Abstract: A linkage assembly for a medical device, may comprise a control lever, a rotatable member rotatable about a first axis, and a plurality of linkages including a first linkage, a second linkage, and a third linkage. The first linkage may include a first end coupled to the rotatable member and a second, opposite end coupled to a first end of the second linkage. The second linkage may include the first end coupled to the second end of the first linkage and a second, opposite end coupled to a first end of the third linkage, wherein the second linkage may be rotatable about a second axis parallel with the first axis. A second end of the third linkage may translate along a third axis, and the second axis is offset from the third axis.

Abstract: A medical device is configured to sense a cardiac signal that includes far field ventricular event signals and determine a ventricular activity metric from the sensed cardiac signal. The ventricular activity metric may be representative of a ventricular rate or an atrioventricular time interval. The medical device is configured to determine an atrioventricular synchrony metric based on the ventricular activity metric and generate an output based on the atrioventricular synchrony metric. The device may include a memory configured to store data corresponding to the atrioventricular synchrony metric.

Abstract: A shock wave catheter for performing intravascular lithotripsy (IVL) is provided. The catheter includes an elongated tube having a central longitudinal axis, an enclosure sealed to the distal end of the elongated tube, and an adjustable emitter assembly disposed within the enclosure. The emitter assembly includes at least one laterally moveable or positionable shock wave generating emitter that, in a first configuration, is closer to the central longitudinal axis of the catheter, and, in a second configuration, is farther from the central longitudinal axis than in the first position. Various embodiments include support structures for the emitters, multiple balloons for positioning the emitters, helical ribbons, angled emitter ports, and other exemplary features for moving and/or positioning the emitters. Systems and methods for treating lesions in a body lumen are also provided herein.

Abstract: Methods for treating nocturia in a person are provided. The methods include assessing and identifying a person suffering from nocturia. A neurostimulator having a processor is connected to an electrical generator. The processor receives sensed data from the person and includes a sleep stimulation protocol. A determination is made as to whether the sensed data in cooperation with the sleep stimulation protocol indicates that a trigger event has occurred which defines a nocturia condition. When a trigger event has been determined, a therapy regimen provides electrical or magnetic stimulation to the leg of the person between the ankle and knee according to the sleep stimulation protocol.

Abstract: A method for stimulating a group of nerves, the method comprising: placing at least one electrode in contact with skin of a subject; applying an electrical signal to the subject through the at least one electrode, wherein the electrical signal comprises a series of pulses; and continuously randomly varying at least one of the following signal parameters: (i) a duration of each of the pulses, (ii) a time interval between each pair of pulses, and (iii) an energy value of each of the pulses, while maintaining a number of pulses per second of the electrical signal above a predetermined minimum number of pulses per second, and the energy value per pulse above a predetermined minimum energy value.

Abstract: A device implantable on a target of interest of a subject for pacemaker, neuromodulator, and/or defibrillator therapy comprises a wireless power harvesting unit configured to deliver power via resonant inductive coupling to the target tissue for stimulation in a manner that eliminates need for batteries and allows for externalized control without transcutaneous leads. The device relies exclusively on materials that resorb when exposed to biofluids in a time-controlled manner via metabolic action and hydrolysis. The materials and design choices create a thin, flexible, and lightweight form that maintain excellent biocompatibility and stable function throughout a desired period of use. Over a subsequent timeframe following the completion of therapy, the devices disappear completely through natural biological processes.

Abstract: When treating a subject using alternating electric fields (e.g., using TTFields to treat a tumor), some subjects experience an electrosensation effect when the alternating electric field switches direction. This application describes a variety of approaches for reducing or eliminating this electrosensation. More specifically, during the course of treatment using alternating electric fields, additional electrical signals that reduce the subject's sensation are applied during each of a plurality of time intervals, and these additional electrical signals interact with the relevant nerve cells to reduce the sensations.

Abstract: A system includes a subdermal sensor unit and a superficial tag. The subdermal sensor unit is injectable under skin of an ear of an animal and includes: a subdermal housing; a biometric sensor sealed in subdermal housing; and a subdermal short-range wireless transmitter configured to broadcast a set of biometric data captured by the biometric sensor at a first power level via a short-range wireless communication protocol. The superficial tag includes: a tag housing; a wireless communication module configured to receive the set of biometric data broadcast by the subdermal short-range wireless transmitter in the subdermal sensor unit and transmit the set of biometric data to an access point at a second power level, greater than the first power level, via a longer-range wireless communication protocol.

Abstract: A method comprises establishing communication between a therapy device implantable in a patient and a consumer electronic device operable by the patient. The method comprises controlling, by the consumer electronic device, a predetermined set of therapy device functions in response to patient inputs to the consumer electronic device. The method also comprises transmitting therapy data from the therapy device to the consumer electronic device. The method further comprises presenting therapy data on a display of the consumer electronic device.

Abstract: A cryosurgery coolant delivery system may include a canister body defining an inner chamber, a canister head portion coupled to the canister, and a coolant contained in the inner chamber. The coolant may include a mixture of 1,1,1,2-tetrafluoroethane (HFC-134a), 2,3,3,3-tetrafluoropropene (HFO-1234yf), pentafluoroethane (HFC-125), and difluoromethane (HFC-32). In other aspects, the coolant may include a mixture of difluoromethane (HFC-32), pentafluoroethane (HFC-125), 1,1,1,2-tetrafluoroethane (HFC-134a), 2,3,3,3-Tetrafluoroprop-1-ene (HFO-1234yf), and trans-1,3,3,3-Tetrafluoroprop-1-ene.

