Abstract: An article in form of a strip for use in the oral cavity. The article includes a water insoluble delivery carrier comprising solid hydrophilic particles comprising at least one bleaching agent, wherein: (i) at least about 20 parts by weight of the solid hydrophilic particles dissolve in about 100 parts by weight of water, and/or (ii) wherein the solid hydrophilic particles increase by volume and/or weight by at least about 50% in water, and wherein the particles are embedded in the carrier.
Abstract: An oral care article in form of a strip for use in the oral cavity. The oral care article includes a hydrophobic delivery carrier comprising embedded solid hydrophilic particles comprising at least one bleaching agent, wherein at least about 20 parts by weight of the particles dissolve in about 100 parts by weight of water and/or the particles increase in volume and/or weight by at least about 50% upon contact with water.
Abstract: Described herein is a composition based on N-palmitoyl-ethanolamide and Rutin in co-micronized form. In particular, a composition includes a mixture of palmitoyl-ethanolamide (PEA) and Rutin in co-micronized form in which the PEA/Rutin ratio is between 10:1 and 1:1. Pharmaceutical formulations for the treatment of humans and animals are also described. The composition is useable for the treatment of diseases of arteries and arterioles.
Type:
Grant
Filed:
August 25, 2020
Date of Patent:
November 21, 2023
Assignee:
EPITECH GROUP S.P.A.
Inventors:
Francesco Della Valle, Maria Federica Della Valle, Gabriele Marcolongo, Salvatore Cuzzocrea, Vito Safina
Abstract: Disclosed herein are oral care compositions comprising: an orally acceptable vehicle comprising greater than about 50 wt. % water; and a preservative system comprising: benzyl alcohol, benzoic acid or a salt of benzoic acid; and an alkylene glycol. Methods of making and using these compositions are also described herein.
Type:
Grant
Filed:
January 17, 2020
Date of Patent:
October 17, 2023
Assignee:
Colgate-Palmolive Company
Inventors:
Sandra Pereira Ramos, Luiz Alberto Goncalves Filho, Fernanda Correa, Tatiana Cinquetti, Paulo Focassio
Abstract: An oral care composition comprising zinc phosphate, stannous fluoride and an organic acid buffer system, as well as methods of using the same.
Type:
Grant
Filed:
June 29, 2022
Date of Patent:
October 10, 2023
Assignee:
Colgate-Palmolive Company
Inventors:
Aarti Rege, Michael Prencipe, Madhuleena Bhadra
Abstract: A whitening toothpaste capable of effectively removing dental plaque and tartar includes cinnamic acid extract, osthole extract, Lactobacillus salivarius fermentation broth, glycerol, sorbitol, propylene glycol, silicon dioxide, sodium carboxymethyl cellulose, sodium lauryl sulfate, sodium fluoride, potassium fluoride or sodium monofluorophosphate and mint powder. In the present invention, the cinnamon and osthole extracting solutions and Lactobacillus salivarius are selected and used for bacteriostatic, tartar removing and whitening effects, fluoride additives are used for removing pigmentation, and dental plaque in a matched manner, and in combination with a toothpaste system, the toothpaste capable of effectively removing dental plaque and tartar is prepared.
Abstract: The invention relates to a dental cleaning wipe comprising a non-woven textile support impregnated with a dental hygiene composition containing mechanically-broken microcapsules, the content of which is released by breaking the wall, as well as controlled-release microcapsules, the content of which is released by permeation through the wall, the walls of said microcapsules being water-insoluble.
Abstract: An aqueous composition with a higher-than-neutral pH includes a significant amount of one or more surfactants and large amounts of osmotically active solutes. This composition, as well as an acidic counterpart and solid materials, can be used in a variety of applications such as wound care, oral care, medical equipment reprocessing, healthcare acquired infection and implant treatment.
Abstract: The invention relates to a composition comprising: i) one or more LDH-active anion materials comprising an LDH matrix intercalated with one or more active anions, and ii) a modifier system comprising a) one or more surfactants, in combination with b) one or more compounds having the generic formula MA, where M comprises one or more positively charged ions and A comprises one or more negatively charged counter ions.
Type:
Grant
Filed:
November 4, 2021
Date of Patent:
September 5, 2023
Assignee:
Oxford Pharmascience Limited
Inventors:
Elizabeth King, Marcelo Leonardo Bravo Cordero, Ann Taylor-Hutchinson
Abstract: The present invention relates to compositions for mineralizing a dental surface, in particular tooth enamel. Methods of mineralizing hypomineralized lesions (including subsurface lesions) in the tooth enamel caused by dental caries, dental corrosion and fluorosis are also provided. In particular, the invention relates to a method of mineralizing a dental surface or subsurface comprising contacting the dental surface or subsurface with a compound that is capable of increasing or maintaining the pH of a solution and a mineralizing agent.
