Abstract: A method and system for managing delivery of a respiration gated defibrillation shock from a subcutaneous implantable medical device (S-IMD) having one or more extra vascular electrodes. The method and system sense cardiac events of a heart. Additionally, the method and system utilize one or more processors to declare a shockable arrhythmia based on the cardiac events, obtain a respiration proxy signal indicative of respiration, track a respiration state related (RSR) characteristic from the respiration proxy signal, gate delivery of a high voltage (HV) shock based on occurrence of a respiration-gated (RG) trigger in connection with the RSR characteristic, and deliver the HV shock along a shocking vector between extra vascular electrodes based on the RG trigger to time delivering of the HV shock to occur during the select state within the respiration cycle.

Abstract: The present invention relates to a stimulation generator suitable for use in an implantable neurostimulator, including an injectable neurostimulator. The stimulation generator is adapted to provide a configurable stimulation signal comprising a component, such as a pulse. The stimulation generator comprises circuitry to receive and combine an amplitude control signal and a duty cycle signal to produce a preliminary output voltage signal which includes the component of the stimulation signal. It further comprises a voltage-controlled current source adapted to be driven by the preliminary output voltage signal; and a mode selector controlled by a stimulation mode signal to output the component from the preliminary output voltage signal as a current-controlled component of the stimulation signal via the voltage-controlled current source or as a voltage-controlled component of the stimulation signal.

Abstract: A disposable, self-contained electro-stimulation device configured with paired cutaneous electrodes for placement over specific acupuncture and neurostimulation points (such P6) on a patient's wrist, delivering controlled electrical pulses to reduce or prevent nausea and vomiting following surgery or anesthesia. Its advanced circuitry trades boost-converter efficiency for total system energy conservation, optimized for the low-duty-cycle pulse output used in neuromodulation rather than continuous high-power operation. Its single-IC, digitally controlled pulse engine performs both biphasic stimulation and contact verification, optimizing it for compact, battery-powered wearable medical devices. It also uses a miniature Hall-effect magnetic-field sensor positioned over a planar helical trace that carries the stimulation current, producing a proportional magnetic field detectable by the Hall sensor for the non-invasive current detection and skin-contact verification.

Abstract: An active medical device has a feedthrough with at least two terminal pins that are connected to electronic components in the device housing. A lead connector is connected to a strain-relief device for a lead. The lead connector supports at least two proximally-facing C-shaped inserts with an annular spring nested therein that are detachably connected to the device terminal pins to thereby connect the device electronic components to the lead electrodes. The device housing has a length extending along a longitudinal axis, and secondary axes of the terminal pins connected to the C-shaped inserts/annular springs are aligned parallel to the axis with imaginary extensions of the connector axes extending into the device housing.

Abstract: The present invention relates to a flexible skin patch equipped with an ultra-thin LED assembly that emits light in a specific wavelength range and an invention for manufacturing the same, and is related to an invention capable of providing a flexible skin patch that has the excellent effect of promoting vitamin D production in a localized area of the skin, and has the effect of alleviating or treating local skin psoriasis, fungi, fungal tumors and eczema, and has excellent antiviral effect, and is easy to attach and detach.

Abstract: Systems and methods for detecting cardiac arrhythmia are discussed. A medical-device system includes an arrhythmia detector circuit and an event prioritizer circuit. The arrhythmia detector circuit can detect an atrial activation event from a cardiac electrical signal sensed from the patient, and determine an atrial fibrillation (AF) confidence indicator based on a signal characteristic of the atrial activation event. The event prioritizer circuit can generate an event priority for the AF event based on the AF confidence indicator. Multiple AF events may be prioritized in a specific order and presented to a user or a process.

Abstract: The present disclosure relates to systems and methods for activating a circuit of an implant device. Consistent with one implementation, an implant device is provided with a sensor including a working electrode (WE) and a counter electrode (CE). The sensor may be configured to generate a first current at the CE when the implant device is implanted in a body of a subject. A sensing circuit may also be provided that is electrically coupled to the WE of the sensor. The sensing circuit may be activated based on the first current and utilize the sensor to measure one or more parameters of an individual or other subject.