Abstract: A method of treating a heart, the method including providing an Implantable Pulse Generator (IPG) adapted to provide a combination of at least two treatment modalities including Cardiac Contractility Modulation therapy and one more modality selected from a group consisting of Cardiac pacing, Cardioversion, Defibrillation, Cardioversion and Defibrillation, and Cardiac Resynchronization Therapy (CRT), detecting a patient's physical condition, and selecting a combination of Cardiac Contractility Modulation therapy and at least one treatment modality from the group, and providing the combination of the Cardiac Contractility Modulation therapy and the at least one treatment modality. Related apparatus and methods are also described.

Abstract: A method, system, or device for hydration monitoring using trend analysis. The method may include measuring a physiological measurement of an individual with a sensor to obtain trend data correlating to a hydration level of the individual. The method may include removing an abnormal shift or an abnormal change from the trend data. The method may include removing abnormal shifts and changes from the raw trend data. The method may include identifying a trend parameter for the trend data, the trend parameter indicating a change in the hydration level of the body. The method may include determining a reference value for the trend parameter. The method may include identifying a change in the trend data for the trend parameter, the change in the trend data indicating a change in the hydration level of the individual.

Abstract: Described herein are therapeutic electrical muscle stimulation (EMS) apparatuses for the increasing weight loss alone or in combination with one or more physical exercises.

Abstract: A stimulation scheduling system includes a control signal generator and a controller, which can form a control loop configured to generate sets of consistent pulse schedules with a controlled degree of difficulty. The control signal generator can generate a set of consistent pulse schedules using a set of corresponding stimulation parameter distributions and provide a detection parameter based on the generation of the set of consistent pulse schedules to a controller. The controller can estimate a difficulty state based on the detection parameter and update the stimulation parameter distributions based on the estimated difficulty state. The controller can model the difficulty of generating sets of consistent pulse schedules using a difficulty distribution. The difficulty state can be a parameter of the difficulty distribution. The controller can balance the difficulty of generating sets of consistent pulse schedules against the fidelity of the generated sets of pulse schedules.

Abstract: An electrostimulation treatment device is provided for performing handheld microcurrent muscle toning treatments in absence of the assistance of another person. The electrostimulation treatment device includes a handle section disposed between a treatment end and an accessories end. The treatment end includes one or more electrodes that are configured to supply an electric microcurrent to the skin and muscles of the user. The electrodes may be being pressed against the skin to manipulate the skin and muscles such that the muscles are forced into a desired form for re-education. The accessories end is adapted to receive one or more accessory connectors and a USB connector. The USB connector is configured to be coupled with an external computing device for operating the electrostimulation treatment device. The accessory connectors facilitate coupling the electrostimulation treatment device with external accessory devices, such as a lip mask, an eye mask, or a conductive glove.

Abstract: A para-aortic blood pump device includes a blood pump, an aortic adapter, a driveline, and a driver. The blood pump includes a blood sac, a pump housing and a pressure sensor, whereas the pressure sensor is installed in the pump housing for monitoring the blood pressure inside the blood pump. The aortic adapter is a T-manifold shaped conduit connected to the blood pump and is used for connecting the blood pump with human aorta to facilitate circulatory support. The driveline allows a pneumatic communication to the blood pump in addition to transmitting the electrical blood pressure signal to the driver. The driver receives and processes the electrical blood pressure signal, decides the timing, speed and duration of blood pump fill and eject actions so as to provide counter-pulsatile circulatory support to assist human circulation.

Abstract: Systems, devices, and methods for use in delivering stimulation to the head of a patient, including examples directed to delivering electrical or other stimulation to the eye of the patient. In some examples eyepieces or eyepatches are configured to deliver electrical or other stimulus to the eye of a patient by being worn on the face of the patient.

Abstract: An implantable medical device for generating electrical stimulations, wherein the medical device is embodied to generate and emit, during a first stimulation phase, at least one first stimulation that has a first amplitude by means of energy from an energy storage element, and wherein the medical device is embodied, during a second stimulation phase following the first stimulation phase, to generate and emit at least one second stimulation that has a second amplitude by means of energy from the energy storage element, wherein the energy storage element is charged at least prior to the generation of the at least one first stimulation and after the generation of the at least one first stimulation, and wherein the medical device is embodied not to completely discharge the energy storage element by generating the at least one first stimulation. The invention furthermore relates to a method for controlling such a device.

Abstract: Systems, devices, and methods for remote monitoring and managing of patients with chronic pain are discussed. A remote monitoring system comprises one or more sensors to sense physiological or functional information from the patient, a cloud-computing device communicatively coupled to the one or more sensors, and a remote device. The cloud-computing device receives patient data including physiological or functional information, and provides on-demand cloud-based services including storing the received patient data in a cloud storage, detecting a patient behavior, and generating a sensor operation recommendation based on the detected patient behavior. The remote device can access the cloud storage and the cloud-based services, and adjust operations of the one or more sensors in accordance with the sensor operation recommendation.

Abstract: Systems and methods are provided for identifying surgical instruments, e.g., MIS instruments, including a shaft including a proximal end and a distal end sized for introduction into a patient's body, a tool tip on the distal end including an end effector, and a handpiece or connector on the proximal end. One or more identifier members may be provided on the proximal end and/or distal end of the shaft, on the handpiece, and/or on the tool tip to identify one of a type and a class of the end effector. For example, a set of surgical instruments may be provided that include identifier knobs added onto the shafts to identify different tool tips, the shafts may include different outer shapes and/or textures, or colored and/or luminescent features may be provided on the instruments.