Abstract: A delayed-release composition composed of a Lactobacillus bacterium, Bifidobacterium longum, Streptococcus thermophlus, inulin and xylooligosaccharide is provided for use in reducing nitrogenous waste products in the blood and treating renal failure.
Abstract: A formulation includes a cannabinoid extract that is pharmaceutically effective by systemic delivery via a recipient's oral mucosal lining. The method of delivery avoids the digestive tract processing and liver metabolizing of the active ingredients of the formulation, whereby lower doses cause a desired therapeutic effect or other intended effect. Variations of the formulation include a cannabinoid extract and one or more of pregelatinized tapioca starch polymethylsilsesquioxane, bromelain, volume Fenugreek gum, vitamin B12, luo han guo fruit extract, mannitol, microcrystalline cellulose, sodium alginate, gellan gum, menthol Natural peppermint flavor or oil, Grapefruit flavored powder or oil, magnesium stearate and/or citric acid. The cannabinoid extract may include Tetrahydrocannabinol, tetrahydrocannabinolic acid, Cannabidiol, Cannabidiol acid, and/or other cannabinoid sourced from a Cannabis sativa plant.
Abstract: Disclosed are novel processing methods for green coffee beans that result in novel green coffee bean products, including products that incorporate whole green coffee beans. Methods include selecting whole coffee beans in their fresh green unroasted state with naturally-occurring levels of phytonutrients, sterilizing and drying them, applying iterative grinding processes and stabilization techniques, all while avoiding high temperatures. Whole green coffee bean products created and defined by these methods are used to treat or prevent diabetes and obesity.
Abstract: A multi-phase treatment of a respiratory disease in which one treatment is a lysing defense by applying inhibitory agents to respiratory passages. Application may be by nasal irrigant, oral gargling mouthwash, or smelling salt. Another treatment is an immune system suppressing defense by providing a liposome-based countermeasure to excess activity of the host immune system during COVID-19 infection. The liposome increases bio-activity of probiotics, probiotics-produced therapeutic peptides, bio-peptides, and antioxidant level in the blood with a sustained massive dose of antioxidants to counteract excess oxidation produced by excess activity of the host immune system, when administered through oral route.
Abstract: Disclosed are a traditional Chinese medicine composition for treating tumours and a preparation method therefor, wherein the composition is prepared from Sophora flavescens, wild Chrysanthemum flower, honeysuckle, mint, Poria cocos, Atractylodes lancea, cinnamon, clove, Astragalus, Ganoderma lucidum, Ligusticum striatum, Aucklandia root and Radix glycyrrhizae. The traditional Chinese medicine composition has an anti-tumour effect.
Abstract: The invention relates to a feijoa fruit extract. In particular the invention relates to therapeutic uses of a feijoa fruit extract, processes for preparing the extract, and compositions comprising the extract. The feijoa fruit extract of the invention can be used in the treatment and prevention of rheumatoid arthritis and Type-2 diabetes.
Abstract: The present disclosure relates to a composition for preventing, alleviating or treating stress diseases, containing a Platycodon grandiflorum extract as an active ingredient, and, more specifically, to a food composition for preventing or alleviating stress diseases or a pharmaceutical composition for preventing and treating stress diseases, both of which contain a Platycodon grandiflorum extract and a Citrus aurantium extract as active ingredients. A method of the present disclosure can be used for the preparation of an agent for treating depression and anxiety, which are stress diseases, with few side effects because of the use of a natural material, and a health functional food having effects of alleviating depression, anxiety and fatigue, which are stress diseases.
Abstract: Provided herein are compositions for treating a disorder or a disease associated with or characterized by neuro-inflammation, neuro-apoptosis, or neuro-oxidative damage in a subject, pharmaceutical compositions comprising the compositions and pharmaceutically acceptable excipients, and pharmaceutical formulations comprising the compositions. Provided also herein are methods of treating a disorder or a disease associated with or characterized by neuro-inflammation, neuro-apoptosis, or neuro-oxidative damage in a subject, and methods of regulating inflammation, antioxidant enzymes, and apoptosis in a subject having a disorder or a disease associated with or characterized by neuro-inflammation, neuro-apoptosis, or neuro-oxidative damage.
Abstract: The invention concerns a composition for lowering the glycemic index comprising, or consisting of an alcoholic extract of cinnamon in an amount of at least 10% by weight compared to the total weight of the composition, and optionally a carrier, a food composition comprising a composition for lowering the glycemic index in an amount ranging from 0.1% to 5% by weight compared to the total weight of the food composition, the use of a composition for lowering the glycemic index or of a food composition as a glycemic index lowering agent.
Abstract: An herbal remedy to asthma comprising a weighed proportional mixture of Sunnut honey and powder of ground seeds of Solarium dubium. Separation and isolation of active compounds from the methanolic extract of combination was carried out using bioassay-guided fractionation. The in-vivo experiments were implemented to assess the toxicological study of the crude and methanolic extracts of the combination, honey and the seeds. The results revealed that there is no acute or sub-chronic toxicity displayed by the different concentrations of the extracts. The method of Carrageenan induced paw edema in Wister Rats was done to evaluate the anti-inflammatory effects of aqueous crude extract of S. dubium seeds, honey and combination. The results showed that all ingredients were found to have a significant anti inflammatory activity on paw edema volume.