Abstract: A system may include a neuromodulator and a processing system. The neuromodulator may be configured to be programmed with a set of more than one program to deliver neuromodulation. The processing system may be configured to: receive sensed data indicative of activity, motion and/or posture of a patient; analyze the activity, motion and/or posture of the patient; and perform a process, based on the analyzed activity, motion and/or posture, for switching from one program in the set of more than one program to another program from the set of more than one program. The process may include automatically implementing the other program from the set of more than one program or suggesting to switch to the other program from the set of more than one program.

Abstract: Herein are provided systems, devices, and methods for the treatment of oral and pharyngeal disorders via the stimulation of pharyngeal muscles. Contraction of the pharyngeal muscle cells (9) is induced by activation of at least one ion channel (1) formed in at least one of a muscle cell and a neural cell. The ion channel opens (4) when it is activated by a stimulus (3). This allows ions to flow into (5) and out of (6) the cell, causing muscle contraction. This muscle contraction can be targeted towards specific muscles depending upon the condition to be treated.

Abstract: A real-time closed-loop electrical stimulation and recording device includes an electrical stimulator, a processor, two or more sample-and-hold protection circuits, and an analog front-end amplifier. The electrical stimulator is connected to a physiological tissue. The processor controls the protection circuits to sample and hold the first voltage of an analog physiological signal from a physiological tissue before the electrical stimulator generates a stimulation signal. The processor controls the protection circuits to block the analog physiological signal after the protection circuits hold the first voltage. The processor controls the protection circuits to sample and hold the second voltage of the analog physiological signal that replace the first voltage from the physiological tissue after the stimulation signal ends. The amplifier amplifies the first voltage or the second voltage to generate a detection signal and transmit the detection signal to the processor.

Abstract: Methods and systems for using sensed neural responses for informing aspects of stimulation therapy are disclosed. For example, features of evoked neural responses, such as evoked compound action potentials (ECAPs) can be used for closed-loop feedback control of stimulation parameters. Aspects of the disclosed methods and systems can differentiate between changes in the sensed neural responses that are caused by the environment at stimulating electrodes and changes in the neural responses that are caused by the environment at sensing electrodes. Embodiments determine changes in the morphology of the neural responses, which morphology changes indicate a degree of change in the stimulating environment. Algorithms and systems for assigning and tracking likelihoods for underlying electrode-tissue changes based on sensed neural responses are disclosed. The feedback control modality may be updated based on such likelihoods.

Abstract: A cardiac pacing threshold acquisition method, a pacing control method and apparatus, and a medical device. The acquisition method comprises: in a pacing test phase, using an initial pacing frequency and an initial pacing output to perform pacing on a patient; under the pacing operation, measuring first response information of the ventricle of a patient to the initial pacing frequency; according to whether an R wave is present in the first response information, adjusting pulse voltage amplitude or pulse width of the initial pacing frequency so as to obtain a cardiac pacing threshold corresponding to the patient.

Abstract: An apparatus includes: at least one electrode element; a layer of anisotropic material; a first layer of conductive adhesive positioned between a skin-facing surface of the at least one electrode element and an outwardly facing surface of the layer of anisotropic material; and a skin contact layer. The skin contact layer includes a biocompatible conductive adhesive and is disposed on a skin-facing side of the layer of anisotropic material. The first layer of conductive adhesive facilitates electrical contact between the skin-facing surface of the at least one electrode element and the outwardly facing surface of the layer of anisotropic material. A plurality of openings extend through the layer of anisotropic material.

