Abstract: An insertion device, generally used with an infusion set, including a needle being adapted for puncturing at one end and including at the opposite end a hub. The hub includes a handle part and a guard part that are capable of securing the needle through the use of locks. Locking structures are used to secure the insertion device in a position where the needle is covered in a locked position, avoiding unintended contact with the needle.

Abstract: The present invention relates to apparatus for retroperfusion of tissues and organs. The apparatus comprises a catheter with a proximal end for engaging a supply of the fluid medium, and a distal end having an expandable-contractible chamber for installation into suitable vessels or organs. The expandable-contractible chamber comprises a conduit element having a fluid-filled hollow wall defining a lumen. The conduit element has a first deformable inner-facing section approximate a proximal end of the conduit and a second deformable inner-facing section approximate a distal end of the conduit element. Controlled application of a pressure at a proximal end of the conduit element causes deformation of the conduit into the lumen at its distal end thereby occluding the flow of fluid medium through the catheter. Controlled release of the pressure releases deformation of the fluid-filled conduit at its distal end thereby unblocking the flow of the fluid medium through the catheter.

Abstract: An injection device includes a multi-use drive assembly 10 and a single use disposable syringe assembly 12 releasably connected thereto. The syringe assembly includes a syringe 18 and a shield 26 mounted for telescopic movement. The drive assembly 10 is operable to extend the syringe 18 relative to the shield 26 and then to express a dose. Continued forward drive movement extends the shield 26 to re-cover the syringe needle 22 and then ejects the spent syringe assembly 12 in a safe (shrouded) condition.

Abstract: A system for tracing tubing which forms a conduit from a source of infusion liquid to a patient by way of an infusion pump has a vibration generator manually operable by a user to generate vibrations at an origin location along the tubing, wherein the vibrations are propagated by the tubing and have a vibration signature. A vibration sensor arranged at a destination location along the tubing receives the vibrations and generates a digital vibration signal. Signal processing circuitry connected to the vibration sensor processes and evaluates the digital vibration signal to determine a trace status of the tubing between the vibration generator and the vibration sensor. An indicator connected to the signal processing circuitry provides an indication of the determined trace status. Trace status possibilities include clear, cross-over, and null. A likely number of cross-overs may also be indicated.

Abstract: The invention relates to a front end for an auto-injector, the front end comprising a syringe with an injection needle and a stopper, wherein the syringe is slidably arranged within a syringe retainer, wherein an outer sleeve for preventing access to the needle is removably arrangeable over the syringe retainer, wherein the syringe retainer comprises a screw thread for connecting it to a correspondent screw thread of a mounting of a re-usable auto-injector back end comprising a drive means for advancing the syringe and needle in a proximal direction for needle insertion and for advancing the stopper within the syringe for injection, wherein a resilient locking barb is arranged to rotationally lock the syringe retainer to the mounting in an unscrewing direction when the front end is screwed to the re-usable back end and when the outer sleeve is removed, wherein the outer sleeve is arranged to unlock the resilient locking barb when arranged over the syringe retainer.

Abstract: The present invention relates to a breast pump operable to generate a negative pressure comprising a funnel (24) for receiving a breast of a user. The breast pump (24) has an insert (50,70) receivable in the funnel (24) having a deformable region (59a-59e) which forms a chamber between the insert (50,70) and the funnel (24) when the insert (50,70) is received in the funnel (24). A passageway (37) connecting the chamber to the source of negative pressure is formed in the funnel (24) so that, during use, the deformable region (59a-59e) is deformed and/or deflected relative to the breast of a user in response to a negative pressure in the chamber.

Abstract: This present invention concerns a new combination of balloon catheters and formulations containing active substances that adhere to the surface of the balloon membrane. Furthermore the present invention concerns coating processes for the manufacture of these balloon catheters as well as their use in the treatment and prophylaxis of vascular diseases.

Abstract: The invention relates to a Luer lock connection comprising a Luer cone and a threaded sleeve surrounding said cone, the threaded sleeve being fitted on the base of the Luer cone so that it is rotatable along the longitudinal axis of said cone, wherein clamping means are provided between the threaded sleeve and the base of the Luer cone, said means being designed in such a way that when a female part is fitted onto the Luer cone, clamping between the threaded sleeve and the base of the Luer cone is achieved by rotating the threaded sleeve or the female part in the threaded sleeve (4).

Abstract: A fluid injecting apparatus includes: a cartridge portion which has a tube that transports a fluid, a plurality of fingers that press the tube, and a blocking member that blocks the tube; and a main body portion which has a cam that presses the plurality of fingers. When the cartridge portion is detached from the main body portion, the blocking member blocks the tube. When the cartridge portion is mounted to the main body portion, the cam presses at least one of the fingers such that the tube is blocked at the position of the pressed finger and the blocking of the tube by the blocking member is released.

