Patents Examined by William Frehe
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Patent number: 10010447Abstract: A retinal treatment system for delivering therapeutic agents to a target location with a retina is disclosed herein. The retinal treatment system includes a console having a control system and a handheld device coupled to the control system. The handheld device includes an inner tube disposed within an outer tube and being axially moveable within the outer tube. The inner tube has a perforating tip that is configured to perforate an inner limiting membrane of the retina. The handheld device further includes a chamber coupled to a proximal end of the inner tube that is configured to receive a fluid containing therapeutic agents injectable from the perforating tip. The control system of the retinal treatment system permits a user to maintain a position of the handheld device relative to the retina and activate an injection of a portion of the fluid through the inner tube into the retina.Type: GrantFiled: December 18, 2013Date of Patent: July 3, 2018Assignee: Novartis AGInventors: Pooria S. Kashani, Michael Papac
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Patent number: 9974931Abstract: This present invention concerns a new combination of balloon catheters and formulations containing active substances that adhere to the surface of the balloon membrane. Furthermore the present invention concerns coating processes for the manufacture of these balloon catheters as well as their use in the treatment and prophylaxis of vascular diseases.Type: GrantFiled: December 14, 2015Date of Patent: May 22, 2018Assignee: Invatec Technology Center GMBHInventors: Bruno Scheller, Ulrich Speck
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Patent number: 9974673Abstract: A system for deploying a shape memory catheterization device within a patient, includes a catheter for endovascular insertion of the shape memory catheterization device. A heat source heats the shape memory catheterization device above the transition temperature. A transformation data generator includes a circuit driver for driving a circuit that includes at least one inductive element of the shape memory catheterization device and a detection circuit for generating transformation data based on an inductance of the at least one inductive element, wherein the transformation data indicates a shape transformation of the shape memory catheterization device from a catheterization shape to a transformed shape.Type: GrantFiled: August 1, 2013Date of Patent: May 22, 2018Assignee: Memory Effect Medical, LLCInventors: Christine Laramy, Bruce Stuckman
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Patent number: 9956351Abstract: A dose delivery device is disclosed wherein a dose can be set by rotating a dose setting member, whereby a push button (4) is elevated from one end of the device a distance proportional to the set dose from a position fixed relative to the housing, and wherein the set dose can then be injected by pressing the push button back to its non-elevated position, through which motion a piston rod will move approximately the same distance. The invention provides a method of forcing a numbered scale drum to rotate both during dose setting and injection to allow the user to read the remaining dose at any time during setting and injecting a dose.Type: GrantFiled: November 19, 2010Date of Patent: May 1, 2018Assignee: Becton, Dickinson and CompanyInventor: Claus Schmidt Møller
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Patent number: 9950116Abstract: A method and system for providing a drug delivery device. The drug delivery device comprises a dose setting mechanism comprising a spindle and a cartridge holder coupled to the dose setting mechanism. The cartridge holder comprising a cartridge having a movable bung at one end of the cartridge. The cartridge holder must be rotated before a dose may set with the dose setting mechanism.Type: GrantFiled: May 27, 2010Date of Patent: April 24, 2018Assignee: Sanofi-Aventis Deutschland GmbHInventors: David Aubrey Plumptre, James Alexander Davies, Christopher John Jones, Robert Frederick Veasy
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Patent number: 9943647Abstract: A pharmaceutical injection device comprises a main body case (2); a pharmaceutical syringe mounting component (3) that is provided inside the main body case (2) and onto which a pharmaceutical syringe (4) is mounted; a piston (5) provided movably with respect to the pharmaceutical syringe (4) mounted onto the pharmaceutical syringe mounting component (3); a drive mechanism (6) for driving the piston (5); a memory (46) that stores a preset pharmaceutical injection schedule; and a controller (7) that resets a current pharmaceutical dose by comparing a planned cumulative pharmaceutical dose, which is a planned cumulative amount of pharmaceutical injected up to the last time on the basis of the pharmaceutical injection schedule stored in the memory, and an actual cumulative pharmaceutical dose, which is a cumulative amount of pharmaceutical actually injected up to the last time.Type: GrantFiled: October 5, 2012Date of Patent: April 17, 2018Assignee: PANASONIC HEALTHCARE HOLDINGS CO., LTD.Inventors: Yasutaka Mukai, Seiji Kikuchi, Tsuguhiro Kondoh