Abstract: A chewable composition for teeth-whitening comprising a first region and a second region separated by a barrier layer; the first region comprising carbamide peroxide having water content of about 2% or less, a wetting agent (e.g., glycerin), an anhydrous chewing gum base having water content of about 1% or less, an anhydrous fruit acid, and one or more gum additives; and the second region comprising a chewable composition comprising a gum base, a source of bicarbonate ion, and one or more gum additives. A kit comprising separate chewable compositions corresponding to the first and second regions, and methods for whitening teeth using the chewable composition are also provided.
Abstract: A chewable composition for teeth-whitening comprising a first region and a second region separated by a barrier layer; the first region comprising carbamide peroxide having water content of about 2% or less, a wetting agent (e.g., glycerin), an anhydrous chewing gum base having water content of about 1% or less, an anhydrous fruit acid, and one or more gum additives; and the second region comprising a chewable composition comprising a gum base, a source of bicarbonate ion, and one or more gum additives. A kit comprising separate chewable compositions corresponding to the first and second regions, and methods for whitening teeth using the chewable composition are also provided.
Abstract: The disclosure is directed to processes and methods of reducing bloating and breakage of containers and packaging that house oral care compositions. Also contemplated are products and formulations that are produced or obtained from the processes and methods described herein.
Abstract: A toothpaste composition includes a structurant and a thickener, wherein the toothpaste composition has a predetermined viscosity and phase angle by using the structurant instead of reducing the content of a thickener, and thereby has an improved release property during use while maintaining a shape retention property of the toothpaste, and has an improved feeling of refreshment, flavor releasing power, cleaning power, and stain removal power. Further, provided is a toothpaste composition including a chelating agent containing phosphate and silica, wherein the chelating agent is supersaturated to precipitate phosphate to provide strong cleaning power, a whitening effect, a stain removal effect, and a crunchy sensation. Further, provided is a toothpaste composition including a peroxide, a thickener, and a spreading agent, wherein the peroxide and the thickener are separated from each other, providing excellent sense of use, stability, and a whitening effect in an anhydrous state.
Abstract: A mineralization agent, including, by weight: 5-50% of a film-forming protein, 5-40% of an amelogenin peptide, 5-30% of a water-soluble phosphate, 4-20% of a tris(2-carboxyethyl) phosphine hydrochloride, and 1-10% of a pH regulator. The film-forming protein is selected from the group consisting of lysozyme, bovine serum protein, insulin, ?-lactalbumin, or a mixture thereof.
Abstract: Disclosed herein are oral care compositions comprising a peroxide whitening complex in an amount to provide from 3.5% to 7% of hydrogen peroxide by weight of the composition, and a block copolymer of ethylene oxide and propylene oxide in an amount of from 40% to 60% by weight of the composition. Methods of making and using the dentifrices are also provided.
Abstract: A phosphorous compound such as STMP is used as a cross-linking agent while making a starch nanoparticle in an emulsion process. Negative charge of the nanoparticle is reduced or reversed by adding cations and/or cationizing the starch optionally while forming the nanoparticles. Anionic active agents, such as fluoride or fluorescein, are optionally incorporated into the nanoparticle during the formation process. For example, a fluoride salt can also be used, which promotes the crosslinking reaction while also providing fluoride in the nanoparticle. The retention of both calcium and fluoride in the nanoparticle is improved when both salts are used. Alternatively, the nanoparticle may be used without added calcium and/or fluoride. The nanoparticles may be useful for tooth remineralization, the treatment of dentinal hypersensitivity, to treat caries, or as a diagnostic agent to locate carious lesions.
Abstract: An aqueous oral care one-part composition (e.g., solution), a kit that includes such composition (e.g., solution), and methods (e.g., a method of providing fluoride to a patients tooth surface), wherein the oral care composition (e.g., solution) includes: silver cations; thiocyanate anions; fluoride anions; and water.
Type:
Grant
Filed:
July 25, 2019
Date of Patent:
June 6, 2023
Assignee:
3M INNOVATIVE PROPERTIES COMPANY
Inventors:
Yizhong Wang, Ta-Hua Yu, Joel D. Oxman, Richard P. Rusin
Abstract: The present invention is directed to a composition in solution (often, an aqueous solution) which comprises a combination of molecular iodine (I2) and an acceptable source of iodate (IO3), and an acid (inorganic or organic), wherein iodide and iodate are present in the composition at a molar ratio of about 0.1 to about 25, the concentration of uncomplexed molecular iodine is a disinfectant, biocidal and/or antimicrobial (depending upon the end use of the composition) effective amount the concentration of acid in the composition is effective to provide a buffering pH in the composition ranging from about 1.5 to about 6.5. Compositions according to the present invention are storage stable for unexpectedly long periods of time (up to about 5 years), and find use as disinfecting solutions, as germicides and/or biocides (e.g. antiviral, antibacterial, antifungal, antispore etc.
Type:
Grant
Filed:
November 30, 2021
Date of Patent:
May 23, 2023
Assignee:
IOTECH INTERNATIONAL, INC.
Inventors:
Rodger Elliot Kolsky, Herbert Moskowitz, Jack Kessler
Abstract: The present invention provides a patch for attaching to teeth or a surrounding part of teeth, and the patch can be easily removed by tooth brushing alone.