Patents Examined by Thomas A. Waltz
  • Patent number: 4367239
    Abstract: The present invention relates to novel aminoalkyl substituted nitrosourea derivatives as well as their acid addition salts with pharmaceutically acceptable acids showing pronounced antineoplastic effectiveness in animal experiments.The novel compounds of the present invention may be represented by the following formula: ##STR1## wherein X and Y are the same or different, and are selected from the group consisting of a phenyl group and a cyclohexyl group, said phenyl and cyclohexyl groups being optionally substituted with one or two substituents selected from a halogen atom, a lower alkyl group having from one to four carbon atoms inclusive, a trifluore methyl group, a cyano group, a phenyl group, a cyclohexyl group and a lower alkyloxy group having from one to four carbon atoms inclusive."Alkylene" is an alkylene group, branched or unbranched, having from one to four carbon atoms inclusive, and R.sup.1 and R.sup.
    Type: Grant
    Filed: September 29, 1980
    Date of Patent: January 4, 1983
    Assignee: Kefalas A/S
    Inventors: Peter Bregnedal, Jorn Buus
  • Patent number: 4367345
    Abstract: A process for producing tolylthiourea having high purity comprises reacting toluidine with a thiocyanate and a mineral acid in the presence of an organic solvent and water.
    Type: Grant
    Filed: April 23, 1981
    Date of Patent: January 4, 1983
    Assignee: Ihara Chemical Industry Co., Ltd.
    Inventors: Yutaka Ohishi, Yoshiki Nakayama, Chihiro Yazawa
  • Patent number: 4366151
    Abstract: Reaction of monohydroxy-fatty acids of the formulaCH.sub.3 --(CH.sub.2).sub.m --CHOH--(CH.sub.2).sub.n --COOHwhere m is an integer from 4 to 9 and n is an integer from 6 to 11, with from 12 to 20 moles of ethylene oxide, the products thus obtained, and their use as solubilizers.
    Type: Grant
    Filed: August 12, 1981
    Date of Patent: December 28, 1982
    Assignee: BASF Aktiengesellschaft
    Inventors: Knut Oppenlaender, Heinz Krapf, Siegfried Lang
  • Patent number: 4366100
    Abstract: Completely biodegradable, toxicologically innocuous, oxidation-resistant, flavorless and odorless, light-colored, homogeneous liquid ester mixtures with low turbidity points, low evaporation losses at elevated temperatures, and viscosities and densities adjustable as desired, comprising the products of esterification of 1 mol of glycerin with from 1.4 to 2.8 mols of a saturated aliphatic monocarboxylic acid having from 6 to 10 carbon atoms, or mixtures thereof, and from 0.1 to 0.8 mol of a saturated aliphatic dicarboxylic acid, or mixtures or anhydrides thereof, said ester mixtures having hydroxyl numbers ranging from 5 to 20 and an acid number of less than 5.
    Type: Grant
    Filed: July 2, 1981
    Date of Patent: December 28, 1982
    Assignee: Dynamit Nobel AG
    Inventors: Sasanka S. Naskar, Reinhard Pass
  • Patent number: 4366317
    Abstract: This invention provides an improved process for synthesizing carboxamides which involves reacting 3-p-menthyl halide with magnesium to form 3-p-menthylmagnesium halide Grignard reagent, and reacting the Grignard reagent with hydrocarbyl isocyanate at a temperature below about -20.degree. C. to form N-hydrocarbyl-p-menthane-3-carboxamide product.The product comprises a mixture of geometric isomers in which the 3-p-menthyl:3-p-neomenthyl weight ratio is at least 4:1 and can be as high as 9:1 under optimal conditions.This invention also provides a novel process for producing acylurea compounds such as N-(3-p-menthylcarbonyl)-N-t-butyl-N'-t-butylurea.
    Type: Grant
    Filed: June 22, 1981
    Date of Patent: December 28, 1982
    Assignee: Philip Morris Incorporated
    Inventors: Stephen A. Haut, Roger A. Comes
  • Patent number: 4365090
    Abstract: In a process for producing acrylamide by hydrating acrylonitrile in the presence of a copper-based catalyst, the reaction is carried out in the presence of 30 to 10,000 ppm of acetone in the reaction solution. According to this process, the activity of the copper-based catalyst is maintained and the economic advantage of acrylamide production is enhanced.
