Abstract: A process for preparing C5 aldehydes involves hydroformylation of butenes with synthesis gas in the presence of a homogeneous catalyst system and a solvent. It is a feature of the process that the aldehyde concentration in the reaction mixture is limited.

Abstract: A process can be used for preparing aldehydes from C2 to C20 olefins with a subsequent thermal separation for removal of the aldehyde formed. The process involves a membrane separation, which is preceded by performance of a gas exchange by which the proportion of the partial pressure represented by carbon monoxide or hydrogen is increased in order to reduce catalyst losses.

Abstract: Various embodiments disclosed relate to bridged phthalocyanine- and napththalocyanine-metal complex catalysts and methods using the same for oxidation reactions. In various embodiments, the present invention provides a method of oxidation including contacting an oxidizable starting material including an alkene with a catalyst and an oxidant, to provide an oxidized product.

Abstract: A new heterogeneous catalyst for various organic oxidation processes and a method of making the same by a successful immobilization of a copper (II) bis-Schiff base hydrazone complex on the surface of a composite ZnO—TiO2 to afford as active catalyst CuL2Cl2@ZnO—TiO2. This novel catalyst can be used to selectively oxidize benzyl alcohol to benzaldehyde.

Abstract: A process for preparing aldehydes by a homogeneously catalysed hydroformylation of C4 to C20 olefins involves withdrawing a biphasic stream (liquid/gaseous) and expanding in two stages. Before, between, or after the two stages, the liquid phase is cooled. Only after expansion and cooling is the homogeneously dissolved rhodium catalyst system separated from the residual stream.

Abstract: Disclosed is a method of treating a tumor in a patient, comprising (a) administering riluzole in an amount effective to sensitize the tumor cells to ionizing radiation, and (b) irradiating the tumor cells with ionizing radiation in a dose effective to reduce tumor cell growth. The method can further comprise administering an effective amount of one or more additional therapeutic agents.

Abstract: A method for synthesizing pitavastatin tert-butyl ester includes obtaining a substance B through reacting (4R-CIS)-6-chloromethyl-2,2-dimethyl-1,3-dioxolane-4-acetic acid tert-butyl ester with a substance A under the action of a first base catalyst, 5 oxidizing with an oxidizing agent to obtain a substance C, then reacting with 2-cyclopropyl-4-(4-fluorophenyl)-quinoline-3-formaldehyde under the action of a second base catalyst to obtain a substance D, and finally, carrying out an acid deprotection to obtain pitavastatin t-butyl ester. The reaction conditions of the present invention are mild and controllable, and the reaction conditions of the synthesis of the Julia olefination do 10 not require an ultra-low temperature reaction. The operation is convenient and simple, the stereoselectivity is good, the yield is high, and the synthesized pitavastatin t-butyl ester is a completely non-cis isomer, and its purity is high.

Abstract: A process for producing acetonitrile, the process comprising: treating a feedstock stream comprising methanol, allyl alcohol, oxazole, acetonitrile, water, and hydrogen cyanide to remove hydrogen cyanide and produce an acetonitrile stream comprising less than 1 wt. % hydrogen cyanide. The process further comprises the step of distilling the acetonitrile stream in a first distillation column to produce a first distillate comprising oxazole and methanol; a first intermediate acetonitrile stream comprising acetonitrile and oxazole and less than 1 wt % allyl alcohol; a first bottoms stream comprising allyl alcohol and water. The process further comprises the step of purifying the first intermediate acetonitrile stream to produce an acetonitrile product stream and a recycle stream comprising allyl alcohol.

Abstract: Disclosed herein are embodiments of a method for making substituted furan compounds using bioderived coupling partners and a heterogeneous catalyst. In particular disclosed embodiments, the method comprises coupling a furan compound with the coupling partner (e.g., an aliphatic or heteroaliphatic coupling partner) in the presence of the heterogeneous catalyst to provide the substituted furan compound.