Abstract: The invention belongs to the field of medicine, involving new uses of Paliurus ramosissimus (Lour.) Poir. and its extract, in particular the use of Paliurus ramosissimus (Lour.) Poir. and its extract in preparation of drugs with anti-fibrotic, anti-fungal, and anti-tumor activities, for the treatment of oral and digestive tract inflammation or (and) ulcer-related diseases, or with bi-directional immunomodulatory effects.
Type:
Grant
Filed:
December 14, 2018
Date of Patent:
April 27, 2021
Assignee:
SICHUAN ACADEMY OF CHINESE MEDICINE SCIENCES
Inventors:
Chaoqun Xu, Dongxiao Li, Guangming Shu, Jia Ruan, Yan Zhan, Lei Tan
Abstract: Compositions for treating erectile dysfunction (“ED”), including age related erectile dysfunction (ARED), comprise in a preferred embodiment ginger and an amino acid. Preferably the amino acid is L-arginine and/or L-citrulline. Additionally, the compositions may comprise guarana (Paullinia cupana), Muira puama cortex Magnoliae officinalis (CMO) and/or Fructus aurantil immaturus (FAI). The compositions of the present inventions are administered in a pharmaceutically effective amount to treat erectile dysfunction. Essential ingredients in formulations of the present inventions for treatment of ED and ARED are ginger (or ginger derivative) and L-citrulline or L-arginine. A daily dosage of at least about 250 mg ginger and at least about 400 mg L-citrulline or L-arginine for a sufficient period of time will result in improved IIEF scores in a substantial number of patients.
Type:
Grant
Filed:
June 18, 2019
Date of Patent:
April 13, 2021
Assignee:
K.L.R.M., LLC
Inventors:
Jacob Rajfer, Mauro Milchteim, Floyd Alexander Katske
Abstract: A botanical extract for use in skin care, wherein the botanical extract is at least an extract from the testa of the seed of Anacardium occidentale L.
Abstract: The present invention relates to a composition for, inter alia, preventing or treating a climacteric disease, or preventing or improving a climacteric skin symptom comprising a soybean extract comprising coumestrol as an active ingredient, and more specifically relates to a composition for, inter alia, preventing or treating a climacteric disease, or preventing or improving a climacteric skin symptom comprising a germinated and fermented soybean extract comprising coumestrol as an active ingredient.
Type:
Grant
Filed:
May 25, 2018
Date of Patent:
March 30, 2021
Assignee:
AMOREPACIFIC CORPORATION
Inventors:
Hyun Jung Shin, Hyun Woo Jeong, Ji Hae Lee, Dae Jin Min, Dae Bang Seo, Sang Jun Lee
Abstract: The present invention relates to a pharmaceutical composition for preventing or treating alpha-herpesvirus infection comprising an Elaeocarpus sylvestris extract or a fraction thereof as an active ingredient, and can effectively prevent, treat or alleviate an alpha-herpesvirus and diseases caused thereby, such as herpes, encephalitis, genital herpes, chicken pox, or herpes zoster.
Abstract: Polar extracts of Erodium plants are disclosed as well as pharmaceutical compositions and cosmetic compositions comprising same. Uses of the polar extracts are also disclosed.
Type:
Grant
Filed:
March 31, 2016
Date of Patent:
March 30, 2021
Assignees:
The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Voleaui Center), The Economic Company For The Development Of Ramat Hanegev Ltd.
Inventors:
Hinanit Koltai, Yoram Kapulnik, Marcelo Fridlender, Einav Mayzlish Gati, Nasser Ahmed, Shemer Ben Zion
Abstract: Method for maintaining and improving reduced kidney function and improving quality of life in patients suffering from diseases that result in reduced renal function comprising administering RENDAYL™ in combination with standard of care treatment.
Abstract: The present invention relates to bioactive fractions (ingredients) derived from fruit juices. The bioactive fractions are either free of or substantially free of patulin and protein. Further, the bioactive fractions have antioxidant, free radical scavenging, moisturizing and buffering properties. The present invention also relates to a method for isolating bioactive fractions that are derived from fruit juices and are free or substantially free of protein and patulin. The present invention also relates to a method for preparing a bioactive fractions derived from fruit juices that are stabilized and are either free of or substantially free of patulin and protein.
Type:
Grant
Filed:
April 5, 2019
Date of Patent:
March 23, 2021
Assignee:
ISP INVESTMENTS LLC
Inventors:
Michael Koganov, Olga Dueva-Koganov, Artyom Duev, Steven Micceri
Abstract: The present disclosure discloses an anti-inflammatory composition comprising turmeric alcohol extract, beta caryophyllene, 3-o-acetyl-11-keto-beta-boswellic acid, extract obtained from Kaempferia galanga and turmeric water extract. The present disclosure also describes a process of preparing the composition containing these extracts, which mainly involves extracting curcumin alcohol extract from turmeric, extracting gum resin from Boswellia serrata, AKBA is isolated from the extracted gum resin and complexed with phospholipid, beta-caryophyllene is isolated from Piper nigrum by steam distillation and subjected to fractionation for purification, flavonoids rich aqueous extract is extracted from Kaempferia galanga and turmeric water extract powder is obtained from Curcuma longa. The extracts are combined together to form a complete natural matrix, homogenized and subjected to spray drying to obtain a uniform mixture in a powdered form.
Type:
Grant
Filed:
August 19, 2017
Date of Patent:
March 23, 2021
Assignee:
AUREA BIOLABS PRIVATE LIMITED
Inventors:
Sreeraj Gopi, Karthik Varma Ayiranazhi Covilakam, Robin George