valves for use in or with the dose control module. The use of induction coils permits the dose control module to determine valve position and counteract large directional magnetic fields produced by MRIs.
    Type: Grant
    Filed: December 30, 2002
    Date of Patent: December 19, 2006
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventors: John Erickson, Brian Blischak, Terry Daglow
  • Patent number: 7147625
    Abstract: An accessory is connected between a leg bag and a urinary catheter to prevent microorganisms migrating from the leg bag up through the catheter. The accessory has a sleeve, connectors to connect the sleeve to the leg bag and to the urinary catheter, a filter positioned within the sleeve that can be coated with an antimicrobial composition, and a valve to prevent fluid from moving from the leg bag to the catheter. The antimicrobial coated sleeve can be used with or with out the filter. The filter is made by compounding a polymeric resin powder with an antimicrobial composition.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: December 12, 2006
    Assignee: ICET, Inc.
    Inventors: Shantha Sarangapani, Fletcher Tifft Longley
  • Patent number: 7144384
    Abstract: A device for delivering fluid to a patient including an exit port assembly, a reservoir including a side wall extending towards an outlet connected to the exit port assembly, a threaded lead screw received at least partly in the reservoir and longitudinally extending towards the outlet, and a plunger secured to the lead screw and having an outer periphery linearly slideable along the side wall of the reservoir. A tube is coaxially received on the lead screw and includes a longitudinal slot, a pin extending through the lead screw and the slot of the tube, and a gear is secured to the tube for rotation therewith.
    Type: Grant
    Filed: September 30, 2002
    Date of Patent: December 5, 2006
    Assignee: Insulet Corporation
    Inventors: William Gorman, John T. Garibotto, J. Christopher Flaherty, John R. Bussiere, Gaurav Rohatgi
  • Patent number: 7141042
    Abstract: A method for lubricating a sealing member in a drug delivery device includes the steps of washing and rinsing the sealing members in hot deionized water following by drying the sealing members. The dried sealing members are tumbled with polymeric silicone and then irradiated at a target dose between 2.5 and 4.0 Mrads. The irradiated sealing members are then utilized in a variety of drug delivery devices including syringes, pre-filed syringes, drug cartridges, and needleless injector ampules.
    Type: Grant
    Filed: December 14, 2000
    Date of Patent: November 28, 2006
    Assignee: Becton Dickinson and Company
    Inventor: Thea E. Lubrecht
  • Patent number: RE39499
    Abstract: Compressible lock washers for use in catheter connectors. One such lock washer (60) includes a support ring (62) and tube engagement flanges (64) extending centrally therefrom, oblique to the ring and each extending from the same side thereof. The tube engagement flanges (64) define a tube receptacle (72) through which a catheter tube (58) may be inserted. Upon compression of the lock washer (60), the tube engagement flanges (64) are force toward the ring (62), decreasing the diameter of the tube receptacle (72). Thus, during compression of the lock washer (60), the tube engagement flanges (64) engage the catheter tube (58) which runs through the tube receptacle (72), securing the catheter tube within the catheter connector (20) with which the lock washer is associated.
    Type: Grant
    Filed: November 29, 2001
    Date of Patent: February 27, 2007
    Assignee: Epimed International, Inc.
    Inventor: Nicholas Sandor Racz