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Patent number: 9940441Abstract: An ambulatory infusion pump can include a maximum bolus override procedure. When a bolus amount greater than a maximum bolus amount is requested, the pump can provide an alert indicating that the amount requested exceeds the maximum bolus amount. If the user confirms the request in response to the alert, the bolus amount can be delivered to the user. The amount delivered in response to the confirmation can be a first portion of the bolus amount. A reminder can then be provided that a second portion of the bolus amount that is a remaining portion of the requested bolus amount was also requested. If a second confirmation is received in response to the alert, the second portion of the bolus amount can also delivered to the user.Type: GrantFiled: March 13, 2013Date of Patent: April 10, 2018Assignee: Tandem Diabetes Care, Inc.Inventor: John Walsh
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Patent number: 9937124Abstract: Electromechanical substance delivery devices are provided which implement low-power electromechanical release mechanisms for controlled delivery of substances such as drugs and medication. For example, an electromechanical device includes a substrate having a cavity formed in a surface of the substrate, a membrane disposed on the surface of the substrate covering an opening of the cavity, and a seal disposed between the membrane and the surface of the substrate. The seal surrounds the opening of the cavity, and the seal and membrane are configured to enclose the cavity and retain a substance within the cavity. An electrode structure is configured to locally heat a portion of the membrane in response to a control voltage applied to the electrode structure, and create a stress that causes a rupture in the locally heated portion of the membrane to release the substance from within the cavity.Type: GrantFiled: September 11, 2014Date of Patent: April 10, 2018Assignee: International Business Machines CorporationInventors: S. Jay Chey, Bing Dang, John U. Knickerbocker, Kenneth F. Latzko, Joana Sofia Branquinho Teresa Maria, Lavanya Turlapati, Bucknell C. Webb, Steven L. Wright
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Patent number: 9884156Abstract: The invention is related to an apparatus comprising a dispense interface for use with a drug delivery device, the dispense interface comprising a lockout element being arranged at least partially between an outer body of the dispense interface and an inner body of the dispense interface and wherein the lockout element is configured to be removeably maintained in a first position, such that when the dispense interface is first attached and then removed from said drug delivery device, the lockout element moves into a second position, wherein the lockout element in the second position is configured to prevent said dispense interface from being reattached to a drug delivery device.Type: GrantFiled: April 26, 2012Date of Patent: February 6, 2018Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Marc Holtwick, Ilona Eggert, James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
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Patent number: 9878089Abstract: An apparatus and method are disclosed for controlling infusion of liquid into a patient using a peristaltic pump. The liquid infusion apparatus includes a liquid conduit having a proximal segment, a distal segment and an intermediate segment. The liquid infusion apparatus also includes a flow valve in fluid communication with the intermediate and distal segments. The flow valve includes a shuttle member slidably disposed within a housing about the distal segment, the shuttle member being configured for lateral movement relative to an elongated axis of the distal segment. The shuttle member is configured to operate in a first configuration to impede fluid flow through the liquid conduit and in a second configuration for which fluid flow through the liquid conduit is unimpeded. The shuttle member includes a resilient grasper for selectively engaging and disengaging a mating actuator resiliently received by the grasper.Type: GrantFiled: June 20, 2013Date of Patent: January 30, 2018Assignee: IRADIMED CORPORATIONInventor: Roger E. Susi
