Abstract: Disclosed are devices and methods for treatment of eye disease. The suprachoroidal space is used as a conduit within which to place a drug delivery device. One such drug delivery device may be a tube, wicking element, bioabsorbable polymer structure, or other configuration of drug delivery substrate. The delivery device may include a port on the proximal end to assist in repeat injection, and may include a reservoir to either collect flow from the aqueous to concentrate it along the length of the device, or act as a repository for injected agent.
Abstract: A disposable syringe for use in a needleless injector includes a tubular body with an open rear end, a closed front end containing an injection orifice, a chamber in the body for receiving a liquid and a plunger slidable in the chamber for pushing the liquid out of the orifice. A tip is provided on the inner end of the plunger for separation from the remainder of the plunger to block the orifice when the plunger is retracted after an injection, whereby the syringe cannot be re-used.
Abstract: An alert device for use with an intravenous drip, comprises two induction ends and a control unit. The control unit comprises a circuit module, an alarm module and a power module. The two induction ends are located on a pipe of the intravenous drip and are contacting with an injection solution inside the pipe. The two induction ends are electrically connected to the control unit by wires. The circuit module detects the induction ends to determine whether the induction ends are in an open-loop status or not. The circuit module connects to the alarm module. The power module supplies power for the control unit. The induction ends uses the injection solution as a conducting means to form an electrically closed loop; when the induction ends do not contact with the injection solution, the induction ends become an open-loop, and thus the alarm module generates alarm signals.
Abstract: A pressure detection device of a liquid flow route is provided which detects a pressure of an arterial blood circuit consisting of a flexible tube, a portion of which is connected to a peristaltically-actuated tube that can cause an internal liquid to flow by being compressed in a radial direction and being peristaltically actuated in a longitudinal direction in a roller of a blood pump, and which enables a predetermined liquid to be circulated. The pressure detection device includes a load sensor that detects radial displacement of the peristaltically-actuated tube.
Abstract: An assembly of a drug delivery system, comprising: a first component; a second component which is configured to move linearly with respect to the first component; and, a resistance element configured to resist linear movement during transport of the first component with respect to the second component in a closed transport configuration but which is adapted to be overcome during nominal operation of the drug delivery system.
Type:
Grant
Filed:
April 30, 2013
Date of Patent:
May 23, 2017
Assignee:
MEDIMOP MEDICAL PROJECTS LTD.
Inventors:
Oz Cabiri, Reuven Y. Filman, Yossi Bar-El
Abstract: The present invention is directed to an automatic reconstitution drug delivery device. The inventive device effects simple and automatic reconstitution of a dry drug. To effect reconstitution, a user displaces a release button which causes first and second chambers of a drug cartridge to communicate, resulting in automatic mixing of a diluent and dry drug to effect reconstitution of the dry drug. The user then simply sets the dose volume using a dose-setting mechanism, and administers the injection in a manner typical of self-injection drug delivery devices. Whole or partial automatic priming can be also achieved by the device.
Abstract: Medical devices such as catheters can include structure or provision that permit a physician or other health care professional to adjust the stiffness of at least a portion of the medical device. In some instances, the medical device may be adjusted prior to inserting the medical device into a patient. In some cases, the medical device may be adjusted while in use within the patient.
Type:
Grant
Filed:
August 26, 2014
Date of Patent:
May 16, 2017
Assignee:
Boston Scientific Scimed Inc.
Inventors:
Daniel J. Gregorich, Soo-Young Yoon, Michael P. Meyer, Liza J. Davis
Abstract: A stopper includes a main body portion defining an open rearward end configured to receive the plunger rod, an engagement portion provided along an inner circumference of the main body portion configured to engage at least a top portion of the plunger rod, a closed front end forming a flexible roof, and a first perimetrical skirt extending around an outer circumference of the main body portion toward the closed front end of the main body portion. When fluid pressure is increased inside the syringe barrel during an injection, the flexible roof expands in a radial direction toward an inner wall of the syringe barrel, the first perimetrical skirt is forced against the inner wall of the syringe barrel, and an engagement between the plunger rod and the engagement portion forces the main body portion to expand in the radial direction toward the inner wall of the syringe barrel.
Type:
Grant
Filed:
March 28, 2012
Date of Patent:
May 9, 2017
Assignee:
Becton, Dickinson and Company
Inventors:
Milan Ivosevic, Girum Yemane Tekeste, Andrew Wong, Michael Vincent Quinn, Andrzej Baranski
Abstract: Systems and methods for epicardial electrophysiology and other procedures are provided in which the location of an access needle may be inferred according to the detection of different pressure frequencies in separate organs, or different locations, in the body of a subject. Methods may include inserting a needle including a first sensor into a body of a subject, and receiving pressure frequency information from the first sensor. A second sensor may be used to provide cardiac waveform information of the subject. A current location of the needle may be distinguished from another location based on an algorithm including the pressure frequency information and the cardiac waveform information.
Type:
Grant
Filed:
May 4, 2012
Date of Patent:
May 9, 2017
Assignee:
University of Virginia Patent Foundation
Inventors:
Srijoy Mahapatra, George T. Gillies, Jason Tucker-Schwartz
Abstract: A compressor has suction reed valves each of which includes a fixation portion fixed to the valve base plate, a basal portion that extends from the fixation portion and is separable from the plate, and a valve flap extending from the basal portion toward the distal end to selectively open and close the suction port. Each suction port has a shape elongated in the width direction, which is orthogonal to the longitudinal direction. The width of the basal portion is greater than that of the suction port. Each valve flap includes an opening-closing portion facing the corresponding suction port and stoppers, which project from the ends in the width direction. The side edges in the width direction are continuous from the stoppers to the basal portion to gradually approach the suction port. The cylinder block has pairs of recessed retainers. The stoppers contact the retainers.
