Patents Examined by Thor Nielsen
  • Patent number: 9961899
    Abstract: Provided herein are aqueous suspension concentrate compositions comprising biologically active 3,5-disubstituted-1,2,4-oxadiazoles or salts thereof that are useful, for example, in the control of nematodes. Nematodes are active, flexible, elongate organisms that live on moist surfaces or in liquid environments, including films of water within soil and moist tissues within other organisms. Many species of nematodes have evolved to be very successful parasites of plants and animals and, as a result, are responsible for significant economic losses in agriculture and livestock.
    Type: Grant
    Filed: December 4, 2013
    Date of Patent: May 8, 2018
    Assignee: Monsanto Technology LLC
    Inventors: Yiwei Ding, Shaun Raj Selness, Urszula J. Slomczynska
  • Patent number: 9955689
    Abstract: The present invention provides a method for promoting plant growth, which comprises treating a plant with at least one compound selected from a group consisting of a compound represented by the following Formula (1): and an agriculturally acceptable salt thereof, provided that a method for promoting plant growth which comprises treating plants with a compound corresponding to any one of the following (1) to (5) and an agriculturally acceptable salt thereof is excluded: (1) 4-(Trifluoromethyl)benzo[b]thiophene-2-carboxylic acid, (2) 5-(Trifluoromethyl)benzo[b]thiophene-2-carboxylic acid, (3) 6-(Trifluoromethyl)benzo[b]thiophene-2-carboxylic acid, (4) 7-(Trifluoromethyl)benzo[b]thiophene-2-carboxylic acid, and (5) Benzo[b]thiophene-2-carboxylic acid.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: May 1, 2018
    Assignee: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventors: Fujio Mukumoto, Hiroaki Tamaki, Shintaro Kusaka, Mitsuhiko Iwakoshi
  • Patent number: 9956177
    Abstract: A method of making a sustained release microsphere formulation, wherein the release rate of a bioactive ingredient is manipulated by controlling the crystallinity of said bioactive ingredient, includes the steps of combining the active ingredient and an encapsulating polymer in at least one solvent, or mixtures thereof, to form a dispersed phase and processing the dispersed phase without filtering, filtering the combined dispersed phase with a hydrophobic or a hydrophilic filter, or filtering the active ingredient and encapsulating polymer individually with a hydrophobic or hydrophilic filter before combining them to form the dispersed phase. The dispersed phase is then combined with a continuous phase to form the microsphere formulation.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: May 1, 2018
    Assignee: OAKWOOD LABORATORIES LLC
    Inventors: Tracy Richey, Bagavathikanun Chithambara Thanoo
  • Patent number: 9943079
    Abstract: Modified mineral-based fillers with enhanced retention of at least one active ingredient and/or enhanced antimicrobial capabilities are described. The materials comprise at least one mineral-based filler subjected to at least one modification process, which may be either a cationic modification process, a surface adsorption process, a surface retention process, or a combination thereof, with at least one active ingredient, followed by at least one thermal treatment. The at least one active ingredient may be a metal substance or other biocide, fungicide, mildewcide, antibiotic, insecticide, preservative, or antimicrobial agent. Methods for enhancing the antimicrobial activity of products in applications such as polymers, clothing, surgical equipment, coatings, and paints are also described.
    Type: Grant
    Filed: October 27, 2008
    Date of Patent: April 17, 2018
    Assignee: Imerys Filtration Minerals, Inc.
    Inventor: Jie Lu
  • Patent number: 9937241
    Abstract: The present invention relates to novel therapies that utilize stabilized exogenous HSP70 for the treatment of disorders or conditions regulated by HSP70 through administration of degradation resistant formulations of HSP70. Furthermore, the present invention is directed to methods comprising the administration of stabilized exogenous HSP70 for use in the treatment of HSP70 related disorders or conditions, for example, for increased endurance or alleviating fatigue syndrome.
