Abstract: A method for preventing oral diseases caused by dental biofilm and plaque accumulation, such as gingivitis and periodontitis by application of a single-phase stabilized chlorine dioxide composition at a concentration range of about 0.005% to about 0.800% (w/v) at a pH in the range of 6.0 to 7.4. The bactericidal properties of stabilized chlorine dioxide include reduction (kill) of anaerobic/aerobic/facultative gram-negative and gram-positive oral bacteria occurring in plaque or polymicrobial biofilms. The composition may be in the form of wash, rinse, soak, paste, gel, aerosol spray, or other suitable delivery system.

Abstract: Described herein are oral compositions comprising an extract obtained from Arialaceae, Zingiberaceae, Lamiaceae, Fabaceae, Solanaceae, Punicaceae. Asteraceae or mixtures thereof; Their uses for alleviating dry mouth is also described.

Abstract: The present invention relates to compositions and methods for mineralizing a dental surface or subsurface including providing a composition including stabilized ACP and a source of fluoride ions.

Abstract: A composition having a short disinfecting contact time is disclosed. The composition contains a biguanide or guanide, a quaternary ammonium compound and a basic compound in a specific weight ratio to one another. Compositions having less than a two minute disinfection time are disclosed.

Abstract: A multi-film delivery system for a multi-component tooth whitening, desensitization and remineralization composition is disclosed which comprises a first orally dissolvable film made of a liquid-soluble or liquid dispersible polymer system containing a peroxide activation compound or complex and desensitizing agents and/or remineralizing agents and/or anti-inflammatory agents, and a separate second undissolvable film containing a tooth whitening peroxide compound, such as hydrogen peroxide or carbamide peroxide, stabilizers and thickeners, and/or desensitizing agents and/or remineralizing agents and/or anti-inflammatory agents, which, when applied together on teeth surfaces, the peroxide activation compound/complex on the first film activates the peroxide compound on the second film, and accelerates the release of active bleaching radicals for accelerated whitening action. The first and second films are maintained separate from one another until application.

Abstract: Disclosed herein are teeth whitening compositions generally including an oxidizing agent, and an activating agent that has an emission wavelength between about 400 nm and about 570 nm. Methods of employing these compositions to whiten teeth, methods of making these compositions and kits that include some or part of the composition ingredients, are also described.

Abstract: The present invention relates material that is useful in drug delivery compositions. The material comprises cellulose nanofibers and/or derivatives thereof, wherein the cellulose nanofibers are in a form of a hydrogel or membrane. The invention also provides methods for producing these materials and compositions and uses thereof.

Abstract: An anti-microbial preservative for use in ophthalmic and dermatologic products. The preservative includes from about 0.005 wt. % to about 0.20 wt. % chlorite compound and from about 0.005 wt. % to about 0.05 wt. % peroxy compound. Additionally, the preservative does not generate chlorine dioxide within the pH range of 5.0-8.8. Also included are an antimicrobial ophthalmic and dermatologic compositions for direct application onto an eye or skin of a living being including from about 0.005 wt. % to about 0.20 wt. % chlorite compound and from about 0.005 wt. % to about 0.05 wt. % peroxy compound. Also included are methods for treating dryness of the eyes and skin disorders (e.g., wounds, burns, infections, ulcerations, psoriasis, etc.) and for disinfecting and cleansing contact lenses while in place upon an eye by applying the composition to the eye or to the contact lens.

Abstract: Provided are compositions and methods for preventing dental caries, as well as aqueous compositions and methods for improving the mechanical strength of teeth.

Abstract: The present invention discloses a method of treating a disease condition susceptible to baclofen therapy, said method comprising orally administering once-a-day in the evening a controlled release drug delivery system comprising baclofen or its pharmaceutically acceptable salt or its derivatives and pharmaceutically acceptable excipients.

Abstract: The present disclosure relates to anhydrous hydrogels useful as mucoadhesive (oral compositions) or as topical agents and may be used to deliver an active agent such as active pharmaceutical agents (API's), coagulants, fragrances, flavors, and other actives and excipients.

Abstract: A probiotic formulation includes the following: lactobacillus acidophilus comprising 15.0% to 40.0% per mass of the probiotic formulation; lactobacillus reuteri comprising 5.0% to 20.0% per mass of the probiotic formulation; lactobacillus salivarius comprising 5.0% to 20.0% per mass of the probiotic formulation; lactobacillus paracasei comprising 5.0% to 20.0% per mass of the probiotic formulation; streptococcus thermophiles comprising 5.0% to 20.0% per mass of the probiotic formulation; streptococcus salivarius BLIS K-12 comprising 5.0% to 30.0% per mass of the probiotic formulation; streptococcus salivarius BLIS M-18 comprising 5.0% to 30.0% per mass of the probiotic formulation; zinc oxide comprising 0.2% to 5.0% per mass of the probiotic formulation; hydroxyapatite comprising 0.1% to 25.0% per mass of the probiotic formulation; and dicalcium phosphate comprising 0.1% to 5.0% per mass of the probiotic formulation. The probiotic formulation may be formed into a lozenge or a gum.

Abstract: The present invention relates to ophthalmic solutions and devices comprising at least one water soluble polymer having a molecular weight of at least about 500,000 Daltons and comprising linear or branched polyether pendant groups having a molecular weight of at least about 300.

Abstract: Disclosed are therapeutic oral compositions useful in the treatment of a variety of oral disorders, in which the composition can provide blockage of dentinal tubes, while at the same time provide antibacterial and anti-caries efficacy. The compositions include arginine in free or salt form, a mucoadhesive polymer, and at least one component selected from pyrophosphates, zinc salts, potassium salts, strontium salts, and mixtures thereof.

Abstract: Methods, compositions, and products maintain white teeth or prolong the effects of teeth whitening by preventing staining of teeth via a temporary stain repellent. The temporary stain repellent can include a food-grade silicone compound configured to temporarily form a protective layer over teeth or fill the pores of the teeth before and during the consumption of pigmented foods and/or drinks post-teeth whitening.

Abstract: Described herein are compositions comprising antibacterially effective amounts of a compound of Formula (I): or a salt thereof in which R1 and R2 are each independently (C1-C6) alkyl or (C2 C6) alkenyl, and a carrier. Suitable carriers include orally acceptable carriers and dermatologically acceptable carriers. The disclosed compositions include oral care and personal care compositions useful for treating or preventing oral and skin conditions, respectively.

Abstract: Described herein are oral care compositions comprising (i) an orally acceptable gallium salt and (ii) a basic amino acid polymer, in amounts effective to disrupt biofilm; and methods of making and using the same.

Abstract: A method of cleaning an oral appliance allows a dental patient or other oral appliance wearer to clean the appliance while the appliance is in place in the wearer's mouth. The appliance wearer dispenses a quantity of foamed, cleanser formulation into to his or her mouth, swishes the cleanser around in the mouth for a desired amount of time, and then expectorates any remaining cleanser. A cleaning kit for an oral appliance is also provided and includes a mixture of water, hydrogen peroxide, and at least one surfactant in a foam-dispensing bottle.

Abstract: A combined dental whitening, polishing, and re-mineralizing liquid formula includes an oxidizer; an abrasive; mineral salt; and a catalyst.

Abstract: The present invention relates an oral care composition, comprising one or more functional agents selected from a group consisting of a whitening agent, a re-mineralizing agent, an anti-plaque agent, an anti-gingivitis agent, a detoxifying agent and its combinations. The composition further comprises a probiotic blend consisting of beneficial oral bacterial population and at least one essential oil comprising antimicrobial activity.