Abstract: A system and method for producing minerals from divalent ion-containing brine stream includes rejecting sulfate from a divalent-ion rich reject stream in a first nanofiltration seawater reverse osmosis (NF-SWRO) unit, producing solid calcium sulfate dihydrate and a magnesium-rich brine stream in a first concentration unit, concentrating the magnesium-rich brine stream to a saturation point of sodium chloride in a second concentration unit, producing solid sodium chloride and a supernatant product stream in a first crystallizing unit, produce a concentrated magnesium-rich bittern stream from the supernatant product stream in a third concentration unit, and at least one of producing hydrated magnesium chloride from the concentrated magnesium-rich bittern stream in a second crystallizing unit and producing anhydrous magnesium chloride by prilling the concentrated magnesium-rich bitterns stream under a hydrogen chloride atmosphere in a dry air process unit.

Abstract: Provided is a hydrophilic phosphorus ligand with the structure of formula 1. X is Y is m is an integer from 1 to 20, A independently is *—O(CH2)n—, n is an integer from 1 to 5, *— is a bond close to triphenylphosphine, and — is a bond away from triphenylphosphine.

Abstract: A method of separating actinium and/or radium from proton-irradiated thorium metal. The thorium metal is irradiated to produce isotopes including thorium, actinium and/or radium. The resultant product is dissolved in solution and a selective precipitant is used to precipitate a bulk portion of the thorium. The precipitated thorium can be recovered. Chromatography is carried out on the remaining solution to remove residual thorium and to separate the actinium from the radium.

Abstract: Provided are novel treprostinil based compounds, methods of treatment using the same, and their methods of making.

Abstract: Crystallized cannabis extract having a purple color is made by first providing cannabis having a detectable amounts of tetrahydrocannabinolic acid (THCA) as well as secondary components including terpenes. Pentane or other solvent is added to the cannabis material to dissolve the secondary components. The cannabis material is enclosed in a filter basket, or a rosin press filter bag, having an average pore diameter of 25 microns. The centrifuge spins the filter bag or filter basket to separate the THCA from the cannabis material and thereby yielding a primary product that is a concentrated cannabis material having at least 95% THCA and a secondary product (high terpene extract) having combined THCA and secondary components including terpenes. The concentrated cannabis material is distilled in a wiped film evaporator or a short path evaporator to oxidize the concentrated cannabis material and yield a super concentrated cannabis material having at least 98% THC.

Abstract: A method for purification and separation of cannabinoids, such as cannabidiol and tetrahydrocannabinol, e.g., from dried hemp and cannabis leaves can use a continuous simulated moving bed process, a batch column chromatography method, or a single column, and a combination of one or more of a sequence of purification steps including: filtration, decolorization, activation or decarboxylation, dewaxing, polishing, and crystallization to separate a cannabinoid from the cannabis plant and to provide various cannabinoid products. The cannabinoid products can be used in various pharmaceutical and nutraceutical applications.

Abstract: Systems and methods for removing one or more pesticides from a cannabis product are provided. The method includes dissolving, in a solvent, a cannabis product including one or more pesticides, forming a dissolved solution, and cooling the dissolved solution to a cooling temperature, causing the cannabis product to precipitate from the dissolved solution, wherein, at the cooling temperature, the one or more pesticides remain dissolved in the dissolving solution. The method further includes removing the precipitated cannabis product from the dissolving solution. The disclosed method is suitable for removing one or more pesticides from various cannabis products containing natural cannabinoids, cannabinoids acetates, cannabinoid carboxylates, or the like.

Abstract: A mathematical model was developed to lead to the design of a novel membrane, which can operate in membrane distillation at a small trans-membrane temperature gradient, including at low feed water temperature range. The novel membrane design can be described as a super-hydrophobic nano-porous/micro-porous composite membrane. This membrane will significantly decrease the energy requirements of the MD process since it can operate at very low inlet feed temperatures.

Abstract: A process for the treatment of waste water, spent air, and hydrocarbon containing liquid and gaseous streams in the cumene/phenol complex is described. Various effluent streams are combined in appropriate collection vessels, including a spent air knockout drum, a hydrocarbon buffer vessel, a fuel gas knockout drum, a phenolic water vessel, and a non-phenolic water vessel. Streams from these vessels are sent to a thermal oxidation system.

Abstract: Process for hydroformylation of olefins using Pt and iodine.

Abstract: A formulation includes an active agent, a thickening/solidifying agent, and an antioxidant. The active agent is 9-cis-?-carotene (9CBC) or a derivative thereof of the following formula: where R2 is H or methyl; X is optionally substituted with one or more methyl groups; n is an integer of 0-16; and the asterisk represents the point of attachment to the cyclohexene ring.