Abstract: An oral care composition, including a catalyzing enzyme and an anhydrous matrix configured to at least partially stabilize the catalyzing enzyme, wherein the anhydrous matrix includes a source of hydrogen peroxide, an acyl donor, a non-aqueous anhydrous liquid, and a surfactant mixture including sodium lauryl sulfate (SLS), Betaine, and a poloxamer.

Abstract: A chewable composition for teeth-whitening comprising a first region and a second region separated by a barrier layer; the first region comprising carbamide peroxide having water content of about 2% or less, a wetting agent (e.g., glycerin), an anhydrous chewing gum base having water content of about 1% or less, an anhydrous fruit acid, and one or more gum additives; and the second region comprising a chewable composition comprising a gum base, a source of bicarbonate ion, and one or more gum additives. A kit comprising separate chewable compositions corresponding to the first and second regions, and methods for whitening teeth using the chewable composition are also provided.

Abstract: The present invention provides calcium carbonate-based oral care compositions, in particular toothpastes comprising a thickening system comprising 0.2-0.5 wt. % xanthan gum and 0.2-0.5 wt. % synthetic polyacrylic acid polymer, as well as methods of using these compositions.

Abstract: The present disclosure relates to a pump-type toothpaste composition which can be provided by being comprised in a pump-type container, and particularly, relates to a pump-type toothpaste composition with improved feeling of use when brushing teeth. In addition, the present disclosure relates to a pump toothpaste composition having improved tailing and dry-hardening property. The pump-type toothpaste composition of the present disclosure may comprise a hydrocolloid.

Abstract: In various embodiments a dental varnish system having improved peptide release and fluoride release properties is provided. In various embodiments a dental varnish system that provides release of an antimicrobial peptide, or specifically targeted antimicrobial peptide (STAMP), e.g., the peptide C16G2, is provided, with or without a fluoride. In various embodiments, a dental varnish system that provides release of a fluoride, with or without an antimicrobial peptide or STAMP is provided. In certain embodiments the dental varnish system comprises a first component that is a dry powder, said first component comprising a an antimicrobial peptide, with or without a fluoride, and a bulking agent, and a second component that is a fluid, said second component comprising a varnish solution, where combination of said first component with said second component provides a varnish formulation for application to the surface of a tooth.

Abstract: The present invention relates to solid pharmaceutical compositions, in particular to oral contraceptives, comprising a progestogen, such as drospirenone; an estrogen, such as ethinylestradiol; a tetrahydrofolic acid or a pharmaceutically acceptable salt thereof, such as calcium 5-methyl-(6S)-tetrahydrofolate; and at least one pharmaceutical acceptable excipient or carrier. The compositions of the invention provide good stability of the tetrahydrofolic acid upon storage while still ensuring a fast and reliable release of the estrogen and the progestogen present in the composition.

Abstract: An oral care composition for alleviating dentin hyperesthesia is disclosed. The oral care composition includes a peptide consisting of an amino acid sequence of the following Formula 1: K—Y-R1-R2-R3-R4-R5-R6-R7-R8??(Formula 1) wherein R1 is arginine (R), lysine (K) or glutamine (Q); R2 is arginine (R) or glutamine (Q); R3, R4, and R5 are arginine (R) or lysine (K), respectively; R6 is asparagine (N) or serine(S); and R7 and R8 are lysine (K) or tyrosine (Y), respectively.

Abstract: An oral varnish comprising a combination of two different viscosity dimethicone components, wherein the difference between the two different viscosity dimethicone components is about 2.0 million cP or greater; and comprising at least one active ingredient, which is preferably a fluoride donor.

Abstract: The present invention relates to core shell silica particles, wherein each core shell silica particle comprises a silica core, and a surface of the silica core is etched with metal silicate, the core shell silica particles prepared by: i) admixing an amount of silica particles in water with an amount of a base, wherein the base comprises a monovalent metal ion, to produce core shell silica particles, each core shell silica particle comprising a silica core, and a surface of the silica core etched with a silicate of the monovalent metal ion; and ii) reacting the core shell silica particles formed in step i) with a metal salt comprising a second metal ion, to form core shell silica particles comprising silicate of the second metal ion on the surface of the silica core.