Abstract: An electrical stimulation-based ankle muscle rehabilitation training apparatus comprising: an ankle movement providing device that provides dorsiflexion, plantarflexion, eversion, inversion, supination, and pronation operations; first and second electrode pads respectively attached to the proximal and distal portions of the tibialis anterior representative of the ankle dorsiflexor; third and fourth electrode pads respectively attached to the proximal and distal portions of the peroneus longus representative of the ankle evertor; an electrical stimulation providing unit for applying electrical stimulation to the first to fourth electrode pads; and a control unit that controls the ankle movement providing device to sequentially perform a first operation of repeating dorsiflexion and plantarflexion movements, a second operation of repeating eversion and inversion movements, and a third operation of repeating supination and pronation movements at an appropriate slow speed, and controls the electrical stimulation

Abstract: A system for facilitating resuscitation includes: a first electrode assembly having a therapy side and a first motion sensor; a second electrode assembly having a therapy side and a second motion sensor; processing circuitry operatively connected to and programmed to receive and process signals from the first and second motion sensors to estimate at least one of a chest compression depth and rate during administration of chest compressions and to compare the chest compression depth or rate to a desired range; and an output device for providing instructions to a user to administer chest compressions based on the comparison of the estimated chest compression depth or rate to the desired range. One or both of the electrode assemblies may be constructed so that the conductive therapeutic portion is able to maintain substantial conformance to the anatomy of the patient when coupled thereto.

Abstract: A cardiac treatment device, including: stimulation circuitry configured to generate a non-excitatory electrical signal which, when applied to ventricular tissue during a ventricular refractory period thereof improves a condition of heart failure in human patients; atrial arrhythmia detection circuitry; and decision circuitry which controls the stimulation circuitry to delivery said signal, also when said atrial arrhythmia detection circuitry detects an atrial arrhythmia.

Abstract: A method of selecting a combination of electrodes for use in neurostimulation includes testing combinations of electrodes in an electrode array to identify an atrial capture. The atrial capture is indicated by at least one effect on an atrium. The method includes excluding electrodes with the atrial capture to result in remaining electrodes of the electrode array, testing combinations of the remaining electrodes of the electrode array for effect on cardiac contractility and/or relaxation, and selecting a combination of electrodes from the remaining electrodes. The selected combination has both a desired effect on cardiac contractility and/or relaxation and does not have an undesired side effect.

Abstract: Methods, devices and program products are provided and include memory to store a baseline task handling (TH) pattern and TH circuitry including one or more processors. The TH circuitry is configured to perform tasks associated with one or more of collecting one or more CA signals or environmental event signals. The TH circuitry analyzes the one or more CA signals or environmental event signals, delivers therapy, detects communications requests, or maintains communications sessions with an external device. The IMD monitors a TH characteristic in connection with the performing the tasks, compares the TH characteristic to the baseline TH pattern and implements a corrective action in response to the compare of the TH characteristic and the baseline TH pattern.

Abstract: During a cardiac arrhythmia, defibrillation shocks from an implanted cardiac defibrillator are suppressed based on the sensing of electrical wavefront arrival times which indicate a supraventricular origin to the cardiac arrhythmia. In some embodiments, times of electrical wavefront arrival in at least two ventricular locations of the heart are sensed; one location being relatively superior, and one relatively inferior (e.g., relatively superior and inferior locations of a ventricular septum). In some embodiments, if the arrival time at the more inferior position is within a predetermined interval after arrival at the more superior position, delivery of defibrillation shocks are suppressed. In some embodiments, additional sensing of electrical wavefront arrival at one or more non-septal ventricular locations is performed, and defibrillation shock suppression is optionally itself suppressed if the additional sensing indicates that the wavefront initiated in a ventricular location.

Abstract: Modulated light therapy devices for treatment of dermatological disorders of the scalp are provided. An exemplary device includes a flexible printed circuit board (FPCB) supporting at least one light emitting device having an emitter height. The FPCB includes multiple interconnected panels and bending regions defined in and between at least some of the interconnected panels as to allow the FPCB to be configured in a concave shape to cover at least a portion of a cranial vertex of the patient. At least one light-transmissive layer proximate to the FPCB is configured to transmit (e.g., incoherent) light emissions generated by at least one light emitting device. At least one standoff is configured to be arranged between the FPCB and the scalp of the patient, wherein the at least one standoff includes a standoff height that exceeds the emitter height.