Abstract: A medical needle, kit, and pharmacological composition of matter comprising a local anesthetic pertaining to inserting a needle percutaneously in a patient is disclosed. A method is disclosed with the needle having a leading apex that is dulled to restrict penetration through articular cartilage, advancing the needle leading apex into a bone joint and stopping said needle leading apex short of substantially penetrating bone joint articular cartilage, and injecting through the needle lumen a pharmacological composition of matter comprising a local anesthetic and out of said opening and into the bone joint to contribute to the anesthetizing of nerves near said bone joint.

Abstract: A fluid delivery catheter that uses micro-needles for fluid delivery though a vessel wall. The catheter may provide fluid delivery therapy for various procedures, such as, for example, delivery of tumescent fluid or renal denervation. The catheter includes an elongate member with deployable and retractable needles disposed about a distal end of the elongate member. The needles may be disposed radially about the distal end and/or along a length of the distal end.

Abstract: An improved spindle and bearing combination for a drug delivery device is provided that has a first connection between the spindle (1) and bearing (4) comprising a web (5) and a second connection that replaces the first connection when the web (5) is severed that allows the spindle (1) to rotate relative to the bearing (4).

Abstract: A drug delivery device comprises an outer housing rollable around a rotation axis and at least one stop member. The stop member protrudes radially from the outer housing of the drug delivery device and is configured to prevent rolling movement of the drug delivery device along a predetermined surface. The outer housing comprises a main housing and a dose member. The dose member is movable with respect to the main housing when setting and/or delivering a dose of a drug. The stop member comprises a first part and a second part, wherein the first part is arranged on the main housing and the second part is arranged on the dose member.

Abstract: A needleless injector syringe includes a tubular barrel containing a first chamber for receiving a liquid, a nozzle on a front end of the barrel, a piston which drives a plunger for discharging the liquid through the nozzle, a second chamber in which the piston slides, a third chamber in fluid communication with the second chamber for receiving gas from said second chamber during forward movement of the piston, and for carrying gas to the second chamber to cause the piston to retract, and a breach plug closing a rear end of the barrel for directing gas under pressure alternately against the rear end of the piston and to the third chamber for driving the piston between the discharge position and a retracted position.

Abstract: A catheter including one or more bidirectional valves is provided. The catheter includes a tubular body having proximal and distal ends, and inner and outer surfaces, and at least one valve formed near the distal end of the tubular body. The valve includes a deformation portion that defines a slit that is openable and closable. The openable/closable slit communicates from the inner surface to the outer surface of the tubular body, wherein the distance between the inner surface and the outer surface of the tubular body progressively becomes thinner approaching the openable/closable slit within the deformation portion.

Abstract: Disclosed are a syringe capable of measuring an inner temperature of a patient body and a method of manufacturing the same. In the syringe, a different metal from that of a syringe needle is deposited on an inclined surface of a tip portion of the syringe needle to form a thermocouple junction with the metal of the syringe needle, whereby the region causing pain in a patient body can be diagnosed while allowing administration of medicine thereto, thereby enabling efficient treatment and significantly reducing potential harm due to drug abuse.

Abstract: An improved drug delivery device is provided having a piston rod that incorporates on its proximal end at least one guidepost that is configured for transmitting axial and rotational forces from a drive mechanism. The device comprises a drug delivery device housing and a medicament contained in the drug delivery device housing.

Abstract: A peritoneal-based artificial kidney processes peritoneal fluid without need for additional fluids. Spent dialysate is separated into a protein-rich stream and a protein-free stream. The protein-rich stream is regenerated using a sorbent assembly, and its protein composition can be modified by removal of selected protein(s). Alternatively, the spent dialysate is first processed in a sorbent assembly and then separated into the protein-rich and protein-free streams. Immobilization of urease allows more protein rich fluid to be regenerated and re-circulated into the peritoneal cavity for toxin removal and allows practicable development of portable and wearable artificial kidneys.

Abstract: A catheter includes an inner layer, a braid, an outer layer, and a distal tip. A recessed region having a first side and a second side is formed in a distal end portion of the braid, a length of the first side being longer than the sum of a wire width of a first wire and a distance between two adjacent first wires, a length of the second side being longer than the sum of a wire width of a second wire and a distance between two adjacent second wires. The distal tip is bonded to the inner layer in the recessed region. By providing the recessed region, the number of peaks formed in the distal end portion of the braid is made smaller than that in the existing case.