Abstract: Consumable abrasive-containing oral hygiene tablets are described. The tablets include glycine as an abrasive. The glycine average (Mv) particle size may be greater than 45 ?m. The tablets may be used with an oral irrigator and, when placed in the irrigator's fluid flow path, may disintegrate, release the abrasive, and improve the cleaning efficacy of the irrigator.

Abstract: Methods and kids for removing calculus from a tooth. The method can include applying a component A comprising a hydrogen peroxide or a precursor thereto and a component B the comprising a catalase to the tooth, thereby generating oxygen; and removing at least a part of the calculus from the tooth.

Abstract: A pharmaceutical paste formulation containing an active ingredient, an API solubilizer, a cross-linking agent, a consistency improver, a rheology modifier, a humectant, and a liquid base.

Abstract: Oral care compositions are disclosed. The compositions include hypochlorous acid in combination with one or more of a rheology agent, an abrasive, a surfactant, a buffer, or an inorganic compound. Methods of using and making the dentifrice compositions are also disclosed.

Abstract: An antimicrobial composition comprising: a) C2-C8 alkylated polyvinylpyrrolidone polymer; and b) biocidal agent selected from the group consisting of quaternary ammonium compounds, chlorohexidine salts, polymeric biguanides, organic acids, hydrogen peroxide, tertiary alkyl amines, iodophors and mixtures thereof.

Abstract: A toothpaste composition includes a structurant and a thickener, wherein the toothpaste composition has a predetermined viscosity and phase angle by using the structurant instead of reducing the content of a thickener, and thereby has an improved release property during use while maintaining a shape retention property of the toothpaste, and has an improved feeling of refreshment, flavor releasing power, cleaning power, and stain removal power. Further, provided is a toothpaste composition including a chelating agent containing phosphate and silica, wherein the chelating agent is supersaturated to precipitate phosphate to provide strong cleaning power, a whitening effect, a stain removal effect, and a crunchy sensation. Further, provided is a toothpaste composition including a peroxide, a thickener, and a spreading agent, wherein the peroxide and the thickener are separated from each other, providing excellent sense of use, stability, and a whitening effect in an anhydrous state.

Abstract: Provided are compositions and methods for treating or preventing nausea and vomiting in patients undergoing chemotherapy, radiotherapy, or surgery.

Abstract: A soluble fiber lozenge provided herein includes a body that is partially or wholly receivable in an oral cavity. The body includes a soluble-fiber matrix and one or more additives dispersed in the soluble-fiber matrix. In some cases, a soluble fiber lozenge provided herein includes at least 40 weight percent of soluble fiber. In some cases, soluble fiber in soluble fiber lozenge provided herein can include maltodextrin. The soluble fiber lozenge is adapted to release one or more additives from the body when the body is received within the oral cavity of a consumer and exposed to saliva. A method of making soluble fiber lozenges provided herein includes forming a molten mixture of at least 40 weight percent soluble fiber, one or more additives, and less than 15 weight percent water while maintaining a mixture temperature of less than 200° C. and portioning the molten mixture into a plurality of soluble fiber lozenges. In some cases, the ingredients can be mixed to form the molten mixture in an extruder.

Abstract: The present disclosure provides a patch which is attached to a tooth or oral mucous membrane and releases an active ingredient to a portion attached, in which the patch comprises a drug layer having an adhesive surface attached to the tooth or oral mucous membrane and a backing layer laminated on the drug layer, and comprises at least one reticular structure inside the drug layer, and is divided into at least 2 drug layers at the boundary of or by the reticular structure.

Abstract: The present disclosure provides an oral care composition including a water-miscible base component, an amorphous calcium phosphate remineralizing component including a water-soluble or partially water-soluble calcium component and a water-soluble inorganic phosphate component, and a tartar control component, wherein the oral care composition provides enamel fluoride uptake activity and tartar control activity.

Abstract: Provided is a liquid collecting device, which comprises a collecting container, wherein the collecting container is provided with a diversion cavity for diverting a body fluid collected; on a wall of the collecting container, at least one jacket cavity configured to store a storage liquid is provided, the jacket cavity is provided around the diversion cavity, and the jacket cavity extends along an axial direction of the diversion cavity, and a cross section of the jacket cavity is annular; and the diversion cavity has an inflow port and an outflow port, and an aperture of the inflow port is larger than that of the outflow port.