Abstract: Systems, devices and methods for eluting an agent at a treatment site are disclosed. The devices include an expandable frame and at least one membrane. The membrane may carry an agent to elute at the treatment site. The membrane may allow blood flow at the treatment site during agent delivery.
Type:
Grant
Filed:
November 25, 2015
Date of Patent:
May 2, 2017
Assignee:
Abbott Cardiovascular Systems Inc.
Inventors:
Paul M. Consigny, William E. Webler, Gustavo D. Cipolla, Gordon S. Stewart, Benjamyn Serna, Daniel L. Cox
Abstract: In the generic exhaust-gas turbocharger, the turbine-side and compressor-side radial bearing bush are of identical design. A more compact bearing space, and improvements in acoustics and rotor dynamics, are achieved by providing different bearings on the turbine and compressor sides.
Abstract: A medical device control handle or catheter includes deflection assembly and at least one of the following: a disk actuator, a lever actuator and a ring actuator for actuating additional puller wires in manipulation of multiple features of the medical device or catheter independently of each other. The disk actuator has a common rotational axis with but is rotationally independent of the deflection assembly. The lever actuator has a separate rotational axis. The ring is mounted outside of the control handle and rotatable relative to the control handle to actuate another puller wire for manipulating another feature of the catheter. Each of the disk, lever and ring actuators are of a design that allows existing control handles and catheters to be readily modified to include these actuators.
Type:
Grant
Filed:
September 9, 2015
Date of Patent:
April 25, 2017
Assignee:
BIOSENSE WEBSTER (ISRAEL), LTD.
Inventors:
Dennis C. Caples, Keshava Datta, Rajesh Pendekanti
Abstract: Various methods employing transvascular access devices are described, including a method of placing a central catheter in a peripheral vein in an arm of a patient; a method of providing percutaneous access to the heart of a patient; a method of clearing a clotted arteriovenous dialysis graft; a method of creating multiple access points into a single blood vessel; a method of creating an AV fistula in a patient; and a method of providing a bypass to a blockage in a popliteal artery in a patient.
Abstract: A resettable dosing mechanism comprises a dose button and a dial grip operatively coupled to the dose button. A spindle acts on a bung of a cartridge and a driver is operatively coupled between the dose button and the spindle. During an injection of the dose, the dose button moves in an axial direction to cause the spindle to administer the dose. During resetting of the dose setting mechanism, the spindle is retracted back into the dose setting mechanism.
Abstract: An electric pump includes a housing and a motor unit having a stator disposed in the housing. A rotor is rotatably disposed on the stator and a rotating shaft is inserted in and passing through the rotor. A pump comprises an inner rotor coupled to one end of the rotating shaft and an outer rotor, and the pump has an inserting recess for receiving the pump.
Abstract: A syringe carpule for storing, transporting and in situ mixing of a local anesthetic, such as lidocaine, and a buffer, such as sodium bicarbonate, and delivery of buffered anesthetic solution comprises a hollow tubular body received within the frame of a carpule syringe, at least one axially movable plunger within the body and configured to be engaged and moved by a rod of the carpule syringe, a seal pierced by a rear portion of a needle coupled to the carpule syringe, a first chamber within the body filled with anesthetic solution during storing and transport, a second chamber defined within the body filled with buffering solution during storing and transport; and a breachable separating member between the first and second chamber configured to be removed by a piercing-mixing unit for in situ mixing of the buffering and the anesthetic solutions allowing for delivery of a buffered anesthetic solution.
Abstract: An auto-injector for injecting a fluid medicament into a patient from a pre-filled syringe requires a disposable cassette that is selectively engageable with the reusable injector. The syringe is latched onto the cassette, and the cassette is then engaged with the injector. Activation of the injector causes a first motor to move the syringe so its needle is extended from a concealed position inside the cassette for injection of the medicament. A second motor on the injector is then activated to expel fluid medicament from the syringe. Then, the first motor is again activated to withdraw the syringe into the cassette for disposal of the cassette/syringe after an injection.
Type:
Grant
Filed:
October 10, 2011
Date of Patent:
April 11, 2017
Assignee:
AVANT MEDICAL CORPORATION
Inventors:
John B. Slate, Richard J. Koerner, Corey M. Magers, Michael W. Burk
Abstract: An infusion set component of a fluid infusion device and/or a fluid infusion port component for delivery of fluid to a patient is compatible with a cooperating fluid channel module. The fluid channel module includes a body section having coupling features to mate with a base of the component. The fluid channel module also includes an interior fluid flow channel formed within the body section to receive fluid from the fluid infusion device and/or from a syringe or pen delivery device. The fluid channel module also includes a conduit having a first end in fluid communication with the interior fluid flow channel, and having a second end to deliver the fluid to the patient.
Type:
Grant
Filed:
May 3, 2012
Date of Patent:
April 4, 2017
Assignee:
MEDTRONIC MINIMED, INC.
Inventors:
David Christopher Antonio, Sumona Nag Adhya, Jose J. Ruelas, Eric Allan Larson
Abstract: Embodiments provide apparatus and methods for delivering liquid form medication within the body wherein the medication is stored in solid form and then mixed with a liquid in an apparatus implanted within the body. One embodiment provides an implantable apparatus for in vivo delivery of medication comprising a housing including a reservoir, a store of solid form medication (SSM) and a pump. An SSM element is added to the reservoir along with fluid to form a medication solution comprising at least one drug. The medication solution is then delivered to a delivery site using a pumping means to pump solution from the reservoir through a delivery member such as catheter to a delivery site. Embodiments of the invention are particularly useful for delivering medication to a patient to treat a medical condition over an extended period of time without requiring the patient to take external medication.