    Type: Grant
    Filed: May 18, 1981
    Date of Patent: December 21, 1982
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventor: Shiro Asano
  • Patent number: 4364921
    Abstract: New triiodinated isophthalic acid diamides of the formula ##STR1## wherein the amide residues --CO--N.R.sub.1 R.sub.2 and --CO--N.R.sub.3 R.sub.4 are different from each other andR.sub.1 is hydrogen or C.sub.1-6 alkyl,R.sub.2 is mono- or polyhydroxyalkyl,R.sub.3 is hydrogen or C.sub.1-6 alkyl,R.sub.4 is mono- or polyhydroxylalkyl,R.sub.5 is C.sub.1-6 alkyl or mono- or polyhydroxy-C.sub.1-6 -alkyl or C.sub.1-3 -alkoxy-C.sub.1-3 -alkyl, andR.sub.6 is hydrogen, C.sub.1-6 alkyl or mono- or polyhydroxyalkyl provide superior nonionic X-ray contrast media.
    Type: Grant
    Filed: March 6, 1980
    Date of Patent: December 21, 1982
    Assignee: Schering, Aktiengesellschaft
    Inventors: Ulrich Speck, Peter Blaszkiewicz, Dieter Seidelmann, Erich Klieger
  • Patent number: 4363754
    Abstract: 4(5)-acetyl-9,9-dimethyltricyclo-[4,4,0,1.sup.8,10 ]-undec-1-ene having the formula ##STR1## its synthesis, its use as a perfumery agent and as an olfactant component in perfumery compositions and as an odorant for technical products.
    Type: Grant
    Filed: November 2, 1981
    Date of Patent: December 14, 1982
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Jens Conrad, Klaus Bruns, Horst Upadek
  • Patent number: 4361438
    Abstract: Compounds having the formula ##STR1## in which X and Y are halogen; R is cyano, halogen, thio-C.sub.1 -C.sub.4 alkyl, phenyl, pyridyl, hydroxy, or OR.sub.1 ; R.sub.1 is C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 mono- or di-alkylcarbamyl, C.sub.2 -C.sub.6 alkoxyalkyl, phenylcarbamyl, C.sub.1 -C.sub.6 alkanoyl or C.sub.1 -C.sub.6 haloalkanoyl; and n is: (a) 1 or 2 if R is thioalkyl, cyano or phenyl; and (b) 2 if R is otherwise as defined, are herbicides.
    Type: Grant
    Filed: January 21, 1981
    Date of Patent: November 30, 1982
    Assignee: Stauffer Chemical Company
    Inventor: Raymond A. Felix
  • Patent number: 4359596
    Abstract: Liquid salts such as quaternary phosphonium and ammonium salts of halides, acids, or more complex anions can be utilized to extract aromatics from mixed aliphatic/aromatic hydrocarbon feeds such as isomerization process feed streams, cat naphthas, lube stocks, and the like. Such salts show the required solubilities in various solvents to exhibit a distinct selectivity advantage over more commonly used extraction solvents such as sulfolane in the extraction of benzene and other aromatics from heptane and other aliphatic feedstreams.
    Type: Grant
    Filed: August 3, 1981
    Date of Patent: November 16, 1982
    Assignee: Exxon Research and Engineering Co.
    Inventors: Kent A. Howard, Howard L. Mitchell, Robert H. Waghorne
  • Patent number: 4358611
    Abstract: 2-Phenylsemicarbazides are prepared by a multi-step process involving:(a) treating a phenylhydrazine, or salt thereof, with a chloroformate;(b) adding phosgene;(c) treating the resulting product with an amine; and(d) hydrolyzing the resulting acylated semicarbazide. The reaction can proceed through a .DELTA..sup.2 -1,3,4-oxadiazolin-5-one intermediate formed with heating in step (b). Certain of the products are novel compounds.
    Type: Grant
    Filed: January 9, 1978
    Date of Patent: November 9, 1982
    Assignee: Shell Oil Company
    Inventor: Kurt H. G. Pilgram
  • Patent number: 4358309
    Abstract: There are provided novel urea derivatives of the general formula ##STR1## wherein X, n, A and R are defined in the description; processes for preparing the derivatives and herbicidal composition containing as active ingredient the derivative. The derivatives have highly selective herbicidal activities.
    Type: Grant
    Filed: March 26, 1981
    Date of Patent: November 9, 1982
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Tetsuo Takematsu, Masaki Takeuchi, Masanori Okada, Hiroshi Sugiyama, Yasushi Murakami
  • Patent number: 4357476
    Abstract: New nonadienylamines, nonatrienylamines and nonylamines are described, as well as a new process for their manufacture by reacting a 1,3-diolefine with a Schiff's base in the presence of certain nickel catalysts. The new compounds are suitable for combating micro-organisms, for example in the protection of materials.
    Type: Grant
    Filed: November 22, 1978
    Date of Patent: November 2, 1982
    Assignee: Ciba Geigy Corporation, N.Y.
    Inventors: Dieter Reinchr, Bernard Hugelin, Eduard Troxler
  • Patent number: 4356097
    Abstract: Engine crankcase lubricating oil containing a dihydrocarbyl hydrocarbylphosphonate (e.g. diethyl octadecylphosphonate) exhibits reduced friction which results in an increase in gasoline mileage thus conserving energy.
    Type: Grant
    Filed: February 12, 1979
    Date of Patent: October 26, 1982
    Assignee: Edwin Cooper, Inc.
    Inventor: Andrew G. Papay
  • Patent number: 4356335
    Abstract: Novel trifluoropropyl-substituted aryl- or aralkylbenzenes of the formula: ##STR1## wherein R is a not-substituted or ring-substituted phenyl-, benzyl-, phenethyl- or alpha-methylbenzyl group by one 3,3,3-trifluoropropyl group, and n is an integer of 1,2 or 3, provided that the total number of 3,3,3-trifluoropropyl group of the above-mentioned trifluoropropyl-substituted aryl- or aralkylbenzene is at most 3, and a process for the production thereof are disclosed.
    Type: Grant
    Filed: February 12, 1981
    Date of Patent: October 26, 1982
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Yoshiro Kobayashi, Itsumaro Kumadaki, Masaaki Takahashi, Takashi Yamauchi
  • Patent number: 4356322
    Abstract: A series of novel derivatives of phenoxyalkanolamine of the general formula: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are the same or different and are hydrogen, alkyl of 1 to 2 carbon atoms, methoxy, halogen, nitro, amino or acylamino residues, and the salts thereof, are described, as are methods for their synthesis. The compounds are highly active .beta..sub.1 -specific sympathicomimetics with a partially antagonistic component.
    Type: Grant
    Filed: March 24, 1980
    Date of Patent: October 26, 1982
    Assignee: Veb Arzneimittelwerk Dresden
    Inventors: Dieter Lehmann, Klaus Femmer, Gottfried Faust
  • Patent number: 4355178
    Abstract: The invention relates to a process for the preparation of acyl ureas of formula (I) ##STR1## wherein R.sub.1 and R.sub.2 are the same of different and each is halogen atom, preferably fluorine or chlorine atom, andR.sub.3 is a substituted aryl group.The compounds of the invention can be prepared by reacting an urea of formula (II):R.sub.3 NHCONH.sub.2 (II)wherein R.sub.3 is as defined above, with an acid chloride of formula (III): ##STR2## wherein R.sub.1 and R.sub.2 are as defined above, in an inert organic solvent at a temperature of from 20.degree. C. to 100.degree. C.
    Type: Grant
    Filed: October 17, 1980
    Date of Patent: October 19, 1982
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
    Inventors: Laszio Toke, Istvan Bitter, Eva Karpati nee Adam, Todor Pfliegel
  • Patent number: 4355163
    Abstract: Dyestuffs of the formula ##STR1## wherein X, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 have the meaning indicated in the description,and their use for dyeing and printing materials containing hydroxyl groups or amide groups, such as textile fibres, filaments and fabrics of wool, silk or synthetic polyamide or polyurethane fibres, and for dyeing and printing natural or regenerated cellulose with dyeings and prints which are fast to washing.
    Type: Grant
    Filed: November 20, 1979
    Date of Patent: October 19, 1982
    Assignee: Bayer Aktiengesellschaft
    Inventors: Klaus von Oertzen, Wolfgang Harms, Klaus Wunderlich
  • Patent number: 4355169
    Abstract: This invention is concerned with certain 3-(thiazolidin-2'-yl)-substituted phenyl sulfonamides which find utility as intermediates in the preparation of photographic image dye-providing materials.
    Type: Grant
    Filed: March 2, 1981
    Date of Patent: October 19, 1982
    Assignee: Polaroid Corporation
    Inventors: Donald A. McGowan, Frank A. Meneghini
  • Patent number: 4353842
    Abstract: A novel method of treating gastrointestinal, spasmolytic and ulcerogenic disorders by the administration of amidinoureas is disclosed.
    Type: Grant
    Filed: February 5, 1980
    Date of Patent: October 12, 1982
    Assignee: William H. Rorer, Inc.
    Inventors: Julius Diamond, George H. Douglas