    Type: Grant
    Filed: October 13, 2012
    Date of Patent: April 10, 2018
    Assignee: ALTERNATIVE INNOVATIVE TECHNOLOGIES LLC
    Inventors: Sergei B Onikienko, Alex Nivorozhkin
  • Patent number: 9918480
    Abstract: Methods and compositions for controlling the growth of an invasive species by application of a composition comprised of a natural pesticide derived from a species to the invasive species, especially endocides. Disclosed herein are methods and compositions for controlling the growth of a first invasive species by application of a composition comprising a natural pesticide derived from a second invasive species to the first invasive species. In some embodiments, the invasive species is an invasive species with glands as the primary accumulation sites of autotoxic chemicals. The first and second invasive species may be the same or they may be different. In some embodiments, the natural pesticide may be an endocide. An endocide (endogenous biocide) is a biocide derived from an endogenous bioactive agent (e.g., a secondary metabolite) that does not cause apparent poison in normal growth of the producing species but will poison or inhibit and even eliminate the parent species when induced in producing species.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: March 20, 2018
    Assignee: Stephen F. Austin State University
    Inventors: Shiyou Li, Ping Wang, Wei Yuan, Zushang Su, Steven H. Bullard
  • Patent number: 9920001
    Abstract: The present invention is directed to a method for enhancing the rate of formation of the reaction products of a carboxylic acid and a urea having the formula: where R1, R2, R3 and R4 are the same or different and are selected from the group consisting of hydrogen, substituted and unsubstituted alkyl, allyl, vinyl and alkoxyl groups having from 1-6 carbon atoms, substituted and unsubstituted phenyl groups and the halides. The rate of formation is enhanced by adding acid to a solution including the carboxylic acid and the urea. Preferably, the reaction product of the present invention is N,N?-diformylurea or N,N?-diacetylurea. These reaction products, e.g., diformylurea, have been found to produce significantly improved growth in a variety of agricultural products when applied to the seed, to the surrounding soil or to the foliage of the emerging plant.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: March 20, 2018
    Assignee: Stoller Enterprises, Inc.
    Inventors: Jerry Stoller, Ritesh Sheth
  • Patent number: 9918933
    Abstract: The present invention discloses a medicine for treatment or adjuvant treatment of acquired immunodeficiency syndrome, a preparation method thereof and use methods thereof. The medicine comprises: lightyellow sophora root, glabrous greenbrier rhizome, bark of Chinese corktree, raw sessile stemona root, alumen, coptis root, cortex dictamni, chinaberry bark and root-bark, pangolin scales, amber, eucommia bark, tree peony bark, clematis root, common cnidium fruit, Chinese angelica, licorice root, common macrocarpium fruit, barbary wolfberry fruit, medicinal indianmulberry root, cherokee rose fruit, chinaroot greenbier rhizome, akebia fruit, milkvetch root, Japanese climbing fern spore, asiatic pennywort herb, mulberry leaf and frankincense.
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: March 20, 2018
    Inventor: Darong Liu
  • Patent number: 9913932
    Abstract: The present invention relates to methods for providing polymeric composites with bone forming, such as with osteogenic and/or osteoinductive and/or osteoconductive, properties. The present invention further relates to polymeric composites provided by the present method and the use of thereof for bone implants, or grafts, specifically the use thereof for orbital floor reconstruction. Specifically, the present invention relates to methods for providing a composite with bone forming properties, the method comprises the steps of: a) providing a liquid, or liquefied, polymeric composition of homopolymers or copolymers of 1,3-trimethylene carbonate (TMC); b) adding to said liquid, or liquefied, polymeric composition one or more agents with osteogenic and/or osteoinductive and/or osteoconductive properties thereby providing a dispersion of said agents in said liquid or liquefied polymeric composition; and c) crosslinking the product obtained, thereby providing a composite with bone forming properties.