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Patent number: 9849244Abstract: A drug delivery device is provided comprising a dose setting mechanism having a spindle and a cartridge holder coupled to the dose setting mechanism. The cartridge holder comprising a cartridge having a movable bung at one end of the cartridge. The cartridge holder must be rotated before a dose may set with the dose setting mechanism.Type: GrantFiled: May 28, 2010Date of Patent: December 26, 2017Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: David Plumptre, James Davies, Christopher Jones, Robert Veasey
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Patent number: 9839584Abstract: A nasogastric tube (10) including a main lumen (12) having one or more proximal connectors (14) for connecting to a source of substances or pressure, and one or more vacuum lumens (16) peripherally surrounding the main lumen (12), each vacuum lumen (16) including a vacuum sealing portion (24), which includes one or more suction ports (26) for sealingly drawing an inner wall of an esophagus thereagainst.Type: GrantFiled: July 16, 2012Date of Patent: December 12, 2017Assignee: NUTRISEAL LIMITED PARTNERSHIPInventors: Avinoam Nevler, Orit Shaked, Eyal Haytman
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Patent number: 9827169Abstract: A system comprising: a nasogastric tube comprising: (a) a main lumen having one or more proximal connectors for connecting to a source of substances or pressure, (b) at least four vacuum lumens peripherally surrounding said main lumen, (c) at least four suction ports for sealingly drawing an inner wall of an esophagus thereagainst, each of said at least four suction ports associated with a different one of said four vacuum lumens, wherein said at least four suction ports are distributed between at least two different locations along a longitudinal axis of said nasogastric tube; and an imaging system for capturing and rendering one or more images of an area accessible by said tube, said imaging system comprising: (d) a camera disposed at a distal end of said nasogastric tube, for capturing said images; (e) an illuminator disposed at said distal end of said nasogastric tube, and (f) a processing unit provided at a proximal end of said nasogastric tube, that is configured to receive and process said captured imaType: GrantFiled: December 1, 2014Date of Patent: November 28, 2017Assignee: NUTRISEAL L.P.Inventors: Doron Besser, Guy Ben Ezra
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Patent number: 9795732Abstract: Apparatus are provided for infusion devices and related systems and operating methods. An exemplary system includes a motor, a sensing arrangement coupled to the motor to provide output indicative of a detected characteristic of the motor when the sensing arrangement is enabled, and a module coupled to the sensing arrangement to periodically enable the sensing arrangement while the motor is idle and detect potential unintended motion of the motor based on the output from the sensing arrangement while periodically enabling the sensing arrangement. In some embodiments, the motor includes a rotor configured such that its rotation provides translational displacement of a plunger in a fluid reservoir, and the sensing arrangement includes one or more sensors configured to provide output indicative of a detected magnetic field of the rotor magnet.Type: GrantFiled: August 4, 2016Date of Patent: October 24, 2017Assignee: Medtronic MiniMed, Inc.Inventors: Adam S. Trock, Hsiao-Yu S. Kow, Nichole R. Mattson, Steve Chow, Alexander S. Campbell
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Patent number: 9795737Abstract: Methods and systems for controlling an insulin pump in response to glucose measurements are responsive to a base insulin delivery profile and a temporary insulin delivery profile. These can be used, e.g., to control blood glucose level of a subject using a continuous glucose monitor and an insulin infusion pump. During a selected time range, an insulin amount for the pump to supply is determined using the temporary insulin delivery profile. Outside that time range, the insulin amount is determined using the base insulin delivery profile. The temporary insulin delivery profile can specify an exact amount to be supplied (a “hard” profile), a nominal amount to be supplied if doing so does not drive glucose out of a desired zone (“soft”), or a soft profile with a minimum amount of insulin to be delivered (“semi-soft”).Type: GrantFiled: March 15, 2013Date of Patent: October 24, 2017Assignee: ANIMAS CORPORATIONInventors: Daniel Finan, Thomas McCann
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Patent number: 9789029Abstract: A system comprising: a nasogastric tube comprising: (a) a main lumen having one or more proximal connectors for connecting to a source of substances or pressure; (b) at least four vacuum lumens peripherally surrounding said main lumen; and (c) at least four suction ports for sealingly drawing an inner wall of an esophagus thereagainst, each of said at least four suction ports associated with a different one of said at least four vacuum lumens, wherein said at least four suction ports are distributed between at least two different locations along a longitudinal axis of said nasogastric tube.Type: GrantFiled: December 5, 2013Date of Patent: October 17, 2017Assignee: NUTRISEAL LIMITED PARTNERSHIPInventors: Doron Besser, Guy Ben Ezra, Avinoam Nevler, Orit Shaked, Eyal Haytman
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Patent number: 9789261Abstract: An auto-injector comprising an elongate housing containing a syringe. The housing having a an orifice intended to be applied against an injection site. The syringe is slidably arranged with respect to the housing. A spring pushing the needle from a covered position into an advanced position, operating the syringe and covering the needle. An activator arranged to lock the spring prior to manual operation and capable of, upon manual operation, releasing the spring means for injection. A first gear arrangement and a second gear arrangement arranged for converting torque from a first end and a second end of the torsion spring into a translative force. The first end groundable in the housing while the second end acts on a plunger through the second gear arrangement for advancing the needle and supplying the dose.Type: GrantFiled: December 21, 2011Date of Patent: October 17, 2017Assignee: Sanofi-Aventis Deutschland GMBHInventors: Thomas Mark Kemp, Timothy Donald Barrow-Williams, Matthew Ekman
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Patent number: 9770562Abstract: An apparatus is presented comprising a lock out member configured to be implemented into a medical device, in particular a dispense interface, attachable to a second medical device, in particular a main body, wherein said lock out member is configured to prevent a second attachment of said medical device to said second medical device, wherein said lock out member has at least a first area with a first cross-sectional area, wherein said lock out member has at least a second area having a second cross-sectional area smaller than the first cross-sectional area, such that an electric resistance is defined between opposite ends of the lockout member and wherein said lock out member, at least in the second area, is made of a conductive material.Type: GrantFiled: May 4, 2012Date of Patent: September 26, 2017Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBHInventor: Christiane Nessel
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Patent number: 9731063Abstract: A portable functional vaginal cleansing apparatus is provided to prevent inflammation in vagina, to maintain cleanness, and to enhance massage effect. A portable functional vaginal cleansing apparatus comprises: a doughnut-shaped main body; a semicylinder water tank with a water level indicator (100) on the outside and a coupling protrusion inside; a handle part (380) with a coupling groove mounted at the coupling protrusion; a pumping unit (210) with a motor and a pump; and a control unit (290) with a rotator which is formed to rotate within a predetermined range, a insertion protrusion connected to a hose, an insertion unit with a nozzle part, an on and off switch, a water level controller, and an operation lamp.Type: GrantFiled: December 12, 2011Date of Patent: August 15, 2017Inventors: Mi Chong Shin, In Sung Shin
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Patent number: 9731104Abstract: A dual reservoir access port includes a base having proximal and distal fluid reservoirs. The fluid reservoirs each comprise a bottom and a side wall. A dual prong outlet stem projects from a distal end of the base and comprises a first prong and a second prong. A first fluid channel extends through the first prong to the distal reservoir, and a second fluid channel extends through the second prong to the proximal fluid reservoir. A puncture shield is disposed between at least a portion of the second fluid channel and the bottom of the distal fluid reservoir. A needle-penetrable septum is disposed atop of each of the fluid reservoirs. A cap is placed over and around the port base compressing and sealing the septa against the base. A locking collar may be placed over a dual lumen catheter to lock the catheter to the dual prong outlet stem.Type: GrantFiled: April 22, 2011Date of Patent: August 15, 2017Assignee: Medical Components, Inc.Inventors: Christopher Linden, Raymond Bizup, Cristian M. Ciuciu