Patents Examined by Sikarl A. Witherspoon
  • Patent number: 10894766
    Abstract: The present invention deals with a process for the production of alkanesulfonic acids, in particular methanesulfonic acid, and a method of purification of the raw products.
    Type: Grant
    Filed: May 23, 2018
    Date of Patent: January 19, 2021
    Assignee: BASF SE
    Inventors: Jan Spielmann, Juergen Wortmann, Frieder Borgmeier, Michael Zeilinger, Rosario Mazarro Berdonces, Bjoern Kaibel
  • Patent number: 10888537
    Abstract: The present disclosure relates to, inter alia, pharmaceutical compositions comprising omega-3 fatty acids.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: January 12, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Mehar Manku, Jonathan Rowe
  • Patent number: 10889536
    Abstract: Disclosed are enol ethers compounds. The enol ethers exhibit low volatile organic content and are useful in a variety of chemical applications. The enol ethers can be used in applications as diluents, wetting agents, coalescing aids, paint additives and as intermediates in chemical processes. The enol ethers also have particular utility as film-hardening additives in coating formulations.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: January 12, 2021
    Assignee: Eastman Chemical Company
    Inventors: Matthew Allen Boone, Stephanie Kay Clendennen
  • Patent number: 10875821
    Abstract: Process for the preparation of alpha, beta unsaturated aldehydes by oxidation of alcohols in the presence of a liquid phase wherein the liquid phase contains 0.1 to less than 25 weight-% water and wherein the liquid phase contains at least 25 weight-% of alcohol(s) of general formula (II) and alpha, beta unsaturated aldehyde(s) of general formula (I) and wherein the oxidant is oxygen and/or hydrogen peroxide.
    Type: Grant
    Filed: March 12, 2018
    Date of Patent: December 29, 2020
    Inventors: Nicolas Vautravers, Joaquim Henrique Teles, Andreas Keller, Kirsten Braunsmann, Andreas Jörg Ufer, Stefan Bauer, Marco Bosch, Vera Luense, Joseph John Zakzeski, Michaela Fenyn
  • Patent number: 10870665
    Abstract: A cocrystal having the formula LiX.aM, or a solvate or hydrate thereof, wherein X is a conjugate base of an organic acid, M is a neutral organic molecule, and a is from 0.5 to 4, pharmaceutical compositions comprising such cocrystals, cocrystal solvates, or cocrystal hydrates, and methods of preparing such cocrystals, cocrystal solvates, or cocrystal hydrates, and such pharmaceutical compositions.
    Type: Grant
    Filed: August 28, 2019
    Date of Patent: December 22, 2020
    Assignee: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Michael John Zaworotko, Naga Duggirala, Adam John Smith, Roland Douglas Shytle
  • Patent number: 10865174
    Abstract: A one-step process for hydroformylation of olefins can include iron-catalyzed hydroformylation of olefins. The process can result in the conversion of olefin in the range of 40 to 99%. A reaction mixture includes iron precursor, ligand, substrate and solvent. The reaction mixture can be pressurized with syngas (CO/H2) under constant stirring to obtain a desired aldehyde compound. The ligand can be a monodentate ligand of a phosphines or a phosphite, and the iron precursor can be [HFe(CO)4]?.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: December 15, 2020
    Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIALRESEARCH
    Inventors: Samir Hujur Chikkali, Swechchha Pandey
  • Patent number: 10865171
    Abstract: Disclosed is a method for making aromatic enol ethers that have utility as film-hardening additives for coating formulations. The aromatic enol ethers have particular utility as film-hardening additives for water-based coating formulations. The aromatic enol ethers provide improvements in hardness and hardness related properties such as block resistance without contributing to the volatile organic content of the composition.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: December 15, 2020
    Assignee: Eastman Chemical Company
    Inventor: Matthew Allen Boone
  • Patent number: 10865173
    Abstract: An allylic oxidation process includes forming a mixture containing ?-Guaiene and an iron (III)-X porphyrin complex catalyst in a sustainable solvent, introducing molecular oxygen into the mixture, and effecting allylic oxidation to produce an ?,ß-unsaturated ketone, Rotundone.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: December 15, 2020
    Assignee: GIVAUDAN S.A.
    Inventors: Fridtjof Schröder, Nicole Pfeiffer
  • Patent number: 10864271
    Abstract: Disclosed is a method of treating a tumor in a patient, comprising (a) administering riluzole in an amount effective to sensitize the tumor cells to ionizing radiation, and (b) irradiating the tumor cells with ionizing radiation in a dose effective to reduce tumor cell growth. The method can further comprise administering an effective amount of one or more additional therapeutic agents.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: December 15, 2020
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Atif Jalees Khan, Suzie Chen, James S. Goydos, Bruce G. Haffty
  • Patent number: 10865172
    Abstract: Disclosed are aromatic enol ethers that have utility as film-hardening additives for coating formulations. The aromatic enol ethers have particular utility as film-hardening additives for water-based coating formulations. The aromatic enol ethers provide improvements in hardness and hardness related properties such as block resistance without contributing to the volatile organic content of the composition.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: December 15, 2020
    Assignee: Eastman Chemical Company
    Inventor: Matthew Allen Boone
  • Patent number: 10864459
    Abstract: Various aspects of this patent application relate to methods to separate a cannabinoid molecule from other molecules of a decarboxylated cannabinoid extract.
    Type: Grant
    Filed: November 13, 2019
    Date of Patent: December 15, 2020
    Assignee: Natural Extraction Systems, LLC
    Inventors: Robert C. Wagner, C. Russell Thomas, Douglas G. Metcalf
  • Patent number: 10858304
    Abstract: Disclosed are novel aromatic enol ethers. The aromatic enol ethers exhibit low volatile organic content and are reactive film-hardening compounds. The aromatic enol ethers are useful in a variety of chemical applications. The aromatic enol ethers can be used in applications as plasticizers, diluents, wetting agents, coalescing aids and as intermediates in chemical processes. The aromatic enol ethers also have utility as film-hardening additives for coating formulations.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: December 8, 2020
    Assignee: Eastman Chemical Company
    Inventor: Matthew Allen Boone
  • Patent number: 10851043
    Abstract: Fatty acids play very important and diverse roles in living organisms, from signal transduction, energy management, maintaining of structural integrity to the normal metabolic processes. Due to its diverse presence and roles, Fatty Acid Synthase (FAS) is an attractive drug target under different pathologic contexts such as cancer, TB, obesity, microbial infection, etc. There are a number of molecules targeting Fatty Acid Synthase (FAS) in the prior art like Cerulenin, Orlistat, Pyrimidine, Triclosan, C75 etc. The present invention relates to a compound of formula I having fatty acid synthase inhibitory properties which was confirmed by an FAS inhibition assay. The present invention also relates to a process for collection, extraction, isolation, purification and characterization of the claimed compound from marine cyanobacterium, Phormidium ambiguum.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: December 1, 2020
    Assignee: KANNUR UNIVERSITY
    Inventors: Sabu Abdulhameed, Madathilkovilakath Haridas, Prasanth Shankar
  • Patent number: 10843990
    Abstract: This invention relates to a one-pot synthesis of a high-purity calix[4]arene compound by reacting a phenolic compound and an aldehyde in the presence of at least one nitrogen-containing base as a catalyst to form the calix[8]arene compound, and cleaving the calix[8]arene compound into a high-purity calix[4]arene compound, directly, without carrying out a purification step before the cleaving step. The invention also relates to an improved conversion of a calix[8]arene compound to a calix[4]arene compound, by cleaving a calix[8]arene compound in a glycol ether solvent having a boiling point of at least about 200° C., to result in a high-purity calix[4]arene compound, without using an antisolvent.
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: November 24, 2020
    Assignee: SI GROUP, INC.
    Inventors: Cornelius Haase, Jeff Hiscock, Philip David Atwood
  • Patent number: 10843991
    Abstract: A method for purification and separation of cannabinoids, such as cannabidiol and tetrahydrocannabinol, e.g., from dried hemp and cannabis leaves can use a continuous simulated moving bed process, a batch column chromatography method, or a single column, and a combination of one or more of a sequence of purification steps including: filtration, decolorization, activation or decarboxylation, dewaxing, polishing, and crystallization to separate a cannabinoid from the cannabis plant and to provide various cannabinoid products. The cannabinoid products can be used in various pharmaceutical and nutraceutical applications.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: November 24, 2020
    Assignee: Orochem Technologies Inc.
    Inventors: Anil Rajaram Oroskar, David W. House, Praneeth Dayanthe Edirisinghe, Asha Anil Oroskar, Faridedin Adel, Xinjie Chen, Gautham Anil Oroskar, Kunal Gulati
  • Patent number: 10844295
    Abstract: Systems and methods for reducing olefin concentration in a hydrocarbon stream comprising aromatic compounds and olefins, the method including supplying an aromatic-rich olefinic hydrocarbon stream; combining the aromatic-rich olefinic hydrocarbon stream with a catalyst; heating the aromatic-rich olefinic hydrocarbon stream and the catalyst to effect a reaction selected from the group consisting of: oxidation of olefins; hydration of olefins; and combinations of the same; separating an aqueous phase from a produced hydrocarbon phase; and separating C7 compounds from C8+ compounds in the produced hydrocarbon phase.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: November 24, 2020
    Assignee: SAUDI ARABIAN OIL COMPANY
    Inventors: Omer Refa Koseoglu, Robert Peter Hodgkins
  • Patent number: 10836699
    Abstract: Provided is a process for preparing methacrolein which maximizes capture of methanol. Also provided are processes for producing methacrylic acid and methyl methacrylate.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: November 17, 2020
    Assignee: Rohm and Haas Company
    Inventors: Reetam Chakrabarti, Dmitry A. Krapchetov, Mark A. Silvano, Jinsuo Xu
  • Patent number: 10836698
    Abstract: Provided is a process for preparing dry methacrolein which maximizes capture of methanol. Also provided is a process for producing methyl methacrylate.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: November 17, 2020
    Assignee: Rohm and Haas Company
    Inventors: Reetam Chakrabarti, Charles Como, Sarah L. Hruby, Dmitry A. Krapchetov, Minh N. Ngo, Muhunthan Sathiosatham, Mark A. Silvano
  • Patent number: 10835839
    Abstract: Purified and modified Cannabis products and methods for producing the same. The purified Cannabis product comprises substantially no volatile organic compounds while retaining Total Potential cannabinoid content. The modified Cannabis product comprises a purified Cannabis product modified by at least one added volatile unsaturated hydrocarbon. The modified Cannabis product is formed by extracting a volatile organic compound from a Cannabis raw material to form a purified Cannabis product, and then adding the at least one volatile unsaturated hydrocarbon to the purified Cannabis product to form the modified Cannabis product and cause an enhanced user experience during combustion and inhalation of the modified Cannabis product.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: November 17, 2020
    Assignee: HIGH SIERRA TECHNOLOGIES, INC.
    Inventor: Vincent C. Lombardi
  • Patent number: 10836718
    Abstract: The invention describes a process for making astacene of formula 1, the exocyclic double bonds thereof having either an E configuration or an E- and/or Z-configuration, wherein astaxanthin of the general formula 2 having asymmetric centers 3 and 3?, each of which respectively having an (S)- or (R)-conformation and the exocyclic double bonds of said astaxanthin 2 having either an E- or E- and/or Z configuration, is oxidized in the presence of at least one tertiary alcoholate.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: November 17, 2020
    Assignee: BASF SE
    Inventors: Bernd Schaefer, Wolfgang Siegel