    Type: Grant
    Filed: October 26, 2011
    Date of Patent: March 13, 2018
    Assignees: UNIVERSITEIT TWENTE, RUKSUNIVERSITEIT GRONINGEN, ACADEMISCH ZIEKENHUIS GRONINGEN
    Inventors: Dirk Wybe Grijpma, Rudolf Robert Maria Bos, Anne Cornelis Van Leeuwen
  • Patent number: 9901585
    Abstract: A pharmaceutical product or formulation, which comprises azelastine or a pharmaceutically acceptable salt, solvate or physiologically functional derivative thereof, and a steroid, or a pharmaceutical acceptable salt, solvate or physiologically functional derivative thereof, preferably the product or formulation being in a form suitable for nasal or ocular administration.
    Type: Grant
    Filed: March 15, 2016
    Date of Patent: February 27, 2018
    Assignee: Cipla Limited
    Inventors: Amar Lulla, Geena Malhotra
  • Patent number: 9894901
    Abstract: The present invention provides a method for promoting plant growth, which comprises treating a plant with a compound represented by the following Formula (1): provided that a method for promoting plant growth which comprises treating plants with a compound corresponding to any one of the following (1) to (8) is excluded: (1) Methyl 4-(trifluoromethyl)benzo[b]thiophene-2-carboxylate, (2) Methyl 5-(trifluoromethyl)benzo[b]thiophene-2-carboxylate, (3) Methyl 6-(trifluoromethyl)benzo[b]thiophene-2-carboxylate, (4) Methyl 7-(trifluoromethyl)benzo[b]thiophene-2-carboxylate, (5) Ethyl 4-(trifluoromethyl)benzo[b]thiophene-2-carboxylate, (6) Ethyl 5-(trifluoromethyl)benzo[b]thiophene-2-carboxylate, (7) Ethyl 6-(trifluoromethyl)benzo[b]thiophene-2-carboxylate, and (8) Ethyl 7-(trifluoromethyl)benzo[b]thiophene-2-carboxylate.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: February 20, 2018
    Assignee: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventors: Fujio Mukumoto, Hiroaki Tamaki, Shintaro Kusaka, Mitsuhiko Iwakoshi
  • Patent number: 9894899
    Abstract: A composition for treating a citrus tree having citrus greening disease includes an antibiotic, at least one micronutrient, water, and a bark penetrating surfactant like organosiloxane surfactant that is absorbed through the bark periderm and enters the lenticels of the tree. The antibiotic is one effective for treating a gram negative bacteria like HLB and is preferably tetracycline. The micronutrient can be zinc, manganese, or iron (and is preferably all three), and the zinc and manganese can be in sulfate form to serve as a bactericide. A pH adjusting compound such as ammonium sulfate can be included to adjust the pH of the water. A method of treating citrus greening disease using the composition includes the step of applying the composition onto the bark periderm of a citrus tree. The applying step results in the composition entering the vascular system of the citrus tree.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: February 20, 2018
    Inventor: Edward Schweighofer
  • Patent number: 9895453
    Abstract: An improved ultrasound gel adapted to have a shiny effect by adding glitter to an ultrasound gel, using a silver, reflective label and using a silver, reflective dispenser closure. This improved ultrasound gel is adapted to a pink lavendula lavender color by using the preservatives as coloring agents. Lavender essential oil is used as a perfume and preservative. The reflective glitter, reflective label, and reflective dispenser closure allow the ultrasonographer to better see the ultrasound gel and bottle in a darkened ultrasound room. The ultrasound gel is improved to have an aesthetic effect for the patient and healthcare provider by providing the combination of both a pink lavendula lavender color and a lavender scent.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: February 20, 2018
    Inventors: Mark Edward Fenzl, Tonya Suzanne Fenzl
  • Patent number: 9872493
    Abstract: The present invention provides a method for promoting plant growth, which comprises treating a plant with a compound represented by the following Formula (1): provided that a method for promoting plant growth which comprises treating plants with a compound corresponding to the following (1) or an agriculturally acceptable salt thereof are excluded, (1) benzo[b]thiophene-3-carboxylic acid. The method set forth in one of the above, the plant being soybeans. The method set forth in one of the above, the plant being cotton. A plant seed resulting from treatment with the compound of claim 1 containing an effective quantity of the compound indicated in formula (1). A composition for promoting plant growth and containing an inert component and the compound indicated in formula (1).
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: January 23, 2018
    Assignee: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventors: Fujio Mukumoto, Hiroaki Tamaki, Shintaro Kusaka, Mitsuhiko Iwakoshi
  • Patent number: 9868676
    Abstract: Aspects of the invention include compositions for enhancing pollination. Dry compositions according to certain embodiments include a carbon skeleton energy compound, macronutrients, a vitamin cofactor composition, micronutrients, an ionophore, and a source of extracted humate. Methods for using the dry compositions of the invention to enhance pollination are also described.
    Type: Grant
    Filed: March 5, 2014
    Date of Patent: January 16, 2018
    Inventor: Thomas T. Yamashita
  • Patent number: 9862922
    Abstract: A composition of matter is provided having bacillus subtilis, bacillus pumilus, bacillus coagulans, paenibacillus polymyxa, pseudomonas fluorescens, streptomycetes griseus, saccharomyces cerevisiae, trichoderma reesei, and trichoderma harzianum. The composition further includes dextrose, sucrose, brewer's yeast extract, humic acid, and kelp. Applying the composition in the proximity of the root system allows the composition to colonize the rhizosphere. The composition is generated by individually culturing the components, combining them with diatomaceous earth, and drying to encapsulate the components.
    Type: Grant
    Filed: September 19, 2016
    Date of Patent: January 9, 2018
    Assignees: PolyOrganic Technologies Corporation, Ultra-Grow Technologies, Inc.
    Inventors: Richard H. Maguire, Charles F. Bruno
  • Patent number: 9854811
    Abstract: The present invention includes compositions and methods for the treatment of plants against pathogens, elimination of insects and to increase the shelf-life of fruits and vegetables that includes coating the plant with undiluted aloe vera gel.
    Type: Grant
    Filed: December 18, 2012
    Date of Patent: January 2, 2018
    Assignee: Coats Agri Aloe, LLC
    Inventor: Billy C. Coats
  • Patent number: 9848542
    Abstract: The instant invention relates to methods for increasing or promoting microbial activity in soil selected for treatment.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: December 26, 2017
    Assignee: Oro Agri, Inc.
    Inventors: Erroll Melvyn Pullen, Melvin Donovan Pullen
  • Patent number: 9827191
    Abstract: Particles, compositions, and methods that aid particle transport in mucus are provided. The particles, compositions, and methods may be used, in some instances, for ophthalmic and/or other applications. In some embodiments, the compositions and methods may involve modifying the surface coatings of particles, such as particles of pharmaceutical agents that have a low aqueous solubility. Such compositions and methods can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for ophthalmic applications, and may be used for delivering pharmaceutical agents to the front of the eye and/or the back of the eye.
    Type: Grant
    Filed: November 2, 2013
    Date of Patent: November 28, 2017
    Assignee: The Johns Hopkins University
    Inventors: Alexey Popov, Elizabeth M. Enlow, Hongming Chen, James Bourassa
  • Patent number: 9820490
    Abstract: Presented herein are compositions comprising an antioxidant (i), a radiation manager (ii), and one or more of, a plant strengthener (iii), or a plant growth regulator (iv). Also presented herein are compositions comprising a plant strengthener (iii), and one or more of, an antioxidant (i), or a radiation manager comprising a polyoxyalkylene UV absorber (ii). Furthermore, methods of using the disclosed compositions are also provided.
    Type: Grant
    Filed: November 1, 2012
    Date of Patent: November 21, 2017
    Assignee: BAYER CROPSCIENCE LP
    Inventors: Richard Rees, James Rutledge